DE69636889D1 - Öladjuvierter Impfstoff und Verfahren zu seiner Herstellung - Google Patents

Öladjuvierter Impfstoff und Verfahren zu seiner Herstellung

Info

Publication number
DE69636889D1
DE69636889D1 DE69636889T DE69636889T DE69636889D1 DE 69636889 D1 DE69636889 D1 DE 69636889D1 DE 69636889 T DE69636889 T DE 69636889T DE 69636889 T DE69636889 T DE 69636889T DE 69636889 D1 DE69636889 D1 DE 69636889D1
Authority
DE
Germany
Prior art keywords
weight
oil
water
oil adjuvant
adjuvant vaccine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69636889T
Other languages
English (en)
Other versions
DE69636889T2 (de
Inventor
Tokuji Miyahara
Kozo Takase
Koichi Saito
Yoko Kishimoto
Satoru Tokuyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemo Sero Therapeutic Research Institute Kaketsuken
NOF Corp
Original Assignee
Chemo Sero Therapeutic Research Institute Kaketsuken
NOF Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Sero Therapeutic Research Institute Kaketsuken, NOF Corp filed Critical Chemo Sero Therapeutic Research Institute Kaketsuken
Publication of DE69636889D1 publication Critical patent/DE69636889D1/de
Application granted granted Critical
Publication of DE69636889T2 publication Critical patent/DE69636889T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
DE69636889T 1995-11-30 1996-11-29 Öladjuvierter Impfstoff und Verfahren zu seiner Herstellung Expired - Fee Related DE69636889T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP31196495 1995-11-30
JP31196495 1995-11-30
JP31196595 1995-11-30
JP31196595 1995-11-30

Publications (2)

Publication Number Publication Date
DE69636889D1 true DE69636889D1 (de) 2007-03-22
DE69636889T2 DE69636889T2 (de) 2007-12-06

Family

ID=26566969

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69636889T Expired - Fee Related DE69636889T2 (de) 1995-11-30 1996-11-29 Öladjuvierter Impfstoff und Verfahren zu seiner Herstellung

Country Status (9)

Country Link
US (1) US5814321A (de)
EP (1) EP0781559B1 (de)
KR (1) KR100512030B1 (de)
CN (1) CN1196473C (de)
AT (1) ATE353225T1 (de)
DE (1) DE69636889T2 (de)
DK (1) DK0781559T3 (de)
ES (1) ES2277339T3 (de)
TW (1) TW410158B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9626865D0 (en) * 1996-12-24 1997-02-12 Cyanamid Websters Pty Limited Veterinary vaccines
IS4518A (is) 1997-07-09 1999-01-10 Lyfjathroun Hf, The Icelandic Bio Pharmaceutical Group Nýtt lyfjaform fyrir bóluefni
WO1999020305A1 (en) * 1997-10-17 1999-04-29 Fort Dodge Australia Pty. Limited Veterinary vaccines
US6225289B1 (en) 1998-12-10 2001-05-01 Genvec, Inc. Methods and compositions for preserving adenoviral vectors
AU769539B2 (en) 1999-01-29 2004-01-29 Zoetis Services Llc Adjuvants for use in vaccines
JP2001131087A (ja) * 1999-11-05 2001-05-15 Chemo Sero Therapeut Res Inst オイルアジュバントワクチン
EP1104767A1 (de) * 1999-11-30 2001-06-06 Stichting Dienst Landbouwkundig Onderzoek Mono- und Disaccharidederivate die sowohl Fettsäureestern als Sulfatestern enthalten
ATE320267T1 (de) * 2000-08-11 2006-04-15 Lohmann Animal Health Gmbh W/o emulsion adjuvanszuzammensetzungen für impstoffen
DE10113284A1 (de) * 2001-03-16 2002-10-02 Heinrich Exner Adjuvans-Emulsion und Verfahren zu deren Verwendung
IL142536A0 (en) * 2001-04-11 2002-03-10 Yeda Res & Dev Carriers for therapeutic preparations for treatment of t-cell mediated diseases
US20040241310A1 (en) * 2001-08-16 2004-12-02 Sveibjorn Gizurarson Method of producing antibodies ex-vivo
UY27412A1 (es) * 2002-08-12 2003-06-30 Carlson Internat Inc Un nuevo producto para el combate de garrapatas y el proceso para la prepaacinn.
CU23476A1 (es) * 2004-01-29 2009-12-17 Ct Ingenieria Genetica Biotech Formulación adyuvante conteniendo una emulsión oleosa con aceite de jojoba
FR2878746B1 (fr) * 2004-12-02 2007-02-23 Vetoquinol Sa Sa Nouvelle composition pharmaceutique utilisable dans le domaine des vaccins
CN1320924C (zh) * 2005-01-07 2007-06-13 邢为藩 一种自乳化疫苗佐剂及其制备方法
EP1844789B8 (de) * 2005-01-19 2014-10-08 Sumitomo Dainippon Pharma Co., Ltd. Emulgierte zusammensetzung zur verdünnung und krebsimpfstoff-zusammensetzung
EA014314B1 (ru) * 2005-08-02 2010-10-29 Новартис Вэксинес Энд Дайэгностикс Срл Пониженная интерференция между маслосодержащими адъювантами и антигенами, содержащими поверхностно-активные вещества
EP1934605B1 (de) * 2005-09-22 2014-03-26 Prosci Incorporated In hefemutanten produzierte glykosylierte polypeptide und verwendungsverfahren dafür
US20070292521A1 (en) * 2006-06-20 2007-12-20 Schwitzer Co., Ltd Oral Encapsulated Preparation for Aquatic Animals
JP5135852B2 (ja) * 2007-03-30 2013-02-06 日油株式会社 可溶化用組成物
US8735359B2 (en) 2012-05-24 2014-05-27 Orban Biotech Llc Combinations of modalities for the treatment of diabetes
KR20150033703A (ko) 2012-06-27 2015-04-01 오르반 바이오테크 엘엘씨 당뇨병 치료를 위한 ctla4 융합 단백질
CN103223164B (zh) * 2013-04-15 2014-08-20 华南农业大学 一种水包油包水型佐剂疫苗及其制备方法
GB2523399B (en) 2014-02-25 2019-03-13 Orban Tihamer A composition comprising ten overlapping peptide fragments of the entire preproinsulin sequence
JP6789631B2 (ja) 2015-12-22 2020-11-25 ロレアル Spf及びレオロジーを改善するための高内相エマルション組成物
CN108578688B (zh) * 2018-04-03 2022-02-11 武汉轻工大学 多重纳米乳疫苗佐剂的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2313078A1 (fr) * 1975-02-07 1976-12-31 Anvar Composition a base d'huile vegetale metabolisable et d'eau, utilisable notamment pour la constitution de preparations adjuvantes, ces preparations adjuvantes et leur procede d'obtention
US4933179A (en) * 1983-08-22 1990-06-12 Syntex (U.S.A.) Inc. Feline leukemia virus antigen vaccines
US4606918A (en) * 1983-08-22 1986-08-19 Syntex (U.S.A.) Inc. Polyoxypropylene-polyoxyethylene block polymer based adjuvants
JPS60199833A (ja) * 1984-03-26 1985-10-09 Meiji Milk Prod Co Ltd 医薬品、化粧品等用w/o/w型複合エマルジヨンの製造法
JPH0647533B2 (ja) * 1984-08-10 1994-06-22 裕 水島 4−ビフエニリル酢酸系化合物含有脂肪乳剤
SE8505047L (sv) * 1985-10-25 1987-04-26 Nutritional Int Res Inst Fettemulsion
FR2649013B1 (fr) * 1989-07-03 1991-10-25 Seppic Sa Vaccins et vecteurs de principes actifs fluides contenant une huile metabolisable
FR2649012B1 (fr) * 1989-07-03 1991-10-25 Seppic Sa Emulsions multiphasiques injectables
EP0580778B1 (de) * 1991-04-19 1999-08-11 LDS Technologies, Inc. Konvertierbare mikroemulsionsverbindungen
JP2913229B2 (ja) * 1991-10-21 1999-06-28 塩野義製薬株式会社 油性アジュバントワクチン製剤
JPH0681731A (ja) * 1992-03-31 1994-03-22 Frontier Maaketeingu:Kk 内燃機関等の燃焼用空気の改質装置
JP3095537B2 (ja) * 1992-07-27 2000-10-03 松下電工株式会社 汚水処理装置
JPH06172216A (ja) * 1992-12-04 1994-06-21 Norin Suisanshiyou Kachiku Eisei Shikenjo 乳液状オイルアジュバント
FR2702373B1 (fr) * 1993-03-08 1996-06-07 Rhone Merieux Emulsions vaccinales fluides eau-dans-l'huile contenant une huile métabolisable.

Also Published As

Publication number Publication date
CN1196473C (zh) 2005-04-13
DK0781559T3 (da) 2007-02-26
TW410158B (en) 2000-11-01
ES2277339T3 (es) 2007-07-01
EP0781559A3 (de) 1998-12-16
ATE353225T1 (de) 2007-02-15
DE69636889T2 (de) 2007-12-06
KR100512030B1 (ko) 2005-11-24
CN1159914A (zh) 1997-09-24
US5814321A (en) 1998-09-29
KR970025624A (ko) 1997-06-24
EP0781559A2 (de) 1997-07-02
EP0781559B1 (de) 2007-02-07

Similar Documents

Publication Publication Date Title
DE69636889D1 (de) Öladjuvierter Impfstoff und Verfahren zu seiner Herstellung
US5292503A (en) Stable water in oil emulsions
JP3007142B2 (ja) 代謝可能な油を含有する液体ワクチンおよび活性成分担体
CA2135192C (en) Vaccinal fluid water-in-oil emulsions containing a metabolizable oil
WO2007092085A3 (en) Fragranced therapeutic delivery system
JPH09505065A (ja) セラミド化粧品組成物
ATE218359T1 (de) Neue zubereitungsformen des cyclosporins zur oralen applikation mit einfacher zusammensetzung und hoher bioverfügbarkeit und verfahren zu deren herstellung
JP2011178667A (ja) 皮膚用乳化組成物
JP2001518886A (ja) 損傷した皮膚の脂質構造のラメラ性を再構成するための水中油型エマルジョン
IE49527B1 (en) Preparing compositions comprising isosorbide dinitrate
JP2007153858A (ja) 水中油型乳化化粧料
US8178584B2 (en) Water-in oil emulsified composition
JP2003055128A (ja) 透明化粧料組成物
JP4780836B2 (ja) 水中油型皮膚用乳化化粧料
JP5002124B2 (ja) ポリグリセリン脂肪酸エステル
JP3942531B2 (ja) 透明自己乳化型油性化粧料
US6165481A (en) Highly pure squalane, raw material for pharmaceuticals and cosmetics prepared by using the same and method for producing the same
JP2002003339A (ja) 多層型組成物
US7182940B1 (en) Shea butter esters
JP3755988B2 (ja) 乳化安定化剤
JP3235673B2 (ja) 油中水型乳化組成物
JPS63119844A (ja) 油中水型乳化組成物
JP2001025654A (ja) 界面活性助剤
JPH09175936A (ja) クレンジング用組成物
JPH0699304B2 (ja) 3―オキシゲルミルプロピオン酸を有効成分とする外用剤

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee