DE69719992D1 - Verfahren zur verhinderung von verkalkung von glutaraldehyd fixierten implantaten und artikeln die nach dem verfahren hergestellt sind - Google Patents
Verfahren zur verhinderung von verkalkung von glutaraldehyd fixierten implantaten und artikeln die nach dem verfahren hergestellt sindInfo
- Publication number
- DE69719992D1 DE69719992D1 DE69719992T DE69719992T DE69719992D1 DE 69719992 D1 DE69719992 D1 DE 69719992D1 DE 69719992 T DE69719992 T DE 69719992T DE 69719992 T DE69719992 T DE 69719992T DE 69719992 D1 DE69719992 D1 DE 69719992D1
- Authority
- DE
- Germany
- Prior art keywords
- glutaraldehyde
- carboxyl
- exposed
- groups
- collagenous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/02—Treatment of implants to prevent calcification or mineralisation in vivo
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/915—Method or apparatus for preparing biological material
- Y10S623/916—Blood vessel
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/915—Method or apparatus for preparing biological material
- Y10S623/918—Heart
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/92—Method or apparatus for preparing or treating prosthetic
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/92—Method or apparatus for preparing or treating prosthetic
- Y10S623/921—Blood vessel
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/688,352 US5782931A (en) | 1996-07-30 | 1996-07-30 | Methods for mitigating calcification and improving durability in glutaraldehyde-fixed bioprostheses and articles manufactured by such methods |
PCT/US1997/010712 WO1998004299A1 (en) | 1996-07-30 | 1997-06-19 | Methods for mitigating calcification and improving durability in glutaraldehyde-fixed bioprostheses and articles manufactured by such methods |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69719992D1 true DE69719992D1 (de) | 2003-04-24 |
DE69719992T2 DE69719992T2 (de) | 2003-12-11 |
Family
ID=24764084
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69719992T Expired - Lifetime DE69719992T2 (de) | 1996-07-30 | 1997-06-19 | Verfahren zur verhinderung von verkalkung von glutaraldehyd fixierten implantaten und artikeln die nach dem verfahren hergestellt sind |
Country Status (7)
Country | Link |
---|---|
US (2) | US5782931A (de) |
EP (1) | EP0915714B1 (de) |
JP (1) | JP2000516489A (de) |
AT (1) | ATE234645T1 (de) |
CA (1) | CA2261811C (de) |
DE (1) | DE69719992T2 (de) |
WO (1) | WO1998004299A1 (de) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996004028A1 (en) * | 1994-07-29 | 1996-02-15 | Baxter International Inc. | Methods for treating implantable biological tissues to mitigate the calcification thereof and bioprosthetic articles treated by such methods |
IT1285308B1 (it) * | 1996-03-12 | 1998-06-03 | Sorin Biomedica Cardio Spa | Procedimento per la preparazione di materiale biologico per impianto |
IL118149A0 (en) * | 1996-05-05 | 1996-09-12 | Rdc Rafael Dev Corp | Method for producing heart valves and heart valves produced by the method |
US6214054B1 (en) | 1998-09-21 | 2001-04-10 | Edwards Lifesciences Corporation | Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby |
DE69922228T2 (de) | 1998-09-30 | 2005-12-01 | Medtronic, Inc., Minneapolis | Verfahren zur Reduzierung der Mineralisierung von Gewebe zum Gebrauch bei Transplantationen |
WO2000064371A1 (en) | 1999-04-27 | 2000-11-02 | The Children's Hospital Of Philadelphia | Stabilization of implantable bioprosthetic devices |
US6471723B1 (en) * | 2000-01-10 | 2002-10-29 | St. Jude Medical, Inc. | Biocompatible prosthetic tissue |
AUPR217300A0 (en) * | 2000-12-20 | 2001-01-25 | Ketharanathan, Vettivetpillai | Method of creating biological and biosynthetic material for implantation |
US20020177223A1 (en) * | 2001-03-12 | 2002-11-28 | Ogle Mathew F. | Methods and compositions for crosslinking tissue |
US7078163B2 (en) * | 2001-03-30 | 2006-07-18 | Medtronic, Inc. | Process for reducing mineralization of tissue used in transplantation |
US6878168B2 (en) | 2002-01-03 | 2005-04-12 | Edwards Lifesciences Corporation | Treatment of bioprosthetic tissues to mitigate post implantation calcification |
DE602004021022D1 (de) * | 2003-10-28 | 2009-06-18 | Medtronic Inc | Verfahren zur herstellung von vernetzten materialien und bioprothetischen vorrichtungen |
US7955788B2 (en) * | 2003-10-30 | 2011-06-07 | Medtronic, Inc. | Bioprosthetic tissue preparation with synthetic hydrogels |
US20050266390A1 (en) * | 2004-06-01 | 2005-12-01 | Yuichiro Ueda | Processes for removing cells and cell debris from tissue and tissue constructs used in transplantation and tissue reconstruction |
EP1819304B1 (de) | 2004-12-09 | 2023-01-25 | Twelve, Inc. | Aortaklappenreparatur |
JP5002805B2 (ja) | 2005-10-14 | 2012-08-15 | 財団法人ヒューマンサイエンス振興財団 | 生物由来スキャフォールドの作製方法 |
CN101626682B (zh) | 2006-10-27 | 2014-04-16 | 爱德华兹生命科学公司 | 用于外科植入的生物组织 |
US9101691B2 (en) * | 2007-06-11 | 2015-08-11 | Edwards Lifesciences Corporation | Methods for pre-stressing and capping bioprosthetic tissue |
US8357387B2 (en) | 2007-12-21 | 2013-01-22 | Edwards Lifesciences Corporation | Capping bioprosthetic tissue to reduce calcification |
US8986253B2 (en) | 2008-01-25 | 2015-03-24 | Tandem Diabetes Care, Inc. | Two chamber pumps and related methods |
US8408421B2 (en) | 2008-09-16 | 2013-04-02 | Tandem Diabetes Care, Inc. | Flow regulating stopcocks and related methods |
US8650937B2 (en) | 2008-09-19 | 2014-02-18 | Tandem Diabetes Care, Inc. | Solute concentration measurement device and related methods |
CA2769030C (en) | 2009-07-30 | 2016-05-10 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
FR2951549B1 (fr) | 2009-10-15 | 2013-08-23 | Olivier Schussler | Procede d'obtention de bioprotheses medicales implantables |
US9211361B2 (en) * | 2010-03-15 | 2015-12-15 | Kemal Schankereli | Thin collagen tissue for medical device applications |
CN102811681B (zh) | 2010-03-23 | 2016-10-12 | 爱德华兹生命科学公司 | 调节片状生物假体组织的方法 |
EP2569004A4 (de) * | 2010-05-10 | 2016-01-20 | Univ Connecticut | Biomaterialien auf lactoferrinbasis für geweberegeneration und wirkstofffreisetzung |
US8906601B2 (en) | 2010-06-17 | 2014-12-09 | Edwardss Lifesciences Corporation | Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates |
CN101947147A (zh) * | 2010-06-23 | 2011-01-19 | 乐普(北京)医疗器械股份有限公司 | 一种生物组织材料的化学处理方法 |
US9351829B2 (en) * | 2010-11-17 | 2016-05-31 | Edwards Lifesciences Corporation | Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability |
JP6010545B2 (ja) | 2010-12-23 | 2016-10-19 | トゥエルヴ, インコーポレイテッド | 僧帽弁の修復および置換のためのシステム |
CN107647939A (zh) | 2011-06-21 | 2018-02-02 | 托尔福公司 | 人工心脏瓣膜装置及相关系统 |
US9655722B2 (en) | 2011-10-19 | 2017-05-23 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
JP6151705B2 (ja) | 2011-10-19 | 2017-06-21 | トゥエルヴ, インコーポレイテッド | 心臓弁置換のためのデバイス、システムおよび方法 |
US9039757B2 (en) | 2011-10-19 | 2015-05-26 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US9763780B2 (en) | 2011-10-19 | 2017-09-19 | Twelve, Inc. | Devices, systems and methods for heart valve replacement |
JP6133309B2 (ja) | 2011-10-19 | 2017-05-24 | トゥエルヴ, インコーポレイテッド | 人工心臓弁デバイス |
US11202704B2 (en) | 2011-10-19 | 2021-12-21 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US9579198B2 (en) | 2012-03-01 | 2017-02-28 | Twelve, Inc. | Hydraulic delivery systems for prosthetic heart valve devices and associated methods |
US9180242B2 (en) | 2012-05-17 | 2015-11-10 | Tandem Diabetes Care, Inc. | Methods and devices for multiple fluid transfer |
US10238771B2 (en) | 2012-11-08 | 2019-03-26 | Edwards Lifesciences Corporation | Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system |
US9173998B2 (en) | 2013-03-14 | 2015-11-03 | Tandem Diabetes Care, Inc. | System and method for detecting occlusions in an infusion pump |
US10111747B2 (en) | 2013-05-20 | 2018-10-30 | Twelve, Inc. | Implantable heart valve devices, mitral valve repair devices and associated systems and methods |
US9615922B2 (en) | 2013-09-30 | 2017-04-11 | Edwards Lifesciences Corporation | Method and apparatus for preparing a contoured biological tissue |
US10959839B2 (en) | 2013-10-08 | 2021-03-30 | Edwards Lifesciences Corporation | Method for directing cellular migration patterns on a biological tissue |
US10238490B2 (en) | 2015-08-21 | 2019-03-26 | Twelve, Inc. | Implant heart valve devices, mitral valve repair devices and associated systems and methods |
CN109069272A (zh) | 2016-04-29 | 2018-12-21 | 美敦力瓦斯科尔勒公司 | 具有带系绳的锚定件的假体心脏瓣膜设备以及相关联的系统和方法 |
US10575950B2 (en) | 2017-04-18 | 2020-03-03 | Twelve, Inc. | Hydraulic systems for delivering prosthetic heart valve devices and associated methods |
US10702378B2 (en) | 2017-04-18 | 2020-07-07 | Twelve, Inc. | Prosthetic heart valve device and associated systems and methods |
US10433961B2 (en) | 2017-04-18 | 2019-10-08 | Twelve, Inc. | Delivery systems with tethers for prosthetic heart valve devices and associated methods |
US10792151B2 (en) | 2017-05-11 | 2020-10-06 | Twelve, Inc. | Delivery systems for delivering prosthetic heart valve devices and associated methods |
US10646338B2 (en) | 2017-06-02 | 2020-05-12 | Twelve, Inc. | Delivery systems with telescoping capsules for deploying prosthetic heart valve devices and associated methods |
US10709591B2 (en) | 2017-06-06 | 2020-07-14 | Twelve, Inc. | Crimping device and method for loading stents and prosthetic heart valves |
US10729541B2 (en) | 2017-07-06 | 2020-08-04 | Twelve, Inc. | Prosthetic heart valve devices and associated systems and methods |
US10786352B2 (en) | 2017-07-06 | 2020-09-29 | Twelve, Inc. | Prosthetic heart valve devices and associated systems and methods |
CN109260517B (zh) * | 2018-09-19 | 2020-10-30 | 杭州启明医疗器械股份有限公司 | 一种可预装干燥生物心脏瓣膜及其制备方法 |
CN109172867B (zh) * | 2018-09-19 | 2020-12-01 | 杭州启明医疗器械股份有限公司 | 一种可快速复水的预装式生物心脏瓣膜及其制备方法 |
US11517428B2 (en) | 2018-11-01 | 2022-12-06 | Edwards Lifesciences Corporation | Transcatheter pulmonic regenerative valve |
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-
1996
- 1996-07-30 US US08/688,352 patent/US5782931A/en not_active Expired - Lifetime
-
1997
- 1997-06-19 JP JP10508794A patent/JP2000516489A/ja not_active Ceased
- 1997-06-19 CA CA002261811A patent/CA2261811C/en not_active Expired - Lifetime
- 1997-06-19 DE DE69719992T patent/DE69719992T2/de not_active Expired - Lifetime
- 1997-06-19 EP EP97931288A patent/EP0915714B1/de not_active Expired - Lifetime
- 1997-06-19 AT AT97931288T patent/ATE234645T1/de not_active IP Right Cessation
- 1997-06-19 WO PCT/US1997/010712 patent/WO1998004299A1/en active IP Right Grant
-
1998
- 1998-03-20 US US09/044,667 patent/US5935168A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2000516489A (ja) | 2000-12-12 |
CA2261811C (en) | 2004-05-11 |
DE69719992T2 (de) | 2003-12-11 |
WO1998004299A1 (en) | 1998-02-05 |
ATE234645T1 (de) | 2003-04-15 |
CA2261811A1 (en) | 1998-02-05 |
US5935168A (en) | 1999-08-10 |
EP0915714A1 (de) | 1999-05-19 |
EP0915714B1 (de) | 2003-03-19 |
US5782931A (en) | 1998-07-21 |
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