DE69718037D1 - Penetrationsfördernde substanzen für die transdermale verabreichung von wirkstoffen, vorrichtungen und verfahren zur herstellung - Google Patents
Penetrationsfördernde substanzen für die transdermale verabreichung von wirkstoffen, vorrichtungen und verfahren zur herstellungInfo
- Publication number
- DE69718037D1 DE69718037D1 DE69718037T DE69718037T DE69718037D1 DE 69718037 D1 DE69718037 D1 DE 69718037D1 DE 69718037 T DE69718037 T DE 69718037T DE 69718037 T DE69718037 T DE 69718037T DE 69718037 D1 DE69718037 D1 DE 69718037D1
- Authority
- DE
- Germany
- Prior art keywords
- drug
- transdermal administration
- permeation enhancer
- methods
- substances
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3042496P | 1996-10-24 | 1996-10-24 | |
| PCT/US1997/018956 WO1998017315A2 (en) | 1996-10-24 | 1997-10-23 | Permeation enhancers for transdermal drug delivery compositions, devices, and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69718037D1 true DE69718037D1 (de) | 2003-01-30 |
| DE69718037T2 DE69718037T2 (de) | 2003-07-10 |
Family
ID=21854141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69718037T Expired - Fee Related DE69718037T2 (de) | 1996-10-24 | 1997-10-23 | Penetrationsfördernde substanzen für die transdermale verabreichung von wirkstoffen, vorrichtungen und verfahren zur herstellung |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6004578A (de) |
| EP (1) | EP0934078B1 (de) |
| JP (1) | JP2001502693A (de) |
| AT (1) | ATE229817T1 (de) |
| AU (1) | AU4990797A (de) |
| CA (1) | CA2264687C (de) |
| DE (1) | DE69718037T2 (de) |
| DK (1) | DK0934078T3 (de) |
| ES (1) | ES2191834T3 (de) |
| WO (1) | WO1998017315A2 (de) |
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-
1997
- 1997-10-23 EP EP97912815A patent/EP0934078B1/de not_active Expired - Lifetime
- 1997-10-23 ES ES97912815T patent/ES2191834T3/es not_active Expired - Lifetime
- 1997-10-23 AU AU49907/97A patent/AU4990797A/en not_active Abandoned
- 1997-10-23 CA CA002264687A patent/CA2264687C/en not_active Expired - Fee Related
- 1997-10-23 WO PCT/US1997/018956 patent/WO1998017315A2/en active IP Right Grant
- 1997-10-23 AT AT97912815T patent/ATE229817T1/de not_active IP Right Cessation
- 1997-10-23 US US08/956,379 patent/US6004578A/en not_active Expired - Lifetime
- 1997-10-23 DK DK97912815T patent/DK0934078T3/da active
- 1997-10-23 DE DE69718037T patent/DE69718037T2/de not_active Expired - Fee Related
- 1997-10-23 JP JP10519563A patent/JP2001502693A/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US6004578A (en) | 1999-12-21 |
| WO1998017315A3 (en) | 1998-07-02 |
| EP0934078A2 (de) | 1999-08-11 |
| DE69718037T2 (de) | 2003-07-10 |
| DK0934078T3 (da) | 2003-04-14 |
| CA2264687C (en) | 2006-04-25 |
| JP2001502693A (ja) | 2001-02-27 |
| CA2264687A1 (en) | 1998-04-30 |
| EP0934078B1 (de) | 2002-12-18 |
| ES2191834T3 (es) | 2003-09-16 |
| ATE229817T1 (de) | 2003-01-15 |
| AU4990797A (en) | 1998-05-15 |
| WO1998017315A2 (en) | 1998-04-30 |
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| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |