DE69534373D1 - Chemische veränderung von repetitiven polymeren zur erhöhung der wasserlöslichkeit - Google Patents

Chemische veränderung von repetitiven polymeren zur erhöhung der wasserlöslichkeit

Info

Publication number
DE69534373D1
DE69534373D1 DE69534373T DE69534373T DE69534373D1 DE 69534373 D1 DE69534373 D1 DE 69534373D1 DE 69534373 T DE69534373 T DE 69534373T DE 69534373 T DE69534373 T DE 69534373T DE 69534373 D1 DE69534373 D1 DE 69534373D1
Authority
DE
Germany
Prior art keywords
water solubility
chemical change
increase water
protein
repetitive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69534373T
Other languages
English (en)
Other versions
DE69534373T2 (de
Inventor
Erwin R Stedronsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Protein Polymer Technologies Inc
Original Assignee
Protein Polymer Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Protein Polymer Technologies Inc filed Critical Protein Polymer Technologies Inc
Application granted granted Critical
Publication of DE69534373D1 publication Critical patent/DE69534373D1/de
Publication of DE69534373T2 publication Critical patent/DE69534373T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DE69534373T 1994-11-21 1995-09-29 Chemische veränderung von repetitiven polymeren zur erhöhung der wasserlöslichkeit Expired - Lifetime DE69534373T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US343264 1994-11-21
US08/343,264 US5760004A (en) 1994-11-21 1994-11-21 Chemical modification of repetitive polymers to enhance water solubility
PCT/US1995/012959 WO1996016168A1 (en) 1994-11-21 1995-09-29 Chemical modification of repetitive polymers to enhance water solubility

Publications (2)

Publication Number Publication Date
DE69534373D1 true DE69534373D1 (de) 2005-09-15
DE69534373T2 DE69534373T2 (de) 2006-05-24

Family

ID=23345377

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69534373T Expired - Lifetime DE69534373T2 (de) 1994-11-21 1995-09-29 Chemische veränderung von repetitiven polymeren zur erhöhung der wasserlöslichkeit

Country Status (8)

Country Link
US (2) US5760004A (de)
EP (1) EP0792357B1 (de)
JP (1) JP3121019B2 (de)
AT (1) ATE301711T1 (de)
AU (1) AU697605B2 (de)
CA (1) CA2205219A1 (de)
DE (1) DE69534373T2 (de)
WO (1) WO1996016168A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010021513A1 (en) * 1991-11-21 2001-09-13 Puijk Wouter Cornelis Test device comprising a plate containing a multiplicity of wells with an associated metering device, as well as a kit which comprises these devices and use of the devices
JP2002281964A (ja) * 2000-12-26 2002-10-02 Sanyo Chem Ind Ltd 細胞生産方法
US7004945B2 (en) 2001-11-01 2006-02-28 Spinewave, Inc. Devices and methods for the restoration of a spinal disc
WO2003037165A2 (en) * 2001-11-01 2003-05-08 Boyd Lawrence M System and method for the pretreatment of the endplates of an intervertebral disc
US8298606B2 (en) * 2002-03-08 2012-10-30 The Regents Of The University Of California Methods and compositions for stabilizing the myocardium
US7985601B2 (en) * 2002-03-08 2011-07-26 The Regents Of The University Of California Tunable, semi-interpenetrating polymer networks (sIPNS) for medicine and biotechnology
DE60335798D1 (de) * 2002-05-20 2011-03-03 Danisco Us Inc Synthese von anorganischen strukturen unter verwendung von templates und katalyse durch selbstangeordnete repeat-protein-polymere
US20040132978A1 (en) * 2002-11-12 2004-07-08 Fahnestock Stephen R. Method for purifying and recovering silk proteins in soluble form and uses thereof
JP2004206910A (ja) * 2002-12-24 2004-07-22 Sumitomo Wiring Syst Ltd ヒューズコネクタ
US7060260B2 (en) * 2003-02-20 2006-06-13 E.I. Du Pont De Nemours And Company Water-soluble silk proteins in compositions for skin care, hair care or hair coloring
US20050142094A1 (en) * 2003-03-12 2005-06-30 Manoj Kumar Use of repeat sequence protein polymers in personal care compositions
US7297678B2 (en) * 2003-03-12 2007-11-20 Genencor International, Inc. Use of repeat sequence protein polymers in personal care compositions
JP4850709B2 (ja) * 2003-05-14 2012-01-11 ダニスコ・ユーエス・インコーポレーテッド 反復配列タンパク質ポリマーを使用する、活性剤の制御放出
WO2004104020A2 (en) * 2003-05-14 2004-12-02 Dow Corning Corporation Repeat sequence protein polymer active agent conjugates, methods and uses
TWI232934B (en) * 2003-11-19 2005-05-21 Ind Tech Res Inst A biochip containing splitable reaction confinement and method for producing same and application thereof
US7789913B2 (en) 2004-06-29 2010-09-07 Spine Wave, Inc. Methods for injecting a curable biomaterial into an intervertebral space
EP1869169A4 (de) * 2005-03-29 2015-11-04 Univ California Regelung des bestimmungsortes von stammzellen mit abstimmbaren netzen
EP2636415B1 (de) 2010-11-04 2019-12-25 Sanyo Chemical Industries, Ltd. Zelladhäsionsmaterial für biologisches gewebe
US9700425B1 (en) 2011-03-20 2017-07-11 Nuvasive, Inc. Vertebral body replacement and insertion methods
EP3182985B1 (de) 2014-08-20 2020-01-08 Silk Technologies Ltd. Aus fibroin gewonnene proteinzusammensetzung
EP3226835A4 (de) 2014-12-02 2018-09-26 Silk Therapeutics, Inc. Funktionskleidungsstück aus seide sowie produkte und verfahren zur herstellung davon
EP3322434A4 (de) 2015-07-14 2019-01-09 Silk Therapeutics Inc. Funktionsbekleidung und -produkte aus seide und verfahren zur herstellung davon
CN109640694A (zh) 2016-04-08 2019-04-16 康奈尔大学 使用丝衍生蛋白质增强伤口愈合的方法
SG11201901137UA (en) 2016-08-12 2019-03-28 Silk Technologies Ltd Silk-derived protein for treating inflammation
CN111712514A (zh) 2017-09-27 2020-09-25 自然进化公司 丝涂布织物和产品及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2000951A1 (de) * 1968-01-30 1969-09-19 Kyowa Hakko Kogyo Kk
FR2063335A5 (en) * 1969-10-03 1971-07-09 Allemand Claude Proteins esterified with epoxides for cos-metics
US4224219A (en) * 1978-11-15 1980-09-23 Anheuser-Busch, Incorporated Method for producing water soluble corn protein derivatives by reacting with alkylene oxide
US5243038A (en) * 1986-11-04 1993-09-07 Protein Polymer Technologies, Inc. Construction of synthetic DNA and its use in large polypeptide synthesis
EP0406357B1 (de) * 1988-11-09 1998-01-07 Protein Polymer Technologies, Inc. Funktionelles, durch ein rekombinantes verfahren hergestelltes synthetisches proteinpolymer
DE4016002A1 (de) * 1990-05-18 1991-11-21 Basf Ag Verwendung von wasserloeslichen oder wasserdispergierbaren gepfropften proteinen als zusatz zu wasch- und reinigungsmitteln

Also Published As

Publication number Publication date
EP0792357A4 (de) 1999-05-19
DE69534373T2 (de) 2006-05-24
ATE301711T1 (de) 2005-08-15
US6034220A (en) 2000-03-07
EP0792357B1 (de) 2005-08-10
JPH10500701A (ja) 1998-01-20
AU3891595A (en) 1996-06-17
US5760004A (en) 1998-06-02
AU697605B2 (en) 1998-10-15
WO1996016168A1 (en) 1996-05-30
CA2205219A1 (en) 1996-05-30
JP3121019B2 (ja) 2000-12-25
EP0792357A1 (de) 1997-09-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee
8370 Indication related to discontinuation of the patent is to be deleted