DE69625483T2 - Transdermales pflaster zur verabreichung von 17-deacetyl norgestimat alleine oder in kombination mit einem östrogen - Google Patents

Transdermales pflaster zur verabreichung von 17-deacetyl norgestimat alleine oder in kombination mit einem östrogen

Info

Publication number
DE69625483T2
DE69625483T2 DE69625483T DE69625483T DE69625483T2 DE 69625483 T2 DE69625483 T2 DE 69625483T2 DE 69625483 T DE69625483 T DE 69625483T DE 69625483 T DE69625483 T DE 69625483T DE 69625483 T2 DE69625483 T2 DE 69625483T2
Authority
DE
Germany
Prior art keywords
estrogen
combination
alone
deacetyl
norgestimat
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69625483T
Other languages
English (en)
Other versions
DE69625483T3 (de
DE69625483D1 (de
Inventor
Janan Jona
Jay Audett
Noel Singh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
Ortho McNeil Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27044166&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69625483(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ortho McNeil Pharmaceutical Inc filed Critical Ortho McNeil Pharmaceutical Inc
Application granted granted Critical
Publication of DE69625483D1 publication Critical patent/DE69625483D1/de
Publication of DE69625483T2 publication Critical patent/DE69625483T2/de
Publication of DE69625483T3 publication Critical patent/DE69625483T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
DE69625483T 1995-06-07 1996-06-06 Transdermales pflaster zur verabreichung von 17-deacetyl norgestimat in kombination mit einem östrogen Expired - Lifetime DE69625483T3 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US473531 1990-02-01
US47353195A 1995-06-07 1995-06-07
US51726395A 1995-08-21 1995-08-21
US517263 1995-08-21
EP96921353A EP0836506B2 (de) 1995-06-07 1996-06-06 Transdermales pflaster zur verabreichung von 17-deacetyl norgestimat in kombination mit einem östrogen
PCT/US1996/009396 WO1996040355A1 (en) 1995-06-07 1996-06-06 Transdermal patch and method for administering 17-deacetyl norgestimate alone or in combination with an estrogen

Publications (3)

Publication Number Publication Date
DE69625483D1 DE69625483D1 (de) 2003-01-30
DE69625483T2 true DE69625483T2 (de) 2003-10-30
DE69625483T3 DE69625483T3 (de) 2012-05-10

Family

ID=27044166

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69625483T Expired - Lifetime DE69625483T3 (de) 1995-06-07 1996-06-06 Transdermales pflaster zur verabreichung von 17-deacetyl norgestimat in kombination mit einem östrogen

Country Status (22)

Country Link
US (3) US5876746A (de)
EP (1) EP0836506B2 (de)
JP (2) JP3534775B2 (de)
KR (1) KR100301226B1 (de)
CN (1) CN1188189C (de)
AT (1) ATE229828T1 (de)
AU (1) AU703593B2 (de)
CA (1) CA2222133C (de)
CZ (1) CZ292151B6 (de)
DE (1) DE69625483T3 (de)
DK (1) DK0836506T4 (de)
ES (1) ES2190472T5 (de)
HU (1) HU228434B1 (de)
IL (1) IL122432A (de)
MX (1) MX9709666A (de)
NO (1) NO316308B1 (de)
NZ (1) NZ311304A (de)
PL (1) PL181582B1 (de)
PT (1) PT836506E (de)
RU (1) RU2177311C2 (de)
UA (1) UA48973C2 (de)
WO (1) WO1996040355A1 (de)

Families Citing this family (178)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6407082B1 (en) * 1996-09-13 2002-06-18 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a vitamin D compound
DE19549264A1 (de) * 1995-12-23 1997-06-26 Schering Ag Verfahren und Kit zur Kontrazeption
US6511970B1 (en) 1996-09-13 2003-01-28 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium
US6034074A (en) 1996-09-13 2000-03-07 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a Vitamin D compound
US6028064A (en) 1996-09-13 2000-02-22 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of progestin products
US6765002B2 (en) 2000-03-21 2004-07-20 Gustavo Rodriguez Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium
US5939477A (en) * 1998-02-02 1999-08-17 Dow Corning Corporation Silicone pressure sensitive adhesive composition containing functionalized polyisobutylene
DE19814084B4 (de) * 1998-03-30 2005-12-22 Lts Lohmann Therapie-Systeme Ag D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung
DE19834007C1 (de) * 1998-07-29 2000-02-24 Lohmann Therapie Syst Lts Estradiolhaltiges Pflaster zur transdermalen Applikation von Hormonen und seine Verwendung
ES2379471T5 (es) † 1999-02-08 2015-05-26 Intarcia Therapeutics, Inc Vehículos viscosos biocompatibles de fase única no acuosos y procedimientos para su preparación
US7258869B1 (en) 1999-02-08 2007-08-21 Alza Corporation Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle
US6417227B1 (en) 1999-04-28 2002-07-09 Cg And Associates Methods of delivery of cetyl myristoleate
WO2001000116A1 (en) * 1999-06-25 2001-01-04 Schmidt Jonalee M Hairpiece and method for attaching same
DE19943317C1 (de) * 1999-09-10 2001-03-15 Lohmann Therapie Syst Lts Kunststofffolien, insbesondere für die Verwendung in einem dermalen oder transdermalen therapeutischen System und Verfahren zu ihrer Herstellung
JP4841781B2 (ja) * 1999-11-24 2011-12-21 アジル・セラピューティクス・インコーポレイテッド 改良された経皮的避妊薬送達系および方法
US7045145B1 (en) 1999-11-24 2006-05-16 Agile Therapeutics, Inc. Transdermal contraceptive delivery system and process
US7384650B2 (en) 1999-11-24 2008-06-10 Agile Therapeutics, Inc. Skin permeation enhancement composition for transdermal hormone delivery system
US6358939B1 (en) 1999-12-21 2002-03-19 Northern Lights Pharmaceuticals, Llc Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease
US6989377B2 (en) 1999-12-21 2006-01-24 Wisconsin Alumni Research Foundation Treating vitamin D responsive diseases
US7223418B2 (en) * 2000-03-07 2007-05-29 Tiejin Limited Stretchable patch
US20010044431A1 (en) * 2000-03-21 2001-11-22 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US7235397B1 (en) 2000-04-14 2007-06-26 Gensys, Inc. Methods and compositions for culturing spirochete and treating spirochetal diseases
USRE44145E1 (en) 2000-07-07 2013-04-09 A.V. Topchiev Institute Of Petrochemical Synthesis Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties
DE10041478A1 (de) * 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
US20040092494A9 (en) * 2000-08-30 2004-05-13 Dudley Robert E. Method of increasing testosterone and related steroid concentrations in women
US20040039356A1 (en) * 2000-10-16 2004-02-26 Masayoshi Maki Compositions for external preparations
US20020106402A1 (en) * 2000-12-05 2002-08-08 Hartwig Rod Lawson Crystallization inhibition of drugs in transdermal drug delivery systems and methods of use
US8840918B2 (en) * 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
US8206738B2 (en) 2001-05-01 2012-06-26 Corium International, Inc. Hydrogel compositions with an erodible backing member
US20050215727A1 (en) 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
US8728445B2 (en) 2001-05-01 2014-05-20 A.V. Topchiev Institute Of Petrochemical Synthesis, Russian Academy Of Sciences Hydrogel Compositions
US20050113510A1 (en) 2001-05-01 2005-05-26 Feldstein Mikhail M. Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components
DE60239528D1 (de) * 2001-05-01 2011-05-05 Corium International Redwood City Zweiphasige, wasserabsorbierende bioadhäsive zusammenstezung
US8541021B2 (en) 2001-05-01 2013-09-24 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions demonstrating phase separation on contact with aqueous media
US20030026830A1 (en) * 2001-05-08 2003-02-06 Thomas Lauterback Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine
US20030027793A1 (en) * 2001-05-08 2003-02-06 Thomas Lauterback Transdermal treatment of parkinson's disease
WO2003024450A1 (en) * 2001-09-20 2003-03-27 Eisai Co., Ltd. Methods for treating prion diseases
WO2003032914A2 (en) * 2001-10-17 2003-04-24 Eisai Co., Ltd. Methods for treating substance abuse with cholinesterase inhibitors
WO2003063927A2 (en) * 2001-11-16 2003-08-07 Eisai Co. Ltd Compositions and methods to treat gastrointestinal disorders
WO2003053221A2 (en) * 2001-12-19 2003-07-03 Eisai Co. Ltd Methods using proton pump inhibitors
CA2478336A1 (en) * 2002-03-11 2003-09-25 Janssen Pharmaceutica N.V. Extended cycle estrogen and sulfatase inhibiting progestogen contraceptive regimens
JP2005519962A (ja) * 2002-03-11 2005-07-07 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ スルファターゼを阻害する継続的プロゲストゲン避妊レジメン
JP2005519964A (ja) * 2002-03-11 2005-07-07 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ スルファターゼ阻害プロゲストゲンのみの避妊レジメン
US20030219471A1 (en) * 2002-03-11 2003-11-27 Caubel Patrick Michel Extended cycle estrogen and sulfatase inhibiting progestogen contraceptive regimens
ATE336252T1 (de) * 2002-03-11 2006-09-15 Janssen Pharmaceutica Nv Kontinuierliche sulfatase-hemmende progestogen enthaltende hormonsubstitutions-therapie
US7223386B2 (en) * 2002-03-11 2007-05-29 Dow Corning Corporation Preparations for topical skin use and treatment
US20040142914A1 (en) * 2002-03-11 2004-07-22 Friedman Andrew Joseph Extended transdermal contraceptive regimens
WO2003095623A2 (en) * 2002-05-10 2003-11-20 The Trustees Of Columbia University In The City Of New York Genetically engineered cell lines and systems for propagating varicella zoster virus and methods of use thereof
AU2003298514A1 (en) * 2002-05-17 2004-05-04 Eisai Co., Ltd. Methods and compositions using cholinesterase inhibitors
AU2003241464A1 (en) * 2002-05-17 2003-12-02 Eisai Co., Ltd. Compositions and methods using proton pump inhibitors
US20070053976A1 (en) * 2002-05-17 2007-03-08 Eisai R & D Management Co., Ltd. Novel combination of drugs as antidepressant
US20050245492A1 (en) 2004-04-28 2005-11-03 Lephart Edwin D Use of equol for treating skin diseases
US8668914B2 (en) 2002-07-24 2014-03-11 Brigham Young University Use of equol for treating skin diseases
DE10234673B4 (de) * 2002-07-30 2007-08-16 Schwarz Pharma Ag Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren
US8246980B2 (en) * 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system
US8211462B2 (en) * 2002-07-30 2012-07-03 Ucb Pharma Gmbh Hot-melt TTS for administering rotigotine
US8246979B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system for the administration of rotigotine
SI1426049T1 (en) * 2002-12-02 2005-08-31 Sanol Arznei Schwarz Gmbh Iontophoretic delivery of rotigotine for the treatment of Parkinson's disease
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
DE10261696A1 (de) 2002-12-30 2004-07-15 Schwarz Pharma Ag Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base
ME00147B (de) 2003-02-21 2010-10-10 Schering Ag Uv-stabiles transdermales pflaster
ATE487492T1 (de) * 2003-02-27 2010-11-15 Eisai R&D Man Co Ltd Pharmazeutische zusammensetzung zur behandlung von drogenabhängigkeit
HUP0301981A2 (hu) * 2003-06-30 2005-04-28 Richter Gedeon Vegyészeti Gyár Rt. Tiszta d-(17alfa)-13-etil-17-hidroxi-18,19-dinor-pregn-4-én-20-in-3-on-3E- és 3Z-oxim izomerek, valamint eljárás az izomer keverékek és a tiszta izomerek előállítására
HUP0301982A2 (hu) * 2003-06-30 2005-04-28 Richter Gedeon Vegyészeti Gyár Rt. Eljárás nagy tisztaságú d-(17alfa)-13-etil-17-hidroxi-18,19-dinor-pregn-4-én-20-in-3-on-oxim előállítására
US7816546B2 (en) 2003-06-30 2010-10-19 Richter Gedeon Vegyeszeti Gyar Rt. Process for the synthesis of high purity d-(17α)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-ene-20-yn-3-one-oxime
JP2007502831A (ja) * 2003-08-20 2007-02-15 ニトロメッド インコーポレーティッド ニトロソ化およびニトロシル化心血管化合物、組成物、ならびに使用方法
AU2004270161A1 (en) * 2003-08-28 2005-03-17 Nicox S.A. Nitrosated and nitrosylated cardiovascular compounds, compositions and methods of use
US20050096311A1 (en) * 2003-10-30 2005-05-05 Cns Response Compositions and methods for treatment of nervous system disorders
JP4965263B2 (ja) * 2003-12-12 2012-07-04 バイエル ファーマ アクチエンゲゼルシャフト 浸透増強剤を必要としないホルモンの経皮送達
US8668925B2 (en) * 2003-12-12 2014-03-11 Bayer Intellectual Property Gmbh Transdermal delivery of hormones without the need of penetration enhancers
CA2554716A1 (en) * 2004-01-22 2005-08-04 Nitromed, Inc. Nitrosated and/or nitrosylated compounds, compositions and methods of use
AU2005210637B2 (en) 2004-01-30 2010-09-16 A.V. Topchiev Institute Of Petrochemical Synthesis Rapidly dissolving film for delivery of an active agent
US20050191338A1 (en) * 2004-01-30 2005-09-01 Lifeng Kang Transdermal drug delivery composition comprising a small molecule gel and process for the preparation thereof
DE102004028284A1 (de) * 2004-06-11 2006-01-05 Hexal Ag Matrixkontrolliertes transdermales therapeutisches System auf Basis eines Schmelzklebstoffs zur Anwendung von Norelgestromin
KR20070048229A (ko) * 2004-08-05 2007-05-08 코리움 인터네셔널, 인크. 접착제 조성물
JP4824963B2 (ja) * 2004-08-12 2011-11-30 日東電工株式会社 貼付材及び貼付製剤
JP4745747B2 (ja) * 2004-08-12 2011-08-10 日東電工株式会社 フェンタニル含有貼付製剤
US20060121102A1 (en) * 2004-09-27 2006-06-08 Chia-Ming Chiang Transdermal systems for the delivery of estrogens and progestins
WO2006041855A2 (en) 2004-10-04 2006-04-20 Nitromed, Inc. Compositions and methods using apocynin compounds and nitric oxide donors
NZ582975A (en) 2004-10-21 2011-07-29 Durect Corp Transdermal delivery systems delivering sufentanil
US8252319B2 (en) 2004-10-21 2012-08-28 Durect Corporation Transdermal delivery system for sufentanil
JP2008528507A (ja) * 2005-01-21 2008-07-31 ニトロメッド インコーポレーティッド 複素環式の酸化窒素供与体基を含む心血管化合物、組成物および使用方法
CN1318032C (zh) * 2005-01-24 2007-05-30 浙江大学 炔雌醇透皮吸收贴片
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US20090042819A1 (en) * 2005-02-16 2009-02-12 Nitromed, Inc. Organic nitric oxide donor salts of antimicrobial compounds, compositions and methods of use
AU2006218766A1 (en) * 2005-02-28 2006-09-08 Nicox S.A. Cardiovascular compounds comprising nitric oxide enhancing groups, compositions and methods of use
JPWO2006093066A1 (ja) * 2005-02-28 2008-08-07 久光製薬株式会社 粘着基材及び該粘着基材を含む医療用貼付製剤
JP2008533031A (ja) * 2005-03-09 2008-08-21 ニトロメッド インコーポレーティッド アンギオテンシンｉｉアンタゴニストの有機酸化窒素増強塩、組成物および使用法
US20090131480A1 (en) 2005-04-04 2009-05-21 Eisai Co., Ltd. Dihydropyridine Compounds for Neurodegenerative Diseases and Dementia
US8962013B2 (en) 2005-05-02 2015-02-24 Bayer Intellectual Property Gmbh Multi-layered transdermal system with triazine UV absorber
US20060253963A1 (en) * 2005-05-10 2006-11-16 Limbaugh John M Body keep
US20090048219A1 (en) * 2005-05-23 2009-02-19 Nitromed Inc. Organic nitric oxide donor salts of nonsteroidal antiinflammatory compounds, compositions and methods of use
US7874489B2 (en) * 2005-06-20 2011-01-25 Authentiform Technologies, Llc Product authentication
US8458475B2 (en) * 2005-06-20 2013-06-04 Authentiform Technologies, L.L.C. Systems and methods for product authentication
US8247018B2 (en) * 2005-06-20 2012-08-21 Authentiform Technologies, Llc Methods for quality control
WO2007011763A2 (en) * 2005-07-15 2007-01-25 3M Innovative Properties Company Adhesive sheet and methods of use thereof
WO2007016677A2 (en) 2005-08-02 2007-02-08 Nitromed, Inc. Nitric oxide enhancing antimicrobial compounds, compositions and methods of use
US20070098772A1 (en) * 2005-09-23 2007-05-03 Westcott Tyler D Transdermal norelgestromin delivery system
EP1945030A4 (de) * 2005-10-04 2009-10-21 Nitromed Inc Genetische risikobeurteilung bei herzversagen: einfluss der genetischen variation auf den gly389arg-polymorphismus des beta 1 adrenergen rezeptors
AU2006299383A1 (en) * 2005-10-04 2007-04-12 Nitromed, Inc. Methods for treating respiratory disorders
AU2006299833B2 (en) 2005-10-12 2012-04-12 Besins Healthcare Luxembourg Sarl Improved testosterone gel and method of use
EP1954685A4 (de) * 2005-11-16 2009-11-11 Nitromed Inc Furoxanverbindungen, zusammensetzungen und anwendungsverfahren
EP1968584A2 (de) * 2005-12-20 2008-09-17 Nitromed, Inc. Stickoxid-verstärkende glutaminsäure-verbindungen, zusammensetzungen und anwendungsverfahren
WO2007075542A2 (en) * 2005-12-22 2007-07-05 Nitromed, Inc. Nitric oxide enhancing pyruvate compounds, compositions and methods of use
EP2010169A4 (de) * 2006-04-10 2010-09-08 Nitromed Inc Beurteilung des genetischen risikos bei herzversagen: auswirkung der genetischen variation des polymorphismus einer g-protein-beta-3-untereinheit
MX2008014870A (es) 2006-05-30 2009-02-12 Intarcia Therapeutics Inc Modulador de flujo para sistema de suministro osmotico con canal interno de dos piezas.
