DE69623141D1 - Verwendung von Tomoxetin zur Behandlung von Hyperaktivität mit Aufmerksamkeitsstörungen - Google Patents

Verwendung von Tomoxetin zur Behandlung von Hyperaktivität mit Aufmerksamkeitsstörungen

Info

Publication number
DE69623141D1
DE69623141D1 DE69623141T DE69623141T DE69623141D1 DE 69623141 D1 DE69623141 D1 DE 69623141D1 DE 69623141 T DE69623141 T DE 69623141T DE 69623141 T DE69623141 T DE 69623141T DE 69623141 D1 DE69623141 D1 DE 69623141D1
Authority
DE
Germany
Prior art keywords
tomoxetine
attention deficit
treat hyperactivity
treat
hyperactivity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69623141T
Other languages
English (en)
Other versions
DE69623141T2 (de
Inventor
John Harrison Heiligenstein
Gary Dennis Tollefson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23463572&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69623141(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE69623141D1 publication Critical patent/DE69623141D1/de
Publication of DE69623141T2 publication Critical patent/DE69623141T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
DE69623141T 1995-01-11 1996-01-09 Verwendung von Tomoxetin zur Behandlung von Hyperaktivität mit Aufmerksamkeitsstörungen Expired - Lifetime DE69623141T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/371,341 US5658590A (en) 1995-01-11 1995-01-11 Treatment of attention-deficit/hyperactivity disorder

Publications (2)

Publication Number Publication Date
DE69623141D1 true DE69623141D1 (de) 2002-10-02
DE69623141T2 DE69623141T2 (de) 2003-04-24

Family

ID=23463572

Family Applications (2)

Application Number Title Priority Date Filing Date
DE200512000011 Active DE122005000011I2 (de) 1995-01-11 1996-01-09 Verwendung von Tomoxetin zur Behandlung von Hyperaktivit{t mit Aufmerksamkeitsst¦rungen
DE69623141T Expired - Lifetime DE69623141T2 (de) 1995-01-11 1996-01-09 Verwendung von Tomoxetin zur Behandlung von Hyperaktivität mit Aufmerksamkeitsstörungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE200512000011 Active DE122005000011I2 (de) 1995-01-11 1996-01-09 Verwendung von Tomoxetin zur Behandlung von Hyperaktivit{t mit Aufmerksamkeitsst¦rungen

Country Status (28)

Country Link
US (1) US5658590A (de)
EP (1) EP0721777B1 (de)
JP (2) JPH10512262A (de)
KR (1) KR19980701276A (de)
CN (2) CN1168095A (de)
AT (1) ATE222757T1 (de)
AU (1) AU688665B2 (de)
BR (1) BR9606903A (de)
CA (1) CA2209735C (de)
CZ (1) CZ292226B6 (de)
DE (2) DE122005000011I2 (de)
DK (1) DK0721777T3 (de)
ES (1) ES2181845T3 (de)
FI (1) FI119354B (de)
FR (1) FR10C0041I2 (de)
HU (1) HU227306B1 (de)
LU (1) LU91238I2 (de)
NL (1) NL300180I2 (de)
NO (1) NO317027B1 (de)
NZ (1) NZ301500A (de)
PL (1) PL187573B1 (de)
PT (1) PT721777E (de)
RO (1) RO118374B1 (de)
RU (1) RU2163802C2 (de)
SI (1) SI0721777T1 (de)
TR (1) TR199700627T1 (de)
UA (1) UA43385C2 (de)
WO (1) WO1996021430A1 (de)

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UA56257C2 (uk) * 1997-09-23 2003-05-15 Елі Ліллі Енд Компані Спосіб лікування неадекватної визивної поведінки
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US5902797A (en) * 1997-11-10 1999-05-11 Beth Israel Deaconess Medical Center Nutritional supplement for use in the treatment of attention deficit
KR20010034758A (ko) * 1998-04-09 2001-04-25 로렌스 티. 마이젠헬더 신경 장애의 신규 치료 방법
US6586427B2 (en) 1998-04-09 2003-07-01 Pharmacia & Upjohn Company Treatments for nervous disorders
WO2000027428A1 (en) * 1998-11-09 2000-05-18 Idec Pharmaceuticals Corporation Treatment of hematologic malignancies associated with circulating tumor cells using chimeric anti-cd20 antibody
US6419960B1 (en) 1998-12-17 2002-07-16 Euro-Celtique S.A. Controlled release formulations having rapid onset and rapid decline of effective plasma drug concentrations
US6898455B2 (en) * 1999-10-29 2005-05-24 The Mclean Hospital Corporation Method for providing optimal drug dosage
US6400978B1 (en) 1999-10-29 2002-06-04 The Mclean Hospital Corporation Method and apparatus for detecting mental disorders
PL357042A1 (en) * 2000-03-07 2004-07-12 Eli Lilly And Company Treatment of psoriasis
US20020016334A1 (en) * 2000-07-31 2002-02-07 Coe Jotham Wadsworth Pharmaceutical composition for the treatment of attention deficit hyperactivity disorder (ADHD)
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
US20040034106A1 (en) * 2001-11-06 2004-02-19 Read Holly Ann Treatment of anxiety disorders
CN1713900A (zh) * 2001-12-11 2005-12-28 伊莱利利公司 去甲肾上腺素再摄取抑制剂在治疗认知障碍中的应用
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WO2004017977A2 (en) 2002-08-23 2004-03-04 Eli Lilly And Company 2- (phenoxymethyl)- and 2- (phenylthiomethyl)-morpholine derivatives for use as selective norepinephrine reuptake inhibitors
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
WO2004103356A2 (en) * 2003-05-15 2004-12-02 Eli Lilly And Company Treatment of emotional dysregulation
US20060100290A1 (en) * 2003-07-28 2006-05-11 Dunaway Leslie J Treatment of allergic rhinitis and asthma
EP1660064A2 (de) * 2003-08-27 2006-05-31 Eli Lilly And Company Behandlung von lernstörungen und motorischen störungen mit norepinephrin-wiederaufnahme-hemmern
CA2536161A1 (en) * 2003-08-27 2005-03-10 Eli Lilly And Company Treatment of pervasive developmental disorders with norepinephrine reuptake inhibitors
CA2552064A1 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Atomoxetine formulations
US8545881B2 (en) 2004-04-19 2013-10-01 Eurand Pharmaceuticals, Ltd. Orally disintegrating tablets and methods of manufacture
BRPI0511529A (pt) * 2004-05-27 2008-01-02 Warner Lambert Co combinação terapêutica para distúrbios de hiperatividade/déficit de atenção
US7507861B2 (en) * 2004-06-28 2009-03-24 Teva Pharmaceutical Fine Chemicals, S.R.L. Process for the preparation of atomoxetine hydrochloride
US7439399B2 (en) * 2004-06-28 2008-10-21 Teva Pharmaceutical Fine Chemicals Processes for the preparation of atomoxetine hydrochloride
CA2568629A1 (en) * 2004-07-22 2006-02-23 Teva Pharmaceutical Fine Chemicals S.R.L. Polymorphs of atomoxetine hydrochloride
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
NZ589750A (en) 2004-10-21 2012-07-27 Aptalis Pharmatech Inc Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US7569729B2 (en) * 2005-04-05 2009-08-04 Teva Pharmaceutical Fine Chemicals S.R.L. Stable atomoxetine hydrochloride, a process for the preparation thereof, and an analytical control of its stability
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
AU2006318476A1 (en) * 2005-11-23 2007-05-31 Auspex Pharmaceuticals, Inc. Substituted aryloxypropylamines with serotoninergic and/or norepinephrinergic activity
EP1963268B1 (de) 2005-12-07 2010-12-01 NSAB, Filial af NeuroSearch Sweden AB, Sverige Disubstituierte phenylpiperidine als modulatoren der corticalen catecholaminergen neurotransmission
US20080020387A1 (en) * 2006-03-31 2008-01-24 Lawrence Donald G Biomarker-optimized adhd treatment
US20080146675A1 (en) * 2006-04-05 2008-06-19 Eugenio Castelli Stable Atomoxetine Hydrochloride, a process for the preparation thereof, and an analytical control of its stability
US20080031932A1 (en) * 2006-08-04 2008-02-07 Watson Laboratories, Inc. Transdermal atomoxetine formulations and associated methods
US20080145318A1 (en) * 2006-12-13 2008-06-19 Midha Kamal K Atomoxetine formulations and associated methods
WO2008122019A1 (en) * 2007-04-02 2008-10-09 Cypress Biosciences, Inc. Improving the tolerability of both mirtazapine and reboxetine by using them in combination
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JP5309262B2 (ja) 2009-12-02 2013-10-09 アプタリス ファーマ リミテッド フェキソフェナジン・マイクロカプセル及びそれを含む組成物
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US11241391B2 (en) 2011-03-23 2022-02-08 Ironshore Pharmaceuticals & Development, Inc. Compositions for treatment of attention deficit hyperactivity disorder
US8916588B2 (en) 2011-03-23 2014-12-23 Ironshore Pharmaceuticals & Development, Inc. Methods for treatment of attention deficit hyperactivity disorder
WO2012129551A1 (en) 2011-03-23 2012-09-27 Ironshore Pharmaceuticals & Development, Inc. Methods and compositions for treatment of attention deficit disorder
US10905652B2 (en) 2011-03-23 2021-02-02 Ironshore Pharmaceuticals & Development, Inc. Compositions for treatment of attention deficit hyperactivity disorder
US9603809B2 (en) 2011-03-23 2017-03-28 Ironshore Pharmaceuticals & Development, Inc. Methods of treatment of attention deficit hyperactivity disorder
US8927010B2 (en) 2011-03-23 2015-01-06 Ironshore Pharmaceuticals & Development, Inc. Compositions for treatment of attention deficit hyperactivity disorder
US10292937B2 (en) 2011-03-23 2019-05-21 Ironshore Pharmaceuticals & Development, Inc. Methods of treatment of attention deficit hyperactivity disorder
US9283214B2 (en) 2011-03-23 2016-03-15 Ironshore Pharmaceuticals & Development, Inc. Compositions for treatment of attention deficit hyperactivity disorder
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Also Published As

Publication number Publication date
TR199700627T1 (xx) 1998-01-21
KR19980701276A (ko) 1998-05-15
DE69623141T2 (de) 2003-04-24
HUP9801283A2 (hu) 1999-06-28
EP0721777B1 (de) 2002-08-28
NO317027B1 (no) 2004-07-26
CZ292226B6 (cs) 2003-08-13
RU2163802C2 (ru) 2001-03-10
CA2209735A1 (en) 1996-07-18
NO973170L (no) 1997-09-02
PT721777E (pt) 2002-11-29
CA2209735C (en) 2002-10-01
EP0721777A3 (de) 1997-03-05
FI119354B (fi) 2008-10-31
JP2005325139A (ja) 2005-11-24
DE122005000011I2 (de) 2006-02-09
HUP9801283A3 (en) 1999-09-28
RO118374B1 (ro) 2003-05-30
JPH10512262A (ja) 1998-11-24
PL187573B1 (pl) 2004-08-31
HU227306B1 (en) 2011-03-28
AU4693896A (en) 1996-07-31
FR10C0041I2 (de) 2011-04-29
NL300180I1 (nl) 2005-05-02
NZ301500A (en) 2000-07-28
DE122005000011I1 (de) 2005-06-23
BR9606903A (pt) 1997-10-21
PL321273A1 (en) 1997-11-24
MX9705117A (es) 1997-10-31
CN1168095A (zh) 1997-12-17
AU688665B2 (en) 1998-03-12
ATE222757T1 (de) 2002-09-15
FR10C0041I1 (de) 2010-10-15
NL300180I2 (nl) 2005-08-01
NO973170D0 (no) 1997-07-08
CZ214597A3 (cs) 1998-01-14
UA43385C2 (uk) 2001-12-17
DK0721777T3 (da) 2002-10-07
SI0721777T1 (en) 2003-02-28
EP0721777A2 (de) 1996-07-17
FI972922A (fi) 1997-07-09
WO1996021430A1 (en) 1996-07-18
ES2181845T3 (es) 2003-03-01
US5658590A (en) 1997-08-19
LU91238I2 (fr) 2006-07-03
FI972922A0 (fi) 1997-07-09
CN1781480A (zh) 2006-06-07

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Legal Events

Date Code Title Description
R071 Expiry of right

Free format text: PRODUCT NAME: ATOMOXETIN, GEGEBENENFALLS IN FORM EINES SALZES WIE DES HYDROCHLORIDS; NAT. REGISTRATION NO/DATE: 60775.00.00 60775.01.00 60775.02.00 60775.03.00 60775.04.00 60775.05.00 20041207 FIRST RL 00006/0379 20040527 EGISTRATION: GROSSBRITANNIEN PL 00006/0374 PL 00006/0375 PL 00006/0376 PL 00006/0377 PL 00006/0378 P

Spc suppl protection certif: 122005000011

Filing date: 20050312

Expiry date: 20160110

Extension date: 20190527