DE69638054D1 - Pharmazeutischer trägerstoff mit verbesserter verpressbarkeit - Google Patents

Pharmazeutischer trägerstoff mit verbesserter verpressbarkeit

Info

Publication number
DE69638054D1
DE69638054D1 DE69638054T DE69638054T DE69638054D1 DE 69638054 D1 DE69638054 D1 DE 69638054D1 DE 69638054 T DE69638054 T DE 69638054T DE 69638054 T DE69638054 T DE 69638054T DE 69638054 D1 DE69638054 D1 DE 69638054D1
Authority
DE
Germany
Prior art keywords
silicon dioxide
microcrystalline cellulose
improved
excipient
compressability
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69638054T
Other languages
English (en)
Inventor
John N Staniforth
Bob E Sherwood
Edward A Hunter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
J Rettenmaier and Soehne GmbH and Co KG
Original Assignee
J Rettenmaier and Soehne GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23460251&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69638054(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by J Rettenmaier and Soehne GmbH and Co KG filed Critical J Rettenmaier and Soehne GmbH and Co KG
Priority claimed from PCT/US1996/000539 external-priority patent/WO1996022080A1/en
Application granted granted Critical
Publication of DE69638054D1 publication Critical patent/DE69638054D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/2036—Silicones; Polysiloxanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/724—Devices having flexible or movable element
    • Y10S977/727—Devices having flexible or movable element formed from biological material
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
    • Y10S977/775—Nanosized powder or flake, e.g. nanosized catalyst
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/788—Of specified organic or carbon-based composition
    • Y10S977/797—Lipid particle
    • Y10S977/798—Lipid particle having internalized material
    • Y10S977/799—Containing biological material
    • Y10S977/801—Drug
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/84—Manufacture, treatment, or detection of nanostructure
    • Y10S977/89—Deposition of materials, e.g. coating, cvd, or ald
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/84—Manufacture, treatment, or detection of nanostructure
    • Y10S977/895—Manufacture, treatment, or detection of nanostructure having step or means utilizing chemical property
    • Y10S977/896—Chemical synthesis, e.g. chemical bonding or breaking
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906—Drug delivery
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
DE69638054T 1995-01-09 1996-01-05 Pharmazeutischer trägerstoff mit verbesserter verpressbarkeit Expired - Lifetime DE69638054D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/370,576 US5585115A (en) 1995-01-09 1995-01-09 Pharmaceutical excipient having improved compressability
US08/486,183 US5725883A (en) 1995-01-09 1995-06-07 Pharmaceutical excipient having improved compressibility
PCT/US1996/000539 WO1996022080A1 (en) 1995-01-09 1996-01-05 Pharmaceutical excipient having improved compressibility

Publications (1)

Publication Number Publication Date
DE69638054D1 true DE69638054D1 (de) 2009-11-26

Family

ID=23460251

Family Applications (3)

Application Number Title Priority Date Filing Date
DE69638015T Expired - Lifetime DE69638015D1 (de) 1995-01-09 1996-01-05 Pharmazeutischer Trägerstoff mit verbesserter Verpressbarkeit
DE69627934T Expired - Lifetime DE69627934T2 (de) 1995-01-09 1996-01-05 Pharmazeutischer hilfsstoff mit verbesserter kompressibilität
DE69638054T Expired - Lifetime DE69638054D1 (de) 1995-01-09 1996-01-05 Pharmazeutischer trägerstoff mit verbesserter verpressbarkeit

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE69638015T Expired - Lifetime DE69638015D1 (de) 1995-01-09 1996-01-05 Pharmazeutischer Trägerstoff mit verbesserter Verpressbarkeit
DE69627934T Expired - Lifetime DE69627934T2 (de) 1995-01-09 1996-01-05 Pharmazeutischer hilfsstoff mit verbesserter kompressibilität

Country Status (19)

Country Link
US (10) US5585115A (de)
EP (2) EP0752848B1 (de)
JP (1) JP3300364B2 (de)
KR (1) KR100332337B1 (de)
AT (3) ATE239450T1 (de)
AU (1) AU698667B2 (de)
BR (1) BR9605329B1 (de)
CA (1) CA2183881C (de)
DE (3) DE69638015D1 (de)
DK (1) DK0752848T3 (de)
ES (1) ES2199281T3 (de)
FI (1) FI118754B (de)
HU (1) HUP9602360A3 (de)
IL (1) IL116675A (de)
MX (1) MX9603745A (de)
NO (1) NO320533B1 (de)
PT (1) PT752848E (de)
TW (1) TW372874B (de)
WO (1) WO1996021429A1 (de)

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AU4759896A (en) 1996-07-31
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DE69638015D1 (de) 2009-10-15
JPH10500426A (ja) 1998-01-13
HUP9602360A2 (en) 1997-08-28
JP3300364B2 (ja) 2002-07-08
EP1287823A1 (de) 2003-03-05
BR9605329A (pt) 1997-09-16
FI118754B (fi) 2008-03-14
CA2183881A1 (en) 1996-07-18
HUP9602360A3 (en) 2001-12-28
US20030096005A1 (en) 2003-05-22
EP0752848A4 (de) 1998-11-04
MX9603745A (es) 1997-07-31
IL116675A (en) 2000-10-31
NO963732D0 (no) 1996-09-06
IL116675A0 (en) 1996-05-14
ES2199281T3 (es) 2004-02-16
HU9602360D0 (en) 1996-11-28
WO1996021429A1 (en) 1996-07-18
DK0752848T3 (da) 2003-09-01
DE69627934D1 (de) 2003-06-12
EP0752848A1 (de) 1997-01-15
US5725884A (en) 1998-03-10
TW372874B (en) 1999-11-01
US6103219A (en) 2000-08-15
ATE239450T1 (de) 2003-05-15
MX9603746A (es) 1997-07-31
CA2183881C (en) 2000-08-01
US20090169621A1 (en) 2009-07-02
US5585115A (en) 1996-12-17
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NO963732L (no) 1996-11-08
US5725883A (en) 1998-03-10
US6217909B1 (en) 2001-04-17
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US6521261B2 (en) 2003-02-18
US20020142032A1 (en) 2002-10-03
AU698667B2 (en) 1998-11-05
US6358533B2 (en) 2002-03-19
US20050013861A1 (en) 2005-01-20
PT752848E (pt) 2003-08-29
FI963497A0 (fi) 1996-09-06
US20010001664A1 (en) 2001-05-24
ATE441403T1 (de) 2009-09-15
KR100332337B1 (ko) 2002-11-11
FI963497A (fi) 1996-11-06

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