DE69429436T2 - Kryokonservierung von kultivierten gewebeäquivalenten - Google Patents

Kryokonservierung von kultivierten gewebeäquivalenten

Info

Publication number
DE69429436T2
DE69429436T2 DE69429436T DE69429436T DE69429436T2 DE 69429436 T2 DE69429436 T2 DE 69429436T2 DE 69429436 T DE69429436 T DE 69429436T DE 69429436 T DE69429436 T DE 69429436T DE 69429436 T2 DE69429436 T2 DE 69429436T2
Authority
DE
Germany
Prior art keywords
cultured tissue
equivalent
cryopreservation
vitro
cryoprotectant solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69429436T
Other languages
English (en)
Other versions
DE69429436D1 (de
Inventor
M Wilkins
R Watson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organogenesis Inc
Original Assignee
Organogenesis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organogenesis Inc filed Critical Organogenesis Inc
Application granted granted Critical
Publication of DE69429436D1 publication Critical patent/DE69429436D1/de
Publication of DE69429436T2 publication Critical patent/DE69429436T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0205Chemical aspects
    • A01N1/021Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
DE69429436T 1993-09-15 1994-09-14 Kryokonservierung von kultivierten gewebeäquivalenten Expired - Fee Related DE69429436T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/121,377 US5518878A (en) 1993-09-15 1993-09-15 Cryopreservation of cultured skin or cornea equivalents with agitation
PCT/US1994/010042 WO1995007611A1 (en) 1993-09-15 1994-09-14 Cryopreservation of cultured tissue equivalents

Publications (2)

Publication Number Publication Date
DE69429436D1 DE69429436D1 (de) 2002-01-24
DE69429436T2 true DE69429436T2 (de) 2002-07-18

Family

ID=22396314

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69429436T Expired - Fee Related DE69429436T2 (de) 1993-09-15 1994-09-14 Kryokonservierung von kultivierten gewebeäquivalenten

Country Status (16)

Country Link
US (1) US5518878A (de)
EP (1) EP0719084B1 (de)
JP (1) JPH09505032A (de)
KR (1) KR100361357B1 (de)
AT (1) ATE210373T1 (de)
AU (1) AU683301B2 (de)
CA (1) CA2182814C (de)
CY (1) CY2364B1 (de)
DE (1) DE69429436T2 (de)
DK (1) DK0719084T3 (de)
ES (1) ES2169734T3 (de)
FI (1) FI113833B (de)
NO (1) NO311631B1 (de)
NZ (1) NZ273514A (de)
PT (1) PT719084E (de)
WO (1) WO1995007611A1 (de)

Families Citing this family (37)

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US5723282A (en) * 1991-07-08 1998-03-03 The American National Red Cross Method of preparing organs for vitrification
US5891617A (en) * 1993-09-15 1999-04-06 Organogenesis Inc. Cryopreservation of harvested skin and cultured skin or cornea equivalents by slow freezing
CN1127288C (zh) 1994-11-09 2003-11-12 塞莱顿科学有限责任公司 愈伤材料及其保存方法
US20040002772A1 (en) * 1995-04-28 2004-01-01 Organogenesis, Inc. Tissue equivalents with perforations for improved integration to host tissues and methods for producing perforated tissue equivalents
US5689961A (en) 1996-01-30 1997-11-25 Organogenesis Inc. Ice seeding apparatus for cryopreservation systems
US6630001B2 (en) 1998-06-24 2003-10-07 International Heart Institute Of Montana Foundation Compliant dehyrated tissue for implantation and process of making the same
EP1121015B2 (de) * 1998-10-14 2012-02-08 Katrina T. Forest Verfahren zur verglasung einer biologischen probe
AU2004200933B2 (en) * 1998-10-14 2005-08-11 Katrina T Forest Method for vitrification of a biological specimen
US6403376B1 (en) * 1998-11-16 2002-06-11 General Hospital Corporation Ultra rapid freezing for cell cryopreservation
US6300130B1 (en) * 1998-11-16 2001-10-09 The General Hospital Corporation And University Of Massachusetts Ultra rapid freezing for cell cryopreservation
AU769637B2 (en) 1998-11-19 2004-01-29 Organogenesis Inc. Bioengineered tissue constructs and methods for producing and using them
US6358739B1 (en) 1999-04-12 2002-03-19 Modex Therapeutiques, S.A. Transiently immortalized cells
US6194137B1 (en) * 1999-04-13 2001-02-27 Organ Recovery Systems, Inc. Method of cryopreservation of blood vessels by vitrification
US6352708B1 (en) 1999-10-14 2002-03-05 The International Heart Institute Of Montana Foundation Solution and method for treating autologous tissue for implant operation
US6878543B1 (en) 1999-10-25 2005-04-12 Nsgene Sa Cultures of GFAP+ nestin+ cells that differentiate to neurons
KR20010008306A (ko) * 2000-11-22 2001-02-05 김진경 저온처리 후 조직 배양 방법
DE10061968A1 (de) * 2000-12-13 2002-06-20 Friedrich Hoffmann Verfahren und Vorrichtung zum Einfrieren von Hornhautgewebe
JP2004520828A (ja) * 2000-12-27 2004-07-15 オーテック・インターナショナル,インコーポレイテッド 凍結保存された複合生体構築物の製造方法および該方法から得られる製造物
DE10151296A1 (de) 2001-10-17 2003-04-30 Boehringer Ingelheim Pharma Keratinozyten verwendbar als biologisch aktive Substanz bei der Behandlung von Wunden
US20030096412A1 (en) * 2001-11-20 2003-05-22 Cassell Allan J. Method of preparing biological materials for cryopreservation using pre-chilled protectant
AU2003241107B2 (en) 2002-05-16 2009-09-03 Absorber Ab Method of isolating an endothelial cell and method of donor specific crossmatching
JP5100078B2 (ja) 2006-10-05 2012-12-19 株式会社セルバンク 組織由来細胞の凍結保存方法
EP2229581A2 (de) * 2008-01-17 2010-09-22 Vance Products Incorporated D/B/A Cook Urological Incorporated Schnellabkühlungsvorrichtung für verglasungsoperationen
CA2753291C (en) * 2009-02-23 2017-08-15 Cell & Tissue Systems, Inc. Method for ice-free cryopreservation of tissue
WO2012031162A1 (en) 2010-09-01 2012-03-08 Doris Taylor Methods of recellularizing a tissue or organ for improved transplantability
JP6012164B2 (ja) 2011-11-25 2016-10-25 住友化学株式会社 多能性幹細胞由来の組織の凍結保存方法
JP5915977B2 (ja) * 2011-11-29 2016-05-11 学校法人明治大学 凍結細胞シートの製造方法
WO2013174769A1 (en) 2012-05-25 2013-11-28 Boehringer Ingelheim International Gmbh Use of keratinocytes as a biologically active substance in the treatment of wounds, such as diabetic wounds, optionally in combination with a dpp-4 inhibitor
TW201422155A (zh) * 2012-07-06 2014-06-16 Arigos Biomedical Inc 以氣體灌注快速冷卻與升溫預防玻璃質化組織受熱-力破壞的方法與裝置
JP6746313B2 (ja) 2012-08-01 2020-08-26 ユナイテッド セラピューティクス コーポレイション プロスタサイクリン処理された内皮前駆細胞による肺動脈性高血圧症の処置
EP2879682B1 (de) 2012-08-01 2018-03-21 United Therapeutics Corporation Behandlung von pulmonal-arteriellem hochdruck mit mesenchymalen stammzellen
KR101480806B1 (ko) 2012-09-19 2015-01-09 한국생산기술연구원 스캐폴드를 이용한 세포 또는 조직 동결 방법, 및 세포 또는 조직 동결용 키트
JP6431850B2 (ja) 2013-01-09 2018-11-28 ユナイテッド セラピューティクス コーポレイション プロスタサイクリンおよび間葉系幹細胞による脈管障害の処置
ES2705043T3 (es) * 2013-03-13 2019-03-21 Stratatech Corp Criopreservación de sustitutos de piel humana viables
SG11201510671SA (en) * 2013-07-02 2016-01-28 Austrianova Singapore Pte Ltd A method of freeze-drying encapsulated cells, freeze-dried encapsulated cells, compositions containing freeze-dried encapsulated cells and uses of such cells and compositions
JP2018512172A (ja) 2015-03-26 2018-05-17 ミロマトリックス メディカル インコーポレイテッド ガス充填された脱細胞化細胞外マトリックス
ES2927406T3 (es) 2016-10-24 2022-11-04 United Therapeutics Corp Potenciación de las propiedades inmunomoduladoras de las MSC mediante treprostinil

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4539716A (en) * 1981-03-19 1985-09-10 Massachusetts Institute Of Technology Fabrication of living blood vessels and glandular tissues
US4546500A (en) * 1981-05-08 1985-10-15 Massachusetts Institute Of Technology Fabrication of living blood vessels and glandular tissues
US4485096A (en) * 1982-02-26 1984-11-27 Massachusetts Institute Of Technology Tissue-equivalent and method for preparation thereof
US4485097A (en) * 1982-05-26 1984-11-27 Massachusetts Institute Of Technology Bone-equivalent and method for preparation thereof
US5084377A (en) * 1984-09-19 1992-01-28 Larry Rowan Cryogenic suspension method
US4604346A (en) * 1984-10-09 1986-08-05 Massachusetts Institute Of Technology Skin-equivalent prepared by the use of punch biopsy
IT1207525B (it) * 1987-06-23 1989-05-25 Ist Naz Ric Sul Cancro Metodo per la preservazione difogli trapiantabili di epitelio coltivato in vitro vitale.
US4837379A (en) * 1988-06-02 1989-06-06 Organogenesis Inc. Fibrin-collagen tissue equivalents and methods for preparation thereof
US5145770A (en) * 1990-06-04 1992-09-08 Biosurface Technology, Inc. Cryopreservation of cultured epithelial sheets

Also Published As

Publication number Publication date
FI961124A (fi) 1996-03-15
PT719084E (pt) 2002-05-31
KR960704461A (ko) 1996-10-09
EP0719084A4 (de) 1998-06-10
NO961048L (no) 1996-03-14
NZ273514A (en) 1997-10-24
EP0719084B1 (de) 2001-12-12
FI961124A0 (fi) 1996-03-11
DE69429436D1 (de) 2002-01-24
AU7683194A (en) 1995-04-03
EP0719084A1 (de) 1996-07-03
DK0719084T3 (da) 2002-04-08
CY2364B1 (en) 2004-06-04
KR100361357B1 (ko) 2004-12-30
ES2169734T3 (es) 2002-07-16
CA2182814A1 (en) 1995-03-23
US5518878A (en) 1996-05-21
WO1995007611A1 (en) 1995-03-23
FI113833B (fi) 2004-06-30
JPH09505032A (ja) 1997-05-20
CA2182814C (en) 1999-02-02
NO961048D0 (no) 1996-03-14
NO311631B1 (no) 2001-12-27
ATE210373T1 (de) 2001-12-15
AU683301B2 (en) 1997-11-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee