DE69637534D1 - Verfahren zur herstellung einer undifferenzierten zell - Google Patents

Verfahren zur herstellung einer undifferenzierten zell

Info

Publication number
DE69637534D1
DE69637534D1 DE69637534T DE69637534T DE69637534D1 DE 69637534 D1 DE69637534 D1 DE 69637534D1 DE 69637534 T DE69637534 T DE 69637534T DE 69637534 T DE69637534 T DE 69637534T DE 69637534 D1 DE69637534 D1 DE 69637534D1
Authority
DE
Germany
Prior art keywords
undifferenced
cell
producing
undifferenced cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69637534T
Other languages
English (en)
Inventor
Ilham Mohamed Abuljadayel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tristem Trading Cyprus Ltd
Original Assignee
Tristem Trading Cyprus Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tristem Trading Cyprus Ltd filed Critical Tristem Trading Cyprus Ltd
Application granted granted Critical
Publication of DE69637534D1 publication Critical patent/DE69637534D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/06—Anti-neoplasic drugs, anti-retroviral drugs, e.g. azacytidine, cyclophosphamide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
DE69637534T 1995-02-02 1996-01-31 Verfahren zur herstellung einer undifferenzierten zell Expired - Lifetime DE69637534D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9502022.8A GB9502022D0 (en) 1995-02-02 1995-02-02 A method for preparing lymphohaematopoietic progenitor cells
PCT/GB1996/000208 WO1996023870A1 (en) 1995-02-02 1996-01-31 A method of preparing an undifferentiated cell

Publications (1)

Publication Number Publication Date
DE69637534D1 true DE69637534D1 (de) 2008-07-03

Family

ID=10768971

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69637534T Expired - Lifetime DE69637534D1 (de) 1995-02-02 1996-01-31 Verfahren zur herstellung einer undifferenzierten zell

Country Status (23)

Country Link
US (3) US6090625A (de)
EP (1) EP0807166B1 (de)
JP (4) JPH10513053A (de)
KR (1) KR100630591B1 (de)
CN (1) CN1289660C (de)
AP (1) AP693A (de)
AT (1) ATE396253T1 (de)
AU (1) AU4545196A (de)
BR (1) BR9606866A (de)
CA (1) CA2211147C (de)
CY (1) CY2206B1 (de)
DE (1) DE69637534D1 (de)
DK (1) DK0807166T3 (de)
ES (1) ES2308774T3 (de)
GB (1) GB9502022D0 (de)
HK (1) HK1017710A1 (de)
IL (2) IL139244A (de)
NZ (1) NZ300650A (de)
PT (1) PT807166E (de)
RU (2) RU2177996C2 (de)
SI (1) SI0807166T1 (de)
WO (1) WO1996023870A1 (de)
ZA (1) ZA96727B (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9068164B1 (en) 1995-02-02 2015-06-30 Tristem Trading (Cyprus) Limited Method of preparing an undifferentiated cell
GB9502022D0 (en) * 1995-02-02 1995-03-22 Abuljadayel Ilham M S A method for preparing lymphohaematopoietic progenitor cells
JP5398941B2 (ja) 1999-08-05 2014-01-29 エイビーティー ホールディング カンパニー 多能性成体幹細胞およびそれを単離する方法
US8075881B2 (en) * 1999-08-05 2011-12-13 Regents Of The University Of Minnesota Use of multipotent adult stem cells in treatment of myocardial infarction and congestive heart failure
US10638734B2 (en) 2004-01-05 2020-05-05 Abt Holding Company Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
US8609412B2 (en) * 1999-08-05 2013-12-17 Regents Of The University Of Minnesota Mapc generation of lung tissue
US7015037B1 (en) 1999-08-05 2006-03-21 Regents Of The University Of Minnesota Multiponent adult stem cells and methods for isolation
US8252280B1 (en) 1999-08-05 2012-08-28 Regents Of The University Of Minnesota MAPC generation of muscle
US7927587B2 (en) 1999-08-05 2011-04-19 Regents Of The University Of Minnesota MAPC administration for the treatment of lysosomal storage disorders
NL1017973C2 (nl) * 2000-05-10 2002-11-08 Tristem Trading Cyprus Ltd Inrichting.
CN101386839A (zh) * 2000-05-10 2009-03-18 特里施泰姆贸易(塞浦路斯)有限公司 一种设备
EP1367899A4 (de) * 2001-02-14 2004-07-28 Leo T Furcht Multipotente adulte stammzellen, ausgangsmaterial dafür, verfahren zu ihrer gewinnung und erhaltung, differenzierungsmethoden dafür, verfahren zu ihrer verwendung, sowie von ihnen stammende zellen
DE10144326B4 (de) * 2001-09-10 2005-09-22 Siemens Ag Verfahren und System zur Überwachung eines Reifenluftdrucks
TWI288779B (en) * 2002-03-28 2007-10-21 Blasticon Biotech Forschung Dedifferentiated, programmable stem cells of monocytic origin, and their production and use
DE10231655A1 (de) * 2002-07-12 2004-02-26 Blasticon Biotechnologische Forschung Gmbh Transplantat-Akzeptanz induzierende Zellen monozytären Ursprungs, sowie deren Herstellung und Verwendung
WO2004050859A2 (en) 2002-11-27 2004-06-17 Regents Of The University Of Minnesota Homologous recombination in multipotent adult progenitor cells
AU2004256154A1 (en) * 2003-07-11 2005-01-20 Blasticon Biotechnologische Forschung Gmbh Autologous self-tolerance inducing cells of monocytic origin and their use in pharmaceutical proparations
AU2004262451B2 (en) 2003-08-12 2009-11-26 Tigenix N.V. Use of CXCL6 chemokine in the prevention or repair of cartilage defects
AU2004296848A1 (en) 2003-12-04 2005-06-23 Regents Of The University Of Minnesota Compositions and methods for the treatment of lysosomal storage disorders
WO2006047743A2 (en) * 2004-10-26 2006-05-04 Regents Of The University Of Minnesota Swine multipotent adult progenitor cells
WO2006086639A1 (en) * 2005-02-10 2006-08-17 Regents Of The University Of Minnesota Vascular/lymphatic endothelial cells
US20080311084A1 (en) * 2005-05-05 2008-12-18 Verfaillie Catherine M Mapc Engraftment in the Hematopoietic System
AU2005331559B2 (en) * 2005-05-05 2012-04-19 Regents Of The University Of Minnesota Use of NK cell inhibition to facilitate persistence of engrafted MHC-I negative cells
US20080194024A1 (en) * 2005-07-29 2008-08-14 Mays Robert W Culture of Non-Embryonic Cells at High Cell Density
EP1941032A2 (de) * 2005-10-14 2008-07-09 Regents Of The University Of Minnesota Differenzierung nichtembryonaler stammzellen zu zellen mit einem pankreatischen phänotyp
CA2670497A1 (en) * 2006-11-24 2008-05-29 Regents Of The University Of Minnesota Endodermal progenitor cells
EP2245141B1 (de) * 2008-01-18 2018-03-14 Regents of the University of Minnesota Stammzellenaggregate und verfahren zur herstellung und verwendung
EP2362899A1 (de) 2008-10-31 2011-09-07 Katholieke Universiteit Leuven Optimierte verfahren zur differenzierung von zellen zu zellen mit hepatozyt- und hepatozytenvorläufer-phänotypen, mit den verfahren produzierte zellen und verfahren zur verwendung der zellen
CN102459575A (zh) 2009-06-05 2012-05-16 细胞动力国际有限公司 重编程t细胞和造血细胞的方法
DK2456853T3 (da) * 2009-07-21 2021-02-01 Abt Holding Co Anvendelse af stamceller til reduktion af leukocyt-ekstravasation
SG10201913618WA (en) * 2009-07-21 2020-03-30 Abt Holding Co Use of stem cells to reduce leukocyte extravasation
RU2661107C1 (ru) * 2009-09-15 2018-07-11 Зэ Юниверсити оф Токио Новый способ получения дифференцированных клеток
WO2011048350A1 (en) * 2009-10-19 2011-04-28 Tristem Trading (Cyprus) Limited Treatment using reprogrammed mature adult cells
US20110206647A1 (en) * 2010-02-25 2011-08-25 Abt Holding Company Modulation of Angiogenesis
WO2011106476A1 (en) * 2010-02-25 2011-09-01 Abt Holding Company Modulation of microglia activation
US8774488B2 (en) 2010-03-11 2014-07-08 Cellscape Corporation Method and device for identification of nucleated red blood cells from a maternal blood sample
CA3128483A1 (en) 2010-05-12 2011-11-17 Abt Holding Company Modulation of splenocytes in cell therapy
WO2011158125A2 (en) 2010-06-17 2011-12-22 Katholieke Universiteit Leuven Methods for differentiating cells into hepatic stellate cells and hepatic sinusoidal endothelial cells, cells produced by the methods, and methods for using the cells
EP2609191B1 (de) 2010-08-24 2017-11-22 Regents Of The University Of Minnesota Nichtstatische suspensionskultur aus zellverbänden
WO2013163296A1 (en) * 2012-04-24 2013-10-31 The Brigham And Women's Hospital, Inc. Generating pluripotent cells de novo
RU2497947C1 (ru) * 2012-08-15 2013-11-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Сибирский государственный медицинский университет" Министерства зравоохранения и социального развития Российской Федерации (ГБОУ ВПО СибГМУ Минздравсоцразвития России) Способ модификации моноцитов периферической крови для повышения их паракринной активности при аутологической трансплантации
SG10201914136UA (en) 2013-04-12 2020-03-30 Saverio Lafrancesca Improving organs for transplantation
SG10201914102UA (en) 2016-01-21 2020-03-30 Abt Holding Co Stem cells for wound healing
JP2017008049A (ja) * 2016-07-04 2017-01-12 トライステム・トレイディング・（キプロス）・リミテッドＴｒｉＳｔｅｍ Ｔｒａｄｉｎｇ （Ｃｙｐｒｕｓ） Ｌｉｍｉｔｅｄ 再プログラム化成熟成体細胞を用いる治療
US20220125852A1 (en) * 2020-10-27 2022-04-28 Therapeutic Solutions International, Inc. Protection and regeneration of neurological function by using stem cells

Family Cites Families (15)

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Publication number Priority date Publication date Assignee Title
US5004681B1 (en) * 1987-11-12 2000-04-11 Biocyte Corp Preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood
US5061620A (en) * 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell
US6194376B1 (en) * 1991-03-11 2001-02-27 Creative Biomolecules, Inc. Method for modulating inflammatory response comprising administering morphogen
US5199942A (en) * 1991-06-07 1993-04-06 Immunex Corporation Method for improving autologous transplantation
EP0667792A1 (de) * 1991-11-22 1995-08-23 The General Hospital Corporation Spezifische toleranz bei transplantation
WO1993025216A1 (en) * 1992-06-08 1993-12-23 Becton, Dickinson And Company Human primitive stem cells
DE4240635C2 (de) * 1992-12-03 1997-07-10 Lothar Prof Dr Kanz Vermehrung hämatopoetischer Vorläuferzellen ex vivo sowieZusammensetzungen hämatopoetischer Wachstumsfaktoren
US5654186A (en) * 1993-02-26 1997-08-05 The Picower Institute For Medical Research Blood-borne mesenchymal cells
US5843780A (en) * 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
GB9502022D0 (en) * 1995-02-02 1995-03-22 Abuljadayel Ilham M S A method for preparing lymphohaematopoietic progenitor cells
US5877299A (en) * 1995-06-16 1999-03-02 Stemcell Technologies Inc. Methods for preparing enriched human hematopoietic cell preparations
US5843633A (en) * 1996-04-26 1998-12-01 Amcell Corporation Characterization of a human hematopoietic progenitor cell antigen
US6227202B1 (en) * 1996-09-03 2001-05-08 Maulana Azad Medical College Method of organogenesis and tissue regeneration/repair using surgical techniques
US6468794B1 (en) * 1999-02-12 2002-10-22 Stemcells, Inc. Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations
TWI288779B (en) * 2002-03-28 2007-10-21 Blasticon Biotech Forschung Dedifferentiated, programmable stem cells of monocytic origin, and their production and use

Also Published As

Publication number Publication date
EP0807166B1 (de) 2008-05-21
JP2009148266A (ja) 2009-07-09
KR19980701949A (ko) 1998-06-25
RU2177996C2 (ru) 2002-01-10
CN1180374A (zh) 1998-04-29
DK0807166T3 (da) 2008-09-22
RU2215539C2 (ru) 2003-11-10
NZ300650A (en) 1999-04-29
CA2211147A1 (en) 1996-08-08
ATE396253T1 (de) 2008-06-15
SI0807166T1 (sl) 2008-12-31
CY2206B1 (en) 2002-11-08
US20110143431A1 (en) 2011-06-16
JPH10513053A (ja) 1998-12-15
CA2211147C (en) 2012-01-17
BR9606866A (pt) 1997-12-23
AU4545196A (en) 1996-08-21
AP9701031A0 (en) 1997-07-31
AP693A (en) 1998-11-11
MX9705919A (es) 1997-10-31
US6090625A (en) 2000-07-18
KR100630591B1 (ko) 2007-04-11
IL139244A (en) 2006-10-05
WO1996023870A1 (en) 1996-08-08
JP2012040011A (ja) 2012-03-01
EP0807166A1 (de) 1997-11-19
ZA96727B (en) 1996-08-16
CN1289660C (zh) 2006-12-13
GB9502022D0 (en) 1995-03-22
ES2308774T3 (es) 2008-12-01
JP2007259868A (ja) 2007-10-11
PT807166E (pt) 2008-08-27
US20020076812A1 (en) 2002-06-20
IL116994A (en) 2001-01-11
HK1017710A1 (en) 1999-11-26

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