DE69608437T2 - Bioreaktor - Google Patents

Bioreaktor

Info

Publication number
DE69608437T2
DE69608437T2 DE69608437T DE69608437T DE69608437T2 DE 69608437 T2 DE69608437 T2 DE 69608437T2 DE 69608437 T DE69608437 T DE 69608437T DE 69608437 T DE69608437 T DE 69608437T DE 69608437 T2 DE69608437 T2 DE 69608437T2
Authority
DE
Germany
Prior art keywords
bioreactor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69608437T
Other languages
English (en)
Other versions
DE69608437D1 (de
Inventor
Jean Kersten
Augustinus Bader
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organogenesis Inc
Original Assignee
Organogenesis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organogenesis Inc filed Critical Organogenesis Inc
Publication of DE69608437D1 publication Critical patent/DE69608437D1/de
Application granted granted Critical
Publication of DE69608437T2 publication Critical patent/DE69608437T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/24—Gas permeable parts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/34—Internal compartments or partitions
DE69608437T 1995-04-28 1996-04-22 Bioreaktor Expired - Fee Related DE69608437T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BE9500391A BE1009306A5 (fr) 1995-04-28 1995-04-28 Bioreacteur.
PCT/BE1996/000045 WO1996034087A1 (fr) 1995-04-28 1996-04-22 Bioreacteur

Publications (2)

Publication Number Publication Date
DE69608437D1 DE69608437D1 (de) 2000-06-21
DE69608437T2 true DE69608437T2 (de) 2000-10-19

Family

ID=3888948

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69608437T Expired - Fee Related DE69608437T2 (de) 1995-04-28 1996-04-22 Bioreaktor

Country Status (7)

Country Link
US (1) US6228607B1 (de)
EP (1) EP0822976B1 (de)
AU (1) AU5393796A (de)
BE (1) BE1009306A5 (de)
CA (1) CA2219643C (de)
DE (1) DE69608437T2 (de)
WO (1) WO1996034087A1 (de)

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CA2324208C (en) * 1998-03-18 2009-06-30 Massachusetts Institute Of Technology Vascularized perfused microtissue/micro-organ arrays
US7759113B2 (en) * 1999-04-30 2010-07-20 The General Hospital Corporation Fabrication of tissue lamina using microfabricated two-dimensional molds
WO2000078920A1 (en) * 1999-06-21 2000-12-28 The General Hospital Corporation Methods and devices for cell culturing and organ assist systems
ATE373079T1 (de) * 1999-06-21 2007-09-15 Gen Hospital Corp Zellkultursysteme und verfahren für einrichtungen zur organunterstützung
DE19932439C2 (de) * 1999-07-12 2002-06-13 Sefar Ag Rueschlikon Bioreaktor
WO2001007069A1 (en) 1999-07-22 2001-02-01 Organogenesis Inc. In vivo induction for enhanced function of isolated hepatocytes
US7776021B2 (en) * 2000-04-28 2010-08-17 The Charles Stark Draper Laboratory Micromachined bilayer unit for filtration of small molecules
US6455007B1 (en) * 2000-06-13 2002-09-24 Symyx Technologies, Inc. Apparatus and method for testing compositions in contact with a porous medium
EP1370638A2 (de) * 2000-09-15 2003-12-17 Shell Internationale Researchmaatschappij B.V. Bioreaktor
US6734000B2 (en) 2000-10-12 2004-05-11 Regents Of The University Of California Nanoporous silicon support containing macropores for use as a bioreactor
US20060270032A1 (en) * 2005-05-24 2006-11-30 The Regents Of The University Of California Microscale micropatterened engineered in vitro tissue
WO2003060061A1 (en) * 2001-12-21 2003-07-24 Organogenesis Inc. Chamber with adjustable volume for cell culture and organ assist
US20040120854A1 (en) * 2002-04-04 2004-06-24 Heath James R Silicon-wafer based devices and methods for analyzing biological material
US7160719B2 (en) 2002-06-07 2007-01-09 Mayo Foundation For Medical Education And Research Bioartificial liver system
DE10242078A1 (de) * 2002-09-09 2004-03-18 Saxonia Bio Tec Gmbh Faserkassette und modular aufgebautes Kassettensystem
US7390653B2 (en) * 2002-12-04 2008-06-24 Synthecon, Inc. Culture chamber for biologicals
ATE439039T1 (de) 2003-01-16 2009-08-15 Gen Hospital Corp Verwendung von dreidimensionalen, mikrogefertigten, mittels gewebetechnologie hergestellten systemen für pharmakologische anwendungen
WO2005034624A2 (en) 2003-05-21 2005-04-21 The General Hospital Corporation Microfabricated compositions and processes for engineering tissues containing multiple cell types
DE10326747B4 (de) * 2003-06-13 2006-11-02 Gerlach, Jörg, Dr.med. Perfusionseinheit und Perfusionsstation zur Hautwundbehandlung sowie dessen Verwendung
CN103173354B (zh) * 2003-10-08 2017-07-14 威尔森沃尔夫制造公司 利用透气性材料进行细胞培养的方法及装置
AU2004229070A1 (en) * 2003-11-13 2005-06-02 Dale C. Gyure Novel bioreactor
US8318479B2 (en) 2004-05-19 2012-11-27 Massachusetts Institute Of Technology Perfused three-dimensional cell/tissue disease models
US7745209B2 (en) 2005-07-26 2010-06-29 Corning Incorporated Multilayered cell culture apparatus
EP1913126B1 (de) 2005-08-12 2019-09-25 Clemson University Research Foundation Kokultur-bioreaktor-system
US7682822B2 (en) * 2006-03-31 2010-03-23 Aastrom Biosciences, Inc. Ex vivo generated tissue system
US9057044B2 (en) 2006-08-30 2015-06-16 Meir Israelowitz Laminar flow reactor
EP2092052B1 (de) * 2006-12-07 2020-09-23 Wilson Wolf Manufacturing Corporation Hocheffiziente glasdurchlässige vorrichtungen zur zellkultivierung
US8528745B2 (en) 2007-04-20 2013-09-10 General Electric Company Membrane supported biofilm apparatus
US9309491B2 (en) * 2007-05-29 2016-04-12 Corning Incorporated Cell culture apparatus for co-culture of cells
US20080305539A1 (en) * 2007-06-08 2008-12-11 Robert Hickey Membrane supported bioreactor for conversion of syngas components to liquid products
WO2009042768A1 (en) * 2007-09-25 2009-04-02 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Triggerably dissolvable hollow fibers for controlled delivery
WO2009108654A2 (en) * 2008-02-25 2009-09-03 Clemson University Differential pressure pump system
GB0808373D0 (en) * 2008-05-09 2008-06-18 Synexa Life Sciences Pty Ltd Scalable cell culture bioreactor and cell culture process
WO2010006055A2 (en) * 2008-07-08 2010-01-14 Wilson Wolf Manufacturing Corporation Improved gas permeable cell culture device and method of use
AU2009308354A1 (en) * 2008-10-22 2010-04-29 Biovest International, Inc. Perfusion bioreactors, cell culture systems, and methods for production of cells and cell-derived products
US8713850B2 (en) * 2008-12-30 2014-05-06 H. Freeman Seebo Algae high density bioreactor
WO2010105204A2 (en) 2009-03-13 2010-09-16 Mayo Foundation For Medical Education And Research Bioartificial liver
US20110004304A1 (en) * 2009-03-20 2011-01-06 Tao Sarah L Culturing retinal cells and tissues
CN101549181B (zh) * 2009-05-07 2011-11-02 浙江大学 纳米纤维网片叠加式生物反应器
CN101559246B (zh) * 2009-05-26 2011-11-02 浙江大学 配备纳米纤维网片叠加式反应器的混合型人工肝支持系统
US8778669B2 (en) 2009-07-22 2014-07-15 Corning Incorporated Multilayer tissue culture vessel
US9725689B2 (en) 2010-10-08 2017-08-08 Terumo Bct, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
US9394369B2 (en) 2011-01-03 2016-07-19 The Regents Of The University Of California Luminescent porous silicon nanoparticles for targeted delivery and immunization
US20150017683A1 (en) * 2011-12-19 2015-01-15 Battelle Memorial Institute Stacked Membrane Bioreactor
US9005550B2 (en) 2012-10-29 2015-04-14 Corning Incorporated Multi-layered cell culture vessel with manifold grips
CN105992816B (zh) 2013-11-16 2018-04-17 泰尔茂比司特公司 生物反应器中的细胞扩增
EP3122866B1 (de) 2014-03-25 2019-11-20 Terumo BCT, Inc. Passives ersetzen von medien
EP3198006B1 (de) 2014-09-26 2021-03-24 Terumo BCT, Inc. Geplante fütterung
IL288852B2 (en) * 2015-06-23 2024-01-01 Univ Texas Methods and apparatus for growing cell populations for cell therapy
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US11702634B2 (en) 2017-03-31 2023-07-18 Terumo Bct, Inc. Expanding cells in a bioreactor
WO2018195014A1 (en) 2017-04-19 2018-10-25 Neubiser Richard Bioreactor for biological material
CN107287118A (zh) * 2017-08-22 2017-10-24 江苏健安生物科技有限公司 一种模块式细胞培养和运输组件

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3948732A (en) * 1973-05-31 1976-04-06 Instrumentation Laboratory, Inc. Cell culture assembly
US4537860A (en) * 1982-12-08 1985-08-27 Monsanto Company Static cell culture maintenance system
DE3471324D1 (en) * 1983-08-31 1988-06-23 Cell Environmental Syst Cell culture system
WO1989000188A1 (en) * 1987-06-30 1989-01-12 Brunswick Corporation Cell growth reactor with three compartments formed by hydrophobic and hydrophilic membranes
JPH0292270A (ja) * 1988-09-30 1990-04-03 Terumo Corp 細胞培養装置
CA2054210A1 (en) * 1989-05-05 1990-11-06 William R. Tolbert Cell culture system
GB8921458D0 (en) * 1989-09-22 1989-11-08 Univ Strathclyde Cell culture apparatus
FR2660323B1 (fr) * 1990-03-30 1992-07-24 Bertin & Cie Dispositif de culture cellulaire.
DE4206585C2 (de) * 1992-03-03 1994-11-24 Augustinus Dr Med Bader Vorrichtung zur Massenkultur von Zellen
DE4230194C2 (de) * 1992-09-09 1995-07-27 Joerg Dr Med Gerlach Reaktor zur Züchtung und zur Nutzung von Stoffwechselleistungen und/oder zum Erhalt von Mikroorganismen

Also Published As

Publication number Publication date
CA2219643A1 (fr) 1996-10-31
DE69608437D1 (de) 2000-06-21
US6228607B1 (en) 2001-05-08
EP0822976B1 (de) 2000-05-17
CA2219643C (fr) 2011-10-18
AU5393796A (en) 1996-11-18
BE1009306A5 (fr) 1997-02-04
WO1996034087A1 (fr) 1996-10-31
EP0822976A1 (de) 1998-02-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee