DE69519664D1 - Verfahren zur herstellung fester pharmazeutischer dosierungsform - Google Patents

Verfahren zur herstellung fester pharmazeutischer dosierungsform

Info

Publication number
DE69519664D1
DE69519664D1 DE69519664T DE69519664T DE69519664D1 DE 69519664 D1 DE69519664 D1 DE 69519664D1 DE 69519664 T DE69519664 T DE 69519664T DE 69519664 T DE69519664 T DE 69519664T DE 69519664 D1 DE69519664 D1 DE 69519664D1
Authority
DE
Germany
Prior art keywords
dosage form
water
active substance
pharmaceutically active
pharmaceutical dosage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69519664T
Other languages
English (en)
Other versions
DE69519664T2 (de
Inventor
John Yarwood
Patrick Kearney
Roy Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RP Scherer Technologies LLC
Original Assignee
RP Scherer Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RP Scherer Technologies LLC filed Critical RP Scherer Technologies LLC
Publication of DE69519664D1 publication Critical patent/DE69519664D1/de
Application granted granted Critical
Publication of DE69519664T2 publication Critical patent/DE69519664T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D25/00—Filters formed by clamping together several filtering elements or parts of such elements
    • B01D25/12—Filter presses, i.e. of the plate or plate and frame type
    • B01D25/176—Filter presses, i.e. of the plate or plate and frame type attaching the filter element to the filter press plates, e.g. around the central feed hole in the plates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69519664T 1994-10-28 1995-10-20 Verfahren zur herstellung fester pharmazeutischer dosierungsform Expired - Lifetime DE69519664T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9421837A GB9421837D0 (en) 1994-10-28 1994-10-28 Process for preparing solid pharmaceutical dosage forms
CA002134611A CA2134611C (en) 1994-10-28 1994-10-28 Process for preparing solid pharmaceutical dosage forms
US08/330,936 US5738875A (en) 1994-10-28 1994-10-28 Process for preparing solid pharmaceutical dosage forms
PCT/GB1995/002486 WO1996013252A1 (en) 1994-10-28 1995-10-20 Process for preparing solid pharmaceutical dosage forms

Publications (2)

Publication Number Publication Date
DE69519664D1 true DE69519664D1 (de) 2001-01-25
DE69519664T2 DE69519664T2 (de) 2001-05-17

Family

ID=27169885

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69519664T Expired - Lifetime DE69519664T2 (de) 1994-10-28 1995-10-20 Verfahren zur herstellung fester pharmazeutischer dosierungsform

Country Status (16)

Country Link
US (1) US5738875A (de)
EP (1) EP0737065B1 (de)
JP (2) JP3839845B2 (de)
CN (1) CN1204877C (de)
AT (1) ATE198150T1 (de)
AU (1) AU3702895A (de)
CA (1) CA2134611C (de)
DE (1) DE69519664T2 (de)
DK (1) DK0737065T3 (de)
ES (1) ES2153498T3 (de)
GB (1) GB9421837D0 (de)
GR (1) GR3035194T3 (de)
MX (1) MX9602514A (de)
PT (1) PT737065E (de)
WO (1) WO1996013252A1 (de)
ZA (1) ZA959073B (de)

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US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
GB9702799D0 (en) * 1997-02-12 1997-04-02 Scherer Corp R P Process for preparing solid pharmaceutical dosage forms
US20040023948A1 (en) * 1997-03-24 2004-02-05 Green Richard David Fast-dispersing dosage form containing 5-HT1 agonists
US5976577A (en) * 1997-07-11 1999-11-02 Rp Scherer Corporation Process for preparing fast dispersing solid oral dosage form
DE19821625C1 (de) * 1998-05-15 2000-01-05 Merck Patent Gmbh Pharmazeutische Zubereitung
BR0007360A (pt) * 1999-12-23 2001-08-14 Johnson & Johnson Composição de liberação controlada
DE60107393T2 (de) * 2000-03-01 2005-12-01 Euro-Celtique S.A. Verwendung von tramadol zur herstellung eines arzneimittels zur behandlung von funktionelle gastrointestinale krankenheiten
US6814978B2 (en) 2000-12-29 2004-11-09 Mcneil-Ppc, Inc. Process for preparing a soft tablet
WO2002100381A1 (en) * 2001-06-07 2002-12-19 Tanabe Seiyaku Co., Ltd. Functional grain-containing preparations quickly disintegrated in the oral cavity
JP2005508888A (ja) * 2001-08-14 2005-04-07 バイオティ セラピーズ コーポレイション アルコール依存症またはアルコール中毒を治療する方法
CN1578657A (zh) * 2001-09-25 2005-02-09 兰贝克赛实验室有限公司 制备快速溶解剂型的方法
MXPA04002980A (es) * 2001-09-28 2005-06-20 Johnson & Johnson Formas de dosificacion que tienen un nucleo interior y coraza exterior con diferentes formas.
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
EP1485296B1 (de) * 2002-02-13 2011-07-20 Michael K. Weibel Arzneimitteldosenform und -herstellungsverfahren
CA2478411C (en) * 2002-03-12 2010-09-28 Bristol-Myers Squibb Company Palatable oral suspension and method
US20040001885A1 (en) * 2002-06-27 2004-01-01 Unchalee Kositprapa Rapidly disintegrating antihistamine formulation
US7985422B2 (en) * 2002-08-05 2011-07-26 Torrent Pharmaceuticals Limited Dosage form
US8367111B2 (en) * 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US20040234579A1 (en) * 2003-05-22 2004-11-25 Mark D. Finke, Inc. Dietary supplements and methods of preparing and administering dietary supplements
US20050036977A1 (en) * 2003-08-11 2005-02-17 Dilip Gole Taste-masked resinate and preparation thereof
CA2540040C (en) * 2003-10-07 2012-09-11 Andrx Pharmaceuticals Llc Rapidly disintegrating formulation
DE20321887U1 (de) 2003-11-10 2012-01-20 Allergan, Inc. Arzneimittel umfassend niedrige Dosierungen von Desmopressin
EP1689419A4 (de) 2003-11-10 2009-01-14 Reprise Biopharmaceutics Llc Pharmazeutische zusammensetzungen mit niedrigen dosen von desmopressin
EP1582221A1 (de) 2004-03-31 2005-10-05 Chiesi S.A. Orale Pharmazeutische zusammensetzung zur Geschmacksmaskierung
US8545881B2 (en) * 2004-04-19 2013-10-01 Eurand Pharmaceuticals, Ltd. Orally disintegrating tablets and methods of manufacture
US8747895B2 (en) * 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) * 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
NZ589750A (en) 2004-10-21 2012-07-27 Aptalis Pharmatech Inc Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
ITMI20042356A1 (it) * 2004-12-10 2005-03-10 Acraf Composizione farmaceutica orodisperdibile e procedimento per prepararla
US8697674B2 (en) * 2004-12-29 2014-04-15 Naturon, Inc. Xanthurenic acid derivative pharmaceutical compositions and methods related thereto
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
GB0516604D0 (en) * 2005-08-12 2005-09-21 Sandoz Ag Rapidly dispersing/disintegrating compositions
US7811604B1 (en) 2005-11-14 2010-10-12 Barr Laboratories, Inc. Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same
US20070293581A1 (en) * 2006-06-05 2007-12-20 Malcolm Hill Methods for Buccal, Lingual or Sublingual Dosing Regimens of Epinephrine for the Treatment of Allergic Emergencies
TW200817049A (en) * 2006-06-05 2008-04-16 Verus Pharmaceuticals Inc Epinephrine dosing regimens comprising buccal, lingual or sublingual and injectable dosage forms
WO2011026080A1 (en) 2009-08-31 2011-03-03 Wilmington Pharmaceuticals, Llc Fast disintegrating compositions of meloxicam, processes for preparation, and use to treat arthritis and/or pain
JP5309262B2 (ja) 2009-12-02 2013-10-09 アプタリス ファーマ リミテッド フェキソフェナジン・マイクロカプセル及びそれを含む組成物
TW201127375A (en) * 2010-01-08 2011-08-16 Eurand Inc Taste masked topiramate composition and an orally disintegrating tablet comprising the same
US10548839B2 (en) * 2010-03-16 2020-02-04 Wei Tian Process of manufacturing a lyophilized fast dissolving, multi-phasic dosage form
CA2819663C (en) 2010-12-02 2019-12-24 Aptalis Pharmatech, Inc. Rapidly dispersing granules, orally disintegrating tablets and methods
US9511028B2 (en) 2012-05-01 2016-12-06 Johnson & Johnson Consumer Inc. Orally disintegrating tablet
MX365914B (es) 2013-03-15 2019-06-20 Aprecia Pharmaceuticals LLC Forma de dosificación de topiramato dispersable rápidamente.
US9339489B2 (en) 2013-03-15 2016-05-17 Aprecia Pharmaceuticals Company Rapid disperse dosage form containing levetiracetam
WO2014143935A1 (en) 2013-03-15 2014-09-18 Aprecia Pharmaceuticals Company Rapidly dispersible dosage form of oxcarbazepine
EP2968994B1 (de) 2013-03-15 2018-08-15 Aprecia Pharmaceuticals LLC Schnell dispergierende darreichungsform mit levetiracetam
ES2750323T3 (es) 2014-01-10 2020-03-25 Johnson & Johnson Consumer Inc Método para la fabricación de un comprimido mediante radiofrecuencia y partículas recubiertas con pérdida
WO2016042372A1 (en) 2014-09-17 2016-03-24 Steer Engineering Private Limited Effervescent composition and method of making it
WO2017098481A1 (en) 2015-12-12 2017-06-15 Steerlife India Private Limited Effervescent compositions of metformin and processes for preparation thereof
WO2017168174A1 (en) 2016-04-02 2017-10-05 N4 Pharma Uk Limited New pharmaceutical forms of sildenafil
WO2018002673A1 (en) 2016-07-01 2018-01-04 N4 Pharma Uk Limited Novel formulations of angiotensin ii receptor antagonists
IT201600078683A1 (it) * 2016-07-27 2018-01-27 Mattia Saporiti Matrice edibile per uso veterinario e zootecnico e relativo metodo di produzione
WO2018115888A1 (en) 2016-12-21 2018-06-28 N4 Pharma Uk Limited Novel formulations of aprepitant
US10493026B2 (en) 2017-03-20 2019-12-03 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles
EP3883546A1 (de) 2018-11-21 2021-09-29 Rosemont Pharmaceuticals Ltd Orale topiramat-suspensionsformulierungen mit verlängerter lagerstabilität und verbesserter bioverfügbarkeit
EP3927312B1 (de) 2019-02-22 2023-09-13 Catalent U.K. Swindon Zydis Limited Minimierung der agglomeration, belüftung und konservierung der beschichtung von pharmazeutischen zusammensetzungen mit ibuprofen
JP2023533478A (ja) 2020-06-26 2023-08-03 アプレシア・ファーマスーティカルズ・エルエルシー 内部空洞を有する迅速口内分散可能な錠剤
WO2022179634A1 (zh) * 2021-02-27 2022-09-01 北京兴源联合医药科技有限公司 一种冻干口服制剂

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Also Published As

Publication number Publication date
ES2153498T3 (es) 2001-03-01
MX9602514A (es) 1997-05-31
JP3839845B2 (ja) 2006-11-01
CN1204877C (zh) 2005-06-08
WO1996013252A1 (en) 1996-05-09
AU3702895A (en) 1996-05-23
EP0737065B1 (de) 2000-12-20
GR3035194T3 (en) 2001-04-30
CA2134611C (en) 2002-12-24
CA2134611A1 (en) 1996-04-29
US5738875A (en) 1998-04-14
PT737065E (pt) 2001-04-30
ZA959073B (en) 1996-05-22
DE69519664T2 (de) 2001-05-17
DK0737065T3 (da) 2001-01-15
JP2006111635A (ja) 2006-04-27
JPH09511256A (ja) 1997-11-11
GB9421837D0 (en) 1994-12-14
EP0737065A1 (de) 1996-10-16
CN1140407A (zh) 1997-01-15
ATE198150T1 (de) 2001-01-15

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Legal Events

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8364 No opposition during term of opposition