DE69505986D1 - Vorrichtung zum chemischen mischen und reagieren - Google Patents
Vorrichtung zum chemischen mischen und reagierenInfo
- Publication number
- DE69505986D1 DE69505986D1 DE69505986T DE69505986T DE69505986D1 DE 69505986 D1 DE69505986 D1 DE 69505986D1 DE 69505986 T DE69505986 T DE 69505986T DE 69505986 T DE69505986 T DE 69505986T DE 69505986 D1 DE69505986 D1 DE 69505986D1
- Authority
- DE
- Germany
- Prior art keywords
- chemicals
- laminae
- chemical
- outlet ports
- inlet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000126 substance Substances 0.000 title abstract 6
- 238000000034 method Methods 0.000 abstract 2
- 238000012993 chemical processing Methods 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000000737 periodic effect Effects 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/421—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path
- B01F25/422—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path between stacked plates, e.g. grooved or perforated plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/08—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
- B01J19/12—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor employing electromagnetic waves
- B01J19/122—Incoherent waves
- B01J19/123—Ultra-violet light
-
- B01J35/56—
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00783—Laminate assemblies, i.e. the reactor comprising a stack of plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00819—Materials of construction
- B01J2219/00822—Metal
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00819—Materials of construction
- B01J2219/00824—Ceramic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00819—Materials of construction
- B01J2219/00824—Ceramic
- B01J2219/00828—Silicon wafers or plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00819—Materials of construction
- B01J2219/00831—Glass
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00819—Materials of construction
- B01J2219/00833—Plastic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00889—Mixing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0887—Laminated structure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y80/00—Products made by additive manufacturing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S366/00—Agitating
- Y10S366/03—Micromixers: variable geometry from the pathway influences mixing/agitation of non-laminar fluid flow
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Electromagnetism (AREA)
- Toxicology (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/280,046 US5595712A (en) | 1994-07-25 | 1994-07-25 | Chemical mixing and reaction apparatus |
PCT/US1995/009834 WO1996003206A1 (en) | 1994-07-25 | 1995-07-20 | Chemical mixing and reaction apparatus and processes for the preparation thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69505986D1 true DE69505986D1 (de) | 1998-12-17 |
DE69505986T2 DE69505986T2 (de) | 1999-05-20 |
Family
ID=23071411
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69505986T Expired - Lifetime DE69505986T2 (de) | 1994-07-25 | 1995-07-20 | Vorrichtung zum chemischen mischen und reagieren |
Country Status (9)
Country | Link |
---|---|
US (1) | US5595712A (de) |
