DE69605901T2 - Zentrifugiersystem zm intermittierenden sammeln von mononuklearen zellen - Google Patents

Zentrifugiersystem zm intermittierenden sammeln von mononuklearen zellen

Info

Publication number
DE69605901T2
DE69605901T2 DE69605901T DE69605901T DE69605901T2 DE 69605901 T2 DE69605901 T2 DE 69605901T2 DE 69605901 T DE69605901 T DE 69605901T DE 69605901 T DE69605901 T DE 69605901T DE 69605901 T2 DE69605901 T2 DE 69605901T2
Authority
DE
Germany
Prior art keywords
mononuclear cells
intermittent collection
centrifuging system
centrifuging
intermittent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69605901T
Other languages
English (en)
Other versions
DE69605901D1 (de
Inventor
Dennis Hlavinka
Thomas Felt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terumo BCT Inc
Original Assignee
Cobe Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cobe Laboratories Inc filed Critical Cobe Laboratories Inc
Application granted granted Critical
Publication of DE69605901D1 publication Critical patent/DE69605901D1/de
Publication of DE69605901T2 publication Critical patent/DE69605901T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/045Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation having annular separation channels
DE69605901T 1995-04-14 1996-04-12 Zentrifugiersystem zm intermittierenden sammeln von mononuklearen zellen Expired - Lifetime DE69605901T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/422,597 US5704888A (en) 1995-04-14 1995-04-14 Intermittent collection of mononuclear cells in a centrifuge apparatus
PCT/US1996/005144 WO1996032198A1 (en) 1995-04-14 1996-04-12 Centrifuged system for intermittent collection of mononuclear cells

Publications (2)

Publication Number Publication Date
DE69605901D1 DE69605901D1 (de) 2000-02-03
DE69605901T2 true DE69605901T2 (de) 2000-05-04

Family

ID=23675570

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69605901T Expired - Lifetime DE69605901T2 (de) 1995-04-14 1996-04-12 Zentrifugiersystem zm intermittierenden sammeln von mononuklearen zellen

Country Status (5)

Country Link
US (2) US5704888A (de)
EP (1) EP0817680B1 (de)
JP (1) JP4580470B2 (de)
DE (1) DE69605901T2 (de)
WO (1) WO1996032198A1 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5573678A (en) * 1987-01-30 1996-11-12 Baxter International Inc. Blood processing systems and methods for collecting mono nuclear cells
US5961842A (en) * 1995-06-07 1999-10-05 Baxter International Inc. Systems and methods for collecting mononuclear cells employing control of packed red blood cell hematocrit
US6027441A (en) 1997-07-01 2000-02-22 Baxter International Inc. Systems and methods providing a liquid-primed, single flow access chamber
US5980760A (en) * 1997-07-01 1999-11-09 Baxter International Inc. System and methods for harvesting mononuclear cells by recirculation of packed red blood cells
US6027657A (en) * 1997-07-01 2000-02-22 Baxter International Inc. Systems and methods for collecting diluted mononuclear cells
US6334842B1 (en) 1999-03-16 2002-01-01 Gambro, Inc. Centrifugal separation apparatus and method for separating fluid components
US6348156B1 (en) 1999-09-03 2002-02-19 Baxter International Inc. Blood processing systems and methods with sensors to detect contamination due to presence of cellular components or dilution due to presence of plasma
US6294094B1 (en) 1999-09-03 2001-09-25 Baxter International Inc. Systems and methods for sensing red blood cell hematocrit
US6284142B1 (en) 1999-09-03 2001-09-04 Baxter International Inc. Sensing systems and methods for differentiating between different cellular blood species during extracorporeal blood separation or processing
US6524231B1 (en) * 1999-09-03 2003-02-25 Baxter International Inc. Blood separation chamber with constricted interior channel and recessed passage
US7011761B2 (en) * 1999-09-03 2006-03-14 Baxter International Inc. Red blood cell processing systems and methods which control red blood cell hematocrit
US7947236B2 (en) 1999-12-03 2011-05-24 Becton, Dickinson And Company Device for separating components of a fluid sample
US6354986B1 (en) 2000-02-16 2002-03-12 Gambro, Inc. Reverse-flow chamber purging during centrifugal separation
JP4382322B2 (ja) * 2000-03-09 2009-12-09 カリディアンビーシーティ、インコーポレイテッド 体外血液処理装置
EP1363739B1 (de) 2000-11-02 2011-12-21 CaridianBCT, Inc. Vorrichtungen, systeme und verfahren zur fluidtrennung
US6579219B2 (en) * 2001-04-09 2003-06-17 Medtronic, Inc. Centrifuge bag and methods of use
JP2004536794A (ja) * 2001-04-09 2004-12-09 メドトロニック、インコーポレイテッド マイクロ遠心機を用いる血液成分の分離方法及びその使用法
US6890291B2 (en) * 2001-06-25 2005-05-10 Mission Medical, Inc. Integrated automatic blood collection and processing unit
US6878105B2 (en) * 2001-08-16 2005-04-12 Baxter International Inc. Red blood cell processing systems and methods with deliberate under spill of red blood cells
US20030173274A1 (en) * 2002-02-01 2003-09-18 Frank Corbin Blood component separation device, system, and method including filtration
DE10306534B4 (de) * 2002-02-17 2012-04-12 Schober Meditec Gmbh Vorrichtung zur Steigerung der katalytischen Aktivität von Enzymen durch Emission von Induktions- und Licht- Signalen
EP1494735B1 (de) 2002-04-16 2008-01-02 Gambro BCT, Inc. System und verfahren zur aufarbeitung von blutbestandteilen
WO2003089926A2 (en) 2002-04-19 2003-10-30 Mission Medical, Inc. Integrated automatic blood processing unit
US7297272B2 (en) * 2002-10-24 2007-11-20 Fenwal, Inc. Separation apparatus and method
US7354515B2 (en) 2004-02-23 2008-04-08 Millennium Medical Technologies, Inc. Fluid concentrator
US7087177B2 (en) * 2004-04-16 2006-08-08 Baxter International Inc. Methods for determining flow rates of biological fluids
US20060226086A1 (en) * 2005-04-08 2006-10-12 Robinson Thomas C Centrifuge for blood processing systems
US8075468B2 (en) * 2008-02-27 2011-12-13 Fenwal, Inc. Systems and methods for mid-processing calculation of blood composition
US8685258B2 (en) * 2008-02-27 2014-04-01 Fenwal, Inc. Systems and methods for conveying multiple blood components to a recipient
EP2517793B1 (de) 2008-07-21 2013-09-11 Becton, Dickinson and Company Dichtephasentrennvorrichtung
MX2011000794A (es) 2008-07-21 2011-02-24 Becton Dickinson Co Dispositivo de separacion de fase por densidad.
ES2430638T3 (es) 2008-07-21 2013-11-21 Becton, Dickinson And Company Dispositivo de separación de fases por densidad
NZ596537A (en) 2009-05-15 2014-11-28 Becton Dickinson Co Density phase separation device
US8870733B2 (en) * 2010-11-19 2014-10-28 Kensey Nash Corporation Centrifuge
US9011684B2 (en) 2011-03-07 2015-04-21 Spinesmith Holdings, Llc Fluid concentrator with removable cartridge
MX354547B (es) 2011-11-14 2018-03-09 Alfasigma Spa Ensayos y métodos para seleccionar un regimen de tratamiento para un sujeto con depresión.
EP2664383A1 (de) * 2012-05-15 2013-11-20 Miltenyi Biotec GmbH Zentrifugationskammer mit Deflektorabschirmungen
WO2014127122A1 (en) 2013-02-18 2014-08-21 Terumo Bct, Inc. System for blood separation with a separation chamber having an internal gravity valve
US20150017714A1 (en) 2013-07-02 2015-01-15 Miltenyi Biotec Gmbh Centrifugation chamber with gas permeable membrane layers for cell cultivation
EP2821145B1 (de) * 2013-07-02 2019-08-21 Miltenyi Biotec GmbH Zentrifugierkammer mit gasdurchlässigen Membranschichten für Zellkultur
EP2821144A1 (de) * 2013-07-02 2015-01-07 Miltenyi Biotec GmbH Zentrifugierkammer mit gasdurchlässiger Membran für Zellkultur
US9694359B2 (en) 2014-11-13 2017-07-04 Becton, Dickinson And Company Mechanical separator for a biological fluid
US9833557B2 (en) 2014-12-19 2017-12-05 Fenwal, Inc. Systems and methods for determining free plasma hemoglobin

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1723212A (en) * 1925-11-30 1929-08-06 Fostoria Serum Company Process of clarifying liquids
US3452924A (en) * 1965-02-03 1969-07-01 Sorvall Inc Ivan System and method for washing blood and the like
US3655123A (en) * 1966-08-08 1972-04-11 Us Health Education & Welfare Continuous flow blood separator
BE754683A (fr) * 1969-08-11 1971-01-18 Aga Ab Recipient destine a contenir du sang
US3724747A (en) * 1971-03-15 1973-04-03 Aga Ab Centrifuge apparatus with means for moving material
US3737096A (en) * 1971-12-23 1973-06-05 Ibm Blood processing control apparatus
US4934995A (en) * 1977-08-12 1990-06-19 Baxter International Inc. Blood component centrifuge having collapsible inner liner
US3858795A (en) * 1973-02-08 1975-01-07 Int Equipment Co Method for washing blood cells
US4007871A (en) * 1975-11-13 1977-02-15 International Business Machines Corporation Centrifuge fluid container
US4010894A (en) * 1975-11-21 1977-03-08 International Business Machines Corporation Centrifuge fluid container
US4636193A (en) * 1976-05-14 1987-01-13 Baxter Travenol Laboratories, Inc. Disposable centrifugal blood processing system
US4091989A (en) * 1977-01-04 1978-05-30 Schlutz Charles A Continuous flow fractionation and separation device and method
US4120844A (en) * 1977-03-09 1978-10-17 Ford Motor Company Molded calcium carbonate filled propylene resin composites
US4430072A (en) * 1977-06-03 1984-02-07 International Business Machines Corporation Centrifuge assembly
US4120448A (en) * 1977-06-08 1978-10-17 Baxter Travenol Laboratories, Inc. Centrifugal liquid processing apparatus with automatically positioned collection port
US4094461A (en) * 1977-06-27 1978-06-13 International Business Machines Corporation Centrifuge collecting chamber
US4356958A (en) * 1977-07-19 1982-11-02 The United States Of America As Represented By The Secretary Of Health And Human Services Blood cell separator
US5006103A (en) * 1977-08-12 1991-04-09 Baxter International Inc. Disposable container for a centrifuge
US4387848A (en) * 1977-10-03 1983-06-14 International Business Machines Corporation Centrifuge assembly
US4151844A (en) * 1977-11-11 1979-05-01 Baxter Travenol Laboratories, Inc. Method and apparatus for separating whole blood into its components and for automatically collecting one component
US4386730A (en) * 1978-07-21 1983-06-07 International Business Machines Corporation Centrifuge assembly
US4187979A (en) * 1978-09-21 1980-02-12 Baxter Travenol Laboratories, Inc. Method and system for fractionating a quantity of blood into the components thereof
DE2948177A1 (de) * 1979-11-30 1981-06-04 Dr. Eduard Fresenius Chemisch-Pharmazeutische Industrie Kg Apparatebau Kg, 6380 Bad Homburg Separator fuer eine ultrazentrifuge
US4316576A (en) * 1980-11-06 1982-02-23 Baxter Travenol Laboratories, Inc. Method and chamber for separating granulocytes from whole blood
US4531932A (en) * 1981-11-27 1985-07-30 Dideco S.P.A. Centrifugal plasmapheresis device
US4447221A (en) * 1982-06-15 1984-05-08 International Business Machines Corporation Continuous flow centrifuge assembly
DE3301113C2 (de) * 1983-01-14 1985-01-10 Fresenius AG, 6380 Bad Homburg Verfahren und Vorrichtung für das Separieren von Medien
US4807676A (en) * 1985-02-26 1989-02-28 Baxter International Inc. Fluid transfer workstation
US4647279A (en) * 1985-10-18 1987-03-03 Cobe Laboratories, Inc. Centrifugal separator
US4708712A (en) * 1986-03-28 1987-11-24 Cobe Laboratories, Inc. Continuous-loop centrifugal separator
US4668214A (en) * 1986-06-09 1987-05-26 Electromedics, Inc. Method of washing red blood cells
US5104526A (en) * 1987-01-30 1992-04-14 Baxter International Inc. Centrifugation system having an interface detection system
US4940543A (en) * 1987-01-30 1990-07-10 Baxter International Inc. Plasma collection set
US4838852A (en) * 1987-03-27 1989-06-13 Therakos, Inc. Active specific immune suppression
US4850995A (en) * 1987-08-19 1989-07-25 Cobe Laboratories, Inc. Centrifugal separation of blood
US5224921A (en) * 1990-05-31 1993-07-06 Baxter International Inc. Small volume collection chamber
US5141486B1 (en) * 1990-11-05 1996-01-30 Cobe Lab Washing cells
DE4129516C2 (de) * 1991-09-06 2000-03-09 Fresenius Ag Verfahren und Vorrichtung zum Trennen von Blut in seine Bestandteile
DE4132965A1 (de) * 1991-10-04 1993-04-08 Fresenius Ag Vorrichtung zur trennung von medien in deren bestandteile
WO1993012805A1 (en) * 1992-01-02 1993-07-08 Regents Of The University Of Michigan Methods for regulatory lineages of human hematopoietic cells
EP0618832B1 (de) * 1992-10-22 1997-05-02 Baxter International Inc. Blutverarbeitungssysteme mit verbesserter ausbeute und methoden zur herstellung von vortexströmungsbedingungen
DE69425966T2 (de) * 1993-04-27 2001-03-29 Haemonetics Corp Apheresisgerät
US5437598A (en) * 1994-01-21 1995-08-01 Cobe Laboratories, Inc. Automation of plasma sequestration

