US6582959B2
(en)
|
1991-03-29 |
2003-06-24 |
Genentech, Inc. |
Antibodies to vascular endothelial cell growth factor
|
US6228879B1
(en)
|
1997-10-16 |
2001-05-08 |
The Children's Medical Center |
Methods and compositions for inhibition of angiogenesis
|
US8143283B1
(en)
*
|
1993-03-01 |
2012-03-27 |
The Children's Medical Center Corporation |
Methods for treating blood-born tumors with thalidomide
|
US6114355A
(en)
*
|
1993-03-01 |
2000-09-05 |
D'amato; Robert |
Methods and compositions for inhibition of angiogenesis
|
US5629327A
(en)
*
|
1993-03-01 |
1997-05-13 |
Childrens Hospital Medical Center Corp. |
Methods and compositions for inhibition of angiogenesis
|
US20040248799A1
(en)
*
|
1993-05-27 |
2004-12-09 |
Holaday John W. |
Compositions and methods for treating cancer and hyperproliferative disorders
|
US6805865B1
(en)
|
1993-05-27 |
2004-10-19 |
Entremed, Inc. |
Compositions and methods for treating cancer and hyperproliferative disorders
|
DE4422237A1
(de)
*
|
1994-06-24 |
1996-01-04 |
Gruenenthal Gmbh |
Verwendung von Lactamverbindungen als pharmazeutische Wirkstoffe
|
US6429221B1
(en)
*
|
1994-12-30 |
2002-08-06 |
Celgene Corporation |
Substituted imides
|
US6440729B1
(en)
|
1995-06-30 |
2002-08-27 |
University Of Kansas Medical Center |
Treating angiogenesis-mediated diseases with the α2 monomer of type IV collagen
|
US6358735B1
(en)
|
1995-06-30 |
2002-03-19 |
University Of Kansas Medical Center |
Method for inhibiting angiogenesis and tumors with the isolated NC1 α3 chain monomer of type IV collagen
|
US6518281B2
(en)
*
|
1995-08-29 |
2003-02-11 |
Celgene Corporation |
Immunotherapeutic agents
|
US6346510B1
(en)
|
1995-10-23 |
2002-02-12 |
The Children's Medical Center Corporation |
Therapeutic antiangiogenic endostatin compositions
|
JP3263598B2
(ja)
*
|
1995-11-01 |
2002-03-04 |
有限会社ドット |
経鼻吸収用生理活性ペプチド組成物
|
DK2177517T3
(da)
*
|
1996-07-24 |
2011-11-21 |
Celgene Corp |
Aminosubstitueret 2-(2,6-dioxopiperidin-3-yl)-phthalimid til at nedsætte TNF-alfa-niveauer
|
EP2070920B8
(de)
*
|
1996-07-24 |
2011-04-27 |
Celgene Corporation |
Substituierte 2-(2,6-Dioxopiperidin-3-yl)-phthalimide und Oxoisoindoline und Verfahren zur Verringerung der TNF-Alpha-Stufen
|
HU228769B1
(en)
*
|
1996-07-24 |
2013-05-28 |
Celgene Corp |
Substituted 2(2,6-dioxopiperidin-3-yl)phthalimides and -1-oxoisoindolines and their use for production of pharmaceutical compositions for mammals to reduce the level of tnf-alpha
|
US5798368A
(en)
*
|
1996-08-22 |
1998-08-25 |
Celgene Corporation |
Tetrasubstituted 2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolines and method of reducing TNFα levels
|
US6281230B1
(en)
*
|
1996-07-24 |
2001-08-28 |
Celgene Corporation |
Isoindolines, method of use, and pharmaceutical compositions
|
US5635517B1
(en)
*
|
1996-07-24 |
1999-06-29 |
Celgene Corp |
Method of reducing TNFalpha levels with amino substituted 2-(2,6-dioxopiperidin-3-YL)-1-oxo-and 1,3-dioxoisoindolines
|
US5955496A
(en)
*
|
1996-08-13 |
1999-09-21 |
The Regents Of The University Of California |
Dihydroxy-oxy-eicosadienoates
|
DK1586322T3
(da)
*
|
1996-11-05 |
2008-12-01 |
Childrens Medical Center |
Sammensætninger indeholdende thalidomid og dextamethason til behandling af cancer
|
US6028060A
(en)
*
|
1997-01-29 |
2000-02-22 |
Vanderbilt University |
Treatment of chronic inflammatory diseases with CM101/GBS toxin
|
US5858991A
(en)
|
1997-01-29 |
1999-01-12 |
Vanderbilt University |
Facilitation of wound healing with CM101/GBS toxin
|
US5981508A
(en)
*
|
1997-01-29 |
1999-11-09 |
Vanderbilt University |
Facilitation of repair of neural injury with CM101/GBS toxin
|
US6670337B1
(en)
|
1998-01-29 |
2003-12-30 |
Yeda Reaearch And Development Co., Ltd. |
Facilitation of wound healing with CM101/GBS toxin
|
US6593291B1
(en)
|
1997-02-06 |
2003-07-15 |
Entremed, Inc. |
Compositions and methods of use of ligands that bind components of the blood coagulation/clotting pathway for the treatment of cancer and angiogenic-based disease
|
US5994388A
(en)
*
|
1997-03-18 |
1999-11-30 |
The Children's Medical Center Corporation |
Cytochalasin and isoindolinone derivatives as inhibitors of angiogenesis
|
US6265388B1
(en)
|
1997-03-21 |
2001-07-24 |
President And Fellows Of Harvard College |
Antisense inhibition of angiogenin expression
|
US6174695B1
(en)
|
1997-08-12 |
2001-01-16 |
The Regents Of The University Of California |
Epoxide hydrolase inhibitor methods
|
EP1017389A1
(de)
|
1997-08-25 |
2000-07-12 |
Harold Brem |
Verwendung von gefässneubildungshemmern zur vorbeugung von gewebeverklebung und übermässiger narbenbildung
|
US5955476A
(en)
*
|
1997-11-18 |
1999-09-21 |
Celgene Corporation |
Substituted 2-(2,6-dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing inflammatory cytokine levels
|
EP1308444B1
(de)
*
|
1997-11-18 |
2006-05-24 |
Celgene Corporation |
Substituierte 2-(2,6-dioxo-3-fluoropiperidine-3-yl)-isoindoline und ihre Verwendung zum reduzieren des TNF-alpha spiegels
|
CN100390163C
(zh)
*
|
1998-03-16 |
2008-05-28 |
赛尔金有限公司 |
2-(2,6-二氧哌啶-3-基)-异二氢吲哚衍生物、其制法及其作为炎性细胞因子抑制剂的用途
|
US6673828B1
(en)
*
|
1998-05-11 |
2004-01-06 |
Children's Medical Center Corporation |
Analogs of 2-Phthalimidinoglutaric acid
|
US6482802B1
(en)
|
1998-05-11 |
2002-11-19 |
Endowment For Research In Human Biology, Inc. |
Use of neomycin for treating angiogenesis-related diseases
|
CA2331461C
(en)
|
1998-05-11 |
2008-10-07 |
Entremed, Inc. |
Analogs of 2-phthalimidinoglutaric acid and their use as inhibitors of angiogenesis
|
US8197430B1
(en)
*
|
1998-05-22 |
2012-06-12 |
Biopheresis Technologies, Inc. |
Method and system to remove cytokine inhibitor in patients
|
US6620382B1
(en)
|
1998-05-22 |
2003-09-16 |
Biopheresis Technologies, Llc. |
Method and compositions for treatment of cancers
|
US8609614B2
(en)
|
1998-07-22 |
2013-12-17 |
Vanderbilt University |
GBS toxin receptor compositions and methods of use
|
US6576613B1
(en)
*
|
1998-07-24 |
2003-06-10 |
Corvas International, Inc. |
Title inhibitors of urokinase
|
US6703050B1
(en)
*
|
1998-09-04 |
2004-03-09 |
The Regents Of The University Of Michigan |
Methods and compositions for the prevention or treatment of cancer
|
US6537554B1
(en)
|
1998-09-10 |
2003-03-25 |
Curagen Corporation |
Nucleotide sequences and amino acid sequences of secreted proteins involved in angiogenesis
|
US6231889B1
(en)
*
|
1998-09-21 |
2001-05-15 |
Chronorx, Llc |
Unit dosage forms for the treatment of herpes simplex
|
US6630488B1
(en)
|
1998-09-21 |
2003-10-07 |
Biochem Pharma, Inc. |
Quinolizinones as integrin inhibitors
|
US6596690B2
(en)
|
1998-10-06 |
2003-07-22 |
The United States Of America As Represented By The Department Of Health And Human Services |
Vasostatin as marrow protectant
|
FR2784580B1
(fr)
*
|
1998-10-16 |
2004-06-25 |
Biosepra Inc |
Microspheres de polyvinyl-alcool et procedes de fabrication de celles-ci
|
US20030013739A1
(en)
*
|
1998-12-23 |
2003-01-16 |
Pharmacia Corporation |
Methods of using a combination of cyclooxygenase-2 selective inhibitors and thalidomide for the treatment of neoplasia
|
US7238711B1
(en)
*
|
1999-03-17 |
2007-07-03 |
Cambridge University Technical Services Ltd. |
Compounds and methods to inhibit or augment an inflammatory response
|
AU2612100A
(en)
*
|
1999-01-13 |
2000-08-01 |
Rockefeller University, The |
Methods of promoting or enhancing interleukin-12 production through administration of thalidomide
|
DE60023123T2
(de)
|
1999-03-18 |
2006-06-22 |
Celgene Corp. |
Substituierte 1-oxo- und 1,3-dioxoisoindoline und ihre verwendung in pharmazeutischen zusammensetzungen zur senkung des spiegels inflammatorisch wirkender cytokine
|
DK1040838T3
(da)
*
|
1999-03-31 |
2003-05-26 |
Gruenenthal Gmbh |
Stabil vandig opløsning af 3-(1-oxo-1,3-dihydroisoindol-2-yl )piperidin-2,6-dion
|
US7629360B2
(en)
*
|
1999-05-07 |
2009-12-08 |
Celgene Corporation |
Methods for the treatment of cachexia and graft v. host disease
|
US6468990B1
(en)
*
|
1999-05-17 |
2002-10-22 |
Queen's University At Kingston |
Method of inhibiting binding of nerve growth factor to p75 NTR receptor
|
US6673843B2
(en)
|
1999-06-30 |
2004-01-06 |
Emory University |
Curcumin and curcuminoid inhibition of angiogenesis
|
US6916843B1
(en)
*
|
1999-08-11 |
2005-07-12 |
The United States Of America As Represented By The Department Of Health And Human Services |
Anti-inflammatory actions of cytochrome P450 expoxygenase-derived eicosanoids
|
US7087592B1
(en)
|
1999-08-23 |
2006-08-08 |
Entre Med, Inc. |
Compositions comprising purified 2-methoxyestradiol and methods of producing same
|
US20040214783A1
(en)
|
2002-05-08 |
2004-10-28 |
Terman David S. |
Compositions and methods for treatment of neoplastic disease
|
AU783238B2
(en)
|
1999-11-10 |
2005-10-06 |
Innatus Corporation |
Method and system to remove cytokine inhibitor in patients
|
US6204270B1
(en)
*
|
1999-11-12 |
2001-03-20 |
Eyal S. Ron |
Ophthalmic and mucosal preparations
|
ATE364689T1
(de)
|
1999-11-18 |
2007-07-15 |
Dendreon Corp |
Nukleinsäuren, welche für endotheliasen kodieren, endotheliasen, sowie deren verwendung
|
US6379708B1
(en)
*
|
1999-11-20 |
2002-04-30 |
Cytologic, Llc |
Method for enhancing immune responses in mammals
|
WO2001041755A2
(en)
*
|
1999-12-02 |
2001-06-14 |
The Regents Of The University Of Michigan |
Topical compositions comprising thalidomide for the treatment of inflammatory diseases
|
US7182953B2
(en)
|
1999-12-15 |
2007-02-27 |
Celgene Corporation |
Methods and compositions for the prevention and treatment of atherosclerosis restenosis and related disorders
|
US6699899B1
(en)
*
|
1999-12-21 |
2004-03-02 |
Celgene Corporation |
Substituted acylhydroxamic acids and method of reducing TNFα levels
|
US7700341B2
(en)
*
|
2000-02-03 |
2010-04-20 |
Dendreon Corporation |
Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon
|
CN1121218C
(zh)
*
|
2000-03-08 |
2003-09-17 |
台湾东洋药品工业股份有限公司 |
酞胺哌啶酮在治疗肝细胞癌的药物组合物中的应用
|
US20030212022A1
(en)
*
|
2001-03-23 |
2003-11-13 |
Jean-Marie Vogel |
Compositions and methods for gene therapy
|
US8697137B2
(en)
|
2000-03-24 |
2014-04-15 |
Biosphere Medical, Inc. |
Methods of using microspheres for active embolization
|
KR20030003708A
(ko)
*
|
2000-03-31 |
2003-01-10 |
셀진 코포레이션 |
