DE69519664T2 - Verfahren zur herstellung fester pharmazeutischer dosierungsform - Google Patents

Verfahren zur herstellung fester pharmazeutischer dosierungsform

Info

Publication number
DE69519664T2
DE69519664T2 DE69519664T DE69519664T DE69519664T2 DE 69519664 T2 DE69519664 T2 DE 69519664T2 DE 69519664 T DE69519664 T DE 69519664T DE 69519664 T DE69519664 T DE 69519664T DE 69519664 T2 DE69519664 T2 DE 69519664T2
Authority
DE
Germany
Prior art keywords
dosage form
water
active substance
pharmaceutically active
pharmaceutical dosage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69519664T
Other languages
English (en)
Other versions
DE69519664D1 (de
Inventor
John Yarwood
Patrick Kearney
Roy Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RP Scherer Technologies LLC
Original Assignee
RP Scherer Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RP Scherer Technologies LLC filed Critical RP Scherer Technologies LLC
Application granted granted Critical
Publication of DE69519664D1 publication Critical patent/DE69519664D1/de
Publication of DE69519664T2 publication Critical patent/DE69519664T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D25/00—Filters formed by clamping together several filtering elements or parts of such elements
    • B01D25/12—Filter presses, i.e. of the plate or plate and frame type
    • B01D25/176—Filter presses, i.e. of the plate or plate and frame type attaching the filter element to the filter press plates, e.g. around the central feed hole in the plates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
DE69519664T 1994-10-28 1995-10-20 Verfahren zur herstellung fester pharmazeutischer dosierungsform Expired - Lifetime DE69519664T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/330,936 US5738875A (en) 1994-10-28 1994-10-28 Process for preparing solid pharmaceutical dosage forms
GB9421837A GB9421837D0 (en) 1994-10-28 1994-10-28 Process for preparing solid pharmaceutical dosage forms
CA002134611A CA2134611C (en) 1994-10-28 1994-10-28 Process for preparing solid pharmaceutical dosage forms
PCT/GB1995/002486 WO1996013252A1 (en) 1994-10-28 1995-10-20 Process for preparing solid pharmaceutical dosage forms

Publications (2)

Publication Number Publication Date
DE69519664D1 DE69519664D1 (de) 2001-01-25
DE69519664T2 true DE69519664T2 (de) 2001-05-17

Family

ID=27169885

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69519664T Expired - Lifetime DE69519664T2 (de) 1994-10-28 1995-10-20 Verfahren zur herstellung fester pharmazeutischer dosierungsform

Country Status (16)

Country Link
US (1) US5738875A (de)
EP (1) EP0737065B1 (de)
JP (2) JP3839845B2 (de)
CN (1) CN1204877C (de)
AT (1) ATE198150T1 (de)
AU (1) AU3702895A (de)
CA (1) CA2134611C (de)
DE (1) DE69519664T2 (de)
DK (1) DK0737065T3 (de)
ES (1) ES2153498T3 (de)
GB (1) GB9421837D0 (de)
GR (1) GR3035194T3 (de)
MX (1) MX9602514A (de)
PT (1) PT737065E (de)
WO (1) WO1996013252A1 (de)
ZA (1) ZA959073B (de)

