DE69638369D1 - Die Unterhaut als ein Wachstumssubstrat für Zellen - Google Patents

Die Unterhaut als ein Wachstumssubstrat für Zellen

Info

Publication number
DE69638369D1
DE69638369D1 DE69638369T DE69638369T DE69638369D1 DE 69638369 D1 DE69638369 D1 DE 69638369D1 DE 69638369 T DE69638369 T DE 69638369T DE 69638369 T DE69638369 T DE 69638369T DE 69638369 D1 DE69638369 D1 DE 69638369D1
Authority
DE
Germany
Prior art keywords
cells
growth substrate
subcutaneous tissue
subcutaneous
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69638369T
Other languages
English (en)
Inventor
Stephen F Badylak
George Boder
Sherry Voytik
Robert J Demeter
John K Critser
Chi Liu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
METHODIST HEALTH GROUP Inc
Purdue Research Foundation
Original Assignee
METHODIST HEALTH GROUP Inc
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by METHODIST HEALTH GROUP Inc, Purdue Research Foundation filed Critical METHODIST HEALTH GROUP Inc
Application granted granted Critical
Publication of DE69638369D1 publication Critical patent/DE69638369D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0655Chondrocytes; Cartilage
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/34Internal compartments or partitions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02Membranes; Filters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068General culture methods using substrates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0676Pancreatic cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0679Cells of the gastro-intestinal tract
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/32Amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/38Vitamins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/90Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
    • C12N2533/92Amnion; Decellularised dermis or mucosa
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/915Method or apparatus for preparing biological material
DE69638369T 1995-02-10 1996-02-09 Die Unterhaut als ein Wachstumssubstrat für Zellen Expired - Lifetime DE69638369D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/386,452 US5695998A (en) 1995-02-10 1995-02-10 Submucosa as a growth substrate for islet cells

Publications (1)

Publication Number Publication Date
DE69638369D1 true DE69638369D1 (de) 2011-06-16

Family

ID=23525638

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69638369T Expired - Lifetime DE69638369D1 (de) 1995-02-10 1996-02-09 Die Unterhaut als ein Wachstumssubstrat für Zellen
DE69630206T Expired - Lifetime DE69630206D1 (de) 1995-02-10 1996-02-09 Die unterhaut als ein wachstumssubstrat für zellen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69630206T Expired - Lifetime DE69630206D1 (de) 1995-02-10 1996-02-09 Die unterhaut als ein wachstumssubstrat für zellen

Country Status (8)

Country Link
US (4) US5695998A (de)
EP (2) EP1449916B1 (de)
JP (2) JP4054059B2 (de)
AR (1) AR000921A1 (de)
AU (1) AU719160B2 (de)
CA (1) CA2212704A1 (de)
DE (2) DE69638369D1 (de)
WO (1) WO1996024661A1 (de)

Families Citing this family (244)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6334872B1 (en) 1994-02-18 2002-01-01 Organogenesis Inc. Method for treating diseased or damaged organs
US6551618B2 (en) 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
US6485723B1 (en) * 1995-02-10 2002-11-26 Purdue Research Foundation Enhanced submucosal tissue graft constructs
US20020095218A1 (en) 1996-03-12 2002-07-18 Carr Robert M. Tissue repair fabric
US6043092A (en) * 1996-03-18 2000-03-28 University Of Pittsburgh Cell culture media for mammalian cells
US6171344B1 (en) * 1996-08-16 2001-01-09 Children's Medical Center Corporation Bladder submucosa seeded with cells for tissue reconstruction
EP0925077B1 (de) * 1996-08-23 2003-10-15 Cook Biotech, Inc. Verfahren zur gewinnung einer gereignigten matrix auf kollagenbasis aus submukosa gewebe
US8716227B2 (en) * 1996-08-23 2014-05-06 Cook Biotech Incorporated Graft prosthesis, materials and methods
US6666892B2 (en) * 1996-08-23 2003-12-23 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
US20060025786A1 (en) * 1996-08-30 2006-02-02 Verigen Transplantation Service International (Vtsi) Ag Method for autologous transplantation
AU731768B2 (en) * 1996-09-16 2001-04-05 Purdue Research Foundation Composition and method for repairing neurological tissue
WO1998025635A1 (en) * 1996-12-10 1998-06-18 Purdue Research Foundation Submucosal tissue inhibition of neoplastic cell growth
EP0946872A1 (de) * 1996-12-10 1999-10-06 Purdue Research Foundation Magensubmukosagewebe als neues diagnostisches werkzeug
WO1998025964A1 (en) * 1996-12-10 1998-06-18 Purdue Research Foundation Submucosa extracts
US6696270B2 (en) 1996-12-10 2004-02-24 Purdue Research Foundation Gastric submucosal tissue as a novel diagnostic tool
EP1011699B1 (de) * 1997-09-11 2001-12-05 Purdue Research Foundation Durch galactosidase modifiziertes submucosales gewebe
US7070607B2 (en) 1998-01-27 2006-07-04 The Regents Of The University Of California Bioabsorbable polymeric implants and a method of using the same to create occlusions
US6444229B2 (en) 1998-02-27 2002-09-03 Purdue Research Foundation Submucosa gel compositions
AU772827B2 (en) * 1998-02-27 2004-05-06 Purdue Research Foundation, Of Office Of Technology Commercialization Purdue University Shape retaining gel compositions
JP4341050B2 (ja) * 1998-06-05 2009-10-07 オルガノジェネシス インク. 生体工学により作成した血管移植片補綴
JP4606583B2 (ja) * 1998-06-05 2011-01-05 オルガノジェネシス インク. 生物工学的手法による平面シート状移植補綴
CA2334228C (en) * 1998-06-05 2010-09-28 Organogenesis Inc. Bioengineered vascular graft support prostheses
JP4341049B2 (ja) * 1998-06-05 2009-10-07 オルガノジェネシス インク. 生物工学により作成したチューブ状移植片補綴
US6933326B1 (en) * 1998-06-19 2005-08-23 Lifecell Coporation Particulate acellular tissue matrix
EP1087756B1 (de) * 1998-06-19 2009-08-05 Lifecell Corporation Teilchenförmige zellfreie gewebematrix
US6458109B1 (en) 1998-08-07 2002-10-01 Hill-Rom Services, Inc. Wound treatment apparatus
CA2342589A1 (en) * 1998-09-11 2000-03-23 Purdue Research Foundation Enhanced submucosal tissue graft constructs
US6506599B1 (en) * 1999-10-15 2003-01-14 Tai-Wook Yoon Method for culturing langerhans islets and islet autotransplantation islet regeneration
ES2249928T3 (es) * 1998-11-19 2006-04-01 Organogenesis Inc. Constructos de tejido manipulado mediante bioingenieria y metodos para producirlos y utilizarlos.
US6918396B1 (en) 1998-12-01 2005-07-19 Purdue Research Foundation Method for vocal cord reconstruction
US8882850B2 (en) 1998-12-01 2014-11-11 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
WO2000032250A1 (en) 1998-12-01 2000-06-08 Cook Biotech, Inc. A multi-formed collagenous biomaterial medical device
US6365385B1 (en) 1999-03-22 2002-04-02 Duke University Methods of culturing and encapsulating pancreatic islet cells
US6303355B1 (en) 1999-03-22 2001-10-16 Duke University Method of culturing, cryopreserving and encapsulating pancreatic islet cells
US6521191B1 (en) * 1999-07-07 2003-02-18 Novosis Ag Permeation cell for in vitro determination of skin permeation of pharmaceutical drugs
DE29911790U1 (de) * 1999-07-07 1999-09-30 Novosis Pharma Ag Permeationszelle zur in-vitro-Bestimmung der Hautpermeation von pharmazeutischen Wirkstoffen
US20020116063A1 (en) * 1999-08-02 2002-08-22 Bruno Giannetti Kit for chondrocyte cell transplantation
EP1207819B1 (de) 1999-08-06 2009-03-04 Cook Biotech, Inc. Rohrförmige transplantatkonstruktion
US6824533B2 (en) 2000-11-29 2004-11-30 Hill-Rom Services, Inc. Wound treatment apparatus
US6764462B2 (en) 2000-11-29 2004-07-20 Hill-Rom Services Inc. Wound treatment apparatus
US20040043006A1 (en) * 2002-08-27 2004-03-04 Badylak Stephen F. Tissue regenerative composition
WO2001045765A1 (en) 1999-12-22 2001-06-28 Acell, Inc. Tissue regenerative composition
US6579538B1 (en) 1999-12-22 2003-06-17 Acell, Inc. Tissue regenerative compositions for cardiac applications, method of making, and method of use thereof
US6576265B1 (en) 1999-12-22 2003-06-10 Acell, Inc. Tissue regenerative composition, method of making, and method of use thereof
US6428802B1 (en) 1999-12-29 2002-08-06 Children's Medical Center Corp. Preparing artificial organs by forming polylayers of different cell populations on a substrate
US6368859B1 (en) 1999-12-29 2002-04-09 Children's Medical Center Corporation Methods and compositions for producing a fascial sling
US6376244B1 (en) * 1999-12-29 2002-04-23 Children's Medical Center Corporation Methods and compositions for organ decellularization
ATE407647T1 (de) 2000-05-22 2008-09-15 Arthur C Coffey Wundverband mit sis-schicht und vakuumkammer
DE10026482A1 (de) * 2000-05-29 2001-12-13 Augustinus Bader Verfahren zur Herstellung eines bioartifiziellen Transplantats
US20080182293A1 (en) * 2000-07-14 2008-07-31 Transform Pharmaceuticals, Inc. Computerized control of high-throughput transdermal experimental processing and digital analysis of comparative samples
US6852526B2 (en) * 2000-07-14 2005-02-08 Transform Pharmaceuticals, Inc. Transdermal assay with magnetic clamp
US7172859B2 (en) * 2000-07-14 2007-02-06 Transform Pharmaceuticals, Inc. System and method for optimizing tissue barrier transfer of compounds
IL153468A0 (en) * 2000-07-14 2003-07-06 Transform Pharmaceuticals Inc System and method for optimizing tissue barrier transfer of compounds
US6638312B2 (en) 2000-08-04 2003-10-28 Depuy Orthopaedics, Inc. Reinforced small intestinal submucosa (SIS)
US8366787B2 (en) 2000-08-04 2013-02-05 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
WO2002020825A1 (en) * 2000-09-09 2002-03-14 The Research Foundation Of State University Of New York Method and compositions for isolating metastatic cancer cells, and use in measuring metastatic potential of a cancer thereof
EP1320390A2 (de) * 2000-09-18 2003-06-25 Organogenesis Inc. Bioartifizielle flache schichtförmige prothesen und ihre verwendung
US6740501B2 (en) * 2000-09-27 2004-05-25 Becton, Dickinson And Company Coated membrane for assessing the invasive capacity of a cell
US6685681B2 (en) 2000-11-29 2004-02-03 Hill-Rom Services, Inc. Vacuum therapy and cleansing dressing for wounds
US6855135B2 (en) 2000-11-29 2005-02-15 Hill-Rom Services, Inc. Vacuum therapy and cleansing dressing for wounds
KR100915482B1 (ko) * 2000-12-06 2009-09-03 하리리 로버트 제이 태반 줄기 세포의 회수 방법
US20080152629A1 (en) * 2000-12-06 2008-06-26 James Edinger Placental stem cell populations
US20070122388A1 (en) 2000-12-08 2007-05-31 Kropp Bradley P Tissue graft compositions and methods for producing same
US7122200B2 (en) * 2000-12-08 2006-10-17 The Board Of Regents Of The University Of Oklahoma Vitro engineered, regenerated urinary tract tissue compositions and methods for producing same
EP1362095B1 (de) * 2001-02-14 2015-05-27 Anthrogenesis Corporation Post-partum säugetier-plazenta, deren verwendung und daraus gewonnene stammzellen
WO2002067867A2 (en) * 2001-02-23 2002-09-06 The University Of Pittsburgh Rapid preparation of stem cell matrices for use in tissue and organ treatment and repair
US6706520B2 (en) 2001-06-13 2004-03-16 Kehan Han Assessment of invasive potential of tumor cells
AU2002320189B2 (en) 2001-06-28 2007-04-26 Cook Biotech Incorporated Graft prosthesis devices containing renal capsule collagen
US7819918B2 (en) 2001-07-16 2010-10-26 Depuy Products, Inc. Implantable tissue repair device
JP4197157B2 (ja) 2001-07-16 2008-12-17 デピュイ・プロダクツ・インコーポレイテッド 軟骨修復再生装置および方法
WO2003007784A2 (en) 2001-07-16 2003-01-30 Depuy Products, Inc. Meniscus regeneration device and method
US7163563B2 (en) 2001-07-16 2007-01-16 Depuy Products, Inc. Unitary surgical device and method
US7201917B2 (en) 2001-07-16 2007-04-10 Depuy Products, Inc. Porous delivery scaffold and method
US8025896B2 (en) 2001-07-16 2011-09-27 Depuy Products, Inc. Porous extracellular matrix scaffold and method
WO2003007839A2 (en) 2001-07-16 2003-01-30 Depuy Products, Inc. Devices form naturally occurring biologically derived
WO2003007790A2 (en) 2001-07-16 2003-01-30 Depuy Products, Inc. Hybrid biologic/synthetic porous extracellular matrix scaffolds
US7361195B2 (en) 2001-07-16 2008-04-22 Depuy Products, Inc. Cartilage repair apparatus and method
US20110091353A1 (en) * 2001-09-24 2011-04-21 Wilson Burgess Methods for Sterilizing Tissue
CA2462877A1 (en) 2001-10-11 2003-04-17 Hill-Rom Services, Inc. Waste container for negative pressure therapy
US8592176B2 (en) * 2001-10-15 2013-11-26 Japan Science And Technology Corporation Methods for forming and using a stratified structure of epithelial cells
WO2003035125A2 (en) 2001-10-26 2003-05-01 Cook Biotech Incorporated Medical graft device with meshed structure
AU2002353078A1 (en) * 2001-12-07 2003-07-09 Earl Y. Cheng Tissue graft compositions and methods for producing same
WO2003057307A1 (en) 2001-12-26 2003-07-17 Hill-Rom Services, Inc. Wound vacuum therapy dressing kit
US7534927B2 (en) 2001-12-26 2009-05-19 Hill-Rom Services, Inc. Vacuum bandage packing
US7195624B2 (en) 2001-12-26 2007-03-27 Hill-Rom Services, Inc. Vented vacuum bandage with irrigation for wound healing and method
US8394371B2 (en) 2002-02-11 2013-03-12 Neocutis Sa Compositions for the treatment of skin conditions, disorders or diseases and methods of making and using the same
US20100254900A1 (en) * 2002-03-18 2010-10-07 Campbell Phil G Biocompatible polymers and Methods of use
US8529956B2 (en) 2002-03-18 2013-09-10 Carnell Therapeutics Corporation Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
AU2003215023A1 (en) * 2002-03-22 2003-10-13 Bayer Pharmaceuticals Corporation Method for producing pseudo islets
JP4431399B2 (ja) * 2002-03-25 2010-03-10 泰彦 田畑 脱細胞化組織マトリックス及び細胞成長因子を含む組織又は臓器再建用基材
US9144583B2 (en) 2002-03-29 2015-09-29 Tissue Genesis, Inc. Cell separation apparatus and methods of use
US8202725B2 (en) * 2004-12-23 2012-06-19 Tissue Genesis Incorporated Cell sodding method and apparatus
AU2002359824A1 (en) 2002-04-10 2003-10-27 Hill-Rom Services, Inc. Access openings in vacuum bandage
US20040166169A1 (en) * 2002-07-15 2004-08-26 Prasanna Malaviya Porous extracellular matrix scaffold and method
WO2004010852A2 (en) * 2002-07-31 2004-02-05 Kropp Bradley P Tissue compositions and methods for producing same
EP1545644B2 (de) 2002-08-21 2018-02-28 KCI Medical Resources Wundpackung zur vorbeugung des wundverschlusses
US7449307B2 (en) * 2002-10-28 2008-11-11 Transform Pharmaceuticals, Inc. Raised surface assay plate
EP1556501A4 (de) * 2002-10-28 2009-04-08 Transform Pharmaceuticals Inc Transdermaler assay mit magnetischerklemme
US6908760B2 (en) * 2002-10-28 2005-06-21 Transform Pharmaceuticals, Inc. Raised surface assay plate
EP1571910A4 (de) 2002-11-26 2009-10-28 Anthrogenesis Corp Zytotherapeutika, zytotherapeutischeeinheiten und behandlungsverfahren, bei denen diese verwendet werden
NZ542127A (en) * 2003-02-13 2008-04-30 Anthrogenesis Corp Use of umbilical cord blood to treat individuals having a disease, disorder or condition
US20040175366A1 (en) * 2003-03-07 2004-09-09 Acell, Inc. Scaffold for cell growth and differentiation
US20040176855A1 (en) * 2003-03-07 2004-09-09 Acell, Inc. Decellularized liver for repair of tissue and treatment of organ deficiency
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US7488348B2 (en) 2003-05-16 2009-02-10 Musculoskeletal Transplant Foundation Cartilage allograft plug
US20060228339A1 (en) * 2003-06-16 2006-10-12 Zheng-Pin Wang Methods of preparing transplantable product for treatment of skin defects
AU2004253508A1 (en) 2003-06-25 2005-01-13 Acell, Inc. Conditioned matrix compositions for tissue restoration
US20050054099A1 (en) * 2003-09-04 2005-03-10 Cedars Sinai Medical Center Matrix derived from whole organ
AU2004270239C1 (en) 2003-09-04 2011-07-07 Cook Biotech Incorporated Extracellular matrix composite materials, and manufacture and use thereof
GB0321337D0 (en) * 2003-09-11 2003-10-15 Massone Mobile Advertising Sys Method and system for distributing advertisements
KR20110116225A (ko) * 2003-12-02 2011-10-25 셀진 코포레이션 혈색소병증 및 빈혈의 치료 및 관리를 위한 방법및 조성물
ES2396689T3 (es) 2003-12-11 2013-02-25 Isto Technologies Inc. Sistema de cartílago particulado
WO2005077433A1 (en) * 2004-02-09 2005-08-25 Cook Biotech Incorporated Stent graft devices having collagen coating
NZ550027A (en) * 2004-03-26 2009-03-31 Celgene Corp Systems and methods for providing a stem cell bank
US7569233B2 (en) 2004-05-04 2009-08-04 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
US20050249772A1 (en) * 2004-05-04 2005-11-10 Prasanna Malaviya Hybrid biologic-synthetic bioabsorbable scaffolds
US20050288796A1 (en) * 2004-06-23 2005-12-29 Hani Awad Native soft tissue matrix for therapeutic applications
US8257715B1 (en) 2004-08-26 2012-09-04 University Of Notre Dame Tissue vaccines and uses thereof
US20060058238A1 (en) 2004-09-15 2006-03-16 Lee Laurent-Applegate Fetal skin cell protein compositions for the treatment of skin conditions, disorders or diseases and methods of making and using the same
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US7513866B2 (en) 2004-10-29 2009-04-07 Depuy Products, Inc. Intestine processing device and associated method
US7905826B2 (en) 2004-11-03 2011-03-15 Cook Incorporated Methods for modifying vascular vessel walls
US8329202B2 (en) * 2004-11-12 2012-12-11 Depuy Products, Inc. System and method for attaching soft tissue to an implant
WO2006062976A2 (en) 2004-12-07 2006-06-15 Cook Incorporated Methods for modifying vascular vessel walls
US7354627B2 (en) 2004-12-22 2008-04-08 Depuy Products, Inc. Method for organizing the assembly of collagen fibers and compositions formed therefrom
US20060206139A1 (en) * 2005-01-19 2006-09-14 Tekulve Kurt J Vascular occlusion device
US7851189B2 (en) * 2005-03-07 2010-12-14 Boston Scientific Scimed, Inc. Microencapsulated compositions for endoluminal tissue engineering
US8454678B2 (en) * 2005-03-19 2013-06-04 Cook Biotech Incorporated Prosthetic implants including ECM composite material
WO2007002260A2 (en) * 2005-06-21 2007-01-04 Cook Incorporated Implantable graft to close a fistula
US20060292227A1 (en) * 2005-06-23 2006-12-28 Mcpherson Timothy B Extracellular matrix material particles and methods of preparation
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
CA2615208A1 (en) * 2005-07-12 2007-01-18 Tissue Genesis, Inc. Apparatus and methods for preparing tissue grafts
US7595062B2 (en) 2005-07-28 2009-09-29 Depuy Products, Inc. Joint resurfacing orthopaedic implant and associated method
EP2093256A3 (de) 2005-07-28 2009-10-14 Carnegie Mellon University Biokompatible Polymere und Verwendungsverfahren
JP5292533B2 (ja) 2005-08-26 2013-09-18 ジンマー・インコーポレイテッド インプラントおよび関節疾患の治療、置換および治療方法
CA2623106C (en) 2005-09-19 2013-12-24 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
ES2452595T3 (es) 2005-10-13 2014-04-02 Anthrogenesis Corporation Inmunomodulación usando células madre de la placenta
US20070190165A1 (en) * 2005-10-21 2007-08-16 Brey Eric M Tissue-specific basement membrane gels
US8802113B2 (en) * 2005-10-27 2014-08-12 University Of Notre Dame Extracellular matrix cancer vaccine adjuvant
US9308252B2 (en) 2005-10-27 2016-04-12 Cook Biotech, Inc. Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins
US8778362B2 (en) * 2005-10-27 2014-07-15 University Of Notre Dame Anti-tumor/cancer heterologous acellular collagenous preparations and uses thereof
US8778360B2 (en) * 2005-10-27 2014-07-15 University Of Notre Dame Extracellular matrix cancer vaccine adjuvant
US8455250B2 (en) 2005-12-29 2013-06-04 Anthrogenesis Corporation Co-culture of placental stem cells and stem cells from a second source
PL2471904T3 (pl) * 2005-12-29 2019-08-30 Celularity, Inc. Populacje komórek macierzystych łożyska
US20070166396A1 (en) 2006-01-06 2007-07-19 University Of Pittsburgh Extracellular matrix based gastroesophageal junction reinforcement device
US8974542B2 (en) 2006-06-27 2015-03-10 University of Pittsburgh—of the Commonwealth System of Higher Education Biodegradable elastomeric patch for treating cardiac or cardiovascular conditions
US8535719B2 (en) * 2006-07-07 2013-09-17 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Biohybrid elastomeric scaffolds and methods of use thereof
US20080109070A1 (en) * 2006-08-10 2008-05-08 Wagner William R Biodegradable elastomeric scaffolds containing microintegrated cells
US8529959B2 (en) 2006-10-17 2013-09-10 Carmell Therapeutics Corporation Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
EP2079490B1 (de) 2006-10-23 2012-08-29 Cook Biotech Incorporated Aufbereitete ecm-materialien mit erweiterten komponentenprofilen
WO2008060973A1 (en) * 2006-11-10 2008-05-22 Vance Products Incorporated D/B/A Cook Urological Incorporated Graft for hysterotomy closure
US7871440B2 (en) 2006-12-11 2011-01-18 Depuy Products, Inc. Unitary surgical device and method
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
US8343536B2 (en) 2007-01-25 2013-01-01 Cook Biotech Incorporated Biofilm-inhibiting medical products
AU2008216749B2 (en) * 2007-02-12 2014-03-13 Celularity Inc. Treatment of inflammatory diseases using placental stem cells
EP2129775A1 (de) * 2007-02-12 2009-12-09 Anthrogenesis Corporation Hepatocyten und chondrocyten aus adhärenten plazentastammzellen sowie cd34+, cd45- plazentastammzellenangereicherte zellpopulationen
US8361503B2 (en) * 2007-03-02 2013-01-29 University of Pittsburgh—of the Commonwealth System of Higher Education Extracellular matrix-derived gels and related methods
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
US20100172830A1 (en) * 2007-03-29 2010-07-08 Cellx Inc. Extraembryonic Tissue cells and method of use thereof
WO2008128075A1 (en) 2007-04-12 2008-10-23 Isto Technologies, Inc. Compositions and methods for tissue repair
US20080279833A1 (en) * 2007-05-10 2008-11-13 Matheny Robert G Laminate sheet articles for tissue regeneration
WO2009004995A1 (ja) 2007-06-29 2009-01-08 Stelic Institute Of Regenerative Medicine, Stelic Institute & Co. 生理活性物質を定着および発現させる方法
US20090082816A1 (en) 2007-09-20 2009-03-26 Graham Matthew R Remodelable orthopaedic spacer and method of using the same
US20090136553A1 (en) * 2007-09-25 2009-05-28 Gerlach Jorg C Triggerably dissolvable hollow fibers for controlled delivery
KR20220122774A (ko) * 2007-09-26 2022-09-02 셀룰래리티 인코포레이티드 인간 태반 관류액으로부터의 혈관형성 세포
US20100135964A1 (en) * 2007-09-27 2010-06-03 Alvarado Carlos A Tissue grafting method
US9023342B2 (en) 2007-09-27 2015-05-05 Carlos A. Alvarado Tissue grafting method
EP2783692B1 (de) * 2007-09-28 2019-01-02 Celularity, Inc. Tumorsuppression mit menschlichem Plazentaperfusat und menschlichen natürlichen Killerzellen eines Zwischenproduktes aus der Plazenta
MX2010005018A (es) * 2007-11-07 2010-05-27 Anthrogenesis Corp Tratamiento de complicaciones de nacimiento prematuro.
US8257434B2 (en) 2007-12-18 2012-09-04 Cormatrix Cardiovascular, Inc. Prosthetic tissue valve
US8679176B2 (en) 2007-12-18 2014-03-25 Cormatrix Cardiovascular, Inc Prosthetic tissue valve
US9283266B2 (en) * 2008-02-28 2016-03-15 University Of Notre Dame Metastasis inhibition preparations and methods
WO2009111069A1 (en) 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US20110184439A1 (en) * 2008-05-09 2011-07-28 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Biological Matrix for Cardiac Repair
WO2010014021A1 (en) 2008-07-30 2010-02-04 Mesynthes Limited Tissue scaffolds derived from forestomach extracellular matrix
CN105796602A (zh) * 2008-08-20 2016-07-27 人类起源公司 利用分离的胎盘细胞治疗中风
MX2011001990A (es) * 2008-08-20 2011-03-29 Anthrogenesis Corp Composiciones mejoradas de celulas y metodos para preparar las mismas.
CN102176919A (zh) * 2008-08-22 2011-09-07 人类起源公司 用胎盘细胞群治疗骨缺损的方法和组合物
EP3184552B1 (de) 2008-09-02 2020-08-12 Tautona Group LP Stränge aus hyaluronsäure, verfahren zur herstellung davon und verwendungen davon
US20110190680A1 (en) 2008-09-29 2011-08-04 Yoram Vodovotz Self-Regulating Device for Modulating Inflammation
GB0817990D0 (en) * 2008-10-02 2008-11-05 Reinnervate Ltd Cell culture vessel
KR20110086176A (ko) * 2008-11-19 2011-07-27 안트로제네시스 코포레이션 양막 유래 부착성 세포
MX2011005230A (es) * 2008-11-21 2011-06-16 Anthrogenesis Corp Tratamiento de enfermedades, desordenes o condiciones del pulmon usando celulas de placenta.
WO2010065843A2 (en) 2008-12-05 2010-06-10 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Biologic scaffold for prevention of pulmonary fibrosis
IL196820A0 (en) * 2009-02-01 2009-11-18 Yissum Res Dev Co Devitalized, acellular scaffold matrices derived from micro-organs seeded with various cells
WO2010093882A1 (en) * 2009-02-13 2010-08-19 Wake Forest University Health Sciences Keratin biomaterials for cell culture and methods of use
WO2010096458A1 (en) 2009-02-18 2010-08-26 Cormatrix Cardiovascular, Inc. Compositions and methods for preventing cardiac arrhythmia
US9277999B2 (en) * 2009-02-27 2016-03-08 University of Pittsburgh—of the Commonwealth System of Higher Education Joint bioscaffolds
WO2010129162A1 (en) 2009-05-06 2010-11-11 Hansa Medical Products, Inc. Self-adjusting medical device
US8652500B2 (en) 2009-07-22 2014-02-18 Acell, Inc. Particulate tissue graft with components of differing density and methods of making and using the same
US8298586B2 (en) 2009-07-22 2012-10-30 Acell Inc Variable density tissue graft composition
CA2771261A1 (en) * 2009-08-17 2011-02-24 Ashok K. Singh Fluid associated with adult stem cells for medical, cosmetic, and veterinary use
US8716438B2 (en) 2009-10-09 2014-05-06 University of Pittsburgh—of the Commonwealth System of Higher Education Matricryptic ECM peptides for tissue reconstruction
US8846059B2 (en) 2009-12-08 2014-09-30 University Of Notre Dame Extracellular matrix adjuvant and methods for prevention and/or inhibition of ovarian tumors and ovarian cancer
US20110150934A1 (en) * 2009-12-18 2011-06-23 University Of Notre Dame Ovarian Tumor Tissue Cell Preparations/Vaccines for the Treatment/Inhibition of Ovarian Tumors and Ovarian Cancer
WO2011087743A2 (en) 2009-12-22 2011-07-21 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Decellularized adipose cell growth scaffold
ES2646750T3 (es) * 2010-01-26 2017-12-15 Anthrogenesis Corporation Tratamiento de cánceres relacionados con hueso utilizando células madre placentarias
SI2556145T1 (sl) 2010-04-07 2017-01-31 Anthrogenesis Corporation Angiogeneza z uporabo placentnih matičnih celic
KR20130092394A (ko) 2010-04-08 2013-08-20 안트로제네시스 코포레이션 태반 줄기 세포를 사용한 사르코이드증의 치료
US9901659B2 (en) 2010-05-27 2018-02-27 University of Pittsburgh—of the Commonwealth System of Higher Education Wet-electrospun biodegradable scaffold and uses therefor
US20130197893A1 (en) 2010-06-07 2013-08-01 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods for modeling hepatic inflammation
CN103491898B (zh) 2010-07-02 2015-11-25 北卡罗来纳-查佩尔山大学 用于工业规模分散的生物基质支架
NZ605505A (en) 2010-07-13 2015-02-27 Anthrogenesis Corp Methods of generating natural killer cells
WO2012024390A2 (en) 2010-08-17 2012-02-23 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Biohybrid composite scaffold
EP3610861A1 (de) 2010-08-24 2020-02-19 The Regents of the University of California Zusammensetzungen und verfahren für eine herztherapie
AR093183A1 (es) 2010-12-31 2015-05-27 Anthrogenesis Corp Aumento de la potencia de celulas madre de placenta usando moleculas de arn moduladoras
BR112013030567B1 (pt) * 2011-05-27 2021-02-17 DePuy Synthes Products, LLC dispositivos de túbulo proximal bioartificial e método in vitro para gerar um dispositivo de túbulo proximal bioartificial por diferenciação de uma ou mais células precursoras em células renais
SG194880A1 (en) 2011-05-27 2013-12-30 Cormatrix Cardiovascular Inc Sterilized, acellular extracellular matrix compositions and methods ofmaking thereof
EP3443968A1 (de) 2011-06-01 2019-02-20 Celularity, Inc. Schmerzbehandlung mithilfe von stammzellen aus der plazenta
US9925221B2 (en) 2011-09-09 2018-03-27 Celularity, Inc. Treatment of amyotrophic lateral sclerosis using placental stem cells
BR112014014975B1 (pt) 2011-12-20 2019-06-25 Lifecell Corporation Produto de tecido, e método para produzir uma composição de tecido
EP2793964B1 (de) 2011-12-20 2019-03-20 LifeCell Corporation Blattförmige tissueprodukte
US9271821B2 (en) 2012-01-24 2016-03-01 Lifecell Corporation Elongated tissue matrices
BR112014026088B1 (pt) 2012-04-24 2019-11-05 Lifecell Corp produto de tratamento de tecidos
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
AU2014215458A1 (en) 2013-02-05 2015-08-13 Anthrogenesis Corporation Natural killer cells from placenta
US9861662B2 (en) 2013-07-03 2018-01-09 University of Pittsburgh—of the Commonwealth System of Higher Education Bone-derived extra cellular matrix gel
US9878071B2 (en) 2013-10-16 2018-01-30 Purdue Research Foundation Collagen compositions and methods of use
US10286119B2 (en) 2014-01-24 2019-05-14 University of Pittsburgh—of the Commonwealth System of Higher Education Extracellular matrix mesh coating
JP6681872B2 (ja) 2014-03-21 2020-04-15 ユニバーシティ オブ ピッツバーグ −オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 細胞外マトリクス由来最終滅菌ヒドロゲルの調製方法
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
US10583004B2 (en) 2015-02-27 2020-03-10 University of Pittsburgh — Of the Commonwealth System of Higher Education Retrievable self-expanding non-thrombogenic low-profile percutaneous atrioventricular valve prosthesis
US11129711B2 (en) 2015-02-27 2021-09-28 University of Pittsburgh—of the Commonwealth System of Higher Education Double component mandrel for electrospun stentless, multi-leaflet valve fabrication
WO2016172365A1 (en) 2015-04-21 2016-10-27 Purdue Research Foundation Office Of Technology Commercialization Cell-collagen-silica composites and methods of making and using the same
US10736991B2 (en) 2015-09-18 2020-08-11 University of Pittsburgh—of the Commonwealth System of Higher Education Non-gelling soluble extracellular matrix with biological activity
US10173027B2 (en) 2015-10-07 2019-01-08 Cook Medical Technologies Llc Methods, medical devices and kits for modifying the luminal profile of a body vessel
WO2017151862A1 (en) 2016-03-02 2017-09-08 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Matrix bound nanovesicles and their use
US11331348B2 (en) 2016-04-28 2022-05-17 University of Pittsburgh—of the Commonwealth System of Higher Education Compositions comprising extracellular matrix of primitive animal species and related methods
EP3585313A4 (de) 2017-02-23 2020-12-30 University of Pittsburgh - of The Commonwealth System of Higher Education Zur lebendgeweberegeneration fähige, stentlose biopolymerherzklappe
EP4252842A3 (de) 2017-03-02 2023-10-25 University of Pittsburgh- Of the Commonwealth System of Higher Education Ecm-hydrogel zur behandlung von ösophagealer entzündung
EP3589294B1 (de) 2017-03-02 2022-10-26 University of Pittsburgh - Of the Commonwealth System of Higher Education Hydrogel aus extrazellulärer matrix (ecm) und lösliche fraktion davon zur verwendung in der behandlung von krebs
US10767164B2 (en) 2017-03-30 2020-09-08 The Research Foundation For The State University Of New York Microenvironments for self-assembly of islet organoids from stem cells differentiation
US11389569B2 (en) 2017-04-03 2022-07-19 University of Pittsburgh—of the Commonwealth System of Higher Education Biodegradable, porous, thermally responsive injectable hydrogel as soft tissue defect filler
EP3615568A4 (de) 2017-04-25 2021-01-20 Purdue Research Foundation Dreidimensionaler (3d) gewebegezüchteter muskel zur geweberestauration
KR20190141775A (ko) 2017-05-05 2019-12-24 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 기질 결합 소낭의 안구에의 적용
WO2019079195A1 (en) 2017-10-16 2019-04-25 University Of Pittsburgh - Of The Commonwealth System Of Higher Education GENETICALLY MODIFIED MESENCHYMAL STEM CELLS FOR USE IN CARDIOVASCULAR PROSTHESES
JP2022513073A (ja) 2018-11-19 2022-02-07 ザ ユナイテッド ステイツ オブ アメリカ アズ リプリゼンテッド バイ ザ セクレタリー、デパートメント オブ ヘルス アンド ヒューマン サービシーズ 生分解性組織置換インプラントおよびその使用
CA3130684A1 (en) 2019-03-13 2020-09-17 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Acoustic extracellular matrix hydrogels and their use
GB201916135D0 (en) 2019-11-06 2019-12-18 Ucl Business Plc Extracellular matrix gels, and organoid cultures comprising the same
US11826490B1 (en) 2020-12-29 2023-11-28 Acell, Inc. Extracellular matrix sheet devices with improved mechanical properties and method of making
CA3220433A1 (en) 2021-05-28 2022-12-01 Arvydas Maminishkis Biodegradable tissue scaffold with secondary matrix to host weakly adherent cells
EP4347795A1 (de) 2021-05-28 2024-04-10 The United States of America, as represented by The Secretary, Department of Health and Human Services Verfahren zur erzeugung von makula-, zentralen und peripheren retinapigmentepithelzellen
WO2023218789A1 (ja) * 2022-05-09 2023-11-16 凸版印刷株式会社 動物組織から幹細胞を回収する方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4439521A (en) * 1981-10-21 1984-03-27 Ontario Cancer Institute Method for producing self-reproducing mammalian pancreatic islet-like structures
US5352483A (en) * 1983-03-24 1994-10-04 Viscosuisse S.A. Preadhered melt spun spin-drawn polyester filaments
US4801299A (en) * 1983-06-10 1989-01-31 University Patents, Inc. Body implants of extracellular matrix and means and methods of making and using such implants
CA1295796C (en) * 1984-03-27 1992-02-18 Conrad Whyne Biodegradable matrix and methods for producing same
US4743552A (en) * 1984-09-26 1988-05-10 Sloan-Kettering Institute For Cancer Research Method for growth in tissue culture of normal colonic epithelial cells and method for determination of preneoplastic color cells
US4829000A (en) * 1985-08-30 1989-05-09 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Reconstituted basement membrane complex with biological activity
US5266480A (en) * 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
GB8618374D0 (en) * 1986-07-28 1986-09-03 Hsc Res Dev Corp Biological vascular prostheses
US5604106A (en) * 1987-06-05 1997-02-18 Us Commerce Method for detecting carcinoma
JPH0814679B2 (ja) * 1987-11-16 1996-02-14 富士写真光機株式会社 沈胴式ズームレンズ付カメラ
US4956178A (en) * 1988-07-11 1990-09-11 Purdue Research Foundation Tissue graft composition
US4902508A (en) * 1988-07-11 1990-02-20 Purdue Research Foundation Tissue graft composition
US4912057A (en) * 1989-06-13 1990-03-27 Cancer Diagnostics, Inc. Cell chamber for chemotaxis assay
US5275828A (en) * 1989-11-08 1994-01-04 Hooper Oswald E Treatment and/or a method of treating equine viral and bacterial infections
US5336616A (en) * 1990-09-12 1994-08-09 Lifecell Corporation Method for processing and preserving collagen-based tissues for transplantation
NZ239893A (en) * 1990-09-25 1993-11-25 Hoechst Japan A method for introducing a foreign dna into a cell
WO1992015676A1 (en) * 1991-03-08 1992-09-17 The Salk Institute For Biological Studies Somatic cell gene therapy
ATE215605T1 (de) * 1991-06-24 2002-04-15 Pacific Biomedical Res Inc In langzeitkultur gehaltene hormon-absondernde pankreatische zellen
US5281422A (en) * 1991-09-24 1994-01-25 Purdue Research Foundation Graft for promoting autogenous tissue growth
US5478739A (en) * 1992-10-23 1995-12-26 Advanced Tissue Sciences, Inc. Three-dimensional stromal cell and tissue culture system
US5275826A (en) * 1992-11-13 1994-01-04 Purdue Research Foundation Fluidized intestinal submucosa and its use as an injectable tissue graft
US5352463A (en) * 1992-11-13 1994-10-04 Badylak Steven F Tissue graft for surgical reconstruction of a collagenous meniscus and method therefor

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US6087157A (en) 2000-07-11
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