DE69733958D1 - Verfahren zur positionierung von klonen mittels molekularen kaemmens - Google Patents

Verfahren zur positionierung von klonen mittels molekularen kaemmens

Info

Publication number
DE69733958D1
DE69733958D1 DE69733958T DE69733958T DE69733958D1 DE 69733958 D1 DE69733958 D1 DE 69733958D1 DE 69733958 T DE69733958 T DE 69733958T DE 69733958 T DE69733958 T DE 69733958T DE 69733958 D1 DE69733958 D1 DE 69733958D1
Authority
DE
Germany
Prior art keywords
dna
probes
several
reacting
combing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69733958T
Other languages
English (en)
Other versions
DE69733958T2 (de
Inventor
Aaron Bensimon
David Bensimon
Xavier Michalet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Institut Pasteur de Lille
Original Assignee
Centre National de la Recherche Scientifique CNRS
Institut Pasteur de Lille
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9613276A external-priority patent/FR2755147B1/fr
Application filed by Centre National de la Recherche Scientifique CNRS, Institut Pasteur de Lille filed Critical Centre National de la Recherche Scientifique CNRS
Application granted granted Critical
Publication of DE69733958D1 publication Critical patent/DE69733958D1/de
Publication of DE69733958T2 publication Critical patent/DE69733958T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/10—Ploidy or copy number detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Medical Informatics (AREA)
  • Evolutionary Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Lasers (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Position Fixing By Use Of Radio Waves (AREA)
  • Control Of Stepping Motors (AREA)
DE69733958T 1996-10-30 1997-10-30 Verfahren zur positionierung von klonen mittels molekularen kaemmens Expired - Lifetime DE69733958T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
FR9613276 1996-10-30
FR9613276A FR2755147B1 (fr) 1996-10-30 1996-10-30 Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic
FR9702999 1997-03-13
FR9702999A FR2755149B1 (fr) 1996-10-30 1997-03-13 Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic
PCT/FR1997/001949 WO1998018959A1 (fr) 1996-10-30 1997-10-30 Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic

Publications (2)

Publication Number Publication Date
DE69733958D1 true DE69733958D1 (de) 2005-09-15
DE69733958T2 DE69733958T2 (de) 2006-05-18

Family

ID=26233071

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69733958T Expired - Lifetime DE69733958T2 (de) 1996-10-30 1997-10-30 Verfahren zur positionierung von klonen mittels molekularen kaemmens

Country Status (10)

Country Link
US (4) US6344319B1 (de)
EP (1) EP0935674B1 (de)
JP (3) JP4226078B2 (de)
AT (1) ATE301724T1 (de)
AU (1) AU4953397A (de)
DE (1) DE69733958T2 (de)
DK (1) DK0935674T3 (de)
ES (1) ES2247623T3 (de)
FR (1) FR2755149B1 (de)
WO (1) WO1998018959A1 (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2755149B1 (fr) * 1996-10-30 1999-01-15 Pasteur Institut Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic
US6696022B1 (en) * 1999-08-13 2004-02-24 U.S. Genomics, Inc. Methods and apparatuses for stretching polymers
AU2001290505A1 (en) * 2000-03-28 2001-12-11 Dana-Farber Cancer Institute, Inc. Molecular database for antibody characterization
WO2002101353A2 (en) * 2001-06-08 2002-12-19 U.S. Genomics, Inc. Methods and products for analyzing nucleic acids based on methylation status
US20030054386A1 (en) * 2001-06-22 2003-03-20 Stylianos Antonarakis Method for detecting diseases caused by chromosomal imbalances
JP2005504275A (ja) * 2001-09-18 2005-02-10 ユー．エス． ジェノミクス， インコーポレイテッド 高分解能線形解析用のポリマーの差示的タグ付け
US7282330B2 (en) * 2002-05-28 2007-10-16 U.S. Genomics, Inc. Methods and apparati using single polymer analysis
US7371520B2 (en) * 2002-05-28 2008-05-13 U.S. Genomics, Inc. Methods and apparati using single polymer analysis
US6952651B2 (en) * 2002-06-17 2005-10-04 Intel Corporation Methods and apparatus for nucleic acid sequencing by signal stretching and data integration
NL1021160C2 (nl) * 2002-07-26 2004-01-27 Multigen Internat B V Werkwijze voor het bepalen van het kopieaantal van een nucleotidevolgorde.
WO2004038037A2 (en) * 2002-09-20 2004-05-06 Intel Corporation Controlled alignment of nano-barcodes encoding specific information for scanning probe microscopy (spm) reading
US7361821B2 (en) * 2002-09-20 2008-04-22 Intel Corporation Controlled alignment of nanobarcodes encoding specific information for scanning probe microscopy (SPM) reading
US7606403B2 (en) * 2002-10-17 2009-10-20 Intel Corporation Model-based fusion of scanning probe microscopic images for detection and identification of molecular structures
US7704687B2 (en) * 2002-11-15 2010-04-27 The Johns Hopkins University Digital karyotyping
WO2005012575A1 (en) * 2003-08-01 2005-02-10 U.S. Genomics, Inc. Methods and compositions related to the use of sequence-specific endonucleases for analyzing nucleic acids under non-cleaving conditions
US20050064435A1 (en) * 2003-09-24 2005-03-24 Xing Su Programmable molecular barcodes
US20050147976A1 (en) * 2003-12-29 2005-07-07 Xing Su Methods for determining nucleotide sequence information
US20050151126A1 (en) * 2003-12-31 2005-07-14 Intel Corporation Methods of producing carbon nanotubes using peptide or nucleic acid micropatterning
US20050221408A1 (en) * 2004-03-19 2005-10-06 U.S. Genomics, Inc. Compositions and methods for detection of single molecules
US7736818B2 (en) 2004-12-27 2010-06-15 Inphase Technologies, Inc. Holographic recording medium and method of making it
JP4656145B2 (ja) * 2005-09-05 2011-03-23 株式会社島津製作所 生体高分子固定用基板及びそれを用いた生体高分子固定方法
WO2007076132A2 (en) 2005-12-23 2007-07-05 Nanostring Technologies, Inc. Compositions comprising oriented, immobilized macromolecules and methods for their preparation
JP5537034B2 (ja) 2005-12-23 2014-07-02 ナノストリング テクノロジーズ，インコーポレーテッド ナノレポーターならびにその作製方法および使用方法
WO2007095007A2 (en) * 2006-02-14 2007-08-23 Albert Einstein College Of Medicine Of Yeshiva University Systematic genomic library and uses thereof
ES2620398T3 (es) * 2006-05-22 2017-06-28 Nanostring Technologies, Inc. Sistemas y métodos para analizar nanoindicadores
US9061901B2 (en) 2006-07-19 2015-06-23 Bionano Genomics, Inc. Nanonozzle device arrays: their preparation and use for macromolecular analysis
JP5211790B2 (ja) * 2007-03-26 2013-06-12 住友化学株式会社 Ｄｎａメチル化測定方法
CN103305402A (zh) 2007-03-28 2013-09-18 博纳基因技术有限公司 使用纳米通道阵列的大分子分析方法
WO2008124847A2 (en) * 2007-04-10 2008-10-16 Nanostring Technologies, Inc. Methods and computer systems for identifying target-specific sequences for use in nanoreporters
JP5260981B2 (ja) * 2008-02-22 2013-08-14 株式会社日立ハイテクノロジーズ 真空処理装置
AU2009267086B2 (en) 2008-06-30 2016-01-14 Bionano Genomics, Inc. Methods and devices for single-molecule whole genome analysis
JP2010068800A (ja) * 2008-08-19 2010-04-02 Sumitomo Chemical Co Ltd Ｄｎａを定量又は検出する方法
EP2175037B1 (de) 2008-09-26 2017-10-11 Genomic Vision Verfahren zur Analyse von D4Z4-Tandemwiederholungsarrays von Nukleinsäure und Kit dafür
CN102292454B (zh) 2008-11-18 2014-11-26 博纳基因技术有限公司 多核苷酸作图和测序
WO2010115122A2 (en) * 2009-04-03 2010-10-07 Illumina, Inc. Generation of uniform fragments of nucleic acids using patterned substrates
CA2796294C (en) 2010-04-23 2019-03-26 Genomic Vision Diagnosis of viral infections by detection of genomic and infectious viral dna by molecular combing
DK2619325T3 (en) 2010-09-24 2016-09-05 Genomic Vision A method for recording, quantification and identification of damage and / or repair of the DNA strands
CA2837554A1 (en) 2011-06-03 2012-12-06 Genomic Vision Assessment of cancer risk based on rnu2 cnv and interplay between rnu2 cnv and brca1
EP2773770A1 (de) * 2011-10-31 2014-09-10 Genomic Vision Verfahren zur identifizierung oder erkennung von genomneuanordnungen in einer biologischen probe
US9028776B2 (en) 2012-04-18 2015-05-12 Toxic Report Llc Device for stretching a polymer in a fluid sample
JP2016521575A (ja) 2013-06-14 2016-07-25 ナノストリング テクノロジーズ，インコーポレイティド 多重化可能なタグベースのレポーターシステム
US20180135080A1 (en) 2016-11-15 2018-05-17 Genomic Vision Sa Method for the monitoring of modified nucleases induced-gene editing events by molecular combing
EP3548637A1 (de) 2016-11-29 2019-10-09 Genomic Vision Verfahren zum entwurf eines satzes von polynukleotidsequenzen zur analyse von spezifischen ereignissen in einer genetischen region von interesse
CN111566211A (zh) * 2017-11-29 2020-08-21 X基因组公司 新兴的核酸测序技术
EP3976828A4 (de) * 2019-05-29 2023-06-28 XGenomes Corp. Sequenzierung nach emergenz
JP7456776B2 (ja) 2020-01-16 2024-03-27 日清紡マイクロデバイス株式会社 炭化珪素半導体装置の製造方法
CN115997030A (zh) 2020-04-30 2023-04-21 德迈逊科技有限公司 用于大分子操作的装置和方法
WO2021247394A1 (en) 2020-06-01 2021-12-09 Dimensiongen Devices and methods for genomic analysis
CN115803460A (zh) 2020-08-10 2023-03-14 德迈逊科技有限公司 用于多维基因组分析的装置和方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079169A (en) * 1990-05-22 1992-01-07 The Regents Of The Stanford Leland Junior University Method for optically manipulating polymer filaments
JP3123249B2 (ja) * 1991-09-10 2001-01-09 株式会社日立製作所 Ｄｎａ分子の長さ計測方法および計測装置
ATE205542T1 (de) * 1992-03-04 2001-09-15 Univ California Vergleichende genomhybridisierung
WO1994016104A1 (en) * 1993-01-08 1994-07-21 Ctrc Research Foundation Color imaging system for use in molecular biology
US5472842A (en) * 1993-10-06 1995-12-05 The Regents Of The University Of California Detection of amplified or deleted chromosomal regions
WO1995014106A2 (en) 1993-11-17 1995-05-26 Id Biomedical Corporation Cycling probe cleavage detection of nucleic acid sequences
FR2716263B1 (fr) 1994-02-11 1997-01-17 Pasteur Institut Procédé d'alignement de macromolécules par passage d'un ménisque et applications dans un procédé de mise en évidence, séparation et/ou dosage d'une macromolécule dans un échantillon.
US5830645A (en) * 1994-12-09 1998-11-03 The Regents Of The University Of California Comparative fluorescence hybridization to nucleic acid arrays
US5851769A (en) * 1995-09-27 1998-12-22 The Regents Of The University Of California Quantitative DNA fiber mapping
CA2235395A1 (en) * 1995-11-13 1997-05-22 Institut Pasteur Ultrahigh resolution comparative nucleic acid hybridization to combed dna fibers
FR2755149B1 (fr) * 1996-10-30 1999-01-15 Pasteur Institut Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic

Also Published As

Publication number Publication date
JP4223538B2 (ja) 2009-02-12
ATE301724T1 (de) 2005-08-15
JP4223539B2 (ja) 2009-02-12
FR2755149A1 (fr) 1998-04-30
ES2247623T3 (es) 2006-03-01
US6344319B1 (en) 2002-02-05
JP2001507929A (ja) 2001-06-19
EP0935674B1 (de) 2005-08-10
AU4953397A (en) 1998-05-22
JP4226078B2 (ja) 2009-02-18
WO1998018959A1 (fr) 1998-05-07
US20040033510A1 (en) 2004-02-19
US7368234B2 (en) 2008-05-06
JP2008061651A (ja) 2008-03-21
EP0935674A1 (de) 1999-08-18
US20090123926A1 (en) 2009-05-14
US7732143B2 (en) 2010-06-08
FR2755149B1 (fr) 1999-01-15
US20020048767A1 (en) 2002-04-25
JP2008067716A (ja) 2008-03-27
DE69733958T2 (de) 2006-05-18
DK0935674T3 (da) 2005-12-05

Similar Documents

Publication Publication Date Title
DE69733958D1 (de) Verfahren zur positionierung von klonen mittels molekularen kaemmens
DE1073770T1 (de) Neuartiges Verfahren zur Identifizierung von Klonen mit einer gewünschten Biologischen Eigenschaft, ausgehend von einer Expressionsgenbank (2001/06)
DE69535802D1 (de) Genetische veränderungen, die mit lungencarzinomen korrelieren
MY132156A (en) Detecting genetic predisposition to periodontal disease
NO986133D0 (no) FremgangsmÕte for DNA-sekvensering
CO4870792A1 (es) Compuestos y conjunto de medios de diagnostico para detectar y vigilar la progresion de cancer de prostata
MXPA04003926A (es) Metodos para detectar haplotipos geneticos por interaccion con sondas.
DE60045188D1 (de) T-ZELLREZEPTOR Vb-Db-Jb-SEQUENZ UND VERFAHREN FÜR IHREN NACHWEIS
DE69704031D1 (de) Test zur diagnose eines erhöhten brustkrebs-risikos
WO1991012343A3 (en) Detection of point mutations in genes encoding gtp binding proteins
ATE168696T1 (de) 5'(oh) und/oder 3'(oh) zur einführung von einem oder mehreren nichtradioaktivmarkierten markern chemisch modifizierte nukleinsäuresonden, und verfahren zu ihrer herstellung
DE602004019067D1 (de) Verfahren zum nachweis des gens einer beta-3-adrenalinrezeptor-mutante sowie nukleinsäuresonde und kit dafür
DE69225797D1 (de) Nukleinsäure fragment des x-chromosomen bereichs beteiligt am empfindlichen x-syndrom, nukleotidische sonde und verfahren für die diagnose von geistiger zurückgebliebenheit mit empfindlichem x
DE602004020603D1 (de) Verfahren zum nachweis des gens einer mutante des pankreatischen insel-amyloidproteins sowie nukleinsäuresonde und kit dafür
ATE367451T1 (de) Hochauflösende genkartierungs verfahren und genkartierungs sonden
ATE329044T1 (de) Gen, das im zusammenhang steht mit gemütskrankheiten
KR20050119274A (ko) 초위성체 유전자를 이용한 돈육의 원산지 추적 및개체식별 방법
CA2259657A1 (en) Identification of a transforming fragment of herpes simplex type 2 and detection thereof in clinical specimens
FR2710655B1 (fr) Procédé pour effectuer un test biologique destiné à identifier et à doser des gènes, des protéines et autres molécules.
WO2003104475A3 (en) ATM PROTEIN ASSOCIATED KINASE ATX, NECLEIC ACIDS ENCODING THE KINASE AND METHODS OF USE

Legal Events

Date Code Title Description
8364 No opposition during term of opposition