시클로옥시게나제-2 활성의 저해
|
WO2001087306A2
(en)
*
|
2000-05-15 |
2001-11-22 |
Celgene Corp. |
Compositions and methods for the treatment of colorectal cancer
|
NZ522767A
(en)
|
2000-05-15 |
2004-07-30 |
Celgene Corp |
Thalidomide and a topoisomerase inhibitor for the treatment of cancer
|
US20030104573A1
(en)
*
|
2000-09-11 |
2003-06-05 |
Shimkets Richard A. |
Nucleotide sequences and amino acid sequences of secreted proteins involved in angiogenesis
|
US6458810B1
(en)
|
2000-11-14 |
2002-10-01 |
George Muller |
Pharmaceutically active isoindoline derivatives
|
DE60130799T2
(de)
*
|
2000-11-30 |
2008-07-17 |
Children's Medical Center Corp., Boston |
Synthese von 4-aminothalidomid enantiomeren
|
US20040121945A1
(en)
*
|
2000-12-15 |
2004-06-24 |
Hong Liang |
Compositions and methods for inhibiting endothelial cell proliferation
|
EP1226824A1
(de)
*
|
2001-01-24 |
2002-07-31 |
TTY Biopharm Company Limited |
Verwendung von Thalidomid zur Behandlung von Leberzellkarzinom
|
US6632835B2
(en)
|
2001-02-22 |
2003-10-14 |
Nanodesign Inc. |
Dibenzo[c]chromen-6-one derivatives as anti-cancer agents
|
EP1389203B8
(de)
*
|
2001-02-27 |
2010-03-10 |
The Governement of the United States of America, represented by The Secretary Department of Health and Human services |
Analoga von thalidomid als angiogeneseinhibitoren
|
CN1518447A
(zh)
*
|
2001-04-23 |
2004-08-04 |
�������Ǵ�ѧר������� |
作为抗血管生成剂的新的苯邻二甲酰亚胺模拟物的合成和评估
|
CA2451942A1
(en)
*
|
2001-07-27 |
2003-02-13 |
Munirathinam Sundaramoorthy |
Crystallized structure of type iv collagen nc1 domain hexamer
|
DE60231989D1
(de)
*
|
2001-08-06 |
2009-05-28 |
Childrens Medical Center |
Antiangiogenese wirkung von stickstoffsubstituierten thalidomid-analoga
|
GB0125659D0
(en)
*
|
2001-10-25 |
2001-12-19 |
Ssl Int Plc |
Spermicides
|
US20030134794A1
(en)
*
|
2001-11-20 |
2003-07-17 |
Madison Edwin L. |
Nucleic acid molecules encoding serine protease 17, the encoded polypeptides and methods based thereon
|
US20030139469A1
(en)
*
|
2002-01-23 |
2003-07-24 |
The Regents Of The University Of California |
Use of inhibitors of soluble epoxide hydrolase to inhibit vascular smooth muscle cell proliferation
|
AU2003220173A1
(en)
*
|
2002-03-08 |
2003-09-22 |
Abgent, Inc. |
Detection and modulation of slit and roundabount (robo) mediated angiogenesis and uses thereof
|
JP2005529080A
(ja)
*
|
2002-03-08 |
2005-09-29 |
エモリー ユニバーシティ |
腫瘍の増殖および脈管形成のサプレッサとしての新規のクルクミノイド−第VIIa因子構築物
|
EP1496916A2
(de)
*
|
2002-04-09 |
2005-01-19 |
Greenville Hospital System |
Metastasen-modulierende wirkung von hochsulfierten oligosacchariden
|
US7968569B2
(en)
|
2002-05-17 |
2011-06-28 |
Celgene Corporation |
Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione
|
CA2486141A1
(en)
|
2002-05-17 |
2003-11-27 |
Celgene Corporation |
Methods and compositions using selective cytokine inhibitory drugs for treatment and management of cancers and other diseases
|
NZ549175A
(en)
|
2002-05-17 |
2007-12-21 |
Celgene Corp |
Methods and compositions using immunomodulatory compounds for treatment and management of cancers and other diseases
|
US7393862B2
(en)
|
2002-05-17 |
2008-07-01 |
Celgene Corporation |
Method using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for treatment of certain leukemias
|
USRE48890E1
(en)
|
2002-05-17 |
2022-01-11 |
Celgene Corporation |
Methods for treating multiple myeloma with 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione after stem cell transplantation
|
US7323479B2
(en)
*
|
2002-05-17 |
2008-01-29 |
Celgene Corporation |
Methods for treatment and management of brain cancer using 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-methylisoindoline
|
US20100129363A1
(en)
*
|
2002-05-17 |
2010-05-27 |
Zeldis Jerome B |
Methods and compositions using pde4 inhibitors for the treatment and management of cancers
|
US20040001801A1
(en)
*
|
2002-05-23 |
2004-01-01 |
Corvas International, Inc. |
Conjugates activated by cell surface proteases and therapeutic uses thereof
|
WO2004002418A2
(en)
*
|
2002-06-26 |
2004-01-08 |
Entremed, Inc |
Compositions and methods comprising protein activated receptor antagonists
|
ATE491725T1
(de)
|
2002-07-15 |
2011-01-15 |
Univ Texas |
Antikörper mit bindung an anionische phospholipide und aminophospholipide und ihre verwendung bei der behandlung von virusinfektionen
|
US7642252B2
(en)
*
|
2002-07-22 |
2010-01-05 |
Chemgenex Pharmaceuticals, Inc. |
Angiogenesis inhibition by cephalotaxine alkaloids, derivatives, compositions and uses thereof
|
US7888389B2
(en)
*
|
2002-07-23 |
2011-02-15 |
The Regents Of The University Of Michigan |
Tetrapropylammonium tetrathiomolybdate and related compounds for anti-angiogenic therapies
|
US8404716B2
(en)
|
2002-10-15 |
2013-03-26 |
Celgene Corporation |
Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine
|
ZA200503024B
(en)
*
|
2002-10-15 |
2006-11-29 |
Celgene Corp |
Selective cytokine inhibitory drugs for treating myelodysplastic syndrome
|
US11116782B2
(en)
|
2002-10-15 |
2021-09-14 |
Celgene Corporation |
Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine
|
US7189740B2
(en)
|
2002-10-15 |
2007-03-13 |
Celgene Corporation |
Methods of using 3-(4-amino-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myelodysplastic syndromes
|
EP1900369A1
(de)
|
2002-10-15 |
2008-03-19 |
Celgene Corporation |
Verfahren zur Verwendung von und Zusammensetzungen mit immunmodulatorischen Verbindungen für die Therapie und Behandlung des myelodysplastischen Syndroms
|
US8404717B2
(en)
*
|
2002-10-15 |
2013-03-26 |
Celgene Corporation |
Methods of treating myelodysplastic syndromes using lenalidomide
|
US20040087558A1
(en)
*
|
2002-10-24 |
2004-05-06 |
Zeldis Jerome B. |
Methods of using and compositions comprising selective cytokine inhibitory drugs for treatment, modification and management of pain
|
US20050203142A1
(en)
*
|
2002-10-24 |
2005-09-15 |
Zeldis Jerome B. |
Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain
|
KR20050061586A
(ko)
*
|
2002-10-31 |
2005-06-22 |
셀진 코포레이션 |
황반 변성의 치료를 위한 조성물
|
US7776907B2
(en)
*
|
2002-10-31 |
2010-08-17 |
Celgene Corporation |
Methods for the treatment and management of macular degeneration using cyclopropyl-N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-3-oxoisoindoline-4-yl}carboxamide
|
US20040091455A1
(en)
*
|
2002-10-31 |
2004-05-13 |
Zeldis Jerome B. |
Methods of using and compositions comprising immunomodulatory compounds for treatment and management of macular degeneration
|
US8034831B2
(en)
*
|
2002-11-06 |
2011-10-11 |
Celgene Corporation |
Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies
|
KR100923173B1
(ko)
|
2002-11-06 |
2009-10-22 |
셀진 코포레이션 |
암 및 다른 질환의 치료 및 관리를 위한 선택적 시토킨억제 약물의 사용 방법 및 그 조성물
|
US7563810B2
(en)
*
|
2002-11-06 |
2009-07-21 |
Celgene Corporation |
Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases
|
CA2504460A1
(en)
*
|
2002-11-12 |
2004-05-27 |
Peter G. Klimko |
Histone deacetylase inhibitors for the treatment of ocular neovascular or edematous disorders and diseases
|
US9006267B2
(en)
*
|
2002-11-14 |
2015-04-14 |
Celgene Corporation |
Pharmaceutical compositions and dosage forms of thalidomide
|
US7230012B2
(en)
|
2002-11-14 |
2007-06-12 |
Celgene Corporation |
Pharmaceutical compositions and dosage forms of thalidomide
|
US8431396B2
(en)
|
2003-03-21 |
2013-04-30 |
The Cleveland Clinic Foundation |
Anti-angiogenic peptides
|
US7517887B2
(en)
*
|
2003-04-09 |
2009-04-14 |
General Atomics |
Reversible inhibitors of S-adenosyl-L-homocysteine hydrolase and uses thereof
|
US7868011B2
(en)
*
|
2003-04-09 |
2011-01-11 |
General Atomics |
Use of reversible inhibitors of S-adenosyl-L-homocysteine hydrolase for treating lupus
|
US7196093B2
(en)
*
|
2003-04-09 |
2007-03-27 |
General Atomics |
Reversible inhibitors of SAH hydrolase and uses thereof
|
DE10323898A1
(de)
|
2003-05-26 |
2004-12-23 |
Wilex Ag |
Hydroxyamidin- und Hydroxyguanidin-Verbindungen als Urokinase-Hemmstoffe
|
WO2005030120A2
(en)
*
|
2003-05-28 |
2005-04-07 |
Entremed, Inc. |
Antiangiogenic agents
|
WO2005016326A2
(en)
*
|
2003-07-11 |
2005-02-24 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Analogs of thalidomide as potential angiogenesis inhibitors
|
TW201319088A
(zh)
|
2003-07-18 |
2013-05-16 |
Amgen Inc |
對肝細胞生長因子具專一性之結合劑
|
UA83504C2
(en)
|
2003-09-04 |
2008-07-25 |
Селджин Корпорейшн |
Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione
|
JP4943845B2
(ja)
*
|
2003-09-17 |
2012-05-30 |
ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンティッド バイ ザ セクレタリー オブ ザ デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
サリドマイド類似体
|
US8952895B2
(en)
|
2011-06-03 |
2015-02-10 |
Apple Inc. |
Motion-based device operations
|
US20080027113A1
(en)
*
|
2003-09-23 |
2008-01-31 |
Zeldis Jerome B |
Methods of Using and Compositions Comprising Immunomodulatory Compounds for Treatment and Management of Macular Degeneration
|
US7612096B2
(en)
*
|
2003-10-23 |
2009-11-03 |
Celgene Corporation |
Methods for treatment, modification and management of radiculopathy using 1-oxo-2-(2,6-dioxopiperidin-3yl)-4-aminoisoindoline
|
WO2005046686A1
(en)
*
|
2003-11-06 |
2005-05-26 |
Celgene Corporation |
Methods and compositions using thalidomide for the treatment and management of cancers and other diseases
|
US20050100529A1
(en)
*
|
2003-11-06 |
2005-05-12 |
Zeldis Jerome B. |
Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of asbestos-related diseases and disorders
|
US20070208057A1
(en)
*
|
2003-11-06 |
2007-09-06 |
Zeldis Jerome B |
Methods And Compositions Using Thalidomide For The Treatment And Management Of Cancers And Other Diseases
|
CN101966183A
(zh)
*
|
2003-12-02 |
2011-02-09 |
细胞基因公司 |
用于治疗和控制血红蛋白病和贫血病的方法和组合物
|
US20050143344A1
(en)
*
|
2003-12-30 |
2005-06-30 |
Zeldis Jerome B. |
Methods and compositions using immunomodulatory compounds for the treatment and management of central nervous system disorders or diseases
|
US7430276B2
(en)
*
|
2004-02-25 |
2008-09-30 |
Nanodynamics-88 |
Low dose X-ray mammography method
|
WO2005089256A2
(en)
*
|
2004-03-12 |
2005-09-29 |
Entremed, Inc. |
Antiangiogenic agents
|
EP1737453A4
(de)
*
|
2004-03-22 |
2008-11-26 |
Celgene Corp |