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US5976577A (en) * 1997-07-11 1999-11-02 Rp Scherer Corporation Process for preparing fast dispersing solid oral dosage form
DE19821625C1 (de) * 1998-05-15 2000-01-05 Merck Patent Gmbh Pharmazeutische Zubereitung
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JP5042425B2 (ja) * 2000-03-01 2012-10-03 ユーロセルティック ソシエテ アノニム 機能性胃腸疾患治療用トラマドール
US6814978B2 (en) 2000-12-29 2004-11-09 Mcneil-Ppc, Inc. Process for preparing a soft tablet
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US20040258748A1 (en) * 2001-09-25 2004-12-23 Ashish Madan Process for the preparation of fast dissolving dosage form
JP2005508325A (ja) * 2001-09-28 2005-03-31 マクニール−ピーピーシー・インコーポレイテッド 内側コア及び外側シェルを有する投薬形態
US9358214B2 (en) * 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
CN100556762C (zh) * 2002-02-13 2009-11-04 迈克尔K·韦伯尔 药物剂型及其制造方法
EP1482789A4 (de) * 2002-03-12 2010-12-29 Toyama Chemical Company Ltd Schmackhafte oralsuspension und verfahren
US20040001885A1 (en) * 2002-06-27 2004-01-01 Unchalee Kositprapa Rapidly disintegrating antihistamine formulation
US7985422B2 (en) * 2002-08-05 2011-07-26 Torrent Pharmaceuticals Limited Dosage form
US8367111B2 (en) * 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US20040234579A1 (en) * 2003-05-22 2004-11-25 Mark D. Finke, Inc. Dietary supplements and methods of preparing and administering dietary supplements
US20050036977A1 (en) * 2003-08-11 2005-02-17 Dilip Gole Taste-masked resinate and preparation thereof
JP2007507548A (ja) * 2003-10-07 2007-03-29 アンドルックス ファーマスーティカルズ リミテッド ライアビリティ カンパニー 速崩壊型製剤
DE20321887U1 (de) 2003-11-10 2012-01-20 Allergan, Inc. Arzneimittel umfassend niedrige Dosierungen von Desmopressin
EP2322198A2 (de) 2003-11-10 2011-05-18 Reprise Biopharmaceutics, LLC Pharmazeutische Zusammensetzungen mit niedrigen Dosen von Desmopressin
EP1582221A1 (de) 2004-03-31 2005-10-05 Chiesi S.A. Orale Pharmazeutische zusammensetzung zur Geschmacksmaskierung
US8545881B2 (en) 2004-04-19 2013-10-01 Eurand Pharmaceuticals, Ltd. Orally disintegrating tablets and methods of manufacture
US8747895B2 (en) * 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
EP2417969A1 (de) 2004-10-21 2012-02-15 Aptalis Pharmatech, Inc. Geschmacksverdeckende pharmazeutische Zusammensetzungen mit magenlöslichen Porenbildnern
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
ITMI20042356A1 (it) * 2004-12-10 2005-03-10 Acraf Composizione farmaceutica orodisperdibile e procedimento per prepararla
US8697674B2 (en) * 2004-12-29 2014-04-15 Naturon, Inc. Xanthurenic acid derivative pharmaceutical compositions and methods related thereto
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
GB0516604D0 (en) * 2005-08-12 2005-09-21 Sandoz Ag Rapidly dispersing/disintegrating compositions
US7811604B1 (en) 2005-11-14 2010-10-12 Barr Laboratories, Inc. Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same
WO2007143676A2 (en) * 2006-06-05 2007-12-13 Verus Pharmaceuticals, Inc. Epinephrine dosing regimens comprising buccal, lingual or sublingual and injectable dosage forms
TW200816985A (en) * 2006-06-05 2008-04-16 Verus Pharmaceuticals Inc Methods for buccal, lingual or sublingual dosing regimens of epinephrine for the treatment of allergic emergencies
WO2011026080A1 (en) 2009-08-31 2011-03-03 Wilmington Pharmaceuticals, Llc Fast disintegrating compositions of meloxicam, processes for preparation, and use to treat arthritis and/or pain
CA2782285A1 (en) 2009-12-02 2011-06-09 Luigi Mapelli Fexofenadine microcapsules and compositions containing them
WO2011085181A1 (en) * 2010-01-08 2011-07-14 Eurand, Inc. Taste masked topiramate composition and an orally disintegrating tablet comprising the same
US10548839B2 (en) 2010-03-16 2020-02-04 Wei Tian Process of manufacturing a lyophilized fast dissolving, multi-phasic dosage form
US20120282335A1 (en) 2010-12-02 2012-11-08 Aptalis Pharmatech Inc. Rapidly dispersing granules, orally disintegrating tablets and methods
US9511028B2 (en) 2012-05-01 2016-12-06 Johnson & Johnson Consumer Inc. Orally disintegrating tablet
WO2014144661A1 (en) 2013-03-15 2014-09-18 Aprecia Pharmaceuticals Compny Rapidly dispersible dosage form of topiramate
CN105050604B (zh) 2013-03-15 2021-10-26 阿普雷奇亚制药有限责任公司 奥卡西平的快速分散剂型
AU2014228990B2 (en) 2013-03-15 2017-02-02 Aprecia Pharmaceuticals LLC Rapid disperse dosage form containing levetiracetam
US9339489B2 (en) 2013-03-15 2016-05-17 Aprecia Pharmaceuticals Company Rapid disperse dosage form containing levetiracetam
AU2015204763A1 (en) 2014-01-10 2016-07-21 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles
CA3018828C (en) 2014-09-17 2021-05-11 Steerlife India Private Limited Effervescent composition and method of making it
US11219594B2 (en) 2015-12-12 2022-01-11 Steerlife India Private Limited Effervescent compositions of metformin and processes for preparation thereof
WO2017168174A1 (en) 2016-04-02 2017-10-05 N4 Pharma Uk Limited New pharmaceutical forms of sildenafil
WO2018002673A1 (en) 2016-07-01 2018-01-04 N4 Pharma Uk Limited Novel formulations of angiotensin ii receptor antagonists
IT201600078683A1 (it) * 2016-07-27 2018-01-27 Mattia Saporiti Matrice edibile per uso veterinario e zootecnico e relativo metodo di produzione
WO2018115888A1 (en) 2016-12-21 2018-06-28 N4 Pharma Uk Limited Novel formulations of aprepitant
US10493026B2 (en) 2017-03-20 2019-12-03 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles
EP3883546A1 (de) 2018-11-21 2021-09-29 Rosemont Pharmaceuticals Ltd Orale topiramat-suspensionsformulierungen mit verlängerter lagerstabilität und verbesserter bioverfügbarkeit
JP2022521318A (ja) 2019-02-22 2022-04-06 キャタレント・ユーケー・スウィンドン・ザイディス・リミテッド イブプロフェンを含む薬学的組成物の凝集、通気の最小化、及びコーティングの保存
EP4171518A1 (de) 2020-06-26 2023-05-03 Aprecia Pharmaceuticals LLC Schnell im mund dispergierbare tabletten mit einem inneren hohlraum
WO2022179634A1 (zh) * 2021-02-27 2022-09-01 北京兴源联合医药科技有限公司 一种冻干口服制剂

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ATE212235T1 (de) * 1991-04-08 2002-02-15 Sumitomo Pharma Poröse feste zubereitung, die eine physiologische aktive proteinverbindung enthält
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US5738875A (en) * 1994-10-28 1998-04-14 R.P. Scherer Corporation Process for preparing solid pharmaceutical dosage forms

Also Published As

Publication number Publication date
GB9421837D0 (en) 1994-12-14
CN1140407A (zh) 1997-01-15
ZA959073B (en) 1996-05-22
CN1204877C (zh) 2005-06-08
PT737065E (pt) 2001-04-30
MX9602514A (es) 1997-05-31
EP0737065A1 (de) 1996-10-16
GR3035194T3 (en) 2001-04-30
CA2134611C (en) 2002-12-24
AU3702895A (en) 1996-05-23
US5738875A (en) 1998-04-14
EP0737065B1 (de) 2000-12-20
JP3839845B2 (ja) 2006-11-01
DK0737065T3 (da) 2001-01-15
JP2006111635A (ja) 2006-04-27
ATE198150T1 (de) 2001-01-15
WO1996013252A1 (en) 1996-05-09
JPH09511256A (ja) 1997-11-11
DE69519664D1 (de) 2001-01-25
ES2153498T3 (es) 2001-03-01
CA2134611A1 (en) 1996-04-29

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Legal Events

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8364 No opposition during term of opposition