DE69534776D1 - Klonierung und expression von einer acetylcholin-durchlässigen ionenkanälen rezeptor-untereinheit - Google Patents

Klonierung und expression von einer acetylcholin-durchlässigen ionenkanälen rezeptor-untereinheit

Info

Publication number
DE69534776D1
DE69534776D1 DE69534776T DE69534776T DE69534776D1 DE 69534776 D1 DE69534776 D1 DE 69534776D1 DE 69534776 T DE69534776 T DE 69534776T DE 69534776 T DE69534776 T DE 69534776T DE 69534776 D1 DE69534776 D1 DE 69534776D1
Authority
DE
Germany
Prior art keywords
subunit
nicotinic acetylcholine
alpha9
acetylcholine
receptors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69534776T
Other languages
English (en)
Other versions
DE69534776T2 (de
Inventor
Ana Belen Elgoyhen
David S Johnson
James Richard Boulter
Stephen Fox Heinemann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Salk Institute for Biological Studies
Original Assignee
Salk Institute for Biological Studies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salk Institute for Biological Studies filed Critical Salk Institute for Biological Studies
Application granted granted Critical
Publication of DE69534776D1 publication Critical patent/DE69534776D1/de
Publication of DE69534776T2 publication Critical patent/DE69534776T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
DE69534776T 1994-07-21 1995-07-18 Klonierung und expression von einer acetylcholin-durchlässigen ionenkanälen rezeptor-untereinheit Expired - Lifetime DE69534776T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/278,635 US5683912A (en) 1994-07-21 1994-07-21 Cloning and expression of a novel acetylcholine-gated ion channel receptor subunit
US278635 1994-07-21
PCT/US1995/009104 WO1996003504A1 (en) 1994-07-21 1995-07-18 Cloning and expression of an acetylcholine-gated ion channel receptor subunit

Publications (2)

Publication Number Publication Date
DE69534776D1 true DE69534776D1 (de) 2006-04-20
DE69534776T2 DE69534776T2 (de) 2006-10-12

Family

ID=23065747

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69534776T Expired - Lifetime DE69534776T2 (de) 1994-07-21 1995-07-18 Klonierung und expression von einer acetylcholin-durchlässigen ionenkanälen rezeptor-untereinheit

Country Status (7)

Country Link
US (4) US5683912A (de)
EP (1) EP0765391B1 (de)
JP (1) JPH10503091A (de)
AT (1) ATE317434T1 (de)
CA (1) CA2192694C (de)
DE (1) DE69534776T2 (de)
WO (1) WO1996003504A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19819829A1 (de) * 1998-05-04 1999-11-11 Bayer Ag Nukleinsäuren, die für Acetylcholinrezeptor-Untereinheiten von Insekten kodieren
DE19850429A1 (de) * 1998-10-27 2000-05-04 Andre Schrattenholz Fragmente
US6252132B1 (en) * 1998-11-02 2001-06-26 Institut Pasteur Mutant mouse containing a knockout mutation in DNA encoding an endogenous alpha 4 subunit of nicotinic acetylcholine receptor
WO2000035274A1 (en) * 1998-12-17 2000-06-22 The Johns Hopkins University School Of Medicine Olfactory receptor expression libraries and methods of making and using them
US6197580B1 (en) * 1999-02-01 2001-03-06 American Home Products Corporation Transcriptional regulation of the human β3-adrenergic receptor gene
IL148667A0 (en) * 1999-09-15 2002-09-12 Janssen Pharmaceutica Nv Nicotinic acetylcholine receptor
EP1090991A1 (de) 1999-09-29 2001-04-11 Sanofi-Synthelabo Nikotin-acetylcholin-Rezeptor, dessen Isolierung und Verwendung
DE10042177A1 (de) * 2000-08-28 2002-03-14 Bayer Ag Acetylcholinrezeptor-Untereinheiten
FR2813499B1 (fr) * 2000-09-04 2004-11-26 Pasteur Institut Mammifere non-humain mutant pour l'expression de la sous- unite alpha6 du recepteur nicotinique de l'acetylcholine et utilisation pour le criblage de substances susceptibles d'interagir avec ce recepteur
EP1190709A1 (de) * 2000-09-21 2002-03-27 Tinnitus Forschungs- und Entwicklungs GmbH Behandlung von Tinnitus
EP1190708A1 (de) * 2000-09-21 2002-03-27 Tinnitus Forschungs- und Entwicklungs GmbH Medizinische Verwendung von Verbindungen
US7491385B2 (en) * 2001-09-05 2009-02-17 Genegrafts Ltd. Nucleic acid constructs and cells, and methods utilizing same for modifying the electrophysiological function of excitable tissues
US7294333B1 (en) * 2000-10-20 2007-11-13 Genegrafts Ltd. Nucleic acid constructs and cells, and methods utilizing same for modifying the electrophysiological function of excitable tissues
US20030051266A1 (en) * 2001-02-14 2003-03-13 Serafini Tito Andrew Collections of transgenic animal lines (living library)
US7563595B2 (en) * 2002-11-08 2009-07-21 University Of South Florida Nucleic acids encoding functional splice variants of the α7 nicotinic acetylcholine receptor subunit and methods for producing the encoded proteins
US20050170360A1 (en) * 2004-01-30 2005-08-04 Papke Roger L. Variant neuronal nicotinic alpha-7 receptor and methods of use
WO2006091672A2 (en) * 2005-02-23 2006-08-31 Dow Agrosciences Llc Novel assays utilizing nicotinic acetylcholine receptor subunits
US7879913B2 (en) * 2005-06-28 2011-02-01 Catholic Healthcare West Iptakalim hydrochloride for decreasing nicotine use
US20080112927A1 (en) * 2006-10-23 2008-05-15 Genegrafts Ltd. Cells and methods utilizing same for modifying the electrophysiological function of excitable tissues
US9005981B2 (en) * 2008-12-30 2015-04-14 Dow Agrosciences Llc Assays utilizing nicotinic acetylcholine receptor subunits
NZ600278A (en) 2009-11-13 2014-04-30 Grifols Therapeutics Inc Von willebrand factor (vwf)-containing preparations, and methods, kits, and uses related thereto

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341554C (en) * 1988-03-18 2007-10-09 The Salk Institute For Biological Studies Neuronal nicotinic acetylcholine receptor compositions and assay
US5369028A (en) * 1990-04-03 1994-11-29 The Salk Institute Biotechnology/Industrial Associates, Inc. DNA and mRNA encoding human neuronal nicotinic acetylcholine receptor compositions and cells transformed with same

Also Published As

Publication number Publication date
EP0765391A1 (de) 1997-04-02
US6646109B1 (en) 2003-11-11
DE69534776T2 (de) 2006-10-12
EP0765391B1 (de) 2006-02-08
ATE317434T1 (de) 2006-02-15
US6100046A (en) 2000-08-08
CA2192694A1 (en) 1996-02-08
WO1996003504A1 (en) 1996-02-08
JPH10503091A (ja) 1998-03-24
US6013766A (en) 2000-01-11
CA2192694C (en) 2010-09-21
US5683912A (en) 1997-11-04

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