DE69619940T2 - Liganden des urokinaserezeptors - Google Patents

Liganden des urokinaserezeptors

Info

Publication number
DE69619940T2
DE69619940T2 DE69619940T DE69619940T DE69619940T2 DE 69619940 T2 DE69619940 T2 DE 69619940T2 DE 69619940 T DE69619940 T DE 69619940T DE 69619940 T DE69619940 T DE 69619940T DE 69619940 T2 DE69619940 T2 DE 69619940T2
Authority
DE
Germany
Prior art keywords
lower alkyl
halo
aryl
alkyl
cycloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69619940T
Other languages
English (en)
Other versions
DE69619940D1 (de
Inventor
Steve Rosenberg
L Spear
J Martin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Application granted granted Critical
Publication of DE69619940D1 publication Critical patent/DE69619940D1/de
Publication of DE69619940T2 publication Critical patent/DE69619940T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
DE69619940T 1995-06-07 1996-06-06 Liganden des urokinaserezeptors Expired - Fee Related DE69619940T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/485,021 US5747458A (en) 1995-06-07 1995-06-07 Urokinase receptor ligands
PCT/US1996/009648 WO1996040747A1 (en) 1995-06-07 1996-06-06 Urokinase receptor ligands

Publications (2)

Publication Number Publication Date
DE69619940D1 DE69619940D1 (de) 2002-04-25
DE69619940T2 true DE69619940T2 (de) 2002-12-19

Family

ID=23926620

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69619940T Expired - Fee Related DE69619940T2 (de) 1995-06-07 1996-06-06 Liganden des urokinaserezeptors

Country Status (14)

Country Link
US (2) US5747458A (de)
EP (1) EP0777680B1 (de)
JP (1) JPH10503784A (de)
AT (1) ATE214711T1 (de)
AU (1) AU6164096A (de)
BR (1) BR9606429A (de)
CA (1) CA2196334A1 (de)
DE (1) DE69619940T2 (de)
FI (1) FI970446A (de)
HU (1) HUP9702220A3 (de)
IL (1) IL120101A0 (de)
MX (1) MX9700888A (de)
NO (1) NO970513L (de)
WO (1) WO1996040747A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5519120A (en) * 1989-04-07 1996-05-21 Cancerforskningsfondet Af 1989 Urokinase-type plasminogen activator receptor antibodies
AU745839B2 (en) * 1997-07-31 2002-04-11 F. Hoffmann-La Roche Ag O-substituted hydroxycumaranone derivatives as antitumor and antimetastatic agents
US6458781B1 (en) 1998-04-27 2002-10-01 David Thomas Connor Substituted diarylalkyl amides as calcium channel antagonists
US6228985B1 (en) 1998-05-21 2001-05-08 Schering Corporation Derivatives of aminobenzoic and aminobiphenylcarboxylic acids useful as anti-cancer agents
ES2169690B1 (es) * 2000-10-06 2004-03-16 Diverdrugs Sl Trimeros de n-alquilglicina capaces de proteger a neuronas contra agresiones excitotoxicas, y composiciones que los contienen.
ES2169691B1 (es) * 2000-10-11 2004-03-16 Diverdrugs Sl Trimeros de n-alquilglicina capaces de bloquear la respuesta a sustancias quimicas, estimulos termicos o mediadores de la inflamacion de receptores neuronales, y composiciones que los contienen.
PL377856A1 (pl) * 2003-04-15 2006-02-20 Merck Patent Gmbh Identyfikacja trimerów N-alkiloglicyny dla wywoływania apoptozy
PT2611775E (pt) 2010-08-31 2016-06-07 Consejo Superior De Investig Científicas Agonistas dos recetores de neurotrofina e sua utilização como medicamentos
JP5641054B2 (ja) * 2010-12-03 2014-12-17 富士通株式会社 新規化合物、並びに、キネシンスピンドルタンパク質阻害剤及びその応用
IT202100023357A1 (it) 2021-09-09 2023-03-09 Cheirontech S R L Peptidi con attività anti-angiogenica

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708871A (en) * 1983-03-08 1987-11-24 Commonwealth Serum Laboratories Commission Antigenically active amino acid sequences
ATE81722T1 (de) * 1984-07-24 1992-11-15 Coselco Mimotopes Pty Ltd Verfahren zur bestimmung von mimotopen.
NZ215865A (en) * 1985-04-22 1988-10-28 Commw Serum Lab Commission Method of determining the active site of a receptor-binding analogue
IE66205B1 (en) * 1990-06-14 1995-12-13 Paul A Bartlett Polypeptide analogs
HUT72614A (en) * 1992-09-24 1996-05-28 Chiron Corp Synthesis of n-substituted oligomers
US5536853A (en) * 1994-04-11 1996-07-16 Chiron Corporation Opiate receptor ligands
RU2152954C1 (ru) * 1994-04-26 2000-07-20 Селектид Корпорейшн Ингибиторы фактора ха

Also Published As

Publication number Publication date
WO1996040747A1 (en) 1996-12-19
HUP9702220A3 (en) 1998-06-29
ATE214711T1 (de) 2002-04-15
EP0777680A1 (de) 1997-06-11
NO970513D0 (no) 1997-02-05
CA2196334A1 (en) 1996-12-19
US6121240A (en) 2000-09-19
FI970446A (fi) 1997-03-26
AU6164096A (en) 1996-12-30
BR9606429A (pt) 1997-09-02
EP0777680B1 (de) 2002-03-20
HUP9702220A2 (hu) 1998-05-28
MX9700888A (es) 1997-04-30
JPH10503784A (ja) 1998-04-07
IL120101A0 (en) 1997-04-15
NO970513L (no) 1997-02-05
DE69619940D1 (de) 2002-04-25
US5747458A (en) 1998-05-05
FI970446A0 (fi) 1997-02-03

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee