DE69737413D1 - Bakterioferritin aus helicobacter pylori - Google Patents

Bakterioferritin aus helicobacter pylori

Info

Publication number
DE69737413D1
DE69737413D1 DE69737413T DE69737413T DE69737413D1 DE 69737413 D1 DE69737413 D1 DE 69737413D1 DE 69737413 T DE69737413 T DE 69737413T DE 69737413 T DE69737413 T DE 69737413T DE 69737413 D1 DE69737413 D1 DE 69737413D1
Authority
DE
Germany
Prior art keywords
bakterioferritin
aus
helicobacter pylori
pylori
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69737413T
Other languages
English (en)
Other versions
DE69737413T2 (de
Inventor
William Byrne
Dermot Kelleher
Henry Windle
Ross Mcmanus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin
Original Assignee
Novartis Vaccines and Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Vaccines and Diagnostics Inc filed Critical Novartis Vaccines and Diagnostics Inc
Publication of DE69737413D1 publication Critical patent/DE69737413D1/de
Application granted granted Critical
Publication of DE69737413T2 publication Critical patent/DE69737413T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/205Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
DE69737413T 1996-01-04 1997-01-03 Bakterioferritin aus helicobacter pylori Expired - Lifetime DE69737413T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IE960004 1996-01-04
IE960004 1996-01-04
IE960019 1996-01-12
IE960019 1996-01-12
PCT/IE1997/000001 WO1997025429A1 (en) 1996-01-04 1997-01-03 Helicobacter pylori bacterioferritin

Publications (2)

Publication Number Publication Date
DE69737413D1 true DE69737413D1 (en) 2007-04-12
DE69737413T2 DE69737413T2 (de) 2007-10-31

Family

ID=26319876

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69737413T Expired - Lifetime DE69737413T2 (de) 1996-01-04 1997-01-03 Bakterioferritin aus helicobacter pylori

Country Status (10)

Country Link
US (1) US7901907B2 (de)
EP (1) EP0909323B1 (de)
AT (1) ATE355375T1 (de)
AU (1) AU1463097A (de)
DE (1) DE69737413T2 (de)
DK (1) DK0909323T3 (de)
ES (1) ES2283012T3 (de)
GB (1) GB2324093A (de)
PT (1) PT909323E (de)
WO (1) WO1997025429A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7141244B1 (en) * 1992-03-02 2006-11-28 Chiron Srl Helicobacter pylori proteins useful for vaccines and diagnostics
WO1996001272A1 (en) * 1994-07-01 1996-01-18 Rican Limited Helicobacter proteins and vaccines
EP0909323B1 (de) 1996-01-04 2007-02-28 Novartis Vaccines and Diagnostics, Inc. Bakterioferritin aus helicobacter pylori
GB9807721D0 (en) * 1998-04-08 1998-06-10 Chiron Spa Antigen
GB0115176D0 (en) 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
GB0220194D0 (en) 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
EP2279746B1 (de) 2002-11-15 2013-10-02 Novartis Vaccines and Diagnostics S.r.l. Oberflächenproteine in neisseria meningitidis
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
GB0308198D0 (en) 2003-04-09 2003-05-14 Chiron Srl ADP-ribosylating bacterial toxin
GB0700562D0 (en) 2007-01-11 2007-02-21 Novartis Vaccines & Diagnostic Modified Saccharides
CA2737455A1 (en) 2008-09-18 2010-03-25 Novartis Ag Vaccine adjuvant combinations
CN102740882A (zh) 2009-08-27 2012-10-17 诺华有限公司 含有铝、寡核苷酸和聚阳离子的佐剂
CN102844047B (zh) 2009-09-02 2017-04-05 诺华股份有限公司 含tlr活性调节剂的免疫原性组合物
EP2719395A1 (de) 2010-09-01 2014-04-16 Novartis AG Adsorption von Immunpotentiatoren auf unlöslichen Metallsalzen
EP2652511B8 (de) 2010-12-14 2017-06-28 GlaxoSmithKline Biologicals SA Durchflusszytometrische analayse von metallsalzadsorbierten stoffen
WO2012117377A1 (en) 2011-03-02 2012-09-07 Novartis Ag Combination vaccines with lower doses of antigen and/or adjuvant
HUE030175T2 (en) 2012-03-07 2017-04-28 Glaxosmithkline Biologicals Sa Arginine salt of TLR7 agonist
US20150132339A1 (en) 2012-03-07 2015-05-14 Novartis Ag Adjuvanted formulations of streptococcus pneumoniae antigens
EP2822581A2 (de) 2012-03-08 2015-01-14 Novartis AG Adjuvierte formulierungen von dtp-auffrischungsimpfstoffen

Family Cites Families (130)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751181A (en) * 1984-12-31 1988-06-14 Duke University Methods and compositions useful in the diagnosis and treatment of autoimmune diseases
US4997823A (en) * 1986-02-18 1991-03-05 Syntex (U.S.A.) Inc. Anti-infective injectable formulations
JP2634833B2 (ja) 1986-03-28 1997-07-30 ボード オブ トラステイーズ オブ ユニヴアーシテイ オブ イリノイ ヒト細胞における複数薬剤耐性に関連するdna配列を含むクローンの組成および方法
US5554372A (en) * 1986-09-22 1996-09-10 Emory University Methods and vaccines comprising surface-active copolymers
US4879213A (en) * 1986-12-05 1989-11-07 Scripps Clinic And Research Foundation Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse
US5459041A (en) * 1988-02-18 1995-10-17 Enteric Research Laboratories, Inc. Campylobacter pylori antigens and uses thereof for detection of Campylobacter pylori infection
US4882271A (en) * 1988-03-10 1989-11-21 Baylor College Of Medicine Process for preparation of high molecular weight cell-associated protein of campylobacter pylori and use for serological detection of campylobacter pylori infection
GB8815795D0 (en) 1988-07-02 1988-08-10 Bkl Extrusions Ltd Glazing bead
FR2637612B1 (fr) 1988-10-06 1993-09-10 Pasteur Institut Sequences de nucleotides codant pour une proteine a activite ureasique
DE3841091A1 (de) 1988-12-07 1990-06-13 Behringwerke Ag Synthetische antigene, verfahren zu ihrer herstellung und ihre verwendung
JP3436756B2 (ja) 1988-12-19 2003-08-18 アメリカン・サイアナミド・カンパニー 髄膜炎菌のクラスiの外膜タンパク質のワクチン
CA2006700A1 (en) 1989-01-17 1990-07-17 Antonello Pessi Synthetic peptides and their use as universal carriers for the preparation of immunogenic conjugates suitable for the development of synthetic vaccines
HU212924B (en) 1989-05-25 1996-12-30 Chiron Corp Adjuvant formulation comprising a submicron oil droplet emulsion
IT1237764B (it) 1989-11-10 1993-06-17 Eniricerche Spa Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici.
GB8928625D0 (en) 1989-12-19 1990-02-21 3I Res Expl Ltd H.pylori dna probes
US5292658A (en) * 1989-12-29 1994-03-08 University Of Georgia Research Foundation, Inc. Boyd Graduate Studies Research Center Cloning and expressions of Renilla luciferase
JPH04364160A (ja) * 1990-08-03 1992-12-16 Terumo Corp チオウレア誘導体およびこれを含有する抗菌剤および抗潰瘍剤
ATE128628T1 (de) 1990-08-13 1995-10-15 American Cyanamid Co Faser-hemagglutinin von bordetella pertussis als träger für konjugierten impfstoff.
US5153312A (en) 1990-09-28 1992-10-06 American Cyanamid Company Oligosaccharide conjugate vaccines
DE4139840B4 (de) 1990-12-04 2005-06-02 Quidel Corp., San Diego Antigen-Zubereitung zum Nachweis von H. pylori
US5567594A (en) * 1991-04-26 1996-10-22 Enteron, L.P. Methods and compositions for the detection and treatment of diseases associated with antigens of microorganisms
US5262156A (en) * 1991-08-12 1993-11-16 Hycor Biomedical, Inc. Antigenic compositions and their use for the detection of Helicobacter pylori
ES2198514T3 (es) * 1991-08-27 2004-02-01 F. Hoffmann-La Roche Ag Cebadores y sondas para la deteccion de la hepatitis c.
JPH0559038A (ja) * 1991-09-06 1993-03-09 Terumo Corp チオウレア誘導体及びこれを含有する医薬製剤
IT1251751B (it) * 1991-10-31 1995-05-23 Sclavo Ricerca S R L Metodo per la coltura di microrganismi dei generi helicobacter, campylobacter e arcobacter, utilizzando terreni di coltura contenenti ciclodestrine o metil-cellulosa o loro miscele
US5866375A (en) * 1991-10-31 1999-02-02 Chiron S.P.A. Method for the culture of microorganisms of the genera helicobacter, campylobacter and arcobacter employing culture media comprising cyclodextrins
US5354854A (en) * 1991-11-07 1994-10-11 The Curators Of The University Of Missouri Expression system for use in plants to suppress foreign expression and method
WO1993016723A1 (en) 1992-02-26 1993-09-02 Vanderbilt University Purified vacuolating toxin from helicobacter pylori and methods to use same
US5721349A (en) * 1992-02-26 1998-02-24 Vanderbilt University Vacuolating toxin-deficient H. pylori
DE69333110T2 (de) * 1992-03-02 2004-05-06 Chiron S.P.A. Mit dem cytotoxin von helicobacter pylori assoziiertes, immunodominantes antigen verwendbar in impfstoffen und zur diagnose
US7141244B1 (en) 1992-03-02 2006-11-28 Chiron Srl Helicobacter pylori proteins useful for vaccines and diagnostics
IT1262895B (it) * 1992-03-02 1996-07-22 Proteina estratta da ceppi citotossici di helicobacter pylori, gene che la esprime, uso della proteina come vaccino o diagnostico.
IT1262896B (it) * 1992-03-06 1996-07-22 Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini.
MX9301706A (es) * 1992-04-13 1994-05-31 Oravax Inc Composicion de vacuna para el tratamiento de la infeccion por helicobacter.
EP0761231B1 (de) 1992-06-25 2000-01-12 SMITHKLINE BEECHAM BIOLOGICALS s.a. Adjuvantien enthaltende Impfstoffzusammensetzung
US5403924A (en) * 1992-10-13 1995-04-04 Vanderbilt University Taga gene and methods for detecting predisposition to peptic ulceration
US5733740A (en) * 1992-10-13 1998-03-31 Vanderbilt University Taga gene and methods for detecting predisposition to peptic ulceration and gastric carcinoma
AU685443B2 (en) 1993-03-23 1998-01-22 Smithkline Beecham Biologicals (Sa) Vaccine compositions containing 3-O deacylated monophosphoryl lipid A
WO1995014093A1 (en) * 1993-05-19 1995-05-26 Institut Pasteur Immunogenic compositions against helicobacter infection, polypeptides for use in the compositions and nucleic acid sequences encoding said polypeptides
DE69432929T2 (de) * 1993-07-27 2004-04-15 Csl Ltd., Parkville Behandlung eines durch helicobakter verursachten gastroduodenalen krankheit
DE69435138D1 (de) * 1993-11-23 2008-10-23 Univ California Reichlich vorhandene extrazelluläre produkte und methoden zu ihrer herstellung sowie ihre verwendung
GB9326253D0 (en) 1993-12-23 1994-02-23 Smithkline Beecham Biolog Vaccines
US5434253A (en) * 1994-03-21 1995-07-18 Vanderbilt University DNA encoding Helicobacter pylori recombinase
US5571515A (en) * 1994-04-18 1996-11-05 The Wistar Institute Of Anatomy & Biology Compositions and methods for use of IL-12 as an adjuvant
AUPM612494A0 (en) * 1994-06-08 1994-06-30 Csl Limited Treatment or prevention of helicobacter infection
WO1996001272A1 (en) 1994-07-01 1996-01-18 Rican Limited Helicobacter proteins and vaccines
ES2267100T5 (es) 1994-07-15 2011-04-08 The University Of Iowa Research Foundation Oligonucleótidos inmunomoduladores.
US6207646B1 (en) 1994-07-15 2001-03-27 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US6019982A (en) * 1994-08-26 2000-02-01 The Administrators Of The Tulane Educational Fund Mutant enterotoxin effective as a non-toxic oral adjuvant
WO1996009757A1 (en) * 1994-09-28 1996-04-04 Biocine Spa Mouse model for helicobacter pylori infection
US5897475A (en) * 1994-10-05 1999-04-27 Antex Biologics, Inc. Vaccines comprising enhanced antigenic helicobacter spp.
US5527678A (en) * 1994-10-21 1996-06-18 Vanderbilt University CagB and CagC genes of helicobacter pylori and related compositions
US5861518A (en) * 1994-11-21 1999-01-19 Dekker; Koenraad A. Phthalide compounds and their production process
GB9501560D0 (en) * 1995-01-26 1995-03-15 Nycomed Imaging As Contrast agents
IL117483A (en) 1995-03-17 2008-03-20 Bernard Brodeur MENINGITIDIS NEISSERIA shell protein is resistant to proteinase K.
DE19511276C2 (de) * 1995-03-27 1999-02-18 Immuno Ag Adjuvans auf der Basis kolloidaler Eisenverbindungen
SK165197A3 (en) 1995-06-07 1999-01-11 Astra Ab Nucleic acid and amino acid sequences relating to helicobacter pylori for diagnostics and therapeutics
GB9513261D0 (en) 1995-06-29 1995-09-06 Smithkline Beecham Biolog Vaccines
US5854221A (en) * 1996-12-12 1998-12-29 The Children's Medical Center Corporation Endothelial cell proliferation inhibitor and method of use
FR2742756B1 (fr) * 1995-12-22 1998-04-03 Pasteur Merieux Serums Vacc Stabilisants pour vaccins vivants, vaccins les contenant et procedes pour leur preparation
EP0909323B1 (de) 1996-01-04 2007-02-28 Novartis Vaccines and Diagnostics, Inc. Bakterioferritin aus helicobacter pylori
DE19630390A1 (de) 1996-07-26 1998-01-29 Chiron Behring Gmbh & Co Proteine, insbesondere Membranproteine von Helicobacter pylori, ihre Herstellung und Verwendung
US5900410A (en) * 1996-08-27 1999-05-04 Hartmann; John F. Monotherapy of peptic ulcers and gastritis
US6610661B1 (en) 1996-10-11 2003-08-26 The Regents Of The University Of California Immunostimulatory polynucleotide/immunomodulatory molecule conjugates
US5980898A (en) 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
US20040052799A1 (en) * 1996-11-15 2004-03-18 Astra Aktiebolag Nucleic acid and amino acid sequences relating to Helicobacter pylori for diagnostics and therapeutics
WO1998027432A1 (en) 1996-12-19 1998-06-25 Chiron Corporation Helicobacter pylori diagnostics
US6902903B1 (en) * 1996-12-19 2005-06-07 Chiron Corporation Helicobacter pylori diagnostics
JP2001509167A (ja) * 1997-01-24 2001-07-10 エイブイアイ バイオファーマ,インコーポレイテッド H.pylori感染を処置するための方法および結合体
SE9700661D0 (sv) * 1997-02-25 1997-02-25 Astra Ab New compounds
AU738513B2 (en) 1997-02-28 2001-09-20 University Of Iowa Research Foundation, The Use of nucleic acids containing unmethylated CpG dinucleotide in the treatment of LPS-associated disorders
EP1005368B1 (de) 1997-03-10 2009-09-02 Ottawa Hospital Research Institute Verwendung von nicht-methyliertem CpG Dinukleotid in Kombination mit Aluminium als Adjuvantien
DE19709897A1 (de) * 1997-03-11 1998-09-17 Hoechst Ag Wismutsalze von Antibiotika der Moenomycin-Gruppe, Verfahren zu ihrer Herstellung, ihre Verwendung und solche Salze enthaltende Arzneimittel
IN183034B (de) 1997-03-14 1999-08-28 Ashok Patil
US6299881B1 (en) 1997-03-24 2001-10-09 Henry M. Jackson Foundation For The Advancement Of Military Medicine Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts
US20020115078A1 (en) * 1997-04-01 2002-08-22 Harold Kleanthous Identification of polynucleotides encoding novel helicobacter polypeptides in the helicobacter genome
JP4090087B2 (ja) * 1997-04-04 2008-05-28 株式会社資生堂 ベンズアミド誘導体及び抗潰瘍剤、抗菌剤
JP4113602B2 (ja) * 1997-04-04 2008-07-09 株式会社資生堂 ピロリジン誘導体及び抗潰瘍剤、抗菌剤
JP3933244B2 (ja) * 1997-04-04 2007-06-20 株式会社資生堂 アルキレンジアミン誘導体及び抗潰瘍剤、抗菌剤
IN183035B (de) 1997-04-07 1999-08-28 Shri Ashok Patil
EP1003531B1 (de) 1997-05-20 2007-08-22 Ottawa Health Research Institute Verfahren zur Herstellung von Nukleinsäurekonstrukten
EP0984969B1 (de) * 1997-05-28 2008-07-09 Nycomed GmbH Anellierte dihydropyrane
SE510650C2 (sv) 1997-05-30 1999-06-14 Astra Ab Ny förening
ATE432348T1 (de) 1997-06-06 2009-06-15 Univ California Inhibitoren von immunstimulatorischen dna sequenz aktivität
GB9712347D0 (en) 1997-06-14 1997-08-13 Smithkline Beecham Biolog Vaccine
GB9713156D0 (en) 1997-06-20 1997-08-27 Microbiological Res Authority Vaccines
SE510643C2 (sv) 1997-06-27 1999-06-14 Astra Ab Termodynamiskt stabil omeprazol natrium form B
ES2298316T3 (es) 1997-09-05 2008-05-16 Glaxosmithkline Biologicals S.A. Emulsiones de aceite en agua que contienen saponinas.
US6914131B1 (en) * 1998-10-09 2005-07-05 Chiron S.R.L. Neisserial antigens
ATE476508T1 (de) 1997-11-06 2010-08-15 Novartis Vaccines & Diagnostic Neisseriale antigene
PT1032674E (pt) * 1997-11-21 2007-03-30 Serono Genetics Inst Sa Sequência genómica e polipéptidos (de chlamydia pneumoniae), seus fragmentos e suas utilizações, em particular para o diagnóstico, prevenção e tratamento de infacção
WO1999027105A2 (en) 1997-11-21 1999-06-03 Genset Chlamydia pneumoniae genomic sequence and polypeptides, fragments thereof and uses thereof, in particular for the diagnosis, prevention and treatment of infection
SE9704404D0 (sv) 1997-11-28 1997-11-28 Astra Ab New compounds
KR100760221B1 (ko) 1997-11-28 2007-10-30 세로노 제네틱스 인스티튜트 에스.에이. 클라미디아 트라코마티스 게놈 서열과 폴리펩티드, 이의단편 및 이의 용도, 특히, 감염의 진단, 예방 및 치료 용도
WO1999036544A2 (en) 1998-01-14 1999-07-22 Chiron S.P.A. Neisseria meningitidis antigens
US6303114B1 (en) 1998-03-05 2001-10-16 The Medical College Of Ohio IL-12 enhancement of immune responses to T-independent antigens
GB9807721D0 (en) 1998-04-08 1998-06-10 Chiron Spa Antigen
HUP0101619A3 (en) 1998-04-09 2003-11-28 Smithkline Beecham Biolog Adjuvant compositions
JP4346821B2 (ja) * 1998-04-30 2009-10-21 カイロン ソチエタ ア レスポンサビリタ リミタータ H.Pyloriによる感染に対する免疫化および処置
EP2261349A3 (de) 1998-05-01 2012-01-11 Novartis Vaccines and Diagnostics, Inc. Antigene und Zusammensetzungen gegen Neisseria meningitidis
US6248329B1 (en) * 1998-06-01 2001-06-19 Ramaswamy Chandrashekar Parasitic helminth cuticlin nucleic acid molecules and uses thereof
GB9817052D0 (en) 1998-08-05 1998-09-30 Smithkline Beecham Biolog Vaccine
EP1144998A3 (de) * 1998-10-09 2002-08-07 Chiron Corporation Genomische sequenzen von neisseria und verfahren zu ihrer verwendung
PL201482B1 (pl) 1998-10-16 2009-04-30 Smithkline Beecham Biolog Sposoby wytwarzania kompozycji szczepionki oraz kompozycja szczepionki
CA2350775A1 (en) 1998-11-12 2000-05-18 The Regents Of The University Of California Chlamydia pneumoniae genome sequence
WO2000028988A1 (en) * 1998-11-17 2000-05-25 Nitromed, Inc. Nitrosated and nitrosylated h2 receptor antagonist compounds, compositions and methods of use
GB9828000D0 (en) 1998-12-18 1999-02-10 Chiron Spa Antigens
US20020065296A1 (en) * 1999-01-13 2002-05-30 Bayer Corporation Heteroaryl ureas containing nitrogen hetero-atoms as p38 kinase inhibitors
EP2298311B1 (de) * 1999-01-13 2012-05-09 Bayer HealthCare LLC Omega-carboxyarylsubstituierte-Diphenyl-Harnstoffe als p38-Kinasehemmer
SI1163000T1 (sl) 1999-03-19 2008-06-30 Glaxosmithkline Biolog Sa Vakcina proti antigenom iz bakterij
FR2791895B1 (fr) 1999-03-23 2001-06-15 Pasteur Merieux Serums Vacc Utilisation de trehalose pour stabiliser un vaccin liquide
US6346283B1 (en) * 1999-03-26 2002-02-12 Ancile Pharmaceuticals Use of valeriana for the treatment of restless leg syndrome and related disorders
WO2000061761A2 (en) 1999-04-09 2000-10-19 Techlab, Inc. Recombinant clostridium toxin a protein carrier for polysaccharide conjugate vaccines
PL203951B1 (pl) 1999-04-19 2009-11-30 Smithkline Beecham Biolog Kompozycja adiuwantowa, kompozycja szczepionki oraz sposób jej wytwarzania, szczepionka oraz zastosowanie
EP1214053A1 (de) 1999-09-24 2002-06-19 SMITHKLINE BEECHAM BIOLOGICALS s.a. Adjuvans enthaltend ein polyoxyethylenalkyl ether oder ester und zumindest ein nichtionisches oberflächenaktives mittel
TR200200774T2 (tr) 1999-09-24 2002-08-21 Smithkline Beecham Biologicals S.A. Aşılar.
WO2001026681A2 (en) * 1999-10-13 2001-04-19 Chiron Corporation Method of obtaining cellular immune responses from proteins
GB9928196D0 (en) * 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
AU782971B2 (en) * 1999-12-23 2005-09-15 Nicox S.A. Nitrosated and nitrosylated cyclooxygenase-2 inhibitors, compositions and methods of use
EP2275129A3 (de) 2000-01-17 2013-11-06 Novartis Vaccines and Diagnostics S.r.l. Ergänzter Außenmembranvesikel-Impfstoff gegen Meningokokken
AU2001258102B2 (en) * 2000-05-10 2007-03-01 Aventis Pasteur Limited Immunogenic polypeptides encoded by mage minigenes and uses thereof
US20040005667A1 (en) * 2000-07-03 2004-01-08 Giuloi Ratti Immunisation against chlamydia pneumoniae
CA2425303A1 (en) 2000-10-27 2002-05-02 John Telford Nucleic acids and proteins from streptococcus groups a & b
GB0029919D0 (en) 2000-12-07 2001-01-24 Chiron Spa Helicobacter pylori prime & boost vaccination
US20030232324A1 (en) * 2001-05-31 2003-12-18 Chiron Corporation Chimeric alphavirus replicon particles
US20040029129A1 (en) * 2001-10-25 2004-02-12 Liangsu Wang Identification of essential genes in microorganisms
US20090100536A1 (en) * 2001-12-04 2009-04-16 Monsanto Company Transgenic plants with enhanced agronomic traits
US20090158452A1 (en) * 2001-12-04 2009-06-18 Johnson Richard G Transgenic plants with enhanced agronomic traits
US7310685B2 (en) 2002-08-29 2007-12-18 International Business Machines Corporation Method and system for reducing look-up time in packet forwarding on computer networks
DE602005014481D1 (de) 2005-09-23 2009-06-25 Prete Gianfranco Del Verwendung des Neutrophil-activating-protein von Helicobacter pylori und/oder Teile davon als Adjuvant für die Induktion einer T-helper type 1 (TH1) Immunantwort

Also Published As

Publication number Publication date
GB9814538D0 (en) 1998-09-02
GB2324093A (en) 1998-10-14
DE69737413T2 (de) 2007-10-31
PT909323E (pt) 2007-06-04
DK0909323T3 (da) 2007-05-21
US7901907B2 (en) 2011-03-08
ATE355375T1 (de) 2006-03-15
EP0909323B1 (de) 2007-02-28
WO1997025429A1 (en) 1997-07-17
US20070110765A1 (en) 2007-05-17
ES2283012T3 (es) 2007-10-16
EP0909323A1 (de) 1999-04-21
AU1463097A (en) 1997-08-01

Similar Documents

Publication Publication Date Title
DE69737413D1 (en) Bakterioferritin aus helicobacter pylori
GB2303854B (en) Helicobacter proteins and vaccines
ES2068907T3 (es) Secuencias de nucleotidos que codifican una proteina con actividad ureasica.
DE69333802D1 (de) Äusseres membranprotein von haemophilus
DE3588254D1 (de) Gag-Antigen und dessen Verwendung zum Nachweis von LAV-Infektion, sowie in immunogenen Zusammensetzungen
EP0109942A3 (en) Immunogenic protein or peptide complex, method of producing said complex and the use thereof as an immune stimulant and as a vaccine
BR9608615A (pt) Vacinas de vírus sincicial respiratório de ácido nucléico
EP0306219A3 (de) HIV-Proteine und Peptide zur Verwendung in Diagnose, Prophylaxe und Therapie von AIDS
DE69836520D1 (de) Clostridium perfringens Impfstoff
NZ332565A (en) Nucleic acid and amino acid sequences relating to helicobacter pylori and vaccine compositions thereof
EP0161095A3 (de) Vakzin gegen Harninfektionen
EP0236977A3 (de) Impfstoffe gegen Rindervirus-Diarrhoe und Schweine-Cholera
AU684317B2 (en) Coccidiosis poultry vaccine
NZ335633A (en) Production of recombinant H. pylori polypeptides for treatment and diagnosis of H. pylori related diseases
EA200100395A1 (ru) Фармацевтическая композиция, содержащая фрагменты днк, кодирующей антигенный белок, обладающая противоопухолевым действием
ZA957701B (en) Coccidiosis poultry vaccine
WO1997039029A3 (en) An antigenic epitope of the a determinant of hepatitis b surface antigen and uses thereof
DE69031996T2 (de) Menschlicher rekombinanter plazentaler ribonuklease-inhibitor und verfahren zur herstellung
WO1998040497A3 (en) An ex vivo animal or challenge model as method to measure protective immunity directed against parasites and vaccines shown to be protective in said method
EP0317279A3 (de) Peptide für die Verwendung zur Reinigung von Faktor-VIII
ES2017258A6 (es) Un metodo para producir peptidos antigenicos relacionados con el antigeno p97 asociado a melanoma.
MX9700215A (es) Proteinas y vacunas de helicobacter.
WO2000046242A3 (en) 19 KILODALTON PROTEIN OF $i(HELICOBACTER PYLORI)
IT1249703B (it) Sequenza di nucleotidi codificante per una porzione di proteina allergenica di piante appartenenti al genere parietaria.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLE, IE