DE69533514D1 - Antigenes Fragment des tagA-Gens und Methoden zum Nachweis der Prädisposition von Magengeschwür und Magenkarzinom - Google Patents

Antigenes Fragment des tagA-Gens und Methoden zum Nachweis der Prädisposition von Magengeschwür und Magenkarzinom

Info

Publication number
DE69533514D1
DE69533514D1 DE69533514T DE69533514T DE69533514D1 DE 69533514 D1 DE69533514 D1 DE 69533514D1 DE 69533514 T DE69533514 T DE 69533514T DE 69533514 T DE69533514 T DE 69533514T DE 69533514 D1 DE69533514 D1 DE 69533514D1
Authority
DE
Germany
Prior art keywords
antigen
detecting
predisposition
taga
gastric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69533514T
Other languages
English (en)
Other versions
DE69533514T2 (de
Inventor
Timothy L Cover
Martin J Blaser
Harry Kleanthous
Murali K R Tummuru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur Biologics LLC
Vanderbilt University
Original Assignee
OraVax Inc
Vanderbilt University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by OraVax Inc, Vanderbilt University filed Critical OraVax Inc
Application granted granted Critical
Publication of DE69533514D1 publication Critical patent/DE69533514D1/de
Publication of DE69533514T2 publication Critical patent/DE69533514T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56922—Campylobacter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57446—Specifically defined cancers of stomach or intestine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/205—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Campylobacter (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases
    • G01N2800/062—Gastritis or peptic ulcer disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease
DE69533514T 1994-09-30 1995-09-29 Antigenes Fragment des tagA-Gens und Methoden zum Nachweis der Prädisposition von Magengeschwür und Magenkarzinom Expired - Fee Related DE69533514T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/316,397 US5733740A (en) 1992-10-13 1994-09-30 Taga gene and methods for detecting predisposition to peptic ulceration and gastric carcinoma
US316397 1994-09-30
PCT/US1995/012669 WO1996010639A2 (en) 1994-09-30 1995-09-29 THE tagA GENE AND METHODS FOR DETECTING PREDISPOSITION TO PEPTIC ULCERATION AND GASTRIC CARCINOMA

Publications (2)

Publication Number Publication Date
DE69533514D1 true DE69533514D1 (de) 2004-10-21
DE69533514T2 DE69533514T2 (de) 2005-09-15

Family

ID=23228874

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69533514T Expired - Fee Related DE69533514T2 (de) 1994-09-30 1995-09-29 Antigenes Fragment des tagA-Gens und Methoden zum Nachweis der Prädisposition von Magengeschwür und Magenkarzinom

Country Status (16)

Country Link
US (3) US5733740A (de)
EP (1) EP0783579B1 (de)
JP (1) JPH10509864A (de)
CN (1) CN1166858A (de)
AT (1) ATE276365T1 (de)
CA (1) CA2201353A1 (de)
CZ (1) CZ96697A3 (de)
DE (1) DE69533514T2 (de)
ES (1) ES2231792T3 (de)
FI (1) FI971326A (de)
HU (1) HUT76730A (de)
MX (1) MX9702335A (de)
NO (1) NO971473L (de)
NZ (1) NZ295297A (de)
PL (1) PL319441A1 (de)
WO (1) WO1996010639A2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7141244B1 (en) * 1992-03-02 2006-11-28 Chiron Srl Helicobacter pylori proteins useful for vaccines and diagnostics
WO1993018150A1 (en) * 1992-03-02 1993-09-16 Biocine S.P.A. Helicobacter pylori proteins useful for vaccines and diagnostics
US5733740A (en) * 1992-10-13 1998-03-31 Vanderbilt University Taga gene and methods for detecting predisposition to peptic ulceration and gastric carcinoma
US6290962B1 (en) 1992-11-03 2001-09-18 Oravax, Inc. Urease-based vaccine and treatment for helicobacter infection
US5972336A (en) * 1992-11-03 1999-10-26 Oravax Merieux Co. Urease-based vaccine against helicobacter infection
EP0769018B1 (de) * 1994-07-01 2002-12-18 Chiron Corporation Helicobacter proteine und impstoffe
EP0909323B1 (de) * 1996-01-04 2007-02-28 Novartis Vaccines and Diagnostics, Inc. Bakterioferritin aus helicobacter pylori
CA2271774A1 (en) * 1996-11-14 1998-05-22 Merieux Oravax Helicobacter polypeptides and corresponding polynucleotide molecules
US6902903B1 (en) * 1996-12-19 2005-06-07 Chiron Corporation Helicobacter pylori diagnostics
TWI237695B (en) * 1999-12-14 2005-08-11 Joy Biomedical Corp Helicobacter pylori antigens in blood
WO2003018054A1 (en) * 2001-08-31 2003-03-06 Chiron Srl. Helicobacter pylori vaccination
FI118061B (fi) * 2001-09-24 2007-06-15 Beanor Oy Menetelmä ja bioanturi analyysiä varten
AU2002359817A1 (en) * 2001-12-21 2003-07-30 Diadexus, Inc. Compositions and methods relating to gastric specific genes and proteins
FI115166B (fi) * 2001-12-31 2005-03-15 Biofons Oy Diagnostisia menetelmiä
CN1622997A (zh) * 2002-03-26 2005-06-01 北京大学临床肿瘤学院 检测幽门螺杆菌相关胃癌遗传易感性的方法及其用途
TWI276631B (en) * 2002-09-12 2007-03-21 Avanir Pharmaceuticals Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
US20040142379A1 (en) 2003-01-16 2004-07-22 Carlsberg Research Laboratory Affinity fishing for ligands and proteins receptors
CN102078622A (zh) 2004-08-13 2011-06-01 巴里.J.马沙尔 细菌递送系统
US8029777B2 (en) * 2004-08-13 2011-10-04 Marshall Barry J Helicobacter system and uses thereof
EP1853914B1 (de) * 2005-01-25 2015-04-22 The Johns Hopkins University Plasmodium-diagnosetest

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262156A (en) * 1991-08-12 1993-11-16 Hycor Biomedical, Inc. Antigenic compositions and their use for the detection of Helicobacter pylori
WO1993018150A1 (en) * 1992-03-02 1993-09-16 Biocine S.P.A. Helicobacter pylori proteins useful for vaccines and diagnostics
US5733740A (en) * 1992-10-13 1998-03-31 Vanderbilt University Taga gene and methods for detecting predisposition to peptic ulceration and gastric carcinoma
US5403924A (en) * 1992-10-13 1995-04-04 Vanderbilt University Taga gene and methods for detecting predisposition to peptic ulceration

Also Published As

Publication number Publication date
NO971473D0 (no) 1997-04-01
MX9702335A (es) 1997-10-31
NZ295297A (en) 1999-03-29
AU703075B2 (en) 1999-03-11
FI971326A0 (fi) 1997-03-27
CN1166858A (zh) 1997-12-03
DE69533514T2 (de) 2005-09-15
US5733740A (en) 1998-03-31
US5876943A (en) 1999-03-02
AU3858995A (en) 1996-04-26
PL319441A1 (en) 1997-08-04
EP0783579A2 (de) 1997-07-16
EP0783579B1 (de) 2004-09-15
WO1996010639A2 (en) 1996-04-11
CZ96697A3 (en) 1997-10-15
FI971326A (fi) 1997-05-27
CA2201353A1 (en) 1996-04-11
ES2231792T3 (es) 2005-05-16
US6153390A (en) 2000-11-28
JPH10509864A (ja) 1998-09-29
NO971473L (no) 1997-05-29
ATE276365T1 (de) 2004-10-15
HUT76730A (en) 1997-11-28
WO1996010639A3 (en) 1996-05-17

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Legal Events

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8339 Ceased/non-payment of the annual fee