EP3421031A1 (de) 2006-08-09 2019-01-02 Intarcia Therapeutics, Inc Osmotisches verabreichungssystem mit kolbenanordnung
EP2056814B1 (de) 2006-08-16 2014-05-21 Amderma Pharmaceuticals, Llc 2,5-dihydroxybenzol-verbindungen zur behandlung von psoriasis
DE102006050558B4 (de) 2006-10-26 2009-03-26 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System enthaltend Norelgestromin zur Kontrazeption und Hormonsubstitution
ES2388355T3 (es) 2006-11-03 2012-10-11 Durect Corporation Sistemas de suministro transdémico que comprenden bupivacaína
WO2008067409A2 (en) * 2006-11-28 2008-06-05 Polyplus Battery Company Protected lithium electrodes for electro-transport drug delivery
BRPI0719307A2 (pt) * 2006-12-01 2014-02-04 Nitto Denko Corp Método para a supressão da descoloração ao longo do tempo da preparação adesiva contendo donepezil.
EP2098232B1 (de) * 2006-12-01 2013-06-05 Nitto Denko Corporation Zubereitung mit perkutaner absorption
US20100099714A1 (en) * 2007-03-05 2010-04-22 Eisai R&D Management Co., Ltd. AMPA and NMDA Receptor Antagonists for Neurodegenerative Diseases
CN101715340A (zh) 2007-04-23 2010-05-26 精达制药公司 促胰岛素释放肽的混悬制剂及其应用
JP2010524844A (ja) * 2007-04-26 2010-07-22 エーザイ・アール・アンド・ディー・マネジメント株式会社 認知症のためのシンナミド化合物
DE102007020799A1 (de) 2007-05-03 2008-11-06 Novosis Ag Transdermales therapeutisches System mit Remifentanil
US20090005824A1 (en) * 2007-06-29 2009-01-01 Polyplus Battery Company Electrotransport devices, methods and drug electrode assemblies
JP5192296B2 (ja) * 2007-07-05 2013-05-08 日東電工株式会社 貼付剤および貼付製剤
US20100178323A1 (en) 2007-07-10 2010-07-15 Agis Kydonieus Dermal Delivery Device
US20090069740A1 (en) * 2007-09-07 2009-03-12 Polyplus Battery Company Protected donor electrodes for electro-transport drug delivery
JP5209433B2 (ja) * 2007-10-19 2013-06-12 日東電工株式会社 貼付製剤
EP2240155B1 (de) 2008-02-13 2012-06-06 Intarcia Therapeutics, Inc Vorrichtungen, formulierungen und verfahren zur freisetzung mehrerer wirkstoffe
CA2725484A1 (en) * 2008-05-30 2009-12-03 Eisai R&D Management Co., Ltd. Percutaneously absorbable preparation
US20110056863A1 (en) * 2008-05-30 2011-03-10 Junichi Sekiya Adhesive preparation containing donepezil, and package of the same
WO2010042610A1 (en) 2008-10-08 2010-04-15 Agile Therapeutics, Inc. Transdermal delivery
WO2010042612A1 (en) 2008-10-08 2010-04-15 Agile Therapeutics, Inc. Transdermal delivery
ES2734510T3 (es) 2008-10-08 2019-12-10 Agile Therapeutics Inc Administración transdérmica
TWI541246B (zh) 2008-12-08 2016-07-11 歐陸斯迪公司 二氫羥戊甲嗎啡
CA2751884C (en) * 2009-01-14 2018-09-25 Corium International, Inc. Transdermal administration of tamsulosin
EP2410859A4 (de) 2009-03-27 2013-03-13 Agile Therapeutics Inc Transdermale freisetzung
SI2462246T1 (en) 2009-09-28 2018-01-31 Intarcia Therapeutics, Inc. Fast-setting and / or cessation of substantially unchanged delivery of the product
DE102010026879A1 (de) 2010-02-11 2011-08-11 AMW GmbH, 83627 Transdermales System mit Immunmodulator
DE102010026883A1 (de) 2010-03-11 2011-12-15 Amw Gmbh Transdermales System mit Aromatasehemmer
EP2377540A1 (de) 2010-03-31 2011-10-19 Hexal AG Transdermales Pflaster mit 17-Deacetyl-Norgestimat
RU2445084C2 (ru) * 2010-04-27 2012-03-20 Государственное образовательное учреждение высшего профессионального образования Смоленская государственная медицинская академия федерального агентства по здравоохранению и социальному развитию Трансдермальный пластырь
DE102011100619A1 (de) 2010-05-05 2012-01-05 Amw Gmbh Transdermales therapeutisches System (TTS) mit einem Gehalt an einem Opiod-Analgetikum
DE102010026903A1 (de) 2010-07-12 2012-01-12 Amw Gmbh Transdermales therapeutisches System mit Avocadoöl oder Palmöl als Hilfsstoff
WO2012095548A2 (es) 2011-01-13 2012-07-19 Centro De Investigación Biomédica En Red De Enfermedades Neurodegenerativas (Ciberned) Compuestos para el tratamiento de enfermedades neurodegenerativas
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
FR2992325B1 (fr) 2012-06-26 2015-05-22 Ab7 Innovation Matrice sequencee multifonctionnelle monopolymerique en polyurethane coule et procede de fabrication
EP2915098A4 (de) 2012-10-30 2016-07-06 Certirx Corp Produkt-, bild- oder dokumentenauthentifizierung und -verifizierung und objektidentifikation
GB201309654D0 (en) 2013-05-30 2013-07-17 Euro Celtique Sa Method
EP2821071A1 (de) 2013-07-04 2015-01-07 Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) Verbindungen zur Brustkrebsbehandlung
WO2015007326A1 (en) 2013-07-18 2015-01-22 Institut D'investigació Biomèdica De Bellvitge (Idibell) Agents comprising a terminal alpha-galactosyl moiety for use in prevention and/or treatment of inflammatory diseases
KR101881791B1 (ko) * 2013-10-07 2018-07-25 테이코쿠 팔마 유에스에이, 인코포레이티드 비진정성 덱스메데토미딘 경피 조성물을 사용하여 금단 증후군을 치료하기 위한 방법 및 조성물
TWI629066B (zh) 2013-10-07 2018-07-11 帝國製藥美國股份有限公司 使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物
KR101948779B1 (ko) * 2013-10-07 2019-05-21 테이코쿠 팔마 유에스에이, 인코포레이티드 덱스메데토미딘 경피 전달 장치 및 이의 사용 방법
EP3054931B1 (de) * 2013-10-07 2020-12-23 Teikoku Pharma USA, Inc. Transdermale abgabevorrichtung zur behandlung von schmerzen mit transdermalen dexmedetomidinzusammensetzungen
JP6188933B2 (ja) 2013-10-07 2017-08-30 テイコク ファーマ ユーエスエー インコーポレーテッド 非鎮静量のデクスメデトミジンの経皮送達用方法及び組成物
EP2930238A1 (de) 2014-04-09 2015-10-14 Fundacio Centre de Regulacio Genomica Zusammensetzungen zur Behandlung von Krebs
EP2949324A1 (de) 2014-05-27 2015-12-02 Consorci Institut Catala de Ciencies Cardiovasculars Prävention und/oder Behandlung von Ischämie-/Reperfusionsschäden
EP2957634A1 (de) 2014-06-20 2015-12-23 Consejo Superior De Investigaciones Científicas Verbindungen zur Prävention und/oder Behandlung von fibrotischen Erkrankungen
EP2977463A1 (de) 2014-07-25 2016-01-27 Centro de Investigación Biomédica en Red (CIBER) Verfahren und Wirkstoffe im Zusammenhang mit Lungenerkrankungen
EP2987503A1 (de) 2014-08-22 2016-02-24 Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) Verfahren und Reagenzien zur Prävention und/oder Behandlung von Infektionen
EP2997977A1 (de) 2014-09-19 2016-03-23 Fundación de la Comunidad Valenciana Centro de Investigación Principe Felipe Spezifische MTOR-Inhibitoren zur Behandlung von X-verbundener Adrenoleukodystrophie
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
EP3067369A1 (de) 2015-03-11 2016-09-14 Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) Verfahren und zusammensetzungen zur behandlung von antiangiogenresistentem krebs
EP3085366A1 (de) 2015-04-22 2016-10-26 Institut du Cerveau et de la Moelle Epiniere-ICM Nmda-antagonisten zur behandlung von mentalen erkrankungen mit auftreten von aggressivem und/oder impulsivem verhalten
US20180125860A1 (en) 2015-05-18 2018-05-10 Agile Therapeutics, Inc. Contraceptive Compositions and Methods for Improved Efficacy and Modulation of Side Effects
KR102650751B1 (ko) 2015-06-03 2024-03-22 인타르시아 세라퓨틱스 인코포레이티드 임플란트 배치 및 제거 시스템들
EP3356384B1 (de) 2015-09-29 2023-11-29 Paris Sciences et Lettres Polypeptide mit vinculinbindungsstellen zur behandlung der proliferation und/oder adhäsion verwandter erkrankungen
CN105416940A (zh) * 2015-11-30 2016-03-23 芜湖成德龙过滤设备有限公司 便于清洁的货架
EP3219326A1 (de) 2016-03-14 2017-09-20 Institut Catalá De Ciencies Cardiovasculars (ICCC) Prävention und/oder behandlung von ischämie-/reperfusionsverletzungen
SG10201913699QA (en) 2016-05-16 2020-03-30 Intarcia Therapeutics Inc Glucagon-receptor selective polypeptides and methods of use thereof
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
EP3556359A4 (de) 2016-12-19 2020-08-05 Nutritape, S.L. Energetisierungspflaster für sportler
AU2018206539A1 (en) 2017-01-03 2019-07-18 Intarcia Therapeutics, Inc. Methods comprising continuous administration of a GLP-1 receptor agonist and co-administration of a drug
WO2018162581A1 (en) 2017-03-07 2018-09-13 OP2 Drugs Desmethylanethole trithione derivatives for the treatment of diseases linked to mitochondrial reactive oxygen species (ros) production
EP3385276A1 (de) 2017-04-03 2018-10-10 Targedys Aus clpb abgeleitete proteine und verwendungen davon
ES2932076T3 (es) 2017-10-27 2023-01-11 Association Pour La Rech A Ligbmc Ari Moduladores agonistas de los receptores de glucocorticoides selectivos (SEGRAM) no esteroideos y usos de los mismos
EP3569228A1 (de) 2018-05-17 2019-11-20 Association pour la recherche à l'IGBMC (ARI) Nichtsteroidale selektive glucocorticoid-rezeptor-agonistische modulatoren (segramme) und verwendungen davon
EP3539975A1 (de) 2018-03-15 2019-09-18 Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron Mikropeptide und verwendungen davon
US20220071330A1 (en) * 2018-08-07 2022-03-10 Erin Marie Tedesco Hair Extension Device and Method
IL281161B2 (en) 2018-09-06 2024-01-01 OP2 Drugs A pharmaceutical preparation comprising cyclodextrin complexes of antholetrition or its derivatives

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE655916C (de) * 1934-03-04 1938-01-25 Mitteldeutsche Stahlwerke Akt Spurlager fuer Schleusentore
ATE95430T1 (de) * 1984-12-22 1993-10-15 Sanol Arznei Schwarz Gmbh Wirkstoffpflaster.
CA1272445A (en) * 1985-02-25 1990-08-07 Yie W. Chien Transdermal pharmaceutical absorption dosage unit and process of pharmaceutical administration
US4818540A (en) * 1985-02-25 1989-04-04 Rutgers, The State University Of New Jersey Transdermal fertility control system and process
US5296230A (en) * 1985-02-25 1994-03-22 Rutgers, The State University Of New Jersey Transdermal fertility control system and process
US4883669A (en) * 1985-02-25 1989-11-28 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit for estradiol and other estrogenic steroids and process for administration
CA1288698C (en) * 1985-08-30 1991-09-10 Yie W. Chien Transdermal anti-anginal pharmaceutical dosage
US5145682A (en) * 1986-05-30 1992-09-08 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit for postmenopausal syndrome treatment and process for administration
US5560922A (en) * 1986-05-30 1996-10-01 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit using a polyacrylate adhesive polymer and process
US4906169A (en) * 1986-12-29 1990-03-06 Rutgers, The State University Of New Jersey Transdermal estrogen/progestin dosage unit, system and process
US5023084A (en) * 1986-12-29 1991-06-11 Rutgers, The State University Of New Jersey Transdermal estrogen/progestin dosage unit, system and process
JPH0720866B2 (ja) * 1987-05-15 1995-03-08 三生製薬株式会社 エペリゾン又はトルペリゾン或いはそれらの塩類含有経皮適用製剤
US5422119A (en) * 1987-09-24 1995-06-06 Jencap Research Ltd. Transdermal hormone replacement therapy
US4898920A (en) * 1987-10-15 1990-02-06 Dow Corning Corporation Adhesive compositions, controlled release compositions and transdermal delivery device
US5656286A (en) † 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US4994267A (en) * 1988-03-04 1991-02-19 Noven Pharmaceuticals, Inc. Transdermal acrylic multipolymer drug delivery system
US5474783A (en) * 1988-03-04 1995-12-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5788983A (en) * 1989-04-03 1998-08-04 Rutgers, The State University Of New Jersey Transdermal controlled delivery of pharmaceuticals at variable dosage rates and processes
US5232707A (en) * 1989-07-10 1993-08-03 Syntex (U.S.A.) Inc. Solvent extraction process
US5252334A (en) † 1989-09-08 1993-10-12 Cygnus Therapeutic Systems Solid matrix system for transdermal drug delivery
DE3933460A1 (de) * 1989-10-06 1991-04-18 Lohmann Therapie Syst Lts Oestrogenhaltiges wirkstoffpflaster
US5508038A (en) * 1990-04-16 1996-04-16 Alza Corporation Polyisobutylene adhesives for transdermal devices
MY115126A (en) * 1990-04-27 2003-04-30 Seikisui Chemical Co Ltd Percutaneously absorbable eperisone or tolperisone preparation.
EP0555360A1 (de) * 1990-10-29 1993-08-18 Alza Corporation Transdermale verhütungsmittelformulierung, verfahren und vorrichtung
US5314694A (en) * 1990-10-29 1994-05-24 Alza Corporation Transdermal formulations, methods and devices
US5232702A (en) * 1991-07-22 1993-08-03 Dow Corning Corporation Silicone pressure sensitive adhesive compositons for transdermal drug delivery devices and related medical devices
DE4210711A1 (de) † 1991-10-31 1993-05-06 Schering Ag Berlin Und Bergkamen, 1000 Berlin, De Transdermale therapeutische systeme mit kristallisationsinhibitoren
JP2960832B2 (ja) * 1992-05-08 1999-10-12 ペルマテック テクノロジー アクチェンゲゼルシャフト エストラジオールの投与システム
DE4227989A1 (de) * 1992-08-21 1994-06-09 Schering Ag Mittel zur transdermalen Applikation enthaltend 3-Keto-desogestrel
AU7396294A (en) * 1993-06-25 1995-01-24 Alza Corporation Incorporating poly-n-vinyl amide in a transdermal system
DE4333595A1 (de) * 1993-10-01 1995-04-06 Labtec Gmbh Transdermales therapeutisches System zur Applikation von Arzneimitteln auf die Haut
US5741511A (en) * 1995-04-12 1998-04-21 Sam Yang Co., Ltd. Transdermal drug delivery device for treating erectile dysfunction
WO1996040087A2 (en) * 1995-06-07 1996-12-19 Cygnus, Inc. Pressure sensitive acrylate adhesive composition cross-linked with aluminum acetylacetonate and containing a drug having a reactive aromatic hydroxyl group
US5762956A (en) * 1996-04-24 1998-06-09 Rutgers, The State University Of New Jersey Transdermal contraceptive delivery system and process
US5783208A (en) * 1996-07-19 1998-07-21 Theratech, Inc. Transdermal drug delivery matrix for coadministering estradiol and another steroid

Also Published As

Publication number Publication date
JPH11501323A (ja) 1999-02-02
EP0836506B1 (de) 2002-12-18
CA2222133A1 (en) 1996-12-19
PL181582B1 (pl) 2001-08-31
NO975586D0 (no) 1997-12-03
DE69625483T3 (de) 2012-05-10
PL323729A1 (en) 1998-04-14
US5972377A (en) 1999-10-26
PT836506E (pt) 2003-04-30
CA2222133C (en) 2002-12-24
ES2190472T5 (es) 2012-03-09
IL122432A0 (en) 1998-06-15
EP0836506A1 (de) 1998-04-22
AU703593B2 (en) 1999-03-25
KR19990022722A (ko) 1999-03-25
CN1188189C (zh) 2005-02-09
CZ292151B6 (cs) 2003-08-13
HU228434B1 (en) 2013-03-28
IL122432A (en) 2000-07-16
DE69625483D1 (de) 2003-01-30
CZ393297A3 (cs) 1999-06-16
EP0836506B2 (de) 2011-12-21
US6071531A (en) 2000-06-06
NZ311304A (en) 1999-03-29
EP0836506A4 (de) 1999-05-26
AU6259796A (en) 1996-12-30
US5876746A (en) 1999-03-02
DK0836506T3 (da) 2003-04-07
ATE229828T1 (de) 2003-01-15
KR100301226B1 (ko) 2002-07-06
HUP9802326A2 (hu) 1999-02-01
JP2004043510A (ja) 2004-02-12
DK0836506T4 (da) 2012-01-30
ES2190472T3 (es) 2003-08-01
CN1190351A (zh) 1998-08-12
MX9709666A (es) 1998-10-31
NO975586L (no) 1998-01-27
RU2177311C2 (ru) 2001-12-27
UA48973C2 (uk) 2002-09-16
HUP9802326A3 (en) 1999-07-28
NO316308B1 (no) 2004-01-12
JP3534775B2 (ja) 2004-06-07
WO1996040355A1 (en) 1996-12-19

Similar Documents

Publication Publication Date Title
DE69625483T2 (de) Transdermales pflaster zur verabreichung von 17-deacetyl norgestimat alleine oder in kombination mit einem östrogen
DE3855606T2 (de) Verwendung von Melatonin zur Herstellung einer kontrazeptiven Zusammensetzung
NZ516502A (en) Administration of non-oral androgenic steroids to women having an elevated level of sex hormone binding globulin (SHBG)
KR960700727A (ko) 호르몬 대체 치료(hormone replacement therapy)
BR9709934A (pt) Kit de terapia de reposição hormonal e/ou contraceptivo uso de unidades de dosagem diária consistindo essecialmente de um progestogênio e processo de preparação de um sistema de liberação de droga
NO954611L (no) Metoder og preparater for anvendelse i behandling av benigne gynekologiske sykdommer
NZ536633A (en) Percutaneous delivery of testosterone via a hydroalcoholic gel as a method of increasing testosterone and related steroid concentrations in women
HUP9904344A2 (hu) Egyfázisú fogamzásgátló eljárás és progesztin és ösztrogén kombinációját tartalmazó kit
RU2005128284A (ru) Продленные режимы чрескожной контрацепции
MXPA05003364A (es) Parche transdermico de 17(-estradiol/levonorgestrel para hormonoterapia restitutiva.

Legal Events

Date Code Title Description
8363 Opposition against the patent
8328 Change in the person/name/address of the agent

Representative=s name: BOEHMERT & BOEHMERT, 28209 BREMEN

R102 Epo decision maintaining patent in amended form now final

Ref document number: 836506

Country of ref document: EP

R102 Epo decision maintaining patent in amended form now final

Ref document number: 836506

Country of ref document: EP

Effective date: 20111221