DE69624726D1 - Chitosan-impfstoff-zusammensetzungen zur intranasalen verabreichung und anwendungen - Google Patents

Chitosan-impfstoff-zusammensetzungen zur intranasalen verabreichung und anwendungen

Info

Publication number
DE69624726D1
DE69624726D1 DE69624726T DE69624726T DE69624726D1 DE 69624726 D1 DE69624726 D1 DE 69624726D1 DE 69624726 T DE69624726 T DE 69624726T DE 69624726 T DE69624726 T DE 69624726T DE 69624726 D1 DE69624726 D1 DE 69624726D1
Authority
DE
Germany
Prior art keywords
chitosan
intranasal administration
applications
vaccine compositions
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69624726T
Other languages
English (en)
Other versions
DE69624726T2 (de
Inventor
Lisbeth Illum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyowa Kirin Services Ltd
Original Assignee
West Pharmaceutical Services Drug Delivery and Clinical Research Center Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by West Pharmaceutical Services Drug Delivery and Clinical Research Center Ltd filed Critical West Pharmaceutical Services Drug Delivery and Clinical Research Center Ltd
Application granted granted Critical
Publication of DE69624726D1 publication Critical patent/DE69624726D1/de
Publication of DE69624726T2 publication Critical patent/DE69624726T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55583—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588—Adjuvants of undefined constitution
DE69624726T 1995-12-07 1996-12-09 Chitosan-impfstoff-zusammensetzungen zur intranasalen verabreichung und anwendungen Expired - Lifetime DE69624726T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9525083.3A GB9525083D0 (en) 1995-12-07 1995-12-07 Vaccine compositions
PCT/GB1996/003019 WO1997020576A1 (en) 1995-12-07 1996-12-09 Vaccine compositions for intranasal administration comprising chitosan and use thereof

Publications (2)

Publication Number Publication Date
DE69624726D1 true DE69624726D1 (de) 2002-12-12
DE69624726T2 DE69624726T2 (de) 2003-09-18

Family

ID=10785093

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69624726T Expired - Lifetime DE69624726T2 (de) 1995-12-07 1996-12-09 Chitosan-impfstoff-zusammensetzungen zur intranasalen verabreichung und anwendungen

Country Status (13)

Country Link
US (2) US6391318B1 (de)
EP (1) EP0865297B1 (de)
JP (1) JP4063876B2 (de)
AT (1) ATE227134T1 (de)
CA (1) CA2237529C (de)
DE (1) DE69624726T2 (de)
DK (1) DK0865297T3 (de)
ES (1) ES2186809T3 (de)
GB (2) GB9525083D0 (de)
NO (1) NO323084B1 (de)
NZ (1) NZ323973A (de)
PT (1) PT865297E (de)
WO (1) WO1997020576A1 (de)

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JP2005501845A (ja) 2001-08-16 2005-01-20 メディカル リサーチ カウンシル キチン微小粒子およびそれらの医学的用途
CN100333792C (zh) 2001-09-28 2007-08-29 南佛罗里达大学 Rsv基因表达疫苗
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RU2378008C2 (ru) * 2002-05-14 2010-01-10 Новартис Вэксинес Энд Дайэгностикс С.Р.Л. Комбинированные вакцины против бактериального менингита для введения через слизистую оболочку
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WO2004076664A2 (en) * 2003-02-21 2004-09-10 University Of South Florida Vectors for regulating gene expression
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US20040248804A1 (en) * 2003-05-01 2004-12-09 Khurshid Iqbal Nasal administration of the LH-RH analog Leuprolide
EP1631308B1 (de) 2003-05-30 2013-07-31 Amylin Pharmaceuticals, LLC Neue verfahren und zusammensetzungen für die verbesserte transmukosale abgabe von peptiden und proteinen
GB0315632D0 (en) * 2003-07-04 2003-08-13 West Pharm Serv Drug Res Ltd Pharmaceutical formulations
CA2548150A1 (en) 2003-12-04 2005-06-23 University Of South Florida Polynucleotides for reducing respiratory syncytial virus gene expression
US7968122B2 (en) * 2003-12-10 2011-06-28 Adventrx Pharmaceuticals, Inc. Anti-viral pharmaceutical compositions
US20050129679A1 (en) * 2003-12-15 2005-06-16 Nastech Pharmaceutical Company Inc. Method for opening tight junctions
US7740883B2 (en) * 2004-03-28 2010-06-22 University Of Debrecen Nanoparticles from chitosan
US20050281886A1 (en) * 2004-05-06 2005-12-22 Ivrea Pharmaceuticals, Inc. Particles for the delivery of active agents
US20090069226A1 (en) * 2004-05-28 2009-03-12 Amylin Pharmaceuticals, Inc. Transmucosal delivery of peptides and proteins
US20050283004A1 (en) 2004-06-18 2005-12-22 Hopax Chemicals Manufacturing Co., Ltd. Alkylsulfonated polyaminosaccharides
KR20070057932A (ko) * 2004-09-15 2007-06-07 오츠카 세이야쿠 가부시키가이샤 경점막용 조성물, 및 경점막 흡수의 향상 방법
US20070036867A1 (en) * 2005-05-23 2007-02-15 University Of South Florida Controlled and Sustained Gene Transfer Mediated by Thiol-Modified Polymers
US20070031512A1 (en) * 2005-08-03 2007-02-08 Amcol International Corporation Virus-interacting layered phyllosilicates and methods of inactivating viruses
US20100272769A1 (en) * 2005-08-03 2010-10-28 Amcol International Virus-, Bacteria-, and Fungi-Interacting Layered Phyllosilicates and Methods of Use
US20080184618A1 (en) * 2005-08-03 2008-08-07 Amcol International Virus-Interacting Layered Phyllosilicates and Methods of Use
US8536324B2 (en) * 2005-10-21 2013-09-17 University Of South Florida Method of drug delivery by carbon nanotube-chitosan nanocomplexes
CA2628313A1 (en) * 2005-11-04 2007-05-31 Bio Syntech Canada Inc. Composition and method for efficient delivery of nucleic acids to cells using chitosan
CA2635603C (en) 2005-11-30 2016-01-19 Endo Pharmaceuticals Inc. Treatment of xerostomia
NZ571965A (en) * 2006-03-30 2012-02-24 Engene Inc Chitosan-based nanoparticles and methods for transfecting gut cells in vivo
AU2007262845B2 (en) 2006-06-20 2013-07-25 Mucovax Inc. Compositions comprising chitin microparticles and their medical uses
PL2601970T3 (pl) 2006-09-29 2017-07-31 Takeda Vaccines, Inc. Preparaty szczepionki przeciw norowirusowi
EP2112923A1 (de) 2007-01-22 2009-11-04 Targacept Inc. Intranasale, orale und sublinguale verabreichung von metanikotin-analogen
US20080182819A1 (en) * 2007-01-29 2008-07-31 Act Iii Licensing, Llc Chitosan compositions and methods for using chitosan compositions in the treatment of health disorders
ATE530178T1 (de) 2007-05-23 2011-11-15 Amcol International Corp Mit cholesterin interagierende phyllosilikate und verfahren zur reduktion von hypercholesterinämie bei einem säuger
US20100266636A1 (en) * 2007-09-18 2010-10-21 Ligocyte Pharmaceuticals, Inc. Method of conferring a protective immune response to norovirus
KR20150129042A (ko) 2007-09-18 2015-11-18 다케다 백신즈 인코포레이티드 노로바이러스에 대한 보호면역반응을 제공하는 방법
EP2818178A1 (de) * 2008-01-11 2014-12-31 The Government of The United States of America as represented by The Secretary, Department of Health and Human Services Polypeptidimpfstoff und Impfstrategie gegen Mykobakterien
CN102014636A (zh) 2008-02-27 2011-04-13 安姆科尔国际公司 治疗和动脉粥样硬化有关的心血管障碍的方法
KR101793161B1 (ko) * 2008-08-08 2017-11-03 다케다 백신즈 인코포레이티드 강화된 교차 반응성을 가진 복합체 캡시드 아미노산 서열들을 포함하는 바이러스-유사 입자들
WO2010119112A1 (en) * 2009-04-15 2010-10-21 Ceva Sante Animale Recombinant avian herpes virus vectors and vaccine for immunizing waterfowl species
ES2926487T3 (es) 2011-07-11 2022-10-26 Takeda Vaccines Inc Formulaciones parenterales de vacunas de norovirus
ES2932952T3 (es) 2012-04-24 2023-01-30 Ohio State Innovation Foundation Composiciones y métodos para tratar y prevenir el síndrome reproductivo y respiratorio porcino
US10279028B2 (en) 2012-04-24 2019-05-07 Ohio State Innovation Foundation Compositions and methods for treating and preventing porcine reproductive and respiratory syndrome
CN108715607B (zh) * 2018-04-12 2021-12-10 华南农业大学 重组霍乱毒素b亚基蛋白、pedv灭活疫苗及制备与应用
CN109172817B (zh) * 2018-08-16 2021-10-26 华中农业大学 猪流行性腹泻病毒减毒活疫苗壳聚糖微球的制备方法及其应用
EP3698773A1 (de) 2019-02-21 2020-08-26 Università degli Studi di Parma Zusammensetzung und herstellung von pulvern mit nanoadjuvanzien zur mukosalen impfung

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Also Published As

Publication number Publication date
DE69624726T2 (de) 2003-09-18
JP2000501412A (ja) 2000-02-08
DK0865297T3 (da) 2003-03-03
ATE227134T1 (de) 2002-11-15
CA2237529C (en) 2008-10-14
CA2237529A1 (en) 1997-06-12
NO982497D0 (no) 1998-06-02
GB9525083D0 (en) 1996-02-07
GB2322801A (en) 1998-09-09
JP4063876B2 (ja) 2008-03-19
GB2322801B (en) 2000-01-19
PT865297E (pt) 2003-03-31
NO323084B1 (no) 2006-12-27
AU705452B2 (en) 1999-05-20
NZ323973A (en) 2004-12-24
US6391318B1 (en) 2002-05-21
NO982497L (no) 1998-06-02
GB9811810D0 (en) 1998-07-29
AU1102597A (en) 1997-06-27
US7323183B2 (en) 2008-01-29
EP0865297A1 (de) 1998-09-23
WO1997020576A1 (en) 1997-06-12
EP0865297B1 (de) 2002-11-06
ES2186809T3 (es) 2003-05-16
US20030039665A1 (en) 2003-02-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ARCHIMEDES DEVELOPMENT LTD., NOTTINGHAM, GB

8328 Change in the person/name/address of the agent

Representative=s name: STROHSCHAENK UND KOLLEGEN, 85521 OTTOBRUNN