DE69605901T2 - Zentrifugiersystem zm intermittierenden sammeln von mononuklearen zellen - Google Patents
Zentrifugiersystem zm intermittierenden sammeln von mononuklearen zellenInfo
- Publication number
- DE69605901T2 DE69605901T2 DE69605901T DE69605901T DE69605901T2 DE 69605901 T2 DE69605901 T2 DE 69605901T2 DE 69605901 T DE69605901 T DE 69605901T DE 69605901 T DE69605901 T DE 69605901T DE 69605901 T2 DE69605901 T2 DE 69605901T2
- Authority
- DE
- Germany
- Prior art keywords
- mononuclear cells
- intermittent collection
- centrifuging system
- centrifuging
- intermittent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
- B04B2005/045—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation having annular separation channels
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/422,597 US5704888A (en) | 1995-04-14 | 1995-04-14 | Intermittent collection of mononuclear cells in a centrifuge apparatus |
PCT/US1996/005144 WO1996032198A1 (en) | 1995-04-14 | 1996-04-12 | Centrifuged system for intermittent collection of mononuclear cells |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69605901D1 DE69605901D1 (de) | 2000-02-03 |
DE69605901T2 true DE69605901T2 (de) | 2000-05-04 |
Family
ID=23675570
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69605901T Expired - Lifetime DE69605901T2 (de) | 1995-04-14 | 1996-04-12 | Zentrifugiersystem zm intermittierenden sammeln von mononuklearen zellen |
Country Status (5)
Country | Link |
---|---|
US (2) | US5704888A (de) |
EP (1) | EP0817680B1 (de) |
JP (1) | JP4580470B2 (de) |
DE (1) | DE69605901T2 (de) |
WO (1) | WO1996032198A1 (de) |
Families Citing this family (43)
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---|---|---|---|---|
US5573678A (en) * | 1987-01-30 | 1996-11-12 | Baxter International Inc. | Blood processing systems and methods for collecting mono nuclear cells |
US5961842A (en) * | 1995-06-07 | 1999-10-05 | Baxter International Inc. | Systems and methods for collecting mononuclear cells employing control of packed red blood cell hematocrit |
US6027441A (en) | 1997-07-01 | 2000-02-22 | Baxter International Inc. | Systems and methods providing a liquid-primed, single flow access chamber |
US5980760A (en) * | 1997-07-01 | 1999-11-09 | Baxter International Inc. | System and methods for harvesting mononuclear cells by recirculation of packed red blood cells |
US6027657A (en) * | 1997-07-01 | 2000-02-22 | Baxter International Inc. | Systems and methods for collecting diluted mononuclear cells |
US6334842B1 (en) | 1999-03-16 | 2002-01-01 | Gambro, Inc. | Centrifugal separation apparatus and method for separating fluid components |
US6348156B1 (en) | 1999-09-03 | 2002-02-19 | Baxter International Inc. | Blood processing systems and methods with sensors to detect contamination due to presence of cellular components or dilution due to presence of plasma |
US6294094B1 (en) | 1999-09-03 | 2001-09-25 | Baxter International Inc. | Systems and methods for sensing red blood cell hematocrit |
US6284142B1 (en) | 1999-09-03 | 2001-09-04 | Baxter International Inc. | Sensing systems and methods for differentiating between different cellular blood species during extracorporeal blood separation or processing |
US6524231B1 (en) * | 1999-09-03 | 2003-02-25 | Baxter International Inc. | Blood separation chamber with constricted interior channel and recessed passage |
US7011761B2 (en) * | 1999-09-03 | 2006-03-14 | Baxter International Inc. | Red blood cell processing systems and methods which control red blood cell hematocrit |
US7947236B2 (en) | 1999-12-03 | 2011-05-24 | Becton, Dickinson And Company | Device for separating components of a fluid sample |
US6354986B1 (en) | 2000-02-16 | 2002-03-12 | Gambro, Inc. | Reverse-flow chamber purging during centrifugal separation |
JP4382322B2 (ja) * | 2000-03-09 | 2009-12-09 | カリディアンビーシーティ、インコーポレイテッド | 体外血液処理装置 |
EP1363739B1 (de) | 2000-11-02 | 2011-12-21 | CaridianBCT, Inc. | Vorrichtungen, systeme und verfahren zur fluidtrennung |
US6579219B2 (en) * | 2001-04-09 | 2003-06-17 | Medtronic, Inc. | Centrifuge bag and methods of use |
JP2004536794A (ja) * | 2001-04-09 | 2004-12-09 | メドトロニック、インコーポレイテッド | マイクロ遠心機を用いる血液成分の分離方法及びその使用法 |
US6890291B2 (en) * | 2001-06-25 | 2005-05-10 | Mission Medical, Inc. | Integrated automatic blood collection and processing unit |
US6878105B2 (en) * | 2001-08-16 | 2005-04-12 | Baxter International Inc. | Red blood cell processing systems and methods with deliberate under spill of red blood cells |
US20030173274A1 (en) * | 2002-02-01 | 2003-09-18 | Frank Corbin | Blood component separation device, system, and method including filtration |
DE10306534B4 (de) * | 2002-02-17 | 2012-04-12 | Schober Meditec Gmbh | Vorrichtung zur Steigerung der katalytischen Aktivität von Enzymen durch Emission von Induktions- und Licht- Signalen |
EP1494735B1 (de) | 2002-04-16 | 2008-01-02 | Gambro BCT, Inc. | System und verfahren zur aufarbeitung von blutbestandteilen |
WO2003089926A2 (en) | 2002-04-19 | 2003-10-30 | Mission Medical, Inc. | Integrated automatic blood processing unit |
US7297272B2 (en) * | 2002-10-24 | 2007-11-20 | Fenwal, Inc. | Separation apparatus and method |
US7354515B2 (en) | 2004-02-23 | 2008-04-08 | Millennium Medical Technologies, Inc. | Fluid concentrator |
US7087177B2 (en) * | 2004-04-16 | 2006-08-08 | Baxter International Inc. | Methods for determining flow rates of biological fluids |
US20060226086A1 (en) * | 2005-04-08 | 2006-10-12 | Robinson Thomas C | Centrifuge for blood processing systems |
US8075468B2 (en) * | 2008-02-27 | 2011-12-13 | Fenwal, Inc. | Systems and methods for mid-processing calculation of blood composition |
US8685258B2 (en) * | 2008-02-27 | 2014-04-01 | Fenwal, Inc. | Systems and methods for conveying multiple blood components to a recipient |
EP2517793B1 (de) | 2008-07-21 | 2013-09-11 | Becton, Dickinson and Company | Dichtephasentrennvorrichtung |
MX2011000794A (es) | 2008-07-21 | 2011-02-24 | Becton Dickinson Co | Dispositivo de separacion de fase por densidad. |
ES2430638T3 (es) | 2008-07-21 | 2013-11-21 | Becton, Dickinson And Company | Dispositivo de separación de fases por densidad |
NZ596537A (en) | 2009-05-15 | 2014-11-28 | Becton Dickinson Co | Density phase separation device |
US8870733B2 (en) * | 2010-11-19 | 2014-10-28 | Kensey Nash Corporation | Centrifuge |
US9011684B2 (en) | 2011-03-07 | 2015-04-21 | Spinesmith Holdings, Llc | Fluid concentrator with removable cartridge |
MX354547B (es) | 2011-11-14 | 2018-03-09 | Alfasigma Spa | Ensayos y métodos para seleccionar un regimen de tratamiento para un sujeto con depresión. |
EP2664383A1 (de) * | 2012-05-15 | 2013-11-20 | Miltenyi Biotec GmbH | Zentrifugationskammer mit Deflektorabschirmungen |
WO2014127122A1 (en) | 2013-02-18 | 2014-08-21 | Terumo Bct, Inc. | System for blood separation with a separation chamber having an internal gravity valve |
US20150017714A1 (en) | 2013-07-02 | 2015-01-15 | Miltenyi Biotec Gmbh | Centrifugation chamber with gas permeable membrane layers for cell cultivation |
EP2821145B1 (de) * | 2013-07-02 | 2019-08-21 | Miltenyi Biotec GmbH | Zentrifugierkammer mit gasdurchlässigen Membranschichten für Zellkultur |
EP2821144A1 (de) * | 2013-07-02 | 2015-01-07 | Miltenyi Biotec GmbH | Zentrifugierkammer mit gasdurchlässiger Membran für Zellkultur |
US9694359B2 (en) | 2014-11-13 | 2017-07-04 | Becton, Dickinson And Company | Mechanical separator for a biological fluid |
US9833557B2 (en) | 2014-12-19 | 2017-12-05 | Fenwal, Inc. | Systems and methods for determining free plasma hemoglobin |
Family Cites Families (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1723212A (en) * | 1925-11-30 | 1929-08-06 | Fostoria Serum Company | Process of clarifying liquids |
US3452924A (en) * | 1965-02-03 | 1969-07-01 | Sorvall Inc Ivan | System and method for washing blood and the like |
US3655123A (en) * | 1966-08-08 | 1972-04-11 | Us Health Education & Welfare | Continuous flow blood separator |
BE754683A (fr) * | 1969-08-11 | 1971-01-18 | Aga Ab | Recipient destine a contenir du sang |
US3724747A (en) * | 1971-03-15 | 1973-04-03 | Aga Ab | Centrifuge apparatus with means for moving material |
US3737096A (en) * | 1971-12-23 | 1973-06-05 | Ibm | Blood processing control apparatus |
US4934995A (en) * | 1977-08-12 | 1990-06-19 | Baxter International Inc. | Blood component centrifuge having collapsible inner liner |
US3858795A (en) * | 1973-02-08 | 1975-01-07 | Int Equipment Co | Method for washing blood cells |
US4007871A (en) * | 1975-11-13 | 1977-02-15 | International Business Machines Corporation | Centrifuge fluid container |
US4010894A (en) * | 1975-11-21 | 1977-03-08 | International Business Machines Corporation | Centrifuge fluid container |
US4636193A (en) * | 1976-05-14 | 1987-01-13 | Baxter Travenol Laboratories, Inc. | Disposable centrifugal blood processing system |
US4091989A (en) * | 1977-01-04 | 1978-05-30 | Schlutz Charles A | Continuous flow fractionation and separation device and method |
US4120844A (en) * | 1977-03-09 | 1978-10-17 | Ford Motor Company | Molded calcium carbonate filled propylene resin composites |
US4430072A (en) * | 1977-06-03 | 1984-02-07 | International Business Machines Corporation | Centrifuge assembly |
US4120448A (en) * | 1977-06-08 | 1978-10-17 | Baxter Travenol Laboratories, Inc. | Centrifugal liquid processing apparatus with automatically positioned collection port |
US4094461A (en) * | 1977-06-27 | 1978-06-13 | International Business Machines Corporation | Centrifuge collecting chamber |
US4356958A (en) * | 1977-07-19 | 1982-11-02 | The United States Of America As Represented By The Secretary Of Health And Human Services | Blood cell separator |
US5006103A (en) * | 1977-08-12 | 1991-04-09 | Baxter International Inc. | Disposable container for a centrifuge |
US4387848A (en) * | 1977-10-03 | 1983-06-14 | International Business Machines Corporation | Centrifuge assembly |
US4151844A (en) * | 1977-11-11 | 1979-05-01 | Baxter Travenol Laboratories, Inc. | Method and apparatus for separating whole blood into its components and for automatically collecting one component |
US4386730A (en) * | 1978-07-21 | 1983-06-07 | International Business Machines Corporation | Centrifuge assembly |
US4187979A (en) * | 1978-09-21 | 1980-02-12 | Baxter Travenol Laboratories, Inc. | Method and system for fractionating a quantity of blood into the components thereof |
DE2948177A1 (de) * | 1979-11-30 | 1981-06-04 | Dr. Eduard Fresenius Chemisch-Pharmazeutische Industrie Kg Apparatebau Kg, 6380 Bad Homburg | Separator fuer eine ultrazentrifuge |
US4316576A (en) * | 1980-11-06 | 1982-02-23 | Baxter Travenol Laboratories, Inc. | Method and chamber for separating granulocytes from whole blood |
US4531932A (en) * | 1981-11-27 | 1985-07-30 | Dideco S.P.A. | Centrifugal plasmapheresis device |
US4447221A (en) * | 1982-06-15 | 1984-05-08 | International Business Machines Corporation | Continuous flow centrifuge assembly |
DE3301113C2 (de) * | 1983-01-14 | 1985-01-10 | Fresenius AG, 6380 Bad Homburg | Verfahren und Vorrichtung für das Separieren von Medien |
US4807676A (en) * | 1985-02-26 | 1989-02-28 | Baxter International Inc. | Fluid transfer workstation |
US4647279A (en) * | 1985-10-18 | 1987-03-03 | Cobe Laboratories, Inc. | Centrifugal separator |
US4708712A (en) * | 1986-03-28 | 1987-11-24 | Cobe Laboratories, Inc. | Continuous-loop centrifugal separator |
US4668214A (en) * | 1986-06-09 | 1987-05-26 | Electromedics, Inc. | Method of washing red blood cells |
US5104526A (en) * | 1987-01-30 | 1992-04-14 | Baxter International Inc. | Centrifugation system having an interface detection system |
US4940543A (en) * | 1987-01-30 | 1990-07-10 | Baxter International Inc. | Plasma collection set |
US4838852A (en) * | 1987-03-27 | 1989-06-13 | Therakos, Inc. | Active specific immune suppression |
US4850995A (en) * | 1987-08-19 | 1989-07-25 | Cobe Laboratories, Inc. | Centrifugal separation of blood |
US5224921A (en) * | 1990-05-31 | 1993-07-06 | Baxter International Inc. | Small volume collection chamber |
US5141486B1 (en) * | 1990-11-05 | 1996-01-30 | Cobe Lab | Washing cells |
DE4129516C2 (de) * | 1991-09-06 | 2000-03-09 | Fresenius Ag | Verfahren und Vorrichtung zum Trennen von Blut in seine Bestandteile |
DE4132965A1 (de) * | 1991-10-04 | 1993-04-08 | Fresenius Ag | Vorrichtung zur trennung von medien in deren bestandteile |
WO1993012805A1 (en) * | 1992-01-02 | 1993-07-08 | Regents Of The University Of Michigan | Methods for regulatory lineages of human hematopoietic cells |
EP0618832B1 (de) * | 1992-10-22 | 1997-05-02 | Baxter International Inc. | Blutverarbeitungssysteme mit verbesserter ausbeute und methoden zur herstellung von vortexströmungsbedingungen |
DE69425966T2 (de) * | 1993-04-27 | 2001-03-29 | Haemonetics Corp | Apheresisgerät |
US5437598A (en) * | 1994-01-21 | 1995-08-01 | Cobe Laboratories, Inc. | Automation of plasma sequestration |
-
1995
- 1995-04-14 US US08/422,597 patent/US5704888A/en not_active Expired - Lifetime
-
1996
- 1996-04-12 DE DE69605901T patent/DE69605901T2/de not_active Expired - Lifetime
- 1996-04-12 JP JP53124696A patent/JP4580470B2/ja not_active Expired - Fee Related
- 1996-04-12 WO PCT/US1996/005144 patent/WO1996032198A1/en active IP Right Grant
- 1996-04-12 EP EP96911756A patent/EP0817680B1/de not_active Expired - Lifetime
-
1997
- 1997-06-09 US US08/871,207 patent/US5879280A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP4580470B2 (ja) | 2010-11-10 |
WO1996032198A1 (en) | 1996-10-17 |
JPH11503664A (ja) | 1999-03-30 |
EP0817680B1 (de) | 1999-12-29 |
US5704888A (en) | 1998-01-06 |
EP0817680A1 (de) | 1998-01-14 |
US5879280A (en) | 1999-03-09 |
DE69605901D1 (de) | 2000-02-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: GAMBRO INC., LAKEWOOD, COL., US |
|
8327 | Change in the person/name/address of the patent owner |
Owner name: GAMBRO BCT, INC., LAKEWOOD, COL., US |
|
8328 | Change in the person/name/address of the agent |
Representative=s name: SCHWABE, SANDMAIR, MARX, 81677 MUENCHEN |
|
8327 | Change in the person/name/address of the patent owner |
Owner name: CARIDIANBCT, INC., LAKEWOOD, COL., US |
|
R082 | Change of representative |
Ref document number: 817680 Country of ref document: EP Representative=s name: SCHWABE SANDMAIR MARX, DE |