Verfahren zur verwendung immunmodulatorischer verbindungen und diese enthaltende zusammensetzungen zur behandlung und versorgung von hautkrankheiten oder störungen
|
US20050222209A1
(en)
*
|
2004-04-01 |
2005-10-06 |
Zeldis Jerome B |
Methods and compositions for the treatment, prevention or management of dysfunctional sleep and dysfunctional sleep associated with disease
|
EA014429B1
(ru)
*
|
2004-04-14 |
2010-12-30 |
Селджин Корпорейшн |
Композиции, содержащие иммуномодулирующие соединения для лечения и управления течением миелодиспластических синдромов, и способы с их использованием
|
JP2007532642A
(ja)
*
|
2004-04-14 |
2007-11-15 |
セルジーン・コーポレーション |
脊髄形成異常症候群の治療及び管理のための選択的サイトカイン阻害薬の使用法、及びそれを含む組成物
|
JP2007533761A
(ja)
*
|
2004-04-23 |
2007-11-22 |
セルジーン・コーポレーション |
肺高血圧症を治療し管理するための、免疫調節性化合物の使用方法及び免疫調節性化合物を含む組成物
|
BRPI0510167A
(pt)
*
|
2004-04-23 |
2007-10-02 |
Celgene Corp |
método para tratar, prevenir ou controlar hipertensão pulmonar
|
SI1949915T1
(sl)
*
|
2004-04-30 |
2012-12-31 |
Biopheresis Technologies, Inc. |
Postopek in sistem za odstranitev topnih TNFR1, TNFR2 in IL2R pri pacientih
|
US7273890B1
(en)
*
|
2004-06-08 |
2007-09-25 |
Sagittarius Life Science Corp. |
ST104P, an anti-angiogenic agent
|
AU2005277203A1
(en)
*
|
2004-08-20 |
2006-03-02 |
Entremed, Inc. |
Compositions and methods comprising proteinase activated receptor antagonists
|
BRPI0514865A
(pt)
*
|
2004-09-03 |
2008-06-24 |
Celgene Corp |
processo para preparar um composto
|
KR20070085454A
(ko)
*
|
2004-10-28 |
2007-08-27 |
셀진 코포레이션 |
중추신경계 손상의 치료 및 관리를 위하여 pde4조절제를 사용하는 방법 및 조성물
|
AU2005309733A1
(en)
*
|
2004-11-23 |
2006-06-01 |
Celgene Corporation |
Methods and compositions using immunomodulatory compounds for treatment and management of central nervous system injury
|
KR101429774B1
(ko)
|
2005-05-09 |
2014-10-02 |
바이오스피어 메디칼 에스.에이. |
마이크로스피어 및 비이온성 조영제를 사용하는 조성물 및방법
|
US20060270707A1
(en)
*
|
2005-05-24 |
2006-11-30 |
Zeldis Jerome B |
Methods and compositions using 4-[(cyclopropanecarbonylamino)methyl]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione for the treatment or prevention of cutaneous lupus
|
US20080167272A1
(en)
*
|
2005-06-16 |
2008-07-10 |
Auckland Uniservices Limited |
Thalidomide metabolites and methods of use
|
CN102643267B
(zh)
*
|
2005-06-30 |
2015-09-16 |
细胞基因公司 |
4-氨基-2-(2,6-二氧哌啶-3-基)异吲哚啉-1,3-二酮化合物的制备方法
|
WO2007009001A1
(en)
*
|
2005-07-12 |
2007-01-18 |
The Regents Of The University Of California |
Use of cis-epoxyeicosatrienoic acids and inhibitors of soluble epoxide hydrolase to alleviate eye disorders
|
US20080138295A1
(en)
*
|
2005-09-12 |
2008-06-12 |
Celgene Coporation |
Bechet's disease using cyclopropyl-N-carboxamide
|
US20070065514A1
(en)
*
|
2005-09-22 |
2007-03-22 |
Howell Mark D |
Method for enhancing immune responses in mammals
|
CN1939922B
(zh)
*
|
2005-09-27 |
2010-10-13 |
天津和美生物技术有限公司 |
可抑制细胞释放肿瘤坏死因子的5H-噻吩[3,4-c]吡咯-4,6-二酮衍生物
|
KR20080055914A
(ko)
*
|
2005-10-14 |
2008-06-19 |
에프. 호프만-라 로슈 아게 |
5-(2-클로로페닐)-1,2-디히드로-7-플루오로-8-메톡시-3-메틸-피라졸로[3,4-b][1,4] 벤조디아제핀의 투여 섭생
|
US20070155791A1
(en)
*
|
2005-12-29 |
2007-07-05 |
Zeldis Jerome B |
Methods for treating cutaneous lupus using aminoisoindoline compounds
|
WO2007090127A2
(en)
|
2006-01-30 |
2007-08-09 |
Surgica Corporation |
Compressible intravascular embolization particles and related methods and delivery systems
|
WO2007090130A2
(en)
*
|
2006-01-30 |
2007-08-09 |
Surgica Corporation |
Porous intravascular embolization particles and related methods
|
US8399440B2
(en)
*
|
2006-03-20 |
2013-03-19 |
Entremed, Inc. |
Disease modifying anti-arthritic activity of 2-methoxyestradiol
|
US20070226632A1
(en)
*
|
2006-03-21 |
2007-09-27 |
Nokia Corporation |
Method, electronic device and computer program product for enhancing contact list functionality
|
AU2007238785B2
(en)
*
|
2006-04-13 |
2013-02-07 |
Agnieszka Ambrozak |
Tetrahalogenated compounds useful as inhibitors of angiogenesis
|
WO2007136640A2
(en)
*
|
2006-05-16 |
2007-11-29 |
Celgene Corporation |
Processes for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
|
US20080051431A1
(en)
*
|
2006-05-26 |
2008-02-28 |
Dominique Verhelle |
Methods and compositions using immunomodulatory compounds in combination therapy
|
AU2007267928A1
(en)
*
|
2006-05-26 |
2007-12-06 |
Celgene Corporation |
Methods and compositions using immunomodulatory compounds in combination therapy
|
WO2008007979A1
(en)
*
|
2006-07-12 |
2008-01-17 |
Auckland Uniservices Limited |
(2,6-dioxo-3-piperinyl)amidobenzoic immunomodulatory and anti-cancer derivatives
|
PE20080403A1
(es)
|
2006-07-14 |
2008-04-25 |
Amgen Inc |
Derivados heterociclicos fusionados y metodos de uso
|
US8217177B2
(en)
|
2006-07-14 |
2012-07-10 |
Amgen Inc. |
Fused heterocyclic derivatives and methods of use
|
WO2008011513A2
(en)
|
2006-07-19 |
2008-01-24 |
The Cleveland Clinic Foundation |
Compounds and methods of modulating angiogenesis
|
CL2007002218A1
(es)
*
|
2006-08-03 |
2008-03-14 |
Celgene Corp Soc Organizada Ba |
Uso de 3-(4-amino-1-oxo-1,3-dihidro-isoindol-2-il)-piperidina 2,6-diona para la preparacion de un medicamento util para el tratamiento de linfoma de celula de capa.
|
CN101138634A
(zh)
*
|
2006-09-07 |
2008-03-12 |
于保法 |
用于治疗肿瘤的组合物
|
US20080075690A1
(en)
*
|
2006-09-22 |
2008-03-27 |
Mark Douglas Howell |
Method for enhancing immune responses in mammals
|
CA2676173A1
(en)
|
2007-02-16 |
2008-08-28 |
Amgen Inc. |
Nitrogen-containing heterocyclyl ketones and their use as c-met inhibitors
|
EP2146690B1
(de)
*
|
2007-04-13 |
2018-03-21 |
Teva Pharmaceuticals International GmbH |
Orale dosierungsformungen von cephalotaxin
|
US7893045B2
(en)
|
2007-08-07 |
2011-02-22 |
Celgene Corporation |
Methods for treating lymphomas in certain patient populations and screening patients for said therapy
|
SG10201500328QA
(en)
|
2007-08-21 |
2015-03-30 |
Amgen Inc |
Human c-fms antigen binding proteins
|
EP2207570A2
(de)
|
2007-09-14 |
2010-07-21 |
Nitto Denko Corporation |
Arzneimittelträger
|
US11331294B2
(en)
|
2007-09-26 |
2022-05-17 |
Indiana University Research And Technology Corporation |
Benzoquinone derivative E3330 in combination with chemotherapeutic agents for the treatment of bladder cancer
|
CA2700274C
(en)
*
|
2007-09-26 |
2017-08-22 |
Indiana University Research And Technology Corporation |
Quinone derivatives, pharmaceutical compositions, and uses thereof
|
NZ586053A
(en)
|
2007-11-09 |
2012-09-28 |
Peregrine Pharmaceuticals Inc |
Anti-vegf antibody compositions and methods
|
US20090137631A1
(en)
*
|
2007-11-22 |
2009-05-28 |
National Yang-Ming University |
Methods and pharmaceutical compositions for regulation of g- and/or gc-rich nucleic acid expression
|
CA2729303A1
(en)
|
2008-06-30 |
2010-01-14 |
Angioblast Systems, Inc. |
Treatment of eye diseases and excessive neovascularization using a combined therapy
|
AU2009274512A1
(en)
|
2008-07-25 |
2010-01-28 |
The Regents Of The University Of Colorado |
Clip inhibitors and methods of modulating immune function
|
US20110212179A1
(en)
*
|
2008-10-30 |
2011-09-01 |
David Liu |
Micro-spherical porous biocompatible scaffolds and methods and apparatus for fabricating same
|
SI3351240T1
(sl)
|
2009-05-19 |
2019-08-30 |
Celgene Corporation |
Formulacije 4-amino-2-(2,6-dioksopiperidin-3-il)izoindolin-1,3-diona
|
WO2010137547A1
(ja)
|
2009-05-25 |
2010-12-02 |
国立大学法人東京工業大学 |
中枢神経細胞の増殖及び分化に係る中核因子を含む医薬組成物
|
GB0914330D0
(en)
|
2009-08-17 |
2009-09-30 |
Univ Dublin City |
A method of predicting response to thalidomide in multiple myeloma patients
|
US20120183546A1
(en)
|
2009-09-23 |
2012-07-19 |
Amgen Inc. |
Treatment of ovarian cancer using a specific binding agent of human angiopoietin-2 in combination with a taxane
|
WO2012078492A1
(en)
|
2010-12-06 |
2012-06-14 |
Celgene Corporation |
A combination therapy with lenalidomide and a cdk inhibitor for treating multiple myeloma
|
WO2012079088A2
(en)
|
2010-12-10 |
2012-06-14 |
The Johns Hopkins University |
Mimetic peptides derived from collagen type iv and their use for treating angiogenesis- and lymphangiogenesis- dependent diseases
|
ES2543569T3
(es)
|
2011-03-23 |
2015-08-20 |
Amgen Inc. |
Inhibidores duales tricíclicos condensados de CDK 4/6 y FLT3
|
KR20140024914A
(ko)
|
2011-04-29 |
2014-03-03 |
셀진 코포레이션 |
예측인자로 세레브론을 사용하는 암 및 염증성 질환의 치료를 위한 방법
|
MX358726B
(es)
|
2011-06-29 |
2018-09-03 |
Amgen Inc |
Biomarcador predictivo de supervivencia en el tratamiento de carcinoma de celulas renales.
|
WO2013025939A2
(en)
|
2011-08-16 |
2013-02-21 |
Indiana University Research And Technology Corporation |
Compounds and methods for treating cancer by inhibiting the urokinase receptor
|
US20130058926A1
(en)
*
|
2011-08-30 |
2013-03-07 |
Shiseido Company, Ltd. |
Method for alleviating and/or preventing skin reddening
|
US8927725B2
(en)
|
2011-12-02 |
2015-01-06 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Thio compounds
|
WO2013126394A1
(en)
|
2012-02-21 |
2013-08-29 |
Celgene Corporation |
Solid forms of 3-(4-nitro-1-oxoisoindolin-2-yl)piperidine-2,6-dione
|
AR090263A1
(es)
|
2012-03-08 |
2014-10-29 |
Hoffmann La Roche |
Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma
|
JP6318152B2
(ja)
*
|
2012-06-29 |
2018-04-25 |
セルジーン コーポレイション |
セレブロン関連タンパク質を利用して薬物効能を決定する方法
|
US9587281B2
(en)
|
2012-08-14 |
2017-03-07 |
Celgene Corporation |
Cereblon isoforms and their use as biomarkers for therapeutic treatment
|
AU2013204922B2
(en)
|
2012-12-20 |
2015-05-14 |
Celgene Corporation |
Chimeric antigen receptors
|
CA2900529A1
(en)
|
2013-02-08 |
2014-08-14 |
Institute For Myeloma & Bone Cancer Research |
Improved diagnostic, prognostic, and monitoring methods for multiple myeloma, chronic lymphocytic leukemia, and b-cell non-hodgkin lymphoma
|
AU2014217485B2
(en)
|
2013-02-13 |
2017-02-16 |
Cartiheal (2009) Ltd |
Solid substrates for mitigating or preventing cell and tissue adhesion and vascularization
|
CN105518018B
(zh)
|
2013-03-15 |
2020-04-03 |
细胞基因公司 |
修饰的t淋巴细胞
|
EP2815749A1
(de)
|
2013-06-20 |
2014-12-24 |
IP Gesellschaft für Management mbH |
Feste Form von 4-Amino-2-(2,6-dioxopiperidin-3-yl)isoindolin-1,3-dion mit spezifischem Röntgenbeugungsspektrum
|
US9198898B2
(en)
|
2013-06-24 |
2015-12-01 |
Tigercat Pharma, Inc. |
Use of NK-1 receptor antagonists in pruritus
|
US8906951B1
(en)
|
2013-06-24 |
2014-12-09 |
Tigercat Pharma, Inc. |
Use of NK-1 receptor antagonists in pruritus
|
AU2015210999A1
(en)
|
2014-01-29 |
2016-07-21 |
Otsuka Pharmaceutical Co., Ltd. |
Device-based risk management of a therapeutic
|
EP3148545B1
(de)
|
2014-05-28 |
2023-03-15 |
Onco Tracker, Inc. |
Anti-krebs-wirkung von jak2-inhibitoren in kombination mit thalidomidderivaten und glucocorticoiden
|
EP3160486B1
(de)
|
2014-06-27 |
2020-11-18 |
Celgene Corporation |
Zusammensetzungen und verfahren zur induktion von konformationsänderungen bei cereblon und anderen e3-ubiquitin-ligasen
|
PL3182996T3
(pl)
|
2014-08-22 |
2023-04-17 |
Celgene Corporation |
Sposoby leczenia szpiczaka mnogiego związkami immunomodulującymi w kombinacji z przeciwciałami
|
US10017492B2
(en)
|
2014-10-30 |
2018-07-10 |
Kangpu Biopharmaceuticals, Ltd. |
Isoindoline derivative, intermediate, preparation method, pharmaceutical composition and use thereof
|
CA2968853A1
(en)
|
2014-11-26 |
2016-06-02 |
Baofa Yu |
Hapten-enhanced chemoimmunotherapy by ultra-minimum incision personalized intratumoral chemoimmunotherapy
|
WO2016209972A1
(en)
|
2015-06-26 |
2016-12-29 |
Amgen Inc. |
Biomarker of survival in the treatment of renal cell carcinoma with a vegfr inhibitor and an ang2 inhibitor
|
WO2016210262A1
(en)
|
2015-06-26 |
2016-12-29 |
Celgene Corporation |
Methods for the treatment of kaposi's sarcoma or kshv-induced lymphoma using immunomodulatory compounds, and uses of biomarkers
|
BR112018001480A2
(pt)
|
2015-07-24 |
2018-09-11 |
Oncotracker Inc |
moduladores de gama secretase para o tratamento de disfunção do sistema imunológico
|
AU2016330967B2
(en)
*
|
2015-09-30 |
2021-03-25 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Thalidomide analogs and methods of use
|
AU2016341520C1
(en)
|
2015-10-21 |
2021-07-22 |
Otsuka Pharmaceutical Co., Ltd. |
Benzolactam compounds as protein kinase inhibitors
|
WO2017117118A1
(en)
|
2015-12-28 |
2017-07-06 |
Celgene Corporation |
Compositions and methods for inducing conformational changes in cereblon and other e3 ubiquitin ligases
|
US11698369B2
(en)
|
2016-01-12 |
2023-07-11 |
Oncotracker, Inc. |
Methods for monitoring immune status of a subject
|
IL305200A
(en)
*
|
2016-03-31 |
2023-10-01 |
Omeros Corp |
MASP-2 suppressing agents for use in suppressing angiogenesis
|
CN110248678A
(zh)
|
2016-12-03 |
2019-09-17 |
朱诺治疗学股份有限公司 |
调节car-t细胞的方法
|
US20200078400A1
(en)
|
2016-12-03 |
2020-03-12 |
Juno Therapeutics, Inc. |
Methods for determining car-t cells dosing
|
ES2894255T3
(es)
|
2016-12-22 |
2022-02-14 |
Amgen Inc |
Derivados de benzoisotiazol, isotiazolo[3,4-b]piridina, quinazolina, ftalazina, pirido[2,3-d]piridazina y derivados de pirido[2,3-d]pirimidina como inhibidores de KRAS G12C para tratar el cáncer de pulmón, pancreático o colorrectal
|
US10786471B2
(en)
|
2017-02-06 |
2020-09-29 |
Massachusetts Institute Of Technology |
Methods and products related to glutaminase inhibitors
|
GB201706327D0
(en)
|
2017-04-20 |
2017-06-07 |
Otsuka Pharma Co Ltd |
A pharmaceutical compound
|
WO2018204427A1
(en)
|
2017-05-01 |
2018-11-08 |
Juno Therapeutics, Inc. |
Combination of a cell therapy and an immunomodulatory compound
|
JOP20190272A1
(ar)
|
2017-05-22 |
2019-11-21 |
Amgen Inc |
مثبطات kras g12c وطرق لاستخدامها
|
US10093647B1
(en)
|
2017-05-26 |
2018-10-09 |
Celgene Corporation |
Crystalline 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione dihydrate, compositions and methods of use thereof
|
JP2020522489A
(ja)
|
2017-06-02 |
2020-07-30 |
ジュノー セラピューティクス インコーポレイテッド |
養子細胞療法を用いる処置のための製造物品および方法
|
US11635435B2
(en)
|
2017-06-13 |
2023-04-25 |
Oncotracker, Inc. |
Diagnostic, prognostic, and monitoring methods for solid tumor cancers
|
AU2018291032A1
(en)
|
2017-06-29 |
2020-01-16 |
Juno Therapeutics, Inc. |
Mouse model for assessing toxicities associated with immunotherapies
|
US10513515B2
(en)
|
2017-08-25 |
2019-12-24 |
Biotheryx, Inc. |
Ether compounds and uses thereof
|
SG11202001499WA
(en)
|
2017-09-08 |
2020-03-30 |
Amgen Inc |
Inhibitors of kras g12c and methods of using the same
|
US10093648B1
(en)
|
2017-09-22 |
2018-10-09 |
Celgene Corporation |
Crystalline 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione hemihydrate, compositions and methods of use thereof
|
US10093649B1
(en)
|
2017-09-22 |
2018-10-09 |
Celgene Corporation |
Crystalline 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione monohydrate, compositions and methods of use thereof
|
EP3703688A2
(de)
|
2017-11-01 |
2020-09-09 |
Juno Therapeutics, Inc. |
Antikörper und chimäre antigen-rezeptoren, die spezifisch für b-zell-reifungsantigen sind
|
US20210132042A1
(en)
|
2017-11-01 |
2021-05-06 |
Juno Therapeutics, Inc. |
Methods of assessing or monitoring a response to a cell therapy
|
MA51210A
(fr)
|
2017-12-01 |
2020-10-07 |
Juno Therapeutics Inc |
Procédés de dosage et de modulation de cellules génétiquement modifiées
|
MA51184A
(fr)
|
2017-12-15 |
2020-10-21 |
Juno Therapeutics Inc |
Molécules de liaison à l'anti-cct5 et procédés d'utilisation associés
|
US10537585B2
(en)
|
2017-12-18 |
2020-01-21 |
Dexcel Pharma Technologies Ltd. |
Compositions comprising dexamethasone
|
WO2019210080A1
(en)
*
|
2018-04-25 |
2019-10-31 |
The Regents Of The University Of California |
Methods and compositions for skeletal and neurological disorders
|
EP3788053A1
(de)
|
2018-05-04 |
2021-03-10 |
Amgen Inc. |
Kras-g12c-inhibitoren und verfahren zu deren verwendung
|
WO2019213516A1
(en)
|
2018-05-04 |
2019-11-07 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
MA52564A
(fr)
|
2018-05-10 |
2021-03-17 |
Amgen Inc |
Inhibiteurs de kras g12c pour le traitement du cancer
|
AU2019278998B2
(en)
|
2018-06-01 |
2023-11-09 |
Amgen Inc. |
KRAS G12C inhibitors and methods of using the same
|
AU2019284472A1
(en)
|
2018-06-11 |
2020-11-26 |
Amgen Inc. |
KRAS G12C inhibitors for treating cancer
|
EP3807276A2
(de)
|
2018-06-12 |
2021-04-21 |
Amgen Inc. |
Einen piperazinring umfassende kras g12c-inhibitoren und ihre verwendung zur krebsbehandlung
|
CA3106239A1
(en)
|
2018-07-27 |
2020-01-30 |
Biotheryx, Inc. |
Bifunctional compounds as cdk modulators
|
JP2022512971A
(ja)
|
2018-11-08 |
2022-02-07 |
ジュノー セラピューティクス インコーポレイテッド |
処置およびt細胞調節のための方法および併用
|
MX2021005734A
(es)
|
2018-11-16 |
2021-09-10 |
Juno Therapeutics Inc |
Metodos de dosificacion de celulas t modificadas para el tratamiento de malignidades de celulas b.
|
JP2020090482A
(ja)
|
2018-11-16 |
2020-06-11 |
アムジエン・インコーポレーテツド |
Kras g12c阻害剤化合物の重要な中間体の改良合成法
|
JP7377679B2
(ja)
|
2018-11-19 |
2023-11-10 |
アムジエン・インコーポレーテツド |
がん治療のためのkrasg12c阻害剤及び1種以上の薬学的に活性な追加の薬剤を含む併用療法
|
EP3883565A1
(de)
|
2018-11-19 |
2021-09-29 |
Amgen Inc. |
Kras-g12c-inhibitoren und verfahren zu deren verwendung
|
WO2020113194A2
(en)
|
2018-11-30 |
2020-06-04 |
Juno Therapeutics, Inc. |
Methods for treatment using adoptive cell therapy
|
WO2020132651A1
(en)
|
2018-12-20 |
2020-06-25 |
Amgen Inc. |
Kif18a inhibitors
|
AU2019404576A1
(en)
|
2018-12-20 |
2021-06-24 |
Amgen Inc. |
Heteroaryl amides useful as KIF18A inhibitors
|
JP7407196B2
(ja)
|
2018-12-20 |
2023-12-28 |
アムジエン・インコーポレーテツド |
Kif18a阻害剤
|
JP2022513971A
(ja)
|
2018-12-20 |
2022-02-09 |
アムジエン・インコーポレーテツド |
Kif18a阻害剤として有用なヘテロアリールアミド
|
EP3917570A1
(de)
|
2019-01-29 |
2021-12-08 |
Juno Therapeutics, Inc. |
Antikörper und chimäre antigen-rezeptoren spezifisch für rezeptortyrosinkinase-like orphanrezeptor 1 (ror1)
|
US20230148450A9
(en)
|
2019-03-01 |
2023-05-11 |
Revolution Medicines, Inc. |
Bicyclic heteroaryl compounds and uses thereof
|
SG11202109422WA
(en)
|
2019-03-01 |
2021-09-29 |
Revolution Medicines Inc |
Bicyclic heterocyclyl compounds and uses thereof
|
EP3738593A1
(de)
|
2019-05-14 |
2020-11-18 |
Amgen, Inc |
Dosierung von kras-inhibitor zur behandlung von krebserkrankungen
|
AU2020280024A1
(en)
|
2019-05-21 |
2021-12-09 |
Amgen Inc. |
Solid state forms
|
EP4007756A1
(de)
|
2019-08-02 |
2022-06-08 |
Amgen Inc. |
Kif18a-inhibitoren
|
AU2020326627A1
(en)
|
2019-08-02 |
2022-03-17 |
Amgen Inc. |
KIF18A inhibitors
|
MX2022001302A
(es)
|
2019-08-02 |
2022-03-02 |
Amgen Inc |
Inhibidores de kif18a.
|
CA3155857A1
(en)
|
2019-10-24 |
2021-04-29 |
Amgen Inc. |
PYRIDOPYRIMIDINE DERIVATIVES USEFUL AS KRAS G12C AND KRAS G12D INHIBITORS IN THE TREATMENT OF CANCER
|
AU2020377925A1
(en)
|
2019-11-04 |
2022-05-05 |
Revolution Medicines, Inc. |
Ras inhibitors
|
BR112022008534A2
(pt)
|
2019-11-04 |
2022-08-09 |
Revolution Medicines Inc |
Compostos, composição farmacêutica, conjugado e métodos para tratar câncer e para tratar um distúrbio relacionado à proteína ras
|
CN116425742A
(zh)
|
2019-11-08 |
2023-07-14 |
锐新医药公司 |
双环杂芳基化合物及其用途
|
EP4058432A1
(de)
|
2019-11-14 |
2022-09-21 |
Amgen Inc. |
Verbesserte synthese einer kras-g12c-hemmenden verbindung
|
AR120457A1
(es)
|
2019-11-14 |
2022-02-16 |
Amgen Inc |
Síntesis mejorada del compuesto inhibidor de g12c de kras
|
JP2023505100A
(ja)
|
2019-11-27 |
2023-02-08 |
レボリューション メディシンズ インコーポレイテッド |
共有ras阻害剤及びその使用
|
CN114929279A
(zh)
|
2020-01-07 |
2022-08-19 |
锐新医药公司 |
Shp2抑制剂给药和治疗癌症的方法
|
US11897930B2
(en)
|
2020-04-28 |
2024-02-13 |
Anwita Biosciences, Inc. |
Interleukin-2 polypeptides and fusion proteins thereof, and their pharmaceutical compositions and therapeutic applications
|
MX2022016355A
(es)
|
2020-06-18 |
2023-04-03 |
Revolution Medicines Inc |
Metodos para retardar, prevenir, y tratar la resistencia adquirida a inhibidores de ras.
|
AU2021344830A1
(en)
|
2020-09-03 |
2023-04-06 |
Revolution Medicines, Inc. |
Use of SOS1 inhibitors to treat malignancies with SHP2 mutations
|
WO2022060836A1
(en)
|
2020-09-15 |
2022-03-24 |
Revolution Medicines, Inc. |
Indole derivatives as ras inhibitors in the treatment of cancer
|
CA3203111A1
(en)
|
2020-12-22 |
2022-06-30 |
Kailiang Wang |
Sos1 inhibitors and uses thereof
|
EP4334324A1
(de)
|
2021-05-05 |
2024-03-13 |
Revolution Medicines, Inc. |
Kovalente ras-inhibitoren und verwendungen davon
|
KR20240004960A
(ko)
|
2021-05-05 |
2024-01-11 |
레볼루션 메디슨즈, 인크. |
Ras 억제제
|
PE20240089A1
(es)
|
2021-05-05 |
2024-01-16 |
Revolution Medicines Inc |
Inhibidores de ras para el tratamiento del cancer
|
AR127308A1
(es)
|
2021-10-08 |
2024-01-10 |
Revolution Medicines Inc |
Inhibidores ras
|
EP4227307A1
(de)
|
2022-02-11 |
2023-08-16 |
Genzyme Corporation |
Pyrazolopyrazinverbindungen als shp2-inhibitoren
|
WO2023172940A1
(en)
|
2022-03-08 |
2023-09-14 |
Revolution Medicines, Inc. |
Methods for treating immune refractory lung cancer
|
WO2023240263A1
(en)
|
2022-06-10 |
2023-12-14 |
Revolution Medicines, Inc. |
Macrocyclic ras inhibitors
|
WO2023250400A1
(en)
|
2022-06-22 |
2023-12-28 |
Juno Therapeutics, Inc. |
Treatment methods for second line therapy of cd19-targeted car t cells
|
WO2024081916A1
(en)
|
2022-10-14 |
2024-04-18 |
Black Diamond Therapeutics, Inc. |
Methods of treating cancers using isoquinoline or 6-aza-quinoline derivatives
|