DE69731834D1 - Agouti verwandtes gen - Google Patents

Agouti verwandtes gen

Info

Publication number
DE69731834D1
DE69731834D1 DE69731834T DE69731834T DE69731834D1 DE 69731834 D1 DE69731834 D1 DE 69731834D1 DE 69731834 T DE69731834 T DE 69731834T DE 69731834 T DE69731834 T DE 69731834T DE 69731834 D1 DE69731834 D1 DE 69731834D1
Authority
DE
Germany
Prior art keywords
art
gen
disclosed
agouti related
adrenal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69731834T
Other languages
English (en)
Other versions
DE69731834T2 (de
Inventor
Kevin Lee Stark
Roland Luethy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of DE69731834D1 publication Critical patent/DE69731834D1/de
Application granted granted Critical
Publication of DE69731834T2 publication Critical patent/DE69731834T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE69731834T 1996-05-10 1997-04-22 Agouti verwandtes gen Expired - Fee Related DE69731834T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US1750596P 1996-05-10 1996-05-10
US17505P 1996-05-10
US08/757,541 US5766877A (en) 1996-05-10 1996-11-27 Genes encoding art, an agouti-related transcript
US757541 1996-11-27
PCT/US1997/006853 WO1997043412A1 (en) 1996-05-10 1997-04-22 Novel agouti-related gene

Publications (2)

Publication Number Publication Date
DE69731834D1 true DE69731834D1 (de) 2005-01-05
DE69731834T2 DE69731834T2 (de) 2005-12-15

Family

ID=26689965

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69731834T Expired - Fee Related DE69731834T2 (de) 1996-05-10 1997-04-22 Agouti verwandtes gen

Country Status (12)

Country Link
US (5) US5766877A (de)
EP (1) EP0917571B1 (de)
JP (1) JP4219404B2 (de)
AT (1) ATE283917T1 (de)
AU (1) AU2681497A (de)
CA (1) CA2253238C (de)
DE (1) DE69731834T2 (de)
DK (1) DK0917571T3 (de)
ES (1) ES2234015T3 (de)
PT (1) PT917571E (de)
SI (1) SI0917571T1 (de)
WO (1) WO1997043412A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6310034B1 (en) 1993-05-21 2001-10-30 Ut-Battelle, Llc Agouti polypeptide compositions
US5843652A (en) * 1993-05-21 1998-12-01 Lockheed Martin Energy Systems, Inc. Isolation and characterization of Agouti: a diabetes/obesity related gene
WO2002064091A2 (en) * 2001-02-13 2002-08-22 Palatin Technologies, Inc. Melanocortin metallopeptides for treatment of sexual dysfunction
US5766877A (en) * 1996-05-10 1998-06-16 Amgen Inc. Genes encoding art, an agouti-related transcript
EP0942967A1 (de) * 1996-11-06 1999-09-22 Children's Medical Center Corporation Transgene-tier, das einen syndecan in den gebieten des hypothalamus exprimiert
JP2002508194A (ja) * 1997-12-16 2002-03-19 メルク エンド カムパニー インコーポレーテッド アグーチ関連転写産物（ａｒｔ）タンパク質のｃ末端領域
US6878520B1 (en) * 1997-12-16 2005-04-12 Merck & Co., Inc. C-terminal region of agouti-related transcript (ART) protein
WO1999050295A2 (en) * 1998-03-30 1999-10-07 Gryphon Sciences Agouti-related protein analogs and methods of use
US6689873B1 (en) 1998-04-29 2004-02-10 Merck & Co., Inc. Nucleic acid encoding rat agouti related protein
AU6022799A (en) * 1998-09-03 2000-03-27 Millennium Pharmaceuticals, Inc. Mc4-r as target for the identification of compounds used to treat drug addiction
US6603058B1 (en) 1998-12-09 2003-08-05 Oklahoma Medical Research Foundation Non-human animal model for obesity and uses thereof
US6716810B1 (en) * 1998-12-09 2004-04-06 Eleanor Roosevelt Institute Composition and method for regulation of body weight and associated conditions
US6303749B1 (en) * 1999-01-29 2001-10-16 Amgen Inc. Agouti and agouti-related peptide analogs
US20030064921A1 (en) * 1999-10-27 2003-04-03 The Regents Of The University Of California Methods and compounds for modulating melanocortin receptor ligand binding and activity
EP1125579A3 (de) 2000-01-18 2003-01-02 Pfizer Products Inc. Verwendungen von AGRP-Melanocortinrezeptorbindung modulierenden Verbindungen
US20020028897A1 (en) * 2000-05-31 2002-03-07 Johnson Lynda Kaye Copolymers of ethylene and selected acrylate esters
DE60216747T2 (de) 2001-04-09 2007-10-04 Novartis Vaccines and Diagnostics, Inc., Emeryville Guanidinoverbindungen als melanocortin-4-rezeptor (mc4-r) agonisten
US20030207814A1 (en) * 2002-02-04 2003-11-06 Chiron Corporation Novel guanidinyl derivatives
US20050124652A1 (en) * 2002-02-04 2005-06-09 Rustum Boyce Guanidino compounds
US20030195187A1 (en) * 2002-02-04 2003-10-16 Chiron Corporation Guanidino compounds
US20070004743A1 (en) * 2002-02-25 2007-01-04 Xiao Linda L Intranasal administration of mc4-r agonists
US7034033B2 (en) 2002-05-23 2006-04-25 Chiron Corporation Substituted quinazolinone compounds
CA2488725A1 (en) * 2002-07-03 2004-01-15 Su Qian Agouti-related protein deficient cells, non-human transgenic animals and methods of selecting compounds which regulate energy metabolism
AU2004249120B2 (en) * 2003-05-23 2008-07-24 Glaxosmithkline Guanidino-substituted quinazolinone compounds as MC4-R agonists
ES2391457T3 (es) * 2003-08-13 2012-11-26 Sandoz Ag Procedimiento para la purificación de polipéptidos recombinantes
EP1686996A4 (de) * 2003-11-19 2008-11-12 Novartis Vaccines & Diagnostic Chinazolinon-verbindungen mit verringerter bioakkumulation
US6974187B2 (en) * 2004-01-28 2005-12-13 Tachi-S Co., Ltd. Vehicle seat structure
BRPI0510095A (pt) * 2004-04-20 2007-10-16 Transtech Pharma Inc tiazol substituìdo e derivados de pirimidina como moduladores de receptores de melanocortina
US7910101B2 (en) 2004-10-25 2011-03-22 Centocor, Inc. Melanocortin receptor binding mimetibodies, compositions, methods and uses
US20070021433A1 (en) 2005-06-03 2007-01-25 Jian-Qiang Fan Pharmacological chaperones for treating obesity
US7833927B2 (en) * 2005-08-31 2010-11-16 Rohm And Haas Company Single site palladium catalyst complexes
WO2010025142A1 (en) * 2008-08-29 2010-03-04 Transtech Pharma, Inc. Substituted aminothiazole derivatives, pharmaceutical compositions, and methods of use
CA2825098C (en) 2011-01-27 2020-03-10 Universite De Montreal Pyrazolopyridine and pyrazolopyrimidine derivatives as melanocortin-4 receptor modulators

