DE69634054D1 - Kristaline (R-(R*,R*))-2-(4-Fluorphenyl)-Beta,Delta-Dihydroxy-5-(1-Methylethyl)-3-Phenyl-4-((Phenylamino)Carbonyl)-1H-Pyrrol-1-Heptancarbonsäure Hemi Calcium Sslz (Atorvastatin) - Google Patents

Kristaline (R-(R*,R*))-2-(4-Fluorphenyl)-Beta,Delta-Dihydroxy-5-(1-Methylethyl)-3-Phenyl-4-((Phenylamino)Carbonyl)-1H-Pyrrol-1-Heptancarbonsäure Hemi Calcium Sslz (Atorvastatin)

Info

Publication number
DE69634054D1
DE69634054D1 DE69634054T DE69634054T DE69634054D1 DE 69634054 D1 DE69634054 D1 DE 69634054D1 DE 69634054 T DE69634054 T DE 69634054T DE 69634054 T DE69634054 T DE 69634054T DE 69634054 D1 DE69634054 D1 DE 69634054D1
Authority
DE
Germany
Prior art keywords
sslz
kristaline
atorvastatin
pyrrol
phenylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69634054T
Other languages
English (en)
Other versions
DE69634054T2 (de
Inventor
Christopher A Briggs
Rex Allen Jennings
Robert A Wade
Kikuko Harasawa
Shigeru Ichikawa
Kazuo Minohara
Shinsuke Nakagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21696090&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69634054(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of DE69634054D1 publication Critical patent/DE69634054D1/de
Application granted granted Critical
Publication of DE69634054T2 publication Critical patent/DE69634054T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69634054T 1995-07-17 1996-07-08 Kristalline (R-(R*, R*))-2-(4-Fluorophenyl)-β, δ-Dihydroxy-5-(1-Methylethyl)-3-Phenyl-4-((Phenylamino)Carbonyl)-1H-Pyrrol-1-Heptancarbonsäure Hemi Calcium Salz (Atorvastatin) Expired - Lifetime DE69634054T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US145295P 1995-07-17 1995-07-17
US1452P 1995-07-17

Publications (2)

Publication Number Publication Date
DE69634054D1 true DE69634054D1 (de) 2005-01-20
DE69634054T2 DE69634054T2 (de) 2005-12-08

Family

ID=21696090

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69634054T Expired - Lifetime DE69634054T2 (de) 1995-07-17 1996-07-08 Kristalline (R-(R*, R*))-2-(4-Fluorophenyl)-β, δ-Dihydroxy-5-(1-Methylethyl)-3-Phenyl-4-((Phenylamino)Carbonyl)-1H-Pyrrol-1-Heptancarbonsäure Hemi Calcium Salz (Atorvastatin)
DE69616808T Revoked DE69616808T2 (de) 1995-07-17 1996-07-08 Kristallines (r-(r*,r*))-2-(4-fluorphenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-1h-pyrrol-1-heptancarbonsäure hemi calcium salz (atorvastatin)

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69616808T Revoked DE69616808T2 (de) 1995-07-17 1996-07-08 Kristallines (r-(r*,r*))-2-(4-fluorphenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-1h-pyrrol-1-heptancarbonsäure hemi calcium salz (atorvastatin)

Country Status (38)

Country Link
US (1) US5969156A (de)
EP (2) EP1148049B1 (de)
JP (4) JP3296564B2 (de)
KR (2) KR100431038B1 (de)
CN (1) CN1087288C (de)
AR (2) AR003458A1 (de)
AT (3) ATE284868T1 (de)
AU (1) AU725424B2 (de)
BG (1) BG63630B1 (de)
BR (1) BR9609872A (de)
CA (1) CA2220018C (de)
CO (1) CO4700443A1 (de)
CY (1) CY2358B1 (de)
CZ (3) CZ294695B6 (de)
DE (2) DE69634054T2 (de)
DK (2) DK0848705T3 (de)
EA (1) EA000474B1 (de)
EE (1) EE03606B1 (de)
ES (2) ES2167587T3 (de)
GE (1) GEP20002029B (de)
HK (1) HK1018052A1 (de)
HR (1) HRP960339B1 (de)
HU (1) HU223599B1 (de)
IL (7) IL128862A (de)
MX (1) MX9709099A (de)
NO (1) NO309898B1 (de)
NZ (1) NZ312907A (de)
PE (1) PE1898A1 (de)
PL (1) PL193479B1 (de)
PT (2) PT1148049E (de)
RO (1) RO120070B1 (de)
SI (2) SI0848705T1 (de)
SK (1) SK284202B6 (de)
TW (1) TW486467B (de)
UA (1) UA51661C2 (de)
UY (2) UY24285A1 (de)
WO (1) WO1997003959A1 (de)
ZA (1) ZA966044B (de)

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