EP (1) | EP0772490B1 (de) |
JP (1) | JP3862749B2 (de) |
KR (1) | KR100361411B1 (de) |
AT (1) | ATE173181T1 (de) |
BR (1) | BR9508431A (de) |
DE (1) | DE69505986T2 (de) |
RU (1) | RU2149054C1 (de) |
WO (1) | WO1996003206A1 (de) |
Families Citing this family (138)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY110990A (en) * | 1993-06-03 | 1999-07-31 | Atomaer Pty Ltd | Multiphase staged passive reactor |
US5571410A (en) * | 1994-10-19 | 1996-11-05 | Hewlett Packard Company | Fully integrated miniaturized planar liquid sample handling and analysis device |
US5658537A (en) * | 1995-07-18 | 1997-08-19 | Basf Corporation | Plate-type chemical reactor |
US6063633A (en) | 1996-02-28 | 2000-05-16 | The University Of Houston | Catalyst testing process and apparatus |
US7244622B2 (en) | 1996-04-03 | 2007-07-17 | Applera Corporation | Device and method for multiple analyte detection |
US6825047B1 (en) | 1996-04-03 | 2004-11-30 | Applera Corporation | Device and method for multiple analyte detection |
JP4912517B2 (ja) * | 1996-04-03 | 2012-04-11 | アプライド バイオシステムズ リミテッド ライアビリティー カンパニー | 複数の分析物の検出のためのデバイスおよび方法 |
US7235406B1 (en) | 1996-04-03 | 2007-06-26 | Applera Corporation | Nucleic acid analysis device |
JPH1094723A (ja) * | 1996-09-20 | 1998-04-14 | Eiichi Sugiura | 気体混合液中の気体の微粒化装置 |
JP2001521622A (ja) * | 1997-04-04 | 2001-11-06 | カリパー テクノロジーズ コーポレイション | 閉ループ生化学分析器 |
US5993750A (en) * | 1997-04-11 | 1999-11-30 | Eastman Kodak Company | Integrated ceramic micro-chemical plant |
US5961932A (en) * | 1997-06-20 | 1999-10-05 | Eastman Kodak Company | Reaction chamber for an integrated micro-ceramic chemical plant |
US5842787A (en) | 1997-10-09 | 1998-12-01 | Caliper Technologies Corporation | Microfluidic systems incorporating varied channel dimensions |
AU1517999A (en) * | 1997-10-15 | 1999-05-03 | Aclara Biosciences, Inc. | Laminate microstructure device and method for making same |
DE19746583A1 (de) * | 1997-10-22 | 1999-04-29 | Merck Patent Gmbh | Mikromischer |
DE19746584A1 (de) * | 1997-10-22 | 1999-04-29 | Merck Patent Gmbh | Gehäuse für Mikromischer |
EP1054694A2 (de) | 1998-02-13 | 2000-11-29 | Selective Genetics, Inc. | Gleichzeitige strömungsdurchmischung zur herstellung von zusammensetzungen, die gentherapievektoren enthalten |
US6149882A (en) * | 1998-06-09 | 2000-11-21 | Symyx Technologies, Inc. | Parallel fixed bed reactor and fluid contacting apparatus |
US20050244954A1 (en) * | 1998-06-23 | 2005-11-03 | Blackburn Gary F | Binding acceleration techniques for the detection of analytes |
US6494614B1 (en) * | 1998-07-27 | 2002-12-17 | Battelle Memorial Institute | Laminated microchannel devices, mixing units and method of making same |
WO2000019193A1 (en) * | 1998-09-28 | 2000-04-06 | Varian Inc | Split flow electrospray device for mass spectrometry |
US6572830B1 (en) | 1998-10-09 | 2003-06-03 | Motorola, Inc. | Integrated multilayered microfludic devices and methods for making the same |
US6592696B1 (en) | 1998-10-09 | 2003-07-15 | Motorola, Inc. | Method for fabricating a multilayered structure and the structures formed by the method |
US7150994B2 (en) * | 1999-03-03 | 2006-12-19 | Symyx Technologies, Inc. | Parallel flow process optimization reactor |
FR2790684B1 (fr) * | 1999-03-09 | 2001-05-11 | Biomerieux Sa | Appareil permettant en son sein le transfert de liquides par capillarite |
US6942771B1 (en) * | 1999-04-21 | 2005-09-13 | Clinical Micro Sensors, Inc. | Microfluidic systems in the electrochemical detection of target analytes |
US20040053290A1 (en) * | 2000-01-11 | 2004-03-18 | Terbrueggen Robert Henry | Devices and methods for biochip multiplexing |
US20020177135A1 (en) * | 1999-07-27 | 2002-11-28 | Doung Hau H. | Devices and methods for biochip multiplexing |
DE19927554C2 (de) * | 1999-06-16 | 2002-12-19 | Inst Mikrotechnik Mainz Gmbh | Mikromischer |
DE19935433A1 (de) * | 1999-08-01 | 2001-03-01 | Febit Ferrarius Biotech Gmbh | Mikrofluidischer Reaktionsträger |
US6932951B1 (en) | 1999-10-29 | 2005-08-23 | Massachusetts Institute Of Technology | Microfabricated chemical reactor |
US20020112961A1 (en) * | 1999-12-02 | 2002-08-22 | Nanostream, Inc. | Multi-layer microfluidic device fabrication |
US7241423B2 (en) * | 2000-02-03 | 2007-07-10 | Cellular Process Chemistry, Inc. | Enhancing fluid flow in a stacked plate microreactor |
US7056477B1 (en) | 2000-02-03 | 2006-06-06 | Cellular Process Chemistry, Inc. | Modular chemical production system incorporating a microreactor |
US6537506B1 (en) | 2000-02-03 | 2003-03-25 | Cellular Process Chemistry, Inc. | Miniaturized reaction apparatus |
US7435392B2 (en) * | 2000-02-03 | 2008-10-14 | Acclavis, Llc | Scalable continuous production system |
ATE287291T1 (de) | 2000-03-07 | 2005-02-15 | Symyx Technologies Inc | Prozessoptimierungsreaktor mit parallelem durchfluss |
US7485454B1 (en) * | 2000-03-10 | 2009-02-03 | Bioprocessors Corp. | Microreactor |
US6561208B1 (en) | 2000-04-14 | 2003-05-13 | Nanostream, Inc. | Fluidic impedances in microfluidic system |
DE10025699A1 (de) * | 2000-05-23 | 2001-12-06 | Merck Patent Gmbh | Emulgier- und Trennvorrichtung für flüssige Phasen |
US7413714B1 (en) | 2000-07-16 | 2008-08-19 | Ymc Co. Ltd. | Sequential reaction system |
DE10036602A1 (de) * | 2000-07-27 | 2002-02-14 | Cpc Cellular Process Chemistry | Mikroreaktor für Reaktionen zwischen Gasen und Flüssigkeiten |
AU2001281076A1 (en) * | 2000-08-07 | 2002-02-18 | Nanostream, Inc. | Fluidic mixer in microfluidic system |
US6890093B2 (en) * | 2000-08-07 | 2005-05-10 | Nanostream, Inc. | Multi-stream microfludic mixers |
GB2372948A (en) * | 2000-10-31 | 2002-09-11 | Chart Heat Exchangers Ltd | A bonded stack of plates forming a heat exchanger and/or fluid mixing apparatus |
US6632014B2 (en) * | 2000-12-04 | 2003-10-14 | Yeda Research And Development Co., Ltd. | Device and method for mixing substances |
TWI241343B (en) * | 2000-12-07 | 2005-10-11 | Effector Cell Inst Inc | Well unit for detecting cell chemotaxis and separating chemotactic cells |
JP3738899B2 (ja) * | 2000-12-07 | 2006-01-25 | 株式会社 エフェクター細胞研究所 | 微量試料処理装置 |
US7101514B2 (en) | 2001-01-31 | 2006-09-05 | Po-Hao Adam Huang | Control devices for evaporative chemical mixing/reaction |
DE10106952C2 (de) * | 2001-02-15 | 2003-01-16 | Cognis Deutschland Gmbh | Chip-Reaktor |
US7118917B2 (en) | 2001-03-07 | 2006-10-10 | Symyx Technologies, Inc. | Parallel flow reactor having improved thermal control |
US20040058407A1 (en) * | 2001-04-10 | 2004-03-25 | Miller Scott E. | Reactor systems having a light-interacting component |
US20040132166A1 (en) * | 2001-04-10 | 2004-07-08 | Bioprocessors Corp. | Determination and/or control of reactor environmental conditions |
JP2004527247A (ja) * | 2001-04-10 | 2004-09-09 | バイオプロセッサーズ コーポレイション | 微小発酵器デバイスおよび細胞ベースのスクリーニング法 |
US20040058437A1 (en) * | 2001-04-10 | 2004-03-25 | Rodgers Seth T. | Materials and reactor systems having humidity and gas control |
US20050032204A1 (en) * | 2001-04-10 | 2005-02-10 | Bioprocessors Corp. | Microreactor architecture and methods |
US20050009101A1 (en) * | 2001-05-17 | 2005-01-13 | Motorola, Inc. | Microfluidic devices comprising biochannels |
JP3694877B2 (ja) * | 2001-05-28 | 2005-09-14 | 株式会社山武 | マイクロ混合器 |
US6919046B2 (en) * | 2001-06-07 | 2005-07-19 | Nanostream, Inc. | Microfluidic analytical devices and methods |
JP2005501711A (ja) * | 2001-06-27 | 2005-01-20 | エヌユー エレメント, インコーポレイテッド | 流体処理デバイス用モジュラーマイクロリアクタアーキテクチャおよび方法 |
US6939632B2 (en) * | 2001-08-06 | 2005-09-06 | Massachusetts Institute Of Technology | Thermally efficient micromachined device |
US20030029795A1 (en) * | 2001-08-07 | 2003-02-13 | Galik George M. | Apparatus and methods for dispersing one fluid in another fluid using a permeable body |
US20030175947A1 (en) * | 2001-11-05 | 2003-09-18 | Liu Robin Hui | Enhanced mixing in microfluidic devices |
US6877892B2 (en) * | 2002-01-11 | 2005-04-12 | Nanostream, Inc. | Multi-stream microfluidic aperture mixers |
US20050026134A1 (en) * | 2002-04-10 | 2005-02-03 | Bioprocessors Corp. | Systems and methods for control of pH and other reactor environment conditions |
AU2003235968A1 (en) * | 2002-04-30 | 2003-11-17 | Arkray, Inc. | Analytical instrument |
JP4855680B2 (ja) * | 2002-05-09 | 2012-01-18 | ザ・ユニバーシティ・オブ・シカゴ | 圧力駆動プラグによる輸送と反応のための装置および方法 |
TWI229931B (en) * | 2002-05-15 | 2005-03-21 | Amkor Technology Inc | Solder ball and conductive wire for a semiconductor package, and its manufacturing method, and its evaporation method |
US20040011650A1 (en) * | 2002-07-22 | 2004-01-22 | Frederic Zenhausern | Method and apparatus for manipulating polarizable analytes via dielectrophoresis |
EP1398077A1 (de) * | 2002-09-16 | 2004-03-17 | Corning Incorporated | Verfahren und Mikrofluidischereaktor für Photokatalyse |
GB2394912B (en) * | 2002-11-01 | 2006-07-12 | Norchip As | A microfabricated fluidic device for fragmentation |
DE20218972U1 (de) * | 2002-12-07 | 2003-02-13 | Ehrfeld Mikrotechnik Ag | Statischer Laminationsmikrovermischer |
CA2510166A1 (en) | 2002-12-20 | 2004-09-30 | Caliper Life Sciences, Inc. | Single molecule amplification and detection of dna |
TW200506364A (en) | 2003-04-09 | 2005-02-16 | Effector Cell Inst Inc | Apparatus for detecting cell chemo-taxis |
EP1618372A2 (de) * | 2003-04-14 | 2006-01-25 | Cellular Process Chemistry, Inc. | System und verfahren zur bestimmung der optimalen reaktionsparameter unter verwendung eines kontinuierlich laufenden prozesses |
US7442350B1 (en) * | 2003-04-17 | 2008-10-28 | Uop Llc | Plate design for mixer sparger |
JP4804718B2 (ja) * | 2003-04-28 | 2011-11-02 | 富士フイルム株式会社 | 流体混合装置、及び、流体混合システム |
US20040228211A1 (en) * | 2003-05-13 | 2004-11-18 | Koripella Chowdary R. | Internal micromixer |
US7435391B2 (en) * | 2003-05-23 | 2008-10-14 | Lucent Technologies Inc. | Light-mediated micro-chemical reactors |
US20050026273A1 (en) * | 2003-06-05 | 2005-02-03 | Zarur Andrey J. | Reactor with memory component |
JP4708342B2 (ja) | 2003-07-25 | 2011-06-22 | デックスコム・インコーポレーテッド | 埋設可能な装置に用いる酸素増大膜システム |
DE10333922B4 (de) * | 2003-07-25 | 2005-11-17 | Wella Ag | Bauteile für statische Mikromischer, daraus aufgebaute Mikromischer und deren Verwendung zum Mischen, zum Dispergieren oder zur Durchführung chemischer Reaktionen |
JP4559790B2 (ja) * | 2003-09-05 | 2010-10-13 | 大日本印刷株式会社 | 水素製造用のマイクロリアクターおよびその製造方法 |
JP4504751B2 (ja) * | 2003-10-07 | 2010-07-14 | 大日本印刷株式会社 | 水素製造用のマイクロリアクター |
US8066955B2 (en) * | 2003-10-17 | 2011-11-29 | James M. Pinchot | Processing apparatus fabrication |
US6994245B2 (en) * | 2003-10-17 | 2006-02-07 | James M. Pinchot | Micro-reactor fabrication |
US20050084072A1 (en) * | 2003-10-17 | 2005-04-21 | Jmp Industries, Inc., An Ohio Corporation | Collimator fabrication |
EP1525917A1 (de) * | 2003-10-23 | 2005-04-27 | F. Hoffmann-La Roche Ag | Mikrofluidische Vorrichtung mit Durchführung |
EP1526290A1 (de) * | 2003-10-23 | 2005-04-27 | F. Hoffmann-La Roche Ag | Mikrokanal mit Kapillarstoppventil |
US7080937B1 (en) * | 2003-11-13 | 2006-07-25 | Automatic Bar Controls, Inc. | Nonclogging static mixer |
US20070140042A1 (en) * | 2004-06-04 | 2007-06-21 | Gerhard Schanz | Multicomponent packaging with static micromixer |
EP1761331A2 (de) * | 2004-06-07 | 2007-03-14 | Bioprocessors Corporation | Steuerung von reaktorumgebungsbedingungen |
EP1765487A1 (de) * | 2004-06-07 | 2007-03-28 | Bioprocessors Corporation | Mischen im reaktor |
JP2008501365A (ja) * | 2004-06-07 | 2008-01-24 | バイオプロセッサーズ コーポレイション | 反応器における剪断力の生成 |
WO2005121307A2 (en) * | 2004-06-07 | 2005-12-22 | Bioprocessor Corp. | Gas control in a microreactor |
US7955504B1 (en) | 2004-10-06 | 2011-06-07 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Microfluidic devices, particularly filtration devices comprising polymeric membranes, and method for their manufacture and use |
US7391936B2 (en) * | 2005-01-21 | 2008-06-24 | Lucent Technologies, Inc. | Microfluidic sensors and methods for making the same |
WO2006110458A1 (en) * | 2005-04-08 | 2006-10-19 | Velocys, Inc. | Flow control through plural, parallel connecting channels to/from a manifold |
US20060272713A1 (en) * | 2005-05-31 | 2006-12-07 | Garner Sean M | Microfluidic devices with integrated tubular structures |
US20060285433A1 (en) * | 2005-06-20 | 2006-12-21 | Jing-Tang Yang | Fluidic mixer of serpentine channel incorporated with staggered sudden-expansion and convergent cross sections |
CA2618105A1 (en) * | 2005-08-11 | 2007-03-01 | Daniel M. Hartmann | Microfluidic reduction of diffusion and complience effect in a fluid mixing region |
FR2891911B1 (fr) * | 2005-10-07 | 2008-04-25 | Horiba Abx Sas Soc Par Actions | "dispositif modulaire destine a l'analyse d'un fluide biologique, notamment sanguin" |
US20090298139A1 (en) * | 2006-02-28 | 2009-12-03 | Jin Zou | Method for Polymer Synthesis Using Microfluidic Enzymatic Cascade |
TW200738328A (en) | 2006-03-31 | 2007-10-16 | Lonza Ag | Micro-reactor system assembly |
US20080108122A1 (en) * | 2006-09-01 | 2008-05-08 | State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon | Microchemical nanofactories |
WO2008052168A2 (en) * | 2006-10-26 | 2008-05-02 | Symyx Technologies, Inc. | High pressure parallel fixed bed reactor and method |
US20080153152A1 (en) * | 2006-11-22 | 2008-06-26 | Akira Wakabayashi | Microfluidic chip |
US8206025B2 (en) | 2007-08-07 | 2012-06-26 | International Business Machines Corporation | Microfluid mixer, methods of use and methods of manufacture thereof |
US20090211977A1 (en) * | 2008-02-27 | 2009-08-27 | Oregon State University | Through-plate microchannel transfer devices |
US8414182B2 (en) * | 2008-03-28 | 2013-04-09 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Micromixers for nanomaterial production |
US8430558B1 (en) * | 2008-09-05 | 2013-04-30 | University Of Central Florida Research Foundation, Inc. | Microfluidic mixer having channel width variation for enhanced fluid mixing |
US20100081577A1 (en) * | 2008-09-30 | 2010-04-01 | Symyx Technologies, Inc. | Reactor systems and methods |
BRPI1007625B1 (pt) * | 2009-04-23 | 2020-03-10 | Koninklijke Philips N.V. | Sistema microfluídico para misturar um fluido, cartucho, e método para misturar fluidos |
AU2010257118B2 (en) * | 2009-06-04 | 2014-08-28 | Lockheed Martin Corporation | Multiple-sample microfluidic chip for DNA analysis |
US8801922B2 (en) * | 2009-06-24 | 2014-08-12 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Dialysis system |
JP2012531256A (ja) * | 2009-06-24 | 2012-12-10 | ステイト オブ オレゴン アクティング バイ アンド スルー ザ ステイト ボード オブ ハイヤー エデュケーション オン ビハーフ オブ オレゴン ステイト ユニバーシティー | 透析用マイクロ流体デバイス |
JP2011050936A (ja) * | 2009-09-04 | 2011-03-17 | Nisso Engineering Co Ltd | 流通式管型反応装置 |
US20110189048A1 (en) * | 2009-12-05 | 2011-08-04 | Curtis James R | Modular dialysis system |
US8753515B2 (en) | 2009-12-05 | 2014-06-17 | Home Dialysis Plus, Ltd. | Dialysis system with ultrafiltration control |
WO2011084665A1 (en) | 2009-12-17 | 2011-07-14 | Actamax Surgical Materials Llc | Dispensing device having an array of laterally spaced tubes |
WO2011078790A1 (en) | 2009-12-23 | 2011-06-30 | Agency For Science, Technology And Research | Microfluidic mixing apparatus and method |
US8580161B2 (en) | 2010-05-04 | 2013-11-12 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Fluidic devices comprising photocontrollable units |
US8501009B2 (en) | 2010-06-07 | 2013-08-06 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Fluid purification system |
MX2013004184A (es) | 2010-10-15 | 2013-07-29 | Lockheed Corp | Diseño optico microfluidico. |
US9079140B2 (en) | 2011-04-13 | 2015-07-14 | Microfluidics International Corporation | Compact interaction chamber with multiple cross micro impinging jets |
ES2640953T3 (es) | 2011-10-07 | 2017-11-07 | Outset Medical, Inc. | Purificación de líquido de intercambio de calor para un sistema de diálisis |
US9322054B2 (en) | 2012-02-22 | 2016-04-26 | Lockheed Martin Corporation | Microfluidic cartridge |
KR101666425B1 (ko) * | 2013-11-25 | 2016-10-14 | 주식회사 엘지화학 | 미세 유로 반응기 |
ES2864727T3 (es) | 2014-04-29 | 2021-10-14 | Outset Medical Inc | Sistema y métodos de diálisis |
JP6310327B2 (ja) * | 2014-05-27 | 2018-04-11 | 株式会社エンプラス | 流体取扱装置 |
KR101647551B1 (ko) * | 2014-06-23 | 2016-08-23 | 경희대학교 산학협력단 | 미세입자 분리 장치 및 이를 이용한 분리 방법 |
US9943819B2 (en) | 2014-11-03 | 2018-04-17 | Singh Instrument LLC | Small-scale reactor having improved mixing |
EP3031518B1 (de) * | 2014-12-08 | 2021-01-20 | Lonza Ltd | Flüssigkeitsmischstruktur, einheit für kontinuierliche reaktion, reaktor für kontinuierliche reaktion und verfahren zur verwendung davon |
DE102015205543A1 (de) * | 2015-03-26 | 2016-09-29 | Robert Bosch Gmbh | Hydraulikblock für ein Hydroaggregat einer Bremsregelung einer hydraulischen Fahrzeugbremsanlage |
DE102015113432A1 (de) | 2015-08-14 | 2017-02-16 | Karlsruher Institut für Technologie | Strömungsleitelemente in einem Kanal |
JP7025408B2 (ja) | 2016-08-19 | 2022-02-24 | アウトセット・メディカル・インコーポレイテッド | 腹膜透析システム及び方法 |
WO2021031201A1 (zh) * | 2019-08-22 | 2021-02-25 | 于志远 | 一种微通道反应器及制备锂电池正极材料和负极材料的前驱体微纳米粒子的方法 |
DE202020107313U1 (de) | 2019-09-13 | 2021-02-12 | Hte Gmbh The High Throughput Experimentation Company | Vorrichtung zur Untersuchung von chemischen Prozessen |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1160401A (en) * | 1967-02-15 | 1969-08-06 | British Motor Corp Ltd | Mixing Liquids. |
NL6917131A (de) * | 1969-11-14 | 1971-05-18 | ||
US3881701A (en) * | 1973-09-17 | 1975-05-06 | Aerojet General Co | Fluid mixer reactor |
US3856270A (en) * | 1973-10-09 | 1974-12-24 | Fmc Corp | Static fluid mixing apparatus |
US4002289A (en) * | 1974-05-28 | 1977-01-11 | Moore Thomas B | Static-type mixer and receptacle |
US4222671A (en) * | 1978-09-05 | 1980-09-16 | Gilmore Oscar Patrick | Static mixer |
US4593446A (en) * | 1984-04-18 | 1986-06-10 | Hayner Paul F | Method of manufacturing a fluid flow restrictor |
JPS62108156A (ja) * | 1985-11-07 | 1987-05-19 | Sord Comput Corp | シリコン・ウエハ−キヤピラリイ・カラム |
FR2592320B1 (fr) * | 1985-12-30 | 1988-04-08 | Inst Francais Du Petrole | Nouveau procede d'oxydation d'une charge oxydable en phase gazeuse et reacteur pour la mise en oeuvre de ce procede. |
EP0285725B1 (de) * | 1987-04-10 | 1992-09-30 | Chugoku Kayaku Kabushiki Kaisha | Mischapparat |
US5252294A (en) * | 1988-06-01 | 1993-10-12 | Messerschmitt-Bolkow-Blohm Gmbh | Micromechanical structure |
FR2640620B1 (fr) * | 1988-12-20 | 1993-02-05 | Inst Francais Du Petrole | Procede de fabrication de pieces en materiau ceramique comportant des canaux calibres |
DE3926466C2 (de) * | 1989-08-10 | 1996-12-19 | Christoph Dipl Ing Caesar | Mikroreaktor zur Durchführung chemischer Reaktionen von zwei chemischen Stoffen mit starker Wärmetönung |
US5094788A (en) * | 1990-12-21 | 1992-03-10 | The Dow Chemical Company | Interfacial surface generator |
CH680788A5 (en) * | 1991-01-16 | 1992-11-13 | Alusuisse Lonza Services Ag | Filter or catalyst carrier - has structured flow channels and hollow zones for even exhaust gas flow without loss of pressure |
JP3025027B2 (ja) * | 1991-01-21 | 2000-03-27 | 株式会社日立製作所 | 酸素センサ |
DE69413012T2 (de) * | 1993-03-19 | 1999-03-25 | Du Pont | Integrierte vorrichtung für chemische verfahrensschritte und herstellungsverfahren dafür |
US5320139A (en) * | 1993-03-30 | 1994-06-14 | Millipore Corporation | Fluid delivery system |
-
1994
- 1994-07-25 US US08/280,046 patent/US5595712A/en not_active Expired - Lifetime
-
1995
- 1995-07-20 EP EP95928291A patent/EP0772490B1/de not_active Expired - Lifetime
- 1995-07-20 JP JP50599796A patent/JP3862749B2/ja not_active Expired - Fee Related
- 1995-07-20 RU RU97102694A patent/RU2149054C1/ru not_active IP Right Cessation
- 1995-07-20 AT AT95928291T patent/ATE173181T1/de not_active IP Right Cessation
- 1995-07-20 BR BR9508431A patent/BR9508431A/pt not_active IP Right Cessation
- 1995-07-20 KR KR1019970700480A patent/KR100361411B1/ko not_active IP Right Cessation
- 1995-07-20 DE DE69505986T patent/DE69505986T2/de not_active Expired - Lifetime
- 1995-07-20 WO PCT/US1995/009834 patent/WO1996003206A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
JPH10503708A (ja) | 1998-04-07 |
US5595712A (en) | 1997-01-21 |
JP3862749B2 (ja) | 2006-12-27 |
KR970704510A (ko) | 1997-09-06 |
BR9508431A (pt) | 1998-06-09 |
EP0772490A1 (de) | 1997-05-14 |
RU2149054C1 (ru) | 2000-05-20 |
KR100361411B1 (ko) | 2003-02-11 |
DE69505986T2 (de) | 1999-05-20 |
WO1996003206A1 (en) | 1996-02-08 |
EP0772490B1 (de) | 1998-11-11 |
ATE173181T1 (de) | 1998-11-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69505986T2 (de) | Vorrichtung zum chemischen mischen und reagieren | |
KR970702748A (ko) | 마이크로구조 혼합을 이용하여 화학 반응을 수행하는 방법 및 장치(Mtehod and Device for Performing Chemical Reactions with the Aid of Microstructure Mixing) | |
ATE287761T1 (de) | Verfahren und vorrichtung zum mischen kleinster flüssigkeitsmengen | |
DE3174615D1 (en) | Catalyst devices | |
DE3763940D1 (de) | Verfahren zum mischen von zwei oder mehr gasstroemen. | |
DE69524591D1 (de) | Vorrichtung und methoden zum abtrennen von feststoffen aus strömenden flüssigkeiten oder gasen | |
AU2001273957B2 (en) | Static mixing element | |
EP1380337A3 (de) | Vorrichtung mit feinen Kanälen und chemisches Verfahren zur Verwendung dieser Vorrichtung für Fluide | |
ATE482767T1 (de) | Verfahren und vorrichtung zur behandlung von fluiden | |
ATE13817T1 (de) | Vorrichtung zur erhoehung der homogenitaet einer mischung von fluiden, die in einer leitung zusammenfliessen. | |
JP2010505609A (ja) | 混合ゾーンを有する熱交換器反応器 | |
ATE238836T1 (de) | Mikromischer | |
DE60234423D1 (de) | Anordnung zum mischen von strömen bei einem papierherstellungsverfahren | |
DE60211923D1 (de) | Vorrichtung und verfahren zum inberührungbringen einer flüssigkeit mit einem gas | |
KR900018415A (ko) | 도체판의 처리 또는 청소 장치 | |
ATE47800T1 (de) | Vorrichtung zur feststoffbettpolymerisation von monomeren. | |
US20080230129A1 (en) | Device for Fluid Transport | |
ES2131695T3 (es) | Reactor y dispositivo de tratamientos fisico-quimicos de sustancias en estado solido, liquido o gaseoso. | |
EP1827676B1 (de) | Vorrichtung für den fluidtransport | |
DE69926875D1 (de) | Verfahren und vorrichtung zur behandlung einer flüssigen masse | |
UA42043C2 (uk) | Спосіб розпилу рідини та пристрій для його здійснення | |
SE8500711D0 (sv) | Spritsmunstycke for fogmassa | |
SE0103591L (sv) | Metod och anordning för att kontinuerligt blanda två flöden | |
DE68917532D1 (de) | Vorrichtung zur Behandlung von Blut. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |