DE69738527D1 - Konfokales Mikroskop als Handgerät zur Bilderzeugung durch dickes Hautgewebe - Google Patents

Konfokales Mikroskop als Handgerät zur Bilderzeugung durch dickes Hautgewebe

Info

Publication number
DE69738527D1
DE69738527D1 DE69738527T DE69738527T DE69738527D1 DE 69738527 D1 DE69738527 D1 DE 69738527D1 DE 69738527 T DE69738527 T DE 69738527T DE 69738527 T DE69738527 T DE 69738527T DE 69738527 D1 DE69738527 D1 DE 69738527D1
Authority
DE
Germany
Prior art keywords
imaging
handheld device
skin tissue
confocal microscope
thick skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69738527T
Other languages
English (en)
Other versions
DE69738527T2 (de
Inventor
James M Zavislan
Jay M Eastman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lucid Inc
Original Assignee
Lucid Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lucid Inc filed Critical Lucid Inc
Application granted granted Critical
Publication of DE69738527D1 publication Critical patent/DE69738527D1/de
Publication of DE69738527T2 publication Critical patent/DE69738527T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/444—Evaluating skin marks, e.g. mole, nevi, tumour, scar
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0064—Body surface scanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0066—Optical coherence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0068—Confocal scanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/14—Coupling media or elements to improve sensor contact with skin or tissue
    • A61B2562/146—Coupling media or elements to improve sensor contact with skin or tissue for optical coupling
DE69738527T 1996-05-20 1997-06-30 Konfokales Mikroskop als Handgerät zur Bilderzeugung durch dickes Hautgewebe Expired - Lifetime DE69738527T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/650,684 US5788639A (en) 1995-07-13 1996-05-20 Confocal imaging through thick dermal tissue
PCT/US1997/011472 WO1999000690A1 (en) 1996-05-20 1997-06-30 Confocal imaging through thick dermal tissue

Publications (2)

Publication Number Publication Date
DE69738527D1 true DE69738527D1 (de) 2008-04-03
DE69738527T2 DE69738527T2 (de) 2009-03-26

Family

ID=26792609

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69738527T Expired - Lifetime DE69738527T2 (de) 1996-05-20 1997-06-30 Konfokales Mikroskop als Handgerät zur Bilderzeugung durch dickes Hautgewebe

Country Status (7)

Country Link
US (1) US5788639A (de)
EP (1) EP1002253B1 (de)
JP (1) JP2002509467A (de)
AU (1) AU752872B2 (de)
DE (1) DE69738527T2 (de)
ES (1) ES2299187T3 (de)
WO (1) WO1999000690A1 (de)

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JP2002537579A (ja) 1999-02-17 2002-11-05 ルーシド インコーポレーテッド 組織検体ホルダ
WO2000055669A1 (en) * 1999-03-18 2000-09-21 Lucid, Inc. System and method for enhancing confocal reflectance images of tissue specimens
US6720547B1 (en) * 1999-03-18 2004-04-13 Lucid, Inc. System and method for enhancing confocal reflectance images of tissue specimens
WO2001082786A2 (en) * 2000-05-03 2001-11-08 Flock Stephen T Optical imaging of subsurface anatomical structures and biomolecules
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US7139122B1 (en) 2000-10-17 2006-11-21 Lucid, Inc. System and method for enhancing confocal reflectance images of tissue specimens
US7003345B1 (en) * 2000-10-17 2006-02-21 Lucid, Inc. System and method for enhancing microscope images of tissue using citric acid and agents of the like
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US20040133112A1 (en) * 2002-03-08 2004-07-08 Milind Rajadhyaksha System and method for macroscopic and confocal imaging of tissue
US7158660B2 (en) * 2002-05-08 2007-01-02 Gee Jr James W Method and apparatus for detecting structures of interest
FR2849218B1 (fr) * 2002-12-20 2005-03-04 Mauna Kea Technologies Tete optique confocale, notamment miniature, a balayage integre et systeme d'imagerie confocale mettant en oeuvre ladite tete
ES2594054T3 (es) 2003-05-20 2016-12-15 Lucid, Inc. Microscopio confocal para la formación de imágenes de secciones seleccionadas del cuerpo de un paciente
EP1566617B1 (de) * 2004-02-20 2015-11-11 Carestream Health, Inc. Vorrichtung und Verfahren zur Zahnfarbenbestimmung
EP1607064B1 (de) 2004-06-17 2008-09-03 Cadent Ltd. Verfahren und Gerät zur Farbbildformung einer dreidimensionalen Struktur
US7471450B2 (en) * 2004-10-06 2008-12-30 Northeastern University Confocal reflectance microscope system with dual rotating wedge scanner assembly
EP1895905A4 (de) * 2005-05-12 2014-05-07 Lucid Inc Konfokales abtastmikroskop mit einen in der hand gehaltenen abbildungskopf bereitstellenden optischen abtastsystemen
US7864996B2 (en) * 2006-02-17 2011-01-04 Lucid, Inc. System for macroscopic and confocal imaging of tissue
US8260401B2 (en) 2006-07-26 2012-09-04 University Of Rochester Non-invasive in-vivo imaging of mechanoreceptors in skin using confocal microscopy
US20100063491A1 (en) * 2006-12-12 2010-03-11 Koninklijke Philips Electronics N.V. Device and method for imaging skin objects, and a method and device for reducing hair growth by means thereof
WO2009005748A1 (en) 2007-06-29 2009-01-08 The Trustees Of Columbia University In The City Ofnew York Optical imaging or spectroscopy systems and methods
CN101949839B (zh) * 2010-09-03 2012-10-03 西安工业大学 一种光学表面亚表层损伤测量装置的测量方法
US9795340B2 (en) * 2010-12-13 2017-10-24 National Taiwan University Vacuum-pump sucker
CN104254767B (zh) 2012-02-26 2016-10-26 克力博成像诊断股份有限公司 用于光学切片显微镜的组织样本工作台
BR112015003464B1 (pt) 2012-08-15 2022-01-18 Lucid, Inc Sistemas e processos para formação de imagens de tecido
US9829696B2 (en) * 2013-05-01 2017-11-28 Bio-Rad Laboratories, Inc. Adjustable digital microscope display
WO2015171665A1 (en) 2014-05-05 2015-11-12 Caliber Imaging & Diagnostics, Inc. System and method for mapping the locations of captured confocal images of a lesion in skin tissue
US10514532B1 (en) 2015-09-27 2019-12-24 Caliber Imaging & Diagnostics, Inc. Confocal microscope having a positionable imaging head mounted on a boom stand
US10568695B2 (en) * 2016-09-26 2020-02-25 International Business Machines Corporation Surgical skin lesion removal
US11026581B2 (en) 2016-09-30 2021-06-08 Industrial Technology Research Institute Optical probe for detecting biological tissue
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US10935778B2 (en) 2016-11-12 2021-03-02 Caliber Imaging & Diagnostics, Inc. Confocal microscope with positionable imaging head
EP3351162A1 (de) 2017-01-20 2018-07-25 Universitat Politècnica De Catalunya Computerimplementiertes verfahren, system und computerprogrammprodukte zur charakterisierung einer hautverletzung
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US20210382318A1 (en) * 2020-06-08 2021-12-09 The Regents Of The University Of California White dwarf: cross-polarized white light slide-free imaging
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Also Published As

Publication number Publication date
ES2299187T3 (es) 2008-05-16
WO1999000690A1 (en) 1999-01-07
AU752872B2 (en) 2002-10-03
JP2002509467A (ja) 2002-03-26
DE69738527T2 (de) 2009-03-26
US5788639A (en) 1998-08-04
EP1002253A4 (de) 2002-02-20
EP1002253A1 (de) 2000-05-24
EP1002253B1 (de) 2008-02-20
AU3647297A (en) 1999-01-19

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Legal Events

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