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US4263428A (en) * 1978-03-24 1981-04-21 The Regents Of The University Of California Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
ATE12348T1 (de) * 1980-11-10 1985-04-15 Gersonde Klaus Prof Dr Verfahren zur herstellung von lipid-vesikeln durch ultraschallbehandlung, anwendung des verfahrens und vorrichtung zur durchfuehrung des verfahrens.
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
EP0088046B1 (de) * 1982-02-17 1987-12-09 Ciba-Geigy Ag Lipide in wässriger Phase
DE3474511D1 (en) * 1983-11-01 1988-11-17 Terumo Corp Pharmaceutical composition containing urokinase
EP0154316B1 (de) * 1984-03-06 1989-09-13 Takeda Chemical Industries, Ltd. Chemisch modifizierte Lymphokine und Verfahren zu ihrer Herstellung
DE68925966T2 (de) * 1988-12-22 1996-08-29 Kirin Amgen Inc Chemisch modifizierte granulocytenkolonie erregender faktor
US5252714A (en) * 1990-11-28 1993-10-12 The University Of Alabama In Huntsville Preparation and use of polyethylene glycol propionaldehyde
US5766877A (en) * 1996-05-10 1998-06-16 Amgen Inc. Genes encoding art, an agouti-related transcript

Also Published As

Publication number Publication date
US6203995B1 (en) 2001-03-20
JP4219404B2 (ja) 2009-02-04
AU2681497A (en) 1997-12-05
US6060589A (en) 2000-05-09
ES2234015T3 (es) 2005-06-16
CA2253238C (en) 2008-08-12
WO1997043412A1 (en) 1997-11-20
EP0917571A1 (de) 1999-05-26
SI0917571T1 (en) 2005-06-30
DE69731834T2 (de) 2005-12-15
DK0917571T3 (da) 2005-03-14
US7122520B2 (en) 2006-10-17
US5766877A (en) 1998-06-16
US20010007752A1 (en) 2001-07-12
US20030082737A1 (en) 2003-05-01
JP2001517931A (ja) 2001-10-09
PT917571E (pt) 2005-04-29
CA2253238A1 (en) 1997-11-20
ATE283917T1 (de) 2004-12-15
EP0917571B1 (de) 2004-12-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee