DE69631476D1 - Vorrichtung zur dosierten inhalierung von beclomethason-diproprionat - Google Patents

Vorrichtung zur dosierten inhalierung von beclomethason-diproprionat

Info

Publication number
DE69631476D1
DE69631476D1 DE69631476T DE69631476T DE69631476D1 DE 69631476 D1 DE69631476 D1 DE 69631476D1 DE 69631476 T DE69631476 T DE 69631476T DE 69631476 T DE69631476 T DE 69631476T DE 69631476 D1 DE69631476 D1 DE 69631476D1
Authority
DE
Germany
Prior art keywords
dosed
inhalation
beclomethasone diproprionate
diproprionate
beclomethasone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE69631476T
Other languages
English (en)
Other versions
DE69631476T2 (de
Inventor
C Ashurst
S Herman
Li Li-Bovet
T Riebe
Ignatius Loy Britto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23674168&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69631476(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of DE69631476D1 publication Critical patent/DE69631476D1/de
Application granted granted Critical
Publication of DE69631476T2 publication Critical patent/DE69631476T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/44—Valves specially adapted therefor; Regulating devices
    • B65D83/52—Valves specially adapted therefor; Regulating devices for metering
    • B65D83/54—Metering valves ; Metering valve assemblies
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/75—Aerosol containers not provided for in groups B65D83/16 - B65D83/74
    • B65D83/752—Aerosol containers not provided for in groups B65D83/16 - B65D83/74 characterised by the use of specific products or propellants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0222—Materials for reducing friction
DE1996631476 1995-04-14 1996-04-11 Vorrichtung zur dosierten inhalierung von beclomethason-diproprionat Revoked DE69631476T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42228095A 1995-04-14 1995-04-14
US422280 1995-04-14
PCT/US1996/005009 WO1996032345A1 (en) 1995-04-14 1996-04-11 Metered dose inhaler for beclomethasone dipropionate

Publications (2)

Publication Number Publication Date
DE69631476D1 true DE69631476D1 (de) 2004-03-11
DE69631476T2 DE69631476T2 (de) 2005-01-13

Family

ID=23674168

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1996631476 Revoked DE69631476T2 (de) 1995-04-14 1996-04-11 Vorrichtung zur dosierten inhalierung von beclomethason-diproprionat

Country Status (26)

Country Link
US (3) US6149892A (de)
EP (1) EP0820414B1 (de)
JP (1) JP3573213B2 (de)
KR (1) KR19980703850A (de)
CN (1) CN1186473A (de)
AP (1) AP835A (de)
AT (1) ATE258813T1 (de)
AU (1) AU718851B2 (de)
BG (1) BG102023A (de)
BR (1) BR9604979A (de)
CA (1) CA2218179A1 (de)
CZ (1) CZ326197A3 (de)
DE (1) DE69631476T2 (de)
EA (1) EA000889B1 (de)
EE (1) EE9700372A (de)
ES (1) ES2214536T3 (de)
GE (1) GEP20002266B (de)
HU (1) HUP9800641A3 (de)
IS (1) IS4581A (de)
NO (1) NO974738L (de)
NZ (1) NZ306281A (de)
OA (1) OA10625A (de)
PL (1) PL180880B1 (de)
SK (1) SK139197A3 (de)
TR (1) TR199701170T1 (de)
WO (1) WO1996032345A1 (de)

Families Citing this family (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4003270A1 (de) * 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgase und ihre verwendung in arzneimittelzubereitungen
CA2218179A1 (en) * 1995-04-14 1996-10-17 Glaxo Wellcome Inc. Metered dose inhaler for beclomethasone dipropionate
SK284448B6 (sk) * 1995-04-14 2005-04-01 Glaxo Wellcome Inc. Merací dávkovací inhalátor
SK284447B6 (sk) * 1995-04-14 2005-04-01 Glaxo Wellcome Inc. Merací dávkovací inhalátor
GB9526392D0 (en) 1995-12-22 1996-02-21 Glaxo Group Ltd Medicaments
GB9616237D0 (en) 1996-08-01 1996-09-11 Norton Healthcare Ltd Aerosol formulations
WO1998024420A1 (en) * 1996-12-04 1998-06-11 Bioglan Ireland (R & D) Limited Pharmaceutical compositions and devices for their administration
US6413496B1 (en) 1996-12-04 2002-07-02 Biogland Ireland (R&D) Limited Pharmaceutical compositions and devices for their administration
ID22975A (id) * 1997-03-18 1999-12-23 Basf Ag Metode dan komposisi untuk memodulasi respons terhadap kortikosteroid
US6054487A (en) * 1997-03-18 2000-04-25 Basf Aktiengesellschaft Methods and compositions for modulating responsiveness to corticosteroids
US6120752A (en) * 1997-05-21 2000-09-19 3M Innovative Properties Company Medicinal aerosol products containing formulations of ciclesonide and related steroids
US20010031244A1 (en) 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
GB2338951B (en) * 1997-09-03 2000-06-21 Bespak Plc Improvements in or relating to metering valves for pressuriseddispensing containers
US20030103906A1 (en) * 1997-10-14 2003-06-05 Smithkline Beecham Corporation Metered dose inhaler having internal surfaces coated with fluorocarbon polymer
GB9814717D0 (en) * 1998-02-23 1998-09-02 Bespak Plc Improvements in drug delivery devices
AU753921B2 (en) * 1998-02-23 2002-10-31 Glaxo Group Limited Improvements in drug delivery devices
MXPA00008174A (es) * 1998-02-23 2004-03-10 Glaxo Group Ltd Mejoras en los dispositivos de distribucion de medicamento.
GB9805938D0 (en) * 1998-03-19 1998-05-13 Glaxo Group Ltd Valve for aerosol container
CA2329900A1 (en) * 1998-04-30 1999-11-04 3M Innovative Properties Company Metered-dose valve for pharmaceutical aerosol
GB2340759B (en) * 1998-08-26 2003-05-07 Bespak Plc Improvements in drug delivery devices
DZ2947A1 (fr) 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
US6315112B1 (en) 1998-12-18 2001-11-13 Smithkline Beecham Corporation Method and package for storing a pressurized container containing a drug
US6352152B1 (en) 1998-12-18 2002-03-05 Smithkline Beecham Corporation Method and package for storing a pressurized container containing a drug
US6390291B1 (en) 1998-12-18 2002-05-21 Smithkline Beecham Corporation Method and package for storing a pressurized container containing a drug
US7168597B1 (en) 1999-03-12 2007-01-30 Smithkline Beecham Corporation Aerosol metering valve
US6315985B1 (en) * 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
IT1313553B1 (it) 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
IT1317720B1 (it) * 2000-01-07 2003-07-15 Chiesi Farma Spa Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani.
DE10004465A1 (de) 2000-02-02 2001-08-16 Pari Gmbh Inhalationsvernebler
IT1317846B1 (it) * 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
AU2001234005B2 (en) 2000-02-28 2006-01-19 Pharmakodex Limited Improvements in or relating to the delivery of oral drugs
EP1259276A2 (de) * 2000-03-01 2002-11-27 Glaxo Group Limited Dosierinhalator
WO2001064274A2 (en) * 2000-03-01 2001-09-07 Glaxo Group Limited Metered dose inhaler
US20030183224A1 (en) * 2000-03-01 2003-10-02 Hailey Mark Andrew Metered dose inhaler
US20030183223A1 (en) * 2000-03-01 2003-10-02 Hailey Andrew Mark Metered dose inhaler
IT1318514B1 (it) * 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
JP5392880B2 (ja) * 2000-05-22 2014-01-22 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ 加圧式定量吸入器のための安定な製薬学的溶液製剤
US20030180228A1 (en) * 2000-05-23 2003-09-25 Cripps Alan Leslie Aerosol container for formulations of salmeterol xinafoate
AU2001270074A1 (en) 2000-06-22 2002-01-02 Glaxo Group Limited Method and package for storing a pressurized container containing a drug
GB0016876D0 (en) * 2000-07-11 2000-08-30 Astrazeneca Ab Novel formulation
EP1309503B1 (de) * 2000-08-18 2004-10-20 Norton Healthcare Limited Ärztliche sprühvorrichtung
WO2002024552A2 (en) 2000-09-18 2002-03-28 Glaxo Group Limited Coated can for a metered dose inhaler
GB2367756B (en) 2000-10-12 2003-01-08 Bespak Plc Dispensing apparatus
SE0004610D0 (sv) 2000-12-13 2000-12-13 Astrazeneca Ab Surface modification process
MXPA03005697A (es) * 2000-12-22 2003-10-06 Glaxo Group Ltd Inhalador de dosis medida para xinafoato de salmeterol.
GB2375098B (en) 2001-04-30 2003-08-27 Bespak Plc Improvements in valves for pressurised dispensing containers
US20030051728A1 (en) 2001-06-05 2003-03-20 Lloyd Peter M. Method and device for delivering a physiologically active compound
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
US7645442B2 (en) 2001-05-24 2010-01-12 Alexza Pharmaceuticals, Inc. Rapid-heating drug delivery article and method of use
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
SI1273292T1 (en) 2001-07-02 2004-12-31 Chiesi Farmaceutici S.P.A. Optimised formulation of tobramycin for aerosolization
GB0122725D0 (en) * 2001-09-21 2001-11-14 Glaxo Group Ltd Drug dispensing components
GB2384190A (en) 2002-01-22 2003-07-23 Bespak Plc Dispensing device for a powdered product
SE0200313D0 (sv) * 2002-02-01 2002-02-01 Astrazeneca Ab Novel process
US20040126325A1 (en) * 2002-03-12 2004-07-01 David Lewis Medicinal aerosol solution formulation products with improved chemical stability
AU2003270602A1 (en) * 2002-09-13 2004-04-30 Glaxo Group Limited Coated blending system
US20040105818A1 (en) 2002-11-26 2004-06-03 Alexza Molecular Delivery Corporation Diuretic aerosols and methods of making and using them
US7913688B2 (en) 2002-11-27 2011-03-29 Alexza Pharmaceuticals, Inc. Inhalation device for producing a drug aerosol
AU2003293361A1 (en) * 2002-12-18 2004-07-29 Glaxo Group Limited Drug delivery system with vented mouthpiece
EA009087B1 (ru) * 2003-03-20 2007-10-26 Бёрингер Ингельхайм Фармасьютиклз, Инк. Состав для ингалятора, выдающего мерную дозу препарата, с использованием гидрофторалканов в качестве пропеллентов
US20040191176A1 (en) * 2003-03-28 2004-09-30 Kaplan Leonard W Formulations for treatment of pulmonary disorders
US20060225733A1 (en) * 2003-06-24 2006-10-12 Cipla Limited Pharmaceutical dispensing aid
MXPA06001642A (es) 2003-08-11 2006-04-28 Glaxo Group Ltd Inhalador farmaceutico de dosis medida y metodos relacionados con el mismo.
US20080190418A1 (en) 2003-08-29 2008-08-14 Glaxo Group Limited Pharmaceutical Metered Dose Inhaler and Methods Relating Thereto
EP1686960A4 (de) * 2003-10-28 2007-03-07 Glaxo Group Ltd Inhalbierbare pharmazeutische formulierungen mit lactoseanhydrat und verabreichungsverfahren dafür
EP1595531A1 (de) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stabile Arzneimittellösung für Druckdosierinhalatoren
FR2872494B1 (fr) * 2004-07-01 2006-11-17 Valois Sas Distributeur de produits fluide ou pulverisant
CA2571519C (en) * 2004-07-02 2013-05-14 Boehringer Ingelheim International Gmbh Aerosol suspension formulations containing tg 227 ea or tg 134 a as a propellant
JP5156397B2 (ja) 2005-02-10 2013-03-06 グラクソ グループ リミテッド 予備分級技術を用いて乳糖を製造する方法及びその乳糖から形成させた医薬製剤
US20090029901A1 (en) * 2005-02-10 2009-01-29 Marian Wood-Kaczmar Process for Crystallizing Lactose Particles for Use in Pharmaceutical Formulations
DE102006017320A1 (de) * 2006-04-11 2007-10-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel
CN104188907A (zh) 2007-02-11 2014-12-10 Map药物公司 治疗性施用dhe用于快速减轻偏头痛而使副作用分布最小化的方法
WO2008112661A2 (en) 2007-03-09 2008-09-18 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
GB0721739D0 (en) 2007-11-06 2007-12-19 3M Innovative Properties Co medicinal inhalation devices and components thereof
GB0721737D0 (en) 2007-11-06 2007-12-19 3M Innovative Properties Co Medicinal inhalation devices and components thereof
US8430097B2 (en) 2007-11-06 2013-04-30 3M Innovative Properties Company Medicinal inhalation devices and components thereof
US8227027B2 (en) 2007-12-07 2012-07-24 Presspart Gmbh & Co. Kg Method for applying a polymer coating to an internal surface of a container
EA022312B1 (ru) * 2008-09-04 2015-12-30 Мария Клементине Мартин Клостерфрау Фертрибсгезелльшафт Мбх Монотерпены для лечения заболеваний дыхательных путей, в частности бронхолегочных заболеваний
GB2456028A (en) * 2008-11-14 2009-07-01 Consort Medical Plc A medicament dispenser with an HFO propellant
CA2760808A1 (en) 2009-05-06 2010-11-11 3M Innovative Properties Company Medicinal inhalation devices and components thereof
CN102803555A (zh) 2009-05-06 2012-11-28 3M创新有限公司 药物吸入装置
WO2010129783A1 (en) 2009-05-06 2010-11-11 3M Innovative Properties Company Apparatus and method for plasma treatment of containers
MX2012005711A (es) 2009-11-17 2012-10-05 Cipla Ltd Soluciones de inhalacion.
US10231948B2 (en) 2017-02-27 2019-03-19 Jason Ty Nguyen Metered dose inhaler compositions, systems, and methods
US11779716B2 (en) * 2017-08-03 2023-10-10 Kindeva Drug Delivery L.P. Method for making medicinal delivery device having multi-layer coating
GB201717996D0 (en) 2017-10-31 2017-12-13 Portal Medical Ltd Medicament dispenser device
CN110840864B (zh) * 2019-12-20 2022-02-22 广州健康元呼吸药物工程技术有限公司 一种β2受体激动剂吸入气雾剂及包含该吸入气雾剂的产品
WO2021165348A1 (en) * 2020-02-20 2021-08-26 Chiesi Farmaceutici S.P.A. Pressurised metered dose inhalers comprising a buffered pharmaceutical formulation

Family Cites Families (111)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT12188B (de) 1901-04-18 1903-06-10 William Chapman
US2562118A (en) * 1950-02-09 1951-07-24 Du Pont Polytetrafluoroethylene coating compositions
NL208432A (de) * 1954-09-20
US2968427A (en) * 1955-06-28 1961-01-17 Meshberg Philip Valve for aerosol container
GB878409A (en) * 1957-03-26 1961-09-27 United Drug And Chemical Compa Improvements in or relating to dispensing devices
US2886217A (en) * 1957-05-20 1959-05-12 Riker Laboratories Inc Dispensing device
US2892576A (en) * 1957-11-14 1959-06-30 Lawrence T Ward Metering button valve assembly
US2980301A (en) * 1958-09-02 1961-04-18 Riker Laboratories Inc Metering valve for aerosol container
GB864392A (en) * 1958-11-10 1961-04-06 Rexall Drug Company Ltd Improvements in or relating to dispensing devices for aerosols
US3506737A (en) 1965-10-23 1970-04-14 Owens Illinois Inc Glass aerosol bottles and method for making same
GB1191700A (en) 1967-02-27 1970-05-13 Ekco Prod Inc Coated Metalware
US3505737A (en) * 1967-10-02 1970-04-14 Theodore L Merolla Fluid substitution device
FR1584784A (de) * 1968-08-13 1970-01-02
FR2082593A5 (en) 1970-03-20 1971-12-10 Oreal Aerosol can prodn
NO134730L (de) 1971-07-19 1900-01-01
LU63737A1 (de) 1971-08-17 1972-01-04
US4087026A (en) * 1971-09-15 1978-05-02 Petterson Tor H Barrier package
US3896602A (en) * 1971-09-15 1975-07-29 Tor H Petterson Method of manufacturing of a barrier package
FR2159593A5 (fr) * 1971-11-04 1973-06-22 Skm Sa Installation de peinture par pulverisation
US4143204A (en) * 1971-12-27 1979-03-06 E. I. Du Pont De Nemours And Company Articles coated with fluorocarbon resins
DE2227142A1 (de) * 1972-06-03 1973-12-13 Pampus Kg Rohre und behaelter aus glasfaserverstaerktem kunststoff und einer auskleidung, zum beispiel aus ptfe
US3962171A (en) * 1973-03-02 1976-06-08 Mcgarry & Waters Composition for protecting surfaces
US3929537A (en) * 1973-07-19 1975-12-30 Austral Erwin Engineering Co Preparation of plastic-metal laminates
FR2267496A1 (en) * 1974-04-11 1975-11-07 Sidel Sa Method of sealing valve on aerosol container - uses internally ribbed sleeve over ribbed valve and sleeve
US4180609A (en) * 1975-07-11 1979-12-25 E. I. Du Pont De Nemours And Company Article coated with fluoropolymer finish with improved scratch resistance
JPS5327120A (en) 1976-08-26 1978-03-14 Union Carbide Corp Plasticssmade aerosol containers and method of producing the same
GB2003415A (en) 1977-09-02 1979-03-14 American Can Co Improvements relating to the manufacture of containers
US4125152A (en) * 1977-09-19 1978-11-14 Borg-Warner Corporation Scale resistant heat transfer surfaces and a method for their preparation
JPS5920547B2 (ja) * 1979-07-04 1984-05-14 東洋製罐株式会社 溶接缶
DE2947025A1 (de) * 1979-11-22 1981-06-04 Glyco-Metall-Werke Daelen & Loos Gmbh, 6200 Wiesbaden Zwei- oder mehrschicht-verbundwerkstoff
ZA807387B (en) * 1979-12-08 1981-11-25 Metal Box Co Ltd Containers
PH24267A (en) * 1980-02-15 1990-05-29 Glaxo Group Ltd Androstane carbothioates and pharmaceutical compositions containing the same
GB2077229B (en) * 1980-05-16 1983-08-03 Neotechnic Eng Ltd Valve assembly for a pressurized aerosoldispensing container
GB2105189B (en) 1981-07-24 1985-03-20 Fisons Plc Inhalation drugs
ZW6584A1 (en) * 1983-04-18 1985-04-17 Glaxo Group Ltd Phenethanolamine derivatives
US4487878A (en) * 1983-06-30 1984-12-11 E. I. Du Pont De Nemours And Company Coating composition of a solution fluorocarbon polymer, a dispersed fluorocarbon polymer and a polyamine curing agent
EP0199487B1 (de) * 1985-04-19 1991-03-06 Nippon Steel Corporation Büchse und Verfahren zur Herstellung von Büchsen
NL8501767A (nl) * 1985-06-19 1987-01-16 Euro Technical Oilservices Bv Inrichting voor het behandelen van een verontreinigingen bevattende vloeistof.
DE3778727D1 (de) * 1986-02-27 1992-06-11 Nippon Kokan Kk Grundbeschichtete metallplatte.
JPS6312445A (ja) * 1986-06-24 1988-01-19 東洋製罐株式会社 イ−ジイオ−プン蓋付缶体及びその製法
US4897439A (en) * 1986-07-01 1990-01-30 Edlon Products, Inc. Polymer-metal bonded composite and method of producing same
US5536583A (en) * 1986-07-01 1996-07-16 Edlon Products, Inc. Polymer metal bonded composite and method of producing same
EP0260084B1 (de) * 1986-09-08 1992-12-30 Asia Can Company Limited Metallbehälter und Verfahren zu seiner Herstellung
US4819834A (en) * 1986-09-09 1989-04-11 Minnesota Mining And Manufacturing Company Apparatus and methods for delivering a predetermined amount of a pressurized fluid
GB2205297B (en) * 1987-06-05 1991-06-19 Lin Pac Mouldings A container assembly
AU606182B2 (en) * 1987-06-26 1991-01-31 Winfried Jean Werding Device for storing and controlled dispensing of pressurized products
DE8709978U1 (de) * 1987-07-21 1987-10-08 A. U. K. Mueller Gmbh & Co Kg, 4000 Duesseldorf, De
GB8724243D0 (en) * 1987-10-15 1987-11-18 Metal Box Plc Laminates of polyolefin-based film
GB8724242D0 (en) * 1987-10-15 1987-11-18 Metal Box Plc Laminated metal sheet
IT1223451B (it) * 1987-11-24 1990-09-19 Coster Tecnologie Speciali Spa Procedimento per ottenere fondelli metallici protetti per valvole per aerosol e simili
GB2214891A (en) 1988-02-05 1989-09-13 Fibrenyle Ltd Containers for pressurized material
DE68915203T2 (de) * 1988-03-22 1994-09-22 Fisons Plc Pharmazeutische Mischungen.
IL89713A0 (en) * 1988-03-29 1989-09-28 Ciba Geigy Ag Novel alkanophenones
JPH0289633A (ja) 1988-05-20 1990-03-29 Sumitomo Electric Ind Ltd フッ素樹脂被覆物
US4961966A (en) * 1988-05-25 1990-10-09 The United States Of America As Represented By The Administrator Of The Environmental Protection Agency Fluorocarbon coating method
US4902318A (en) * 1988-05-25 1990-02-20 The United States Of America As Represented By The Administrator Of The Environmental Protection Agency Inlet apparatus for gas-aerosol sampling
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
GB8903629D0 (en) * 1989-02-17 1989-04-05 Metal Box Plc Metal/polymer laminates
US5176132A (en) * 1989-05-31 1993-01-05 Fisons Plc Medicament inhalation device and formulation
US5006383A (en) * 1989-06-28 1991-04-09 The Dow Chemical Company Polymeric blend and laminated structures prepared therefrom
FR2650219B1 (fr) * 1989-07-06 1991-10-04 Pechiney Rhenalu Procede d'obtention de materiaux multicouches aptes a etre transformes par emboutissage ou emboutissage-etirage en corps creux
FR2649359B1 (fr) * 1989-07-06 1993-02-12 Cebal Bande ou portion de bande pour emboutissage ou emboutissage-etirage, et son utilisation
US4972037A (en) * 1989-08-07 1990-11-20 Minnesota Mining And Manufacturing Company Polysiloxane-grafted copolymer topical binder composition with novel fluorochemical comonomer and method of coating therewith
US5270305A (en) * 1989-09-08 1993-12-14 Glaxo Group Limited Medicaments
US5208226A (en) * 1989-09-08 1993-05-04 Glaxo Group Limited Medicaments
US5345980A (en) * 1989-09-21 1994-09-13 Glaxo Group Limited Method and apparatus an aerosol container
US5043191A (en) * 1990-02-27 1991-08-27 Miles Inc. Method of protecting hard surfaces
DE4009397A1 (de) * 1990-03-23 1991-09-26 Weidenhammer Packungen Dosenartige verpackung fuer fliessfaehige produkte
US5192548A (en) * 1990-04-30 1993-03-09 Riker Laboratoires, Inc. Device
AU614234B1 (en) * 1990-06-28 1991-08-22 Kabushiki Gaisha Tokai Vessel for aerosol
DE4023909A1 (de) * 1990-07-27 1992-01-30 Wild Rudolf Gmbh & Co Wiederverwendbarer behaelter aus kunststoff sowie seine herstellung und verwendung
GB9024365D0 (en) * 1990-11-09 1991-01-02 Glaxo Group Ltd Medicaments
DE69132258D1 (de) * 1990-11-14 2000-07-27 Titeflex Corp Laminate aus Fluorpolymer und Aluminium
WO1992010549A1 (en) * 1990-12-12 1992-06-25 E.I. Du Pont De Nemours And Company Non-stick coating system with ptfe of different melt viscosities for concentration gradient
WO1992010309A1 (en) * 1990-12-12 1992-06-25 E.I. Du Pont De Nemours And Company Non-stick coating system with ptfe and pfa or fep for concentration gradient
US5168107A (en) * 1990-12-12 1992-12-01 E. I. Du Pont De Nemours And Company Non-stick coating system with PTFE of two low melt viscosities for concentration gradient
GB9027234D0 (en) * 1990-12-15 1991-02-06 Harris Pharma Ltd An inhalation device
EP0499142A3 (en) * 1991-02-09 1993-05-05 Hoechst Aktiengesellschaft Potentiation of the antireactive-antiasthmatic effect of inhaled loop diuretics by inhaled non steroidal anti-flammatory drugs
EP0504112A3 (en) * 1991-03-14 1993-04-21 Ciba-Geigy Ag Pharmaceutical aerosol formulations
RU2027448C1 (ru) 1991-04-25 1995-01-27 Государственное предприятие "ВЭЛТ" Ингалятор
RU2008939C1 (ru) 1991-06-10 1994-03-15 Вячеслав Николаевич Поздняков Физиотерапевтический ингалятор
RU2012362C1 (ru) 1991-06-24 1994-05-15 Юрий Алексеевич Волгин Ингалятор
DE4124730C3 (de) * 1991-07-25 2001-09-06 Ahc Oberflaechentechnik Gmbh Anodisierte Gegenstände aus Aluminium oder Magnesium mit in die Oxidschicht eingelagerten Fluorpolymeren und Verfahren zu deren Herstellung
US5653962A (en) * 1991-12-12 1997-08-05 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicaments
US5736124A (en) * 1991-12-12 1998-04-07 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicament
IL104068A (en) * 1991-12-12 1998-10-30 Glaxo Group Ltd Pharmaceutical preparations in a spray without surfactant containing 1, 1, 1, 2 tetrafluoroethane or 1,1,2,3,3 petafluor N propane as propellant
US5202110A (en) * 1992-01-22 1993-04-13 Virginia Commonwealth University Formulations for delivery of beclomethasone diproprionate by metered dose inhalers containing no chlorofluorocarbon propellants
US5261538A (en) * 1992-04-21 1993-11-16 Glaxo Inc. Aerosol testing method
WO1994000921A1 (en) * 1992-06-25 1994-01-06 Nippondenso Co., Ltd. Mobile object identification device
US5376359A (en) * 1992-07-07 1994-12-27 Glaxo, Inc. Method of stabilizing aerosol formulations
MX9304585A (es) * 1992-07-31 1994-03-31 Glaxo Group Ltd Formulacion farmaceutica en aerosol, lata adecuada para liberar la formulacion e inhalador de dosis dosificada que comprende la lata.
US5250356A (en) * 1992-08-28 1993-10-05 E. I. Du Pont De Nemours And Company Cookware coating system
IT1263783B (it) * 1993-01-21 1996-08-29 Claudio Bignami Formulazioni di prodotti vernicianti per rivestimenti antiaderenti, applicabili mediante rullatura a dischi di alluminio non decapati utilizzabili per lo stampaggio di pentolame domestico
US5411771A (en) * 1993-04-29 1995-05-02 Tsai; Tung-Hung Method for coating metal cookware
JP3093525B2 (ja) 1993-07-02 2000-10-03 九州日本電気株式会社 半導体集積回路
US6596260B1 (en) * 1993-08-27 2003-07-22 Novartis Corporation Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol
US5421492A (en) * 1993-11-02 1995-06-06 Glaxo Inc. Metered aerosol dispensing apparatus and method of use thereof
FR2713299B1 (fr) * 1993-12-01 1996-02-16 Joint Francais Piston étanche et aérosol comportant un tel piston.
US5468798A (en) * 1994-02-18 1995-11-21 Whitford Corporation Basecoat for a coating system
US5447600A (en) * 1994-03-21 1995-09-05 Texas Instruments Polymeric coatings for micromechanical devices
US5508023A (en) * 1994-04-11 1996-04-16 The Center For Innovative Technology Pharmaceutically acceptable agents for solubilizing, wetting, emulsifying, or lubricating in metered dose inhaler formulations which use HFC-227 propellant
US5597433A (en) * 1994-05-27 1997-01-28 Panoramic, Inc. Method and apparatus for manufacturing plastic canisters
DE4434425C2 (de) * 1994-09-27 1997-04-03 Fissler Gmbh Verfahren zur Erzeugung einer Antihaftbeschichtung sowie mit einer solchen versehene Gegenstände
DE19500726C2 (de) * 1995-01-12 1998-07-02 Fraunhofer Ges Forschung Vorrichtung zur Dosierung kleinster Pulvermengen zur Erzeugung eines Aerosols
SK284448B6 (sk) * 1995-04-14 2005-04-01 Glaxo Wellcome Inc. Merací dávkovací inhalátor
CA2218179A1 (en) * 1995-04-14 1996-10-17 Glaxo Wellcome Inc. Metered dose inhaler for beclomethasone dipropionate
SK284447B6 (sk) * 1995-04-14 2005-04-01 Glaxo Wellcome Inc. Merací dávkovací inhalátor
ES2179192T3 (es) * 1995-04-14 2003-01-16 Smithkline Beecham Corp Inhibidor dosificador para albuterol.
US5674592A (en) * 1995-05-04 1997-10-07 Minnesota Mining And Manufacturing Company Functionalized nanostructured films
US5891420A (en) * 1997-04-21 1999-04-06 Aeropharm Technology Limited Environmentally safe triancinolone acetonide aerosol formulations for oral inhalation

Also Published As

Publication number Publication date
EE9700372A (et) 1998-06-15
US6511652B1 (en) 2003-01-28
US6511653B1 (en) 2003-01-28
OA10625A (en) 2001-04-24
TR199701170T1 (xx) 1998-02-21
MX9707878A (es) 1997-11-29
JP2000513237A (ja) 2000-10-10
CA2218179A1 (en) 1996-10-17
PL322781A1 (en) 1998-02-16
EA000889B1 (ru) 2000-06-26
NZ306281A (en) 1999-07-29
IS4581A (is) 1997-10-07
CN1186473A (zh) 1998-07-01
NO974738D0 (no) 1997-10-13
BG102023A (en) 1998-07-31
NO974738L (no) 1997-12-11
JP3573213B2 (ja) 2004-10-06
GEP20002266B (en) 2000-10-25
EA199700230A1 (ru) 1998-02-26
AP9701112A0 (en) 1997-10-31
SK139197A3 (en) 1998-04-08
CZ326197A3 (cs) 1999-06-16
AP835A (en) 2000-05-12
DE69631476T2 (de) 2005-01-13
PL180880B1 (pl) 2001-04-30
HUP9800641A2 (hu) 1998-08-28
ATE258813T1 (de) 2004-02-15
WO1996032345A1 (en) 1996-10-17
EP0820414A1 (de) 1998-01-28
EP0820414B1 (de) 2004-02-04
KR19980703850A (ko) 1998-12-05
US6149892A (en) 2000-11-21
BR9604979A (pt) 1998-06-09
ES2214536T3 (es) 2004-09-16
AU718851B2 (en) 2000-04-20
AU5481296A (en) 1996-10-30
HUP9800641A3 (en) 2001-04-28

Similar Documents

Publication Publication Date Title
DE69631476D1 (de) Vorrichtung zur dosierten inhalierung von beclomethason-diproprionat
DE29501880U1 (de) Vorrichtung zur Knochenverlängerung
DE69826647D1 (de) Akustische vorrichtung zur atemtherapie
DE69508791D1 (de) Intravaginale vorrichtung zur verabreichung von 17beta-oestradiol vorläufer
DE69517169T2 (de) Vorrichtung zur abgabe von medikamenten
DE69535448D1 (de) Vorrichtung zur Unterdrückung von stimulierter Brillouin Streuung
DE69835300D1 (de) Vorrichtung zur inhalation
DE69636694D1 (de) Vorrichtung zur Ablation von Gewebemassen
DE69629739D1 (de) Vorrichtung zur Inspektion von O-Ringen
DE69522019D1 (de) Einteilige Vorrichtung zur Aufbereitung von biologischen Proben
DE59509949D1 (de) Vorrichtung zur strahlteilung
DE59508755D1 (de) Vorrichtung zur rasterstereografischen vermessung von körperoberflächen
DE29701716U1 (de) Vorrichtung zur verbesserten Reinigung von Schuhwerk
DE29618646U1 (de) Vorrichtung zur Entwesung von Gebäuden oder Gebäudeteilen
DE59600130D1 (de) Vorrichtung zur Versorgung von Knochenbrüchen
DE3775029D1 (de) Vorrichtung zur coronaentladungsbehandlung.
DE69623430T2 (de) Vorrichtung zur Bestimmung der Eigenschaften von Knochen
DE29613343U1 (de) Vorrichtung zur Verbesserung der Wirksamkeit von Kondomen
DE29816662U1 (de) Vorrichtung zur Detektion von Atmungserkrankungen
DE9403081U1 (de) Gerät zur Ermittlung von Substituat- und Filtratmengen
DE29505038U1 (de) Vorrichtung zur Behandlung von Atemluft
DE69503800T2 (de) Vorrichtung zur vakuumbeschichtung von schüttgut
DE9415720U1 (de) Vorrichtung zur Oberflächenbehandlung von Schweißnähten
ATA5193A (de) Vorrichtung zur reinigung von zahnärztlichen geräten
DE69430925D1 (de) Vorrichtung zur komplexitätsbestimmung

Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation