DE69513156T2 - Kovalent gebundener überzug - Google Patents

Kovalent gebundener überzug

Info

Publication number
DE69513156T2
DE69513156T2 DE69513156T DE69513156T DE69513156T2 DE 69513156 T2 DE69513156 T2 DE 69513156T2 DE 69513156 T DE69513156 T DE 69513156T DE 69513156 T DE69513156 T DE 69513156T DE 69513156 T2 DE69513156 T2 DE 69513156T2
Authority
DE
Germany
Prior art keywords
tied
covalent
cover
tied cover
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69513156T
Other languages
English (en)
Other versions
DE69513156D1 (de
Inventor
Noubar Afeyan
Fred Regnier
Ning Mu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Purdue Research Foundation
Applied Biosystems LLC
Original Assignee
PerSeptive Biosystems Inc
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PerSeptive Biosystems Inc, Purdue Research Foundation filed Critical PerSeptive Biosystems Inc
Publication of DE69513156D1 publication Critical patent/DE69513156D1/de
Application granted granted Critical
Publication of DE69513156T2 publication Critical patent/DE69513156T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/261—Synthetic macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/264—Synthetic macromolecular compounds derived from different types of monomers, e.g. linear or branched copolymers, block copolymers, graft copolymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
    • B01J20/267—Cross-linked polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004—Sorbent size or size distribution, e.g. particle size
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28078—Pore diameter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/3092—Packing of a container, e.g. packing a cartridge or column
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/327—Polymers obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/328—Polymers on the carrier being further modified
    • B01J20/3282—Crosslinked polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/58—Use in a single column
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2998—Coated including synthetic resin or polymer
DE69513156T 1994-02-25 1995-02-24 Kovalent gebundener überzug Expired - Lifetime DE69513156T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/201,906 US5503933A (en) 1994-02-25 1994-02-25 Covalently bonded coatings
PCT/US1995/002318 WO1995023022A1 (en) 1994-02-25 1995-02-24 Covalently bonded coating

Publications (2)

Publication Number Publication Date
DE69513156D1 DE69513156D1 (de) 1999-12-09
DE69513156T2 true DE69513156T2 (de) 2000-04-27

Family

ID=22747772

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69513156T Expired - Lifetime DE69513156T2 (de) 1994-02-25 1995-02-24 Kovalent gebundener überzug

Country Status (5)

Country Link
US (1) US5503933A (de)
EP (1) EP0751823B1 (de)
AU (1) AU1931095A (de)
DE (1) DE69513156T2 (de)
WO (1) WO1995023022A1 (de)

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US5772874A (en) * 1995-11-02 1998-06-30 Cohesive Technologies, Inc. High performance liquid chromatography method and apparatus
CA2242885C (en) * 1996-01-19 2006-08-15 Cohesive Technologies, Inc. High performance liquid chromatography method and apparatus
US20040253279A1 (en) * 1996-10-04 2004-12-16 Dytech Corporation Limited Production of porous articles
US5936003A (en) * 1997-03-03 1999-08-10 Dionex Corporation Hydrolytically stable resins for use in anion-exchange chromatography
US5865994A (en) * 1997-03-13 1999-02-02 Dionex Corporation Bifunctional crown ether-based cation-exchange stationary phase for liquid chromatography
SE9702427D0 (sv) * 1997-06-25 1997-06-25 Pharmacia Biotech Ab Coated polymer article
US6110362A (en) * 1997-11-19 2000-08-29 Cohesive Technologies, Inc. Chemical analysis
DE10036907B4 (de) * 2000-07-28 2012-03-22 Xantec Bioanalytics Gmbh Verfahren zur Herstellung einer Beschichtung auf einem mit Gold bedampften Glassubstrat, Beschichtung hergestellt nach diesem Verfahren und deren Verwendung
KR20030023962A (ko) * 2001-09-14 2003-03-26 이호재 이온크로마토그래피 칼럼 충전제 및 그 제조방법
JP2005510609A (ja) * 2001-11-26 2005-04-21 アメルシャム・バイオサイエンシーズ・アクチボラグ 多孔性支持体の後修飾
AU2002353736B2 (en) * 2001-11-26 2008-05-08 Ge Healthcare Bio-Sciences Ab Post-modification of a porous support
WO2003072352A1 (en) * 2002-02-25 2003-09-04 Cabot Corporation Porous compositions comprising surface modified monoliths
WO2003072640A2 (en) * 2002-02-25 2003-09-04 Cabot Coproration Compositions comprising continuous networks and monoliths
US6749749B2 (en) * 2002-06-26 2004-06-15 Isco, Inc. Separation system, components of a separation system and methods of making and using them
US7473367B2 (en) * 2002-06-26 2009-01-06 Dionex Corporation Monolithic column
US20050061745A1 (en) * 2002-06-26 2005-03-24 Teledyne Isco, Inc. Separation system, components of a separation system and methods of making and using them
US7026014B2 (en) * 2003-02-07 2006-04-11 Clemson University Surface modification of substrates
US7147891B2 (en) * 2004-02-11 2006-12-12 Dionex Corporation Polymer substrate coated with weak cationic-exchange functional layer
JP4637533B2 (ja) * 2004-08-31 2011-02-23 信和化工株式会社 固相抽出用分離剤
US7811453B2 (en) * 2005-12-02 2010-10-12 Sekisui Chemical Co., Ltd. Hydrophilic polymer microparticle, filler for ion exchange liquid chromatography, and method for production of filler for ion exchange liquid chromatography
US20070141727A1 (en) * 2005-12-15 2007-06-21 Kimberly-Clark Worldwide, Inc. Luminescent metallic cluster particles and uses thereof
WO2009158071A2 (en) * 2008-06-26 2009-12-30 3M Innovative Properties Company Solid support with a grafted chain
CN102365262B (zh) 2009-03-31 2014-09-17 3M创新有限公司 疏水单体、疏水衍生载体及其制备和使用方法
US9486799B2 (en) * 2012-09-11 2016-11-08 Dionex Corporation Glycidol functionalized anion exchange stationary phases
US10641751B2 (en) 2015-06-19 2020-05-05 Dionex Corporation Ion exchange chromatography column, method, and system thereof
JP2017125815A (ja) * 2016-01-15 2017-07-20 日立化成株式会社 分離材及びカラム
JP6705189B2 (ja) * 2016-02-02 2020-06-03 日立化成株式会社 分離材及びカラム
US10379090B2 (en) 2016-06-17 2019-08-13 Dionex Corporation Charge reversible ion exchange resins, chromatography column, method, and system thereof
US11247192B2 (en) * 2016-08-26 2022-02-15 Showa Denko K.K. Packing material for HILIC columns, HILIC column filled with same, and method for analyzing oligosaccharide with use of same
JP7045373B2 (ja) * 2017-06-22 2022-03-31 昭和電工株式会社 オリゴヌクレオチドの混合物の分離分析方法
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EP4316645A1 (de) * 2022-08-05 2024-02-07 Metrohm AG Säurefunktionalisiertes ionenaustauschmaterial

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Also Published As

Publication number Publication date
AU1931095A (en) 1995-09-11
DE69513156D1 (de) 1999-12-09
US5503933A (en) 1996-04-02
WO1995023022A1 (en) 1995-08-31
EP0751823A1 (de) 1997-01-08
EP0751823B1 (de) 1999-11-03

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Legal Events

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8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: APPLIED BIOSYSTEMS, LLC (N. D. GES. D. STAATES, US

Owner name: PURDUE RESEARCH FOUNDATION, WEST LAFAYETTE, IN, US