DE69426948T2 - Automatische Bestimmung der Zellinie schwerer Leukämien durch Flusszytometrie - Google Patents

Automatische Bestimmung der Zellinie schwerer Leukämien durch Flusszytometrie

Info

Publication number
DE69426948T2
DE69426948T2 DE69426948T DE69426948T DE69426948T2 DE 69426948 T2 DE69426948 T2 DE 69426948T2 DE 69426948 T DE69426948 T DE 69426948T DE 69426948 T DE69426948 T DE 69426948T DE 69426948 T2 DE69426948 T2 DE 69426948T2
Authority
DE
Germany
Prior art keywords
leukaemias
severe
cell line
flow cytometry
automatic determination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69426948T
Other languages
English (en)
Other versions
DE69426948D1 (de
Inventor
Ben J H Verwer
Leon W M M Terstappen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of DE69426948D1 publication Critical patent/DE69426948D1/de
Application granted granted Critical
Publication of DE69426948T2 publication Critical patent/DE69426948T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57426—Specifically defined cancers leukemia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1456—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/973—Simultaneous determination of more than one analyte
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y10S436/813—Cancer
DE69426948T 1993-02-09 1994-02-01 Automatische Bestimmung der Zellinie schwerer Leukämien durch Flusszytometrie Expired - Lifetime DE69426948T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1570993A 1993-02-09 1993-02-09

Publications (2)

Publication Number Publication Date
DE69426948D1 DE69426948D1 (de) 2001-05-03
DE69426948T2 true DE69426948T2 (de) 2001-10-11

Family

ID=21773091

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69426948T Expired - Lifetime DE69426948T2 (de) 1993-02-09 1994-02-01 Automatische Bestimmung der Zellinie schwerer Leukämien durch Flusszytometrie

Country Status (4)

Country Link
US (1) US5605805A (de)
EP (1) EP0610774B1 (de)
DE (1) DE69426948T2 (de)
ES (1) ES2157227T3 (de)

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US6690817B1 (en) * 1993-08-18 2004-02-10 Applied Spectral Imaging Ltd. Spectral bio-imaging data for cell classification using internal reference
EP0708336B1 (de) * 1994-09-23 2003-08-06 Becton, Dickinson and Company Verfahren zur Unterscheidung von granulomoncytischen Progenitoren in einer Population von CD34+ Zellen
US6265150B1 (en) 1995-06-07 2001-07-24 Becton Dickinson & Company Phage antibodies
FR2754346B1 (fr) * 1996-10-07 1999-02-05 Hycel Groupe Lisabio Procede d'identification de groupes de particules et dispositif d'identification correspondant
JP3620946B2 (ja) * 1997-03-17 2005-02-16 シスメックス株式会社 スキャッタグラムの表示方法および粒子計測装置
US6316215B1 (en) 1999-12-27 2001-11-13 Edwin L. Adair Methods of cancer screening utilizing fluorescence detection techniques and selectable imager charge integration periods
US6178382B1 (en) * 1998-06-23 2001-01-23 The Board Of Trustees Of The Leland Stanford Junior University Methods for analysis of large sets of multiparameter data
CN1231761C (zh) * 1998-12-23 2005-12-14 梅德塞克股份有限公司 一种检测装置及鉴定分子的方法
WO2000067894A2 (en) * 1999-05-12 2000-11-16 Axys Pharmaceuticals, Inc. Methods of software driven flow sorting for reiterative synthesis cycles
US6750037B2 (en) * 1999-12-27 2004-06-15 Edwin L. Adair Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques
US6984498B2 (en) * 1999-12-27 2006-01-10 Adair Edwin L Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques
US6190877B1 (en) 1999-12-27 2001-02-20 Edwin L. Adair Method of cancer screening primarily utilizing non-invasive cell collection and fluorescence detection techniques
DE10002820A1 (de) * 2000-01-24 2001-08-23 Walter Schubert Aminopeptidasen-Inhibitor
US7011947B2 (en) * 2001-07-17 2006-03-14 Whitehead Institute For Biomedical Research MLL translocations specify a distinct gene expression profile, distinguishing a unique leukemia
US6846311B2 (en) 2002-04-02 2005-01-25 Acueity, Inc. Method and apparatus for in VIVO treatment of mammary ducts by light induced fluorescence
ATE336266T1 (de) * 2002-06-21 2006-09-15 Adair Edwin Lloyd Anwendung von metalloporphyrinen zur behandlung von arteriosklerose
EP1724581B1 (de) * 2004-03-03 2014-07-02 Universidad De Salamanca Verfahren zum mehrdimensionalen nachweis anomaler phänotypen in neoplastischen zellen zur verwendung bei der überwachung minimaler krankheitsniveaus mittels durchflusszytometrie
FR2873813B1 (fr) * 2004-07-30 2006-11-17 Abx Sa Procede et dispositif de caracterisation des composants cellulaires d'un liquide biologique
CN101799398B (zh) * 2005-08-02 2013-06-05 卢米尼克斯股份有限公司 用于分类微粒的方法和设备
US20070042443A1 (en) * 2005-08-17 2007-02-22 Quest Diagnostics Investments Incorporated Hematopoietic cell phenotyping using free circulating cellular markers
US7321843B2 (en) * 2005-09-30 2008-01-22 Universidad De Salamanca Method for generating new flow cytometry data files containing an infinite number of dimensions based on data estimation
EP1777523A1 (de) * 2005-10-19 2007-04-25 INSERM (Institut National de la Santé et de la Recherche Médicale) In-vitro-Verfahren zur Prognose einer Tumorprogression und des Ergebnisses bei einem Patienten sowie Mittel zur Durchführung dieses Verfahrens
EP2860247A1 (de) 2007-08-21 2015-04-15 Nodality, Inc. Diagnose-, Prognose- und Behandlungsverfahren
US7653509B2 (en) * 2007-08-29 2010-01-26 Verity Software House Probability state models
US8617804B2 (en) * 2007-12-28 2013-12-31 National University Corporation Hokkaido University Method of detecting leukemic cell
US20090269773A1 (en) * 2008-04-29 2009-10-29 Nodality, Inc. A Delaware Corporation Methods of determining the health status of an individual
US20090291458A1 (en) * 2008-05-22 2009-11-26 Nodality, Inc. Method for Determining the Status of an Individual
US8227202B2 (en) * 2008-07-10 2012-07-24 Nodality, Inc. Methods for diagnosis, prognosis and methods of treatment
US8399206B2 (en) * 2008-07-10 2013-03-19 Nodality, Inc. Methods for diagnosis, prognosis and methods of treatment
FR2935802B1 (fr) * 2008-09-05 2012-12-28 Horiba Abx Sas Procede et dispositif de classification, de visualisation et d'exploration de donnees biologiques
WO2010045651A1 (en) * 2008-10-17 2010-04-22 Nodality, Inc. Methods for analyzing drug response
EP2359164A4 (de) * 2008-12-10 2012-05-30 Abqmr Inc Kernmagnetresonanzgerät, verfahren und zugehörige technologie
WO2010135608A1 (en) * 2009-05-20 2010-11-25 Nodality, Inc. Methods for diagnosis, prognosis and methods of treatment
US8841104B2 (en) 2010-04-21 2014-09-23 Nanomr, Inc. Methods for isolating a target analyte from a heterogeneous sample
US9428547B2 (en) 2010-04-21 2016-08-30 Dna Electronics, Inc. Compositions for isolating a target analyte from a heterogeneous sample
US20110262989A1 (en) 2010-04-21 2011-10-27 Nanomr, Inc. Isolating a target analyte from a body fluid
US9476812B2 (en) 2010-04-21 2016-10-25 Dna Electronics, Inc. Methods for isolating a target analyte from a heterogeneous sample
WO2014028534A2 (en) * 2012-08-13 2014-02-20 Beckman Coulter, Inc. Leukemia classification using cpd data
US9599610B2 (en) 2012-12-19 2017-03-21 Dnae Group Holdings Limited Target capture system
US9804069B2 (en) 2012-12-19 2017-10-31 Dnae Group Holdings Limited Methods for degrading nucleic acid
US10000557B2 (en) 2012-12-19 2018-06-19 Dnae Group Holdings Limited Methods for raising antibodies
US9434940B2 (en) 2012-12-19 2016-09-06 Dna Electronics, Inc. Methods for universal target capture
US9551704B2 (en) 2012-12-19 2017-01-24 Dna Electronics, Inc. Target detection
US9995742B2 (en) 2012-12-19 2018-06-12 Dnae Group Holdings Limited Sample entry
CA2927712A1 (en) 2013-10-24 2015-04-30 Ospedale San Raffaele S.R.L. Method for the genetic modification of haematopoietic stem and progenitor cells (hspcs) and the use of genetically modified hspcs in gene therapy
CN106255873B (zh) * 2014-04-10 2019-06-04 深圳迈瑞生物医疗电子股份有限公司 一种进行自动补偿的方法、装置及相应的流式细胞分析仪
US9965702B1 (en) 2016-12-27 2018-05-08 Cesar Angeletti Method for analysis and interpretation of flow cytometry data
FR3078777B1 (fr) * 2018-03-07 2020-11-13 Alain Rousseau Procede d’analyse d’un echantillon biologique contenant des cellules biologiques, et appareil d’analyse pour la mise en œuvre du procede d’analyse

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* Cited by examiner, † Cited by third party
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US4661913A (en) * 1984-09-11 1987-04-28 Becton, Dickinson And Company Apparatus and method for the detection and classification of articles using flow cytometry techniques
US4845653A (en) * 1987-05-07 1989-07-04 Becton, Dickinson And Company Method of displaying multi-parameter data sets to aid in the analysis of data characteristics
US5234816A (en) * 1991-07-12 1993-08-10 Becton, Dickinson And Company Method for the classification and monitoring of leukemias

Also Published As

Publication number Publication date
EP0610774A1 (de) 1994-08-17
US5605805A (en) 1997-02-25
DE69426948D1 (de) 2001-05-03
EP0610774B1 (de) 2001-03-28
ES2157227T3 (es) 2001-08-16

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