DE69635517D1 - Menschliche neuronale acetylcholin-rezeptor verbindungen und methoden zu deren anwendung - Google Patents
Menschliche neuronale acetylcholin-rezeptor verbindungen und methoden zu deren anwendungInfo
- Publication number
- DE69635517D1 DE69635517D1 DE69635517T DE69635517T DE69635517D1 DE 69635517 D1 DE69635517 D1 DE 69635517D1 DE 69635517 T DE69635517 T DE 69635517T DE 69635517 T DE69635517 T DE 69635517T DE 69635517 D1 DE69635517 D1 DE 69635517D1
- Authority
- DE
- Germany
- Prior art keywords
- alpha
- subunits
- beta
- human neuronal
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US484722 | 1995-06-07 | ||
US08/484,722 US6485967B1 (en) | 1995-06-07 | 1995-06-07 | Human neuronal nicotinic acetylcholine receptor α6 and β3 nucleic acid |
PCT/US1996/009775 WO1996041876A1 (en) | 1995-06-07 | 1996-06-07 | Human neuronal nicotinic acetylcholine receptor compositions and methods employing same |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69635517D1 true DE69635517D1 (de) | 2006-01-05 |
DE69635517T2 DE69635517T2 (de) | 2006-08-10 |
Family
ID=23925332
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69635517T Expired - Fee Related DE69635517T2 (de) | 1995-06-07 | 1996-06-07 | Menschliche neuronale acetylcholin-rezeptor verbindungen und methoden zu deren anwendung |
Country Status (9)
Country | Link |
---|---|
US (5) | US6485967B1 (de) |
EP (2) | EP1295945A1 (de) |
JP (2) | JPH11509726A (de) |
AT (1) | ATE311448T1 (de) |
AU (1) | AU704927B2 (de) |
CA (1) | CA2221311A1 (de) |
DE (1) | DE69635517T2 (de) |
ES (1) | ES2250993T3 (de) |
WO (1) | WO1996041876A1 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6632823B1 (en) | 1997-12-22 | 2003-10-14 | Merck & Co., Inc. | Substituted pyridine compounds useful as modulators of acetylcholine receptors |
DE19819829A1 (de) | 1998-05-04 | 1999-11-11 | Bayer Ag | Nukleinsäuren, die für Acetylcholinrezeptor-Untereinheiten von Insekten kodieren |
GB9913248D0 (en) * | 1999-06-09 | 1999-08-04 | Babraham Inst | Recombinant nematode nicotinic receptor and uses |
EP1090991A1 (de) * | 1999-09-29 | 2001-04-11 | Sanofi-Synthelabo | Nikotin-acetylcholin-Rezeptor, dessen Isolierung und Verwendung |
DE19959582A1 (de) * | 1999-12-10 | 2001-06-13 | Bayer Ag | Nukleinsäuren, die für neue Acetylcholinrezeptor-beta-Untereinheiten von Insekten kodieren |
WO2001044283A2 (en) * | 1999-12-14 | 2001-06-21 | Pharmacia & Upjohn Company | Human ion channels |
AU2001249650A1 (en) * | 2000-04-03 | 2001-10-15 | Anne Chew | Haplotypes of the chrnb3 gene |
FR2813499B1 (fr) * | 2000-09-04 | 2004-11-26 | Pasteur Institut | Mammifere non-humain mutant pour l'expression de la sous- unite alpha6 du recepteur nicotinique de l'acetylcholine et utilisation pour le criblage de substances susceptibles d'interagir avec ce recepteur |
AU2002324842C9 (en) | 2001-08-31 | 2008-07-10 | Agensys, Inc. | 205P1B5 in treatment and detection of cancer |
WO2005030145A2 (en) * | 2003-09-24 | 2005-04-07 | Targacept, Inc. | Composition and pharmacology of novel alpha-6-containing nicotinic acetylcholine receptors |
US7799683B2 (en) * | 2004-11-08 | 2010-09-21 | Tel Epion, Inc. | Copper interconnect wiring and method and apparatus for forming thereof |
US20070184656A1 (en) * | 2004-11-08 | 2007-08-09 | Tel Epion Inc. | GCIB Cluster Tool Apparatus and Method of Operation |
CN101180543B (zh) * | 2005-02-23 | 2014-06-18 | 美国陶氏益农公司 | 使用烟碱乙酰胆碱受体亚单位的新检测方法 |
US7879913B2 (en) * | 2005-06-28 | 2011-02-01 | Catholic Healthcare West | Iptakalim hydrochloride for decreasing nicotine use |
US9005981B2 (en) * | 2008-12-30 | 2015-04-14 | Dow Agrosciences Llc | Assays utilizing nicotinic acetylcholine receptor subunits |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4703008A (en) | 1983-12-13 | 1987-10-27 | Kiren-Amgen, Inc. | DNA sequences encoding erythropoietin |
US4837148A (en) | 1984-10-30 | 1989-06-06 | Phillips Petroleum Company | Autonomous replication sequences for yeast strains of the genus pichia |
US4855231A (en) | 1984-10-30 | 1989-08-08 | Phillips Petroleum Company | Regulatory region for heterologous gene expression in yeast |
US4882279A (en) | 1985-10-25 | 1989-11-21 | Phillips Petroleum Company | Site selective genomic modification of yeast of the genus pichia |
US4859609A (en) | 1986-04-30 | 1989-08-22 | Genentech, Inc. | Novel receptors for efficient determination of ligands and their antagonists or agonists |
US5071773A (en) | 1986-10-24 | 1991-12-10 | The Salk Institute For Biological Studies | Hormone receptor-related bioassays |
US5024939A (en) | 1987-07-09 | 1991-06-18 | Genentech, Inc. | Transient expression system for producing recombinant protein |
US4929555A (en) | 1987-10-19 | 1990-05-29 | Phillips Petroleum Company | Pichia transformation |
US4981784A (en) | 1987-12-02 | 1991-01-01 | The Salk Institute For Biological Studies | Retinoic acid receptor method |
US5449606A (en) | 1988-03-18 | 1995-09-12 | The Salk Institute For Biological Studies | DNA encoding neuronal nicotinic acetylcholine receptor compositions containing the beta 4 subunit |
CA1341554C (en) | 1988-03-18 | 2007-10-09 | The Salk Institute For Biological Studies | Neuronal nicotinic acetylcholine receptor compositions and assay |
CA1341170C (en) | 1988-04-04 | 2001-01-16 | Steven B. Ellis | Calcium channel compositions and methods |
US5386025A (en) | 1990-02-20 | 1995-01-31 | The Salk Institute Biotechnology/Industrial Associates | Calcium channel compositions and methods |
CA2047683C (en) | 1989-03-14 | 2000-06-06 | Stephen F. Heinemann | Neuronal nicotinic acetylcholine receptor compositions containing the beta 4 subunit |
AU648523B2 (en) | 1989-10-25 | 1994-04-28 | Salk Institute For Biological Studies, The | Receptor infection assay |
US5091518A (en) | 1989-11-16 | 1992-02-25 | The Salk Institute For Biological Studies | Beta retinoic acid response elements compositions and assays |
US5369028A (en) | 1990-04-03 | 1994-11-29 | The Salk Institute Biotechnology/Industrial Associates, Inc. | DNA and mRNA encoding human neuronal nicotinic acetylcholine receptor compositions and cells transformed with same |
US5401629A (en) | 1990-08-07 | 1995-03-28 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Assay methods and compositions useful for measuring the transduction of an intracellular signal |
EP0688361B1 (de) * | 1993-03-08 | 2004-10-13 | Merck & Co., Inc. | Menschliche neuronale nikotin-acetylcholin-rezeptor-verbindungen und methoden ihres einsatzes |
WO1995013299A1 (en) | 1993-11-08 | 1995-05-18 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Human neuronal nicotinic acetylcholine receptor compositions and methods employing same |
-
1995
- 1995-06-07 US US08/484,722 patent/US6485967B1/en not_active Expired - Fee Related
-
1996
- 1996-06-07 DE DE69635517T patent/DE69635517T2/de not_active Expired - Fee Related
- 1996-06-07 WO PCT/US1996/009775 patent/WO1996041876A1/en active IP Right Grant
- 1996-06-07 EP EP02078642A patent/EP1295945A1/de not_active Withdrawn
- 1996-06-07 AU AU62664/96A patent/AU704927B2/en not_active Ceased
- 1996-06-07 ES ES96921440T patent/ES2250993T3/es not_active Expired - Lifetime
- 1996-06-07 AT AT96921440T patent/ATE311448T1/de not_active IP Right Cessation
- 1996-06-07 EP EP96921440A patent/EP0832230B1/de not_active Expired - Lifetime
- 1996-06-07 US US08/660,451 patent/US6524789B1/en not_active Expired - Fee Related
- 1996-06-07 JP JP9503220A patent/JPH11509726A/ja not_active Withdrawn
- 1996-06-07 CA CA002221311A patent/CA2221311A1/en not_active Abandoned
-
2002
- 2002-11-25 US US10/303,198 patent/US7169895B2/en not_active Expired - Fee Related
-
2003
- 2003-01-23 US US10/349,836 patent/US7119067B2/en not_active Expired - Fee Related
-
2007
- 2007-01-29 US US11/699,270 patent/US20070185313A1/en not_active Abandoned
-
2008
- 2008-10-03 JP JP2008258987A patent/JP2009050270A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US7169895B2 (en) | 2007-01-30 |
US6524789B1 (en) | 2003-02-25 |
US20040002122A1 (en) | 2004-01-01 |
EP0832230B1 (de) | 2005-11-30 |
AU704927B2 (en) | 1999-05-06 |
EP0832230A1 (de) | 1998-04-01 |
JP2009050270A (ja) | 2009-03-12 |
WO1996041876A1 (en) | 1996-12-27 |
DE69635517T2 (de) | 2006-08-10 |
EP1295945A1 (de) | 2003-03-26 |
ATE311448T1 (de) | 2005-12-15 |
US6485967B1 (en) | 2002-11-26 |
CA2221311A1 (en) | 1996-12-27 |
ES2250993T3 (es) | 2006-04-16 |
US7119067B2 (en) | 2006-10-10 |
US20070185313A1 (en) | 2007-08-09 |
AU6266496A (en) | 1997-01-09 |
JPH11509726A (ja) | 1999-08-31 |
US20030138911A1 (en) | 2003-07-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: MERCK & CO., INC., RAHWAY, N.J., US |
|
8339 | Ceased/non-payment of the annual fee |