DE69535556D1 - Zusammensetzungen, vorrichtung und verfahren zur elektrotransport-wirkstoffabgabe - Google Patents

Zusammensetzungen, vorrichtung und verfahren zur elektrotransport-wirkstoffabgabe

Info

Publication number
DE69535556D1
DE69535556D1 DE69535556T DE69535556T DE69535556D1 DE 69535556 D1 DE69535556 D1 DE 69535556D1 DE 69535556 T DE69535556 T DE 69535556T DE 69535556 T DE69535556 T DE 69535556T DE 69535556 D1 DE69535556 D1 DE 69535556D1
Authority
DE
Germany
Prior art keywords
electrotransport
composition
body surface
compositions
active substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69535556T
Other languages
English (en)
Other versions
DE69535556T2 (de
Inventor
James A Huntington
Michel Cormier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of DE69535556D1 publication Critical patent/DE69535556D1/de
Publication of DE69535556T2 publication Critical patent/DE69535556T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Electrotherapy Devices (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Centrifugal Separators (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
DE69535556T 1994-11-14 1995-11-01 Zusammensetzungen, vorrichtung und verfahren zur elektrotransport-wirkstoffabgabe Expired - Lifetime DE69535556T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US338924 1994-11-14
US08/338,924 US5736580A (en) 1994-11-14 1994-11-14 Composition, device, and method for electrotransport agent delivery
PCT/US1995/014091 WO1996014869A1 (en) 1994-11-14 1995-11-01 Composition, device, and method for electrotransport agent delivery

Publications (2)

Publication Number Publication Date
DE69535556D1 true DE69535556D1 (de) 2007-09-20
DE69535556T2 DE69535556T2 (de) 2008-03-06

Family

ID=23326715

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69535556T Expired - Lifetime DE69535556T2 (de) 1994-11-14 1995-11-01 Zusammensetzungen, vorrichtung und verfahren zur elektrotransport-wirkstoffabgabe

Country Status (11)

Country Link
US (3) US5736580A (de)
EP (1) EP0789589B1 (de)
JP (1) JP4049389B2 (de)
AT (1) ATE369150T1 (de)
CA (1) CA2201725C (de)
DE (1) DE69535556T2 (de)
DK (1) DK0789589T3 (de)
ES (1) ES2292171T3 (de)
HK (1) HK1000450A1 (de)
PT (1) PT789589E (de)
WO (1) WO1996014869A1 (de)

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US6956032B1 (en) * 1986-04-18 2005-10-18 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
US8321013B2 (en) * 1996-01-08 2012-11-27 Impulse Dynamics, N.V. Electrical muscle controller and pacing with hemodynamic enhancement
US8825152B2 (en) 1996-01-08 2014-09-02 Impulse Dynamics, N.V. Modulation of intracellular calcium concentration using non-excitatory electrical signals applied to the tissue
US9289618B1 (en) 1996-01-08 2016-03-22 Impulse Dynamics Nv Electrical muscle controller
US7167748B2 (en) 1996-01-08 2007-01-23 Impulse Dynamics Nv Electrical muscle controller
JP4175662B2 (ja) 1996-01-08 2008-11-05 インパルス ダイナミクス エヌ．ヴイ． 電気的筋肉制御装置
US9713723B2 (en) 1996-01-11 2017-07-25 Impulse Dynamics Nv Signal delivery through the right ventricular septum
US5676648A (en) 1996-05-08 1997-10-14 The Aps Organization, Llp Iontophoretic drug delivery apparatus and method for use
US6385487B1 (en) 1996-05-08 2002-05-07 Biophoretic Therapeutic Systems, Llc Methods for electrokinetic delivery of medicaments
US6119036A (en) * 1997-03-26 2000-09-12 The Board Of Regents Of The University Of Oklahoma Iontophoretic transdermal delivery device
ATE373957T1 (de) 1997-10-09 2007-10-15 Univ Emory Verfahren und vorrichtung zur transdermalen verabreichung von lithium
EP0922467A3 (de) * 1997-12-12 2000-05-24 Takeda Chemical Industries, Ltd. Iontophoretische Verabreichung von Medikamenten
USRE37796E1 (en) 1997-12-16 2002-07-23 Biophoretic Therapeutic Systems, Llc Methods for iontophoretic delivery of antiviral agents
US6374136B1 (en) * 1997-12-22 2002-04-16 Alza Corporation Anhydrous drug reservoir for electrolytic transdermal delivery device
US6148231A (en) * 1998-09-15 2000-11-14 Biophoretic Therapeutic Systems, Llc Iontophoretic drug delivery electrodes and method
US9101765B2 (en) 1999-03-05 2015-08-11 Metacure Limited Non-immediate effects of therapy
US8019421B2 (en) * 1999-03-05 2011-09-13 Metacure Limited Blood glucose level control
WO2006073671A1 (en) 2004-12-09 2006-07-13 Impulse Dynamics Nv Protein activity modification
US8666495B2 (en) 1999-03-05 2014-03-04 Metacure Limited Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar
US8700161B2 (en) 1999-03-05 2014-04-15 Metacure Limited Blood glucose level control
US6477410B1 (en) * 2000-05-31 2002-11-05 Biophoretic Therapeutic Systems, Llc Electrokinetic delivery of medicaments
US7127285B2 (en) * 1999-03-12 2006-10-24 Transport Pharmaceuticals Inc. Systems and methods for electrokinetic delivery of a substance
US6792306B2 (en) 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
DE19923427A1 (de) * 1999-05-21 2000-11-23 Lohmann Therapie Syst Lts Vorrichtung und Verfahren zur Steigerung der transdermalen Permeation von Arzneistoffen
US7092753B2 (en) * 1999-06-04 2006-08-15 Impulse Dynamics Nv Drug delivery device
US7171263B2 (en) * 1999-06-04 2007-01-30 Impulse Dynamics Nv Drug delivery device
US7190997B1 (en) 1999-06-04 2007-03-13 Impulse Dynamics Nv Drug delivery device
US7069226B1 (en) 1999-07-07 2006-06-27 Synetic, Incorporated Prescription data processing system for determining new therapy starts
JP4879433B2 (ja) * 2000-01-13 2012-02-22 エミスフェアー・テクノロジーズ・インク 活性剤を送達するための化合物および組成物
GB0017999D0 (en) 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
CA2500713C (en) * 2002-10-04 2012-07-03 Photokinetix, Inc. Photokinetic delivery of biologically active substances using pulsed incoherent light
JP2006519663A (ja) 2003-03-10 2006-08-31 インパルス ダイナミックス エヌヴイ 心臓組織内の遺伝子発現を調節するための電気信号を送出する装置及び方法
US11439815B2 (en) 2003-03-10 2022-09-13 Impulse Dynamics Nv Protein activity modification
US8792985B2 (en) 2003-07-21 2014-07-29 Metacure Limited Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar
US8352031B2 (en) 2004-03-10 2013-01-08 Impulse Dynamics Nv Protein activity modification
US11779768B2 (en) 2004-03-10 2023-10-10 Impulse Dynamics Nv Protein activity modification
US8296162B1 (en) 2005-02-01 2012-10-23 Webmd Llc. Systems, devices, and methods for providing healthcare information
WO2006097934A2 (en) 2005-03-18 2006-09-21 Metacure Limited Pancreas lead
EP1898991B1 (de) 2005-05-04 2016-06-29 Impulse Dynamics NV Proteinaktivitätsmodifizierung
US8380530B2 (en) * 2007-02-02 2013-02-19 Webmd Llc. Personalized health records with associative relationships
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
US20090137925A1 (en) * 2007-11-23 2009-05-28 Divya Cantor Impedance Spectroscopy Cervix Scanning Apparatus and Method
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
WO2011046927A1 (en) * 2009-10-13 2011-04-21 Nupathe,Inc. Transdermal methods and systems for the delivery of rizatriptan
US8934975B2 (en) 2010-02-01 2015-01-13 Metacure Limited Gastrointestinal electrical therapy
JP6243102B2 (ja) * 2012-05-01 2017-12-06 株式会社ジェムインターナショナル 貼付剤

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US5084241A (en) * 1982-09-20 1992-01-28 V-Tech, Inc. Apparatus including a sample petter tube for obtaining reproducible liquid samples of small volume
US5128376A (en) * 1983-07-01 1992-07-07 Nitto Denko Corporation Method for percutaneously administering physiologically active agents using an adjuvant a solvent and a diol moderator
US4605670A (en) * 1984-02-01 1986-08-12 Nitto Electric Industrial Co., Ltd. Method for percutaneously administering metoclopramide
US4722720A (en) * 1985-04-30 1988-02-02 Nhk Spring Co., Ltd. Tension providing device
US4722726A (en) * 1986-02-12 1988-02-02 Key Pharmaceuticals, Inc. Method and apparatus for iontophoretic drug delivery
DE3724691C2 (de) * 1987-07-25 1999-03-18 Konrad Minninger Pharmazeutisches Mittel zur lokalen Therapie von schuppenden Hautkrankheiten
ATE91079T1 (de) * 1989-01-25 1993-07-15 Wolff Chem Pharm Gmbh Salicylsaeurehaltiges mittel gegen schuppende hauterkrankungen.
US5087242A (en) * 1989-07-21 1992-02-11 Iomed, Inc. Hydratable bioelectrode
US5023085A (en) * 1989-11-29 1991-06-11 Pfizer Inc. Transdermal flux enhancers in combination with iontophoresis in topical administration of pharmaceuticals
US5149719A (en) * 1990-04-27 1992-09-22 Minnesota Mining And Manufacturing Company Composition for transdermal penetration of medicaments
US5087241A (en) * 1990-07-24 1992-02-11 Empi, Inc. Iontophoresis electrode with reservoir and injection site
ES2072134T3 (es) * 1990-10-29 1995-07-01 Alza Corp Electrodo iontoforetico para suministrar farmacos y metodo para su hidratacion.
US5158537A (en) * 1990-10-29 1992-10-27 Alza Corporation Iontophoretic delivery device and method of hydrating same
ATE169826T1 (de) * 1992-01-21 1998-09-15 Macrochem Corp Iontophoretische verbesserte verabreichung von medikamenten
US5310404A (en) * 1992-06-01 1994-05-10 Alza Corporation Iontophoretic delivery device and method of hydrating same
JPH0616538A (ja) * 1992-07-03 1994-01-25 Japan Tobacco Inc イオントフォレーゼのための薬物吸収用液組成物

Also Published As

Publication number Publication date
PT789589E (pt) 2007-08-31
DK0789589T3 (da) 2007-12-17
CA2201725C (en) 2008-06-03
JPH10508849A (ja) 1998-09-02
WO1996014869A1 (en) 1996-05-23
ES2292171T3 (es) 2008-03-01
ATE369150T1 (de) 2007-08-15
US5736580A (en) 1998-04-07
CA2201725A1 (en) 1996-05-23
DE69535556T2 (de) 2008-03-06
JP4049389B2 (ja) 2008-02-20
EP0789589B1 (de) 2007-08-08
US5811465A (en) 1998-09-22
US6057374A (en) 2000-05-02
HK1000450A1 (en) 2008-04-03
EP0789589A1 (de) 1997-08-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition