DE69526364D1 - Patch-clamp-vorrichtung und -technik mit hohem durchfluss und niedrigen flüssigkeitsvolumenanforderungen - Google Patents

Patch-clamp-vorrichtung und -technik mit hohem durchfluss und niedrigen flüssigkeitsvolumenanforderungen

Info

Publication number
DE69526364D1
DE69526364D1 DE69526364T DE69526364T DE69526364D1 DE 69526364 D1 DE69526364 D1 DE 69526364D1 DE 69526364 T DE69526364 T DE 69526364T DE 69526364 T DE69526364 T DE 69526364T DE 69526364 D1 DE69526364 D1 DE 69526364D1
Authority
DE
Germany
Prior art keywords
patch clamp
utilizing
novel
tested
technology
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69526364T
Other languages
English (en)
Other versions
DE69526364T2 (de
Inventor
S Ren-Peter Olesen
Palle Christophersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sophion Bioscience AS
Original Assignee
Sophion Bioscience AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sophion Bioscience AS filed Critical Sophion Bioscience AS
Publication of DE69526364D1 publication Critical patent/DE69526364D1/de
Application granted granted Critical
Publication of DE69526364T2 publication Critical patent/DE69526364T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
    • G01N35/1097—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers characterised by the valves
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/04—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48728—Investigating individual cells, e.g. by patch clamp, voltage clamp
DE69526364T 1994-10-28 1995-06-07 Patch-clamp-vorrichtung und -technik mit hohem durchfluss und niedrigen flüssigkeitsvolumenanforderungen Expired - Lifetime DE69526364T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK125294 1994-10-28
PCT/EP1995/002204 WO1996013721A1 (en) 1994-10-28 1995-06-07 Patch clamp apparatus and technique having high throughput and low fluid volume requirements

Publications (2)

Publication Number Publication Date
DE69526364D1 true DE69526364D1 (de) 2002-05-16
DE69526364T2 DE69526364T2 (de) 2002-11-28

Family

ID=8102743

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69526364T Expired - Lifetime DE69526364T2 (de) 1994-10-28 1995-06-07 Patch-clamp-vorrichtung und -technik mit hohem durchfluss und niedrigen flüssigkeitsvolumenanforderungen

Country Status (12)

Country Link
US (2) US6063260A (de)
EP (1) EP0788600B1 (de)
JP (1) JP3688713B2 (de)
AT (1) ATE216080T1 (de)
AU (1) AU2788695A (de)
CA (1) CA2203886C (de)
DE (1) DE69526364T2 (de)
DK (1) DK0788600T3 (de)
ES (1) ES2171542T3 (de)
PT (1) PT788600E (de)
SI (1) SI0788600T1 (de)
WO (1) WO1996013721A1 (de)

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IL143213A0 (en) 1998-12-05 2002-04-21 Cenes Ltd Interface patch clamping
DE19936302A1 (de) * 1999-08-02 2001-02-15 Niels Fertig Vorrichtungen und Verfahren zur Untersuchung von Ionenkanälen in Membranen
US6488829B1 (en) 1999-08-05 2002-12-03 Essen Instruments Inc High-throughput electrophysiological measurement apparatus
DE10008373C2 (de) * 2000-02-23 2002-11-28 Helmut Adelsberger Verfahren und Vorrichtung zur Bestimmung der Ionenkanalaktivität
US20030139336A1 (en) * 2000-03-21 2003-07-24 Norwood James Henry Interface patch clamping
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US6686193B2 (en) 2000-07-10 2004-02-03 Vertex Pharmaceuticals, Inc. High throughput method and system for screening candidate compounds for activity against target ion channels
US7615356B2 (en) * 2000-07-10 2009-11-10 Vertex Pharmaceuticals (San Diego) Llc Ion channel assay methods
US7067046B2 (en) * 2000-08-04 2006-06-27 Essen Instruments, Inc. System for rapid chemical activation in high-throughput electrophysiological measurements
US7270730B2 (en) * 2000-08-04 2007-09-18 Essen Instruments, Inc. High-throughput electrophysiological measurement system
WO2002059597A1 (en) * 2001-01-26 2002-08-01 Cytion Sa Methods and devices for the electrically tight adhesion of a cell to a surface
US6815197B2 (en) * 2001-02-16 2004-11-09 Multi Channel System Mcs Gmbh Apparatus for conducting electrophysiological measurements on cells
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US20050058990A1 (en) * 2001-03-24 2005-03-17 Antonio Guia Biochip devices for ion transport measurement, methods of manufacture, and methods of use
US20050196746A1 (en) * 2001-03-24 2005-09-08 Jia Xu High-density ion transport measurement biochip devices and methods
US20060029955A1 (en) 2001-03-24 2006-02-09 Antonio Guia High-density ion transport measurement biochip devices and methods
US20040146849A1 (en) * 2002-01-24 2004-07-29 Mingxian Huang Biochips including ion transport detecting structures and methods of use
WO2002077259A2 (en) * 2001-03-24 2002-10-03 Aviva Biosciences Corporation Biochips including ion transport detecting structures and methods of use
US20050009004A1 (en) * 2002-05-04 2005-01-13 Jia Xu Apparatus including ion transport detecting structures and methods of use
US6969489B2 (en) 2001-08-24 2005-11-29 Cytoplex Biosciences Micro array for high throughout screening
WO2003021230A2 (en) * 2001-09-05 2003-03-13 Essen Instruments, Inc. High-throughput electrophysiological measurement system
JP2005511039A (ja) * 2001-11-30 2005-04-28 ブリストル−マイヤーズ　スクイブ　カンパニー 自動パッチクランプ記録用液体界面形態
AU2002352988A1 (en) * 2001-11-30 2003-06-17 Bristol-Myers Squibb Company Pipette configurations and arrays thereof for measuring cellular electrical properties
DE10202887B4 (de) * 2002-01-25 2004-05-06 Advalytix Ag Zellanalyseverfahren
EP1476536B1 (de) * 2002-02-12 2011-07-20 Cellectricon Ab Systeme und verfahren zur schnellen änderung der lösungsumgebung von sensoren
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US8202439B2 (en) * 2002-06-05 2012-06-19 Panasonic Corporation Diaphragm and device for measuring cellular potential using the same, manufacturing method of the diaphragm
JP4552423B2 (ja) * 2003-11-21 2010-09-29 パナソニック株式会社 細胞外電位測定デバイスおよびこれを用いた細胞外電位の測定方法
FR2844052B1 (fr) 2002-08-28 2005-07-01 Commissariat Energie Atomique Dispositif de mesure de l'activite electrique d'elements biologiques et ses applications
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US20050241940A1 (en) * 2004-05-03 2005-11-03 Wyeth Fast perfusion system and patch clamp technique utilizing an interface chamber system having high throughput and low volume requirements
US7465558B2 (en) * 2004-05-12 2008-12-16 Wyeth Perfusion system and apparatus for automated multi-channel patch-clamp recordings utilizing inside-out whole-cell configuration
US8211386B2 (en) * 2004-06-08 2012-07-03 Biokit, S.A. Tapered cuvette and method of collecting magnetic particles
HUE032640T2 (en) 2005-11-08 2017-10-30 Vertex Pharma Heterocyclic modulator of ATP-binding cassette transcripts
JP2013523833A (ja) 2010-04-07 2013-06-17 バーテックス ファーマシューティカルズ インコーポレイテッド ３−（６−（１−（２，２−ジフルオロベンゾ［ｄ］［１，３］ジオキソール−５−イル）シクロプロパンカルボキサミド）−３−メチルピリジン−２−イル）安息香酸の医薬組成物およびその投与
US9086401B2 (en) * 2013-03-06 2015-07-21 Wisconsin Alumni Research Foundation Radio-frequency ion channel antenna
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US10479972B2 (en) * 2015-04-20 2019-11-19 Rush University Medical Center Chamber for imaging cells and method of use thereof
US10324080B2 (en) * 2015-11-17 2019-06-18 Purdue Research Foundation Systems and methods for automated image-guided patch-clamp electrophysiology in vitro
US11215606B2 (en) 2016-12-02 2022-01-04 Sophion Bioscience A/S Seal enhancer
US11073508B2 (en) 2017-03-28 2021-07-27 Arizona Board Of Regents On Behalf Of The University Of Arizona Rapid conductance based ion channel analysis
WO2022214558A1 (en) * 2021-04-07 2022-10-13 Norgren LLC Bioprocessing systems

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Also Published As

Publication number Publication date
US6063260A (en) 2000-05-16
EP0788600B1 (de) 2002-04-10
EP0788600A1 (de) 1997-08-13
ATE216080T1 (de) 2002-04-15
PT788600E (pt) 2002-07-31
DE69526364T2 (de) 2002-11-28
AU2788695A (en) 1996-05-23
JP3688713B2 (ja) 2005-08-31
CA2203886C (en) 2003-09-02
SI0788600T1 (en) 2002-06-30
US6117291A (en) 2000-09-12
CA2203886A1 (en) 1996-05-09
JPH10509794A (ja) 1998-09-22
DK0788600T3 (da) 2002-08-05
WO1996013721A1 (en) 1996-05-09
ES2171542T3 (es) 2002-09-16

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Legal Events

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8328 Change in the person/name/address of the agent

Representative=s name: KUDLEK & GRUNERT PATENTANWAELTE PARTNERSCHAFT, 803