Also Published As

Publication number Publication date
JP4580470B2 (ja) 2010-11-10
WO1996032198A1 (en) 1996-10-17
JPH11503664A (ja) 1999-03-30
EP0817680B1 (de) 1999-12-29
US5704888A (en) 1998-01-06
EP0817680A1 (de) 1998-01-14
US5879280A (en) 1999-03-09
DE69605901D1 (de) 2000-02-03

Similar Documents

Publication Publication Date Title
DE69605901D1 (de) Zentrifugiersystem zm intermittierenden sammeln von mononuklearen zellen
DE69604578T2 (de) Zentrifugiersystem zum überlaufsammeln von spärlich vorhandenen bestandteilen wie mononuklearen zellen
DE69626832T2 (de) Blutbehandlungssysteme und methoden zur gewinnung von mononuklearen zellen
DE69513203D1 (de) Batterie-anordnung von fotovoltaischen zellen und herstellungsverfahren
DE69721893D1 (de) Verfahren zur Abscheidung von Zellen aus Blut
DE69636843D1 (de) Nachweis von Nukleinsäure-Änderungen
DE69025089T2 (de) Elektrochemische Zellen
DE69434705D1 (de) Multiprozessorsystem und Verfahren zur Zusammensetzung von ATM Zellen
DE69622534T2 (de) Selbstgetriebene zentrifuge mit konischen trennwänden
MX163326A (es) Conjunto separador de baterias
DE69734511D1 (de) Antigene modulation von zellen
DE69627291D1 (de) Elektrodensystem
FI973583A (fi) Separaattorisysteemin hihnarakenne
DE69606428D1 (de) Semigeflutete bleiakkumulatorenzelle
DE29519209U1 (de) Batteriefach zur Aufnahme von Batteriezellen
DE59602409D1 (de) Elektrolytzelle
DE59604894D1 (de) Testsystem zur erfassung der aktivität von nk-zellen
DE3581505D1 (de) Differenzierung menschlicher zellen.
ATE208812T1 (de) Vermehrung von knochenmarksstützzellen
DE69601849T2 (de) Elektrochemisches Bearbeitungsverfahren
DE29510106U1 (de) Vorrichtung zur Dacheinbindung von Dachkollektoren
DE29520680U1 (de) Filterzelle
FI961467A0 (fi) Sähkökemiallinen menetelmä
KR970030458U (ko) 차량의 버튼식 워터 세퍼레이터
DE29515321U1 (de) Plasmapheresestation zur Gewinnung von humanem Blutplasma

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: GAMBRO INC., LAKEWOOD, COL., US

8327 Change in the person/name/address of the patent owner

Owner name: GAMBRO BCT, INC., LAKEWOOD, COL., US

8328 Change in the person/name/address of the agent

Representative=s name: SCHWABE, SANDMAIR, MARX, 81677 MUENCHEN

8327 Change in the person/name/address of the patent owner

Owner name: CARIDIANBCT, INC., LAKEWOOD, COL., US

R082 Change of representative

Ref document number: 817680

Country of ref document: EP

Representative=s name: SCHWABE SANDMAIR MARX, DE