DE69739062D1 - Verwendung von kryptischen Peptiden zur Induktion von immunologischer Toleranz - Google Patents

Verwendung von kryptischen Peptiden zur Induktion von immunologischer Toleranz

Info

Publication number
DE69739062D1
DE69739062D1 DE69739062T DE69739062T DE69739062D1 DE 69739062 D1 DE69739062 D1 DE 69739062D1 DE 69739062 T DE69739062 T DE 69739062T DE 69739062 T DE69739062 T DE 69739062T DE 69739062 D1 DE69739062 D1 DE 69739062D1
Authority
DE
Germany
Prior art keywords
immunological tolerance
induce immunological
cryptic peptides
cryptic
peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69739062T
Other languages
English (en)
Inventor
Anthony Barrington Kay
Mark Larche
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Circassia Ltd
Original Assignee
Circassia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9605904.3A external-priority patent/GB9605904D0/en
Priority claimed from GBGB9608430.6A external-priority patent/GB9608430D0/en
Application filed by Circassia Ltd filed Critical Circassia Ltd
Application granted granted Critical
Publication of DE69739062D1 publication Critical patent/DE69739062D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43531—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE69739062T 1996-03-21 1997-03-20 Verwendung von kryptischen Peptiden zur Induktion von immunologischer Toleranz Expired - Lifetime DE69739062D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9605904.3A GB9605904D0 (en) 1996-03-21 1996-03-21 Peptides
GBGB9608430.6A GB9608430D0 (en) 1996-04-24 1996-04-24 Peptides

Publications (1)

Publication Number Publication Date
DE69739062D1 true DE69739062D1 (de) 2008-12-04

Family

ID=26308965

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69739062T Expired - Lifetime DE69739062D1 (de) 1996-03-21 1997-03-20 Verwendung von kryptischen Peptiden zur Induktion von immunologischer Toleranz
DE69733343T Expired - Lifetime DE69733343D1 (de) 1996-03-21 1997-03-20 Kryptische peptide und verfahren zu ihrer identifizierung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69733343T Expired - Lifetime DE69733343D1 (de) 1996-03-21 1997-03-20 Kryptische peptide und verfahren zu ihrer identifizierung

Country Status (11)

Country Link
US (1) US6737406B1 (de)
EP (2) EP1612555B1 (de)
JP (1) JP4340329B2 (de)
AT (2) ATE412175T1 (de)
AU (1) AU730198C (de)
CA (1) CA2247009C (de)
DE (2) DE69739062D1 (de)
DK (1) DK1612555T3 (de)
ES (1) ES2314515T3 (de)
GB (3) GB2349463B (de)
WO (1) WO1997035193A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2