DE69633742D1 - Wasserlöslicher komplex aus membranproteinamphiphile acrylpolymer und verwendung zur diagnose - Google Patents

Wasserlöslicher komplex aus membranproteinamphiphile acrylpolymer und verwendung zur diagnose

Info

Publication number
DE69633742D1
DE69633742D1 DE69633742T DE69633742T DE69633742D1 DE 69633742 D1 DE69633742 D1 DE 69633742D1 DE 69633742 T DE69633742 T DE 69633742T DE 69633742 T DE69633742 T DE 69633742T DE 69633742 D1 DE69633742 D1 DE 69633742D1
Authority
DE
Germany
Prior art keywords
amphiphile
diagnosis
water
acrylic polymer
membrane protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69633742T
Other languages
English (en)
Other versions
DE69633742T2 (de
Inventor
Jean-Luc Popot
Christophe Tribet
Roland Audebert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Publication of DE69633742D1 publication Critical patent/DE69633742D1/de
Application granted granted Critical
Publication of DE69633742T2 publication Critical patent/DE69633742T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C08F8/32—Introducing nitrogen atoms or nitrogen-containing groups by reaction with amines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/44—Preparation of metal salts or ammonium salts
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/5432—Liposomes or microcapsules
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815—Carrier is a synthetic polymer
DE69633742T 1996-12-16 1996-12-16 Wasserlöslicher komplex aus membranproteinamphiphile acrylpolymer und verwendung zur diagnose Expired - Lifetime DE69633742T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/FR1996/002009 WO1998027434A1 (fr) 1996-12-16 1996-12-16 Complexe hydrosoluble proteine membranaire-polymere acrylique a caractere amphiphile et application aux methodes de diagnostic

Publications (2)

Publication Number Publication Date
DE69633742D1 true DE69633742D1 (de) 2004-12-02
DE69633742T2 DE69633742T2 (de) 2005-11-03

Family

ID=9489337

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69633742T Expired - Lifetime DE69633742T2 (de) 1996-12-16 1996-12-16 Wasserlöslicher komplex aus membranproteinamphiphile acrylpolymer und verwendung zur diagnose

Country Status (5)

Country Link
US (1) US6492501B1 (de)
EP (1) EP0946875B1 (de)
JP (1) JP2001519836A (de)
DE (1) DE69633742T2 (de)
WO (1) WO1998027434A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7232861B2 (en) * 2000-09-12 2007-06-19 Koji Sode Enzyme-mimicking polymers
FR2908414B1 (fr) 2006-11-13 2012-01-20 Centre Nat Rech Scient Immobilisation de proteines membranaires sur un support par l'intermediaire d'une molecule amphiphile
WO2009105624A2 (en) * 2008-02-21 2009-08-27 Massachusetts Institute Of Technology Simultaneous delivery of receptors and/or co-receptors for growth factor stability and activity
FR2952642B1 (fr) 2009-11-16 2012-01-06 Centre Nat Rech Scient Polymeres comprenant une majorite de monomeres amphiphiles destines au piegeage et a la manipulation de proteines membranaires
US10175183B2 (en) 2011-03-31 2019-01-08 Kunimine Industries Co., Ltd. Agent for searching for protein crystallization conditions and method of searching for protein crystallization conditions
FR3045834B1 (fr) 2015-12-21 2021-03-05 Biomerieux Sa Diluant de reactifs pour immunoessai
FR3063730B1 (fr) * 2017-03-09 2021-09-17 Centre Nat Rech Scient Composes-clips surfactants pour l'extraction et la stabilisation en solution de proteines membranaires
JP2022513711A (ja) 2018-12-03 2022-02-09 セントレ ナシオナル デ ラ ルシェルシェ シエンティフィーク アンフィポール
JPWO2022211006A1 (de) * 2021-03-31 2022-10-06

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH665565A5 (de) * 1983-10-22 1988-05-31 Mitsui Toatsu Chemicals Verfahren zur steuerung der konzentration einer eine makromolekulare verbindung enthaltenden waessrigen loesung oder emulsion.
FR2615194B1 (fr) * 1987-05-11 1991-06-14 Rhone Poulenc Chimie Particules de polymere comportant, implantees a leur surface des molecules amphiphiles portant des groupes ionogenes ou reactifs, leur procede de preparation et leur application en biologie
EP0363106B1 (de) * 1988-10-07 1995-05-31 Johnson & Johnson Clinical Diagnostics, Inc. Verwendung eines kationischen Oberflächenaktivmittels zur Extraktion des Hauptprotein-Antigens der äusseren Membran von Chlamydia
US5223411A (en) * 1990-05-14 1993-06-29 Centre National De La Recherche Scientifique (Cnrs) Nonionic surfactants having a carbamoyl group and process for treatment of a proteins containing medium using the same
US5681811A (en) * 1993-05-10 1997-10-28 Protein Delivery, Inc. Conjugation-stabilized therapeutic agent compositions, delivery and diagnostic formulations comprising same, and method of making and using the same
US6172262B1 (en) * 1999-01-27 2001-01-09 Wisconsin Alumni Research Foundation Amphiphilic agents for membrane protein solubilization

Also Published As

Publication number Publication date
WO1998027434A1 (fr) 1998-06-25
EP0946875A1 (de) 1999-10-06
US6492501B1 (en) 2002-12-10
EP0946875B1 (de) 2004-10-27
DE69633742T2 (de) 2005-11-03
JP2001519836A (ja) 2001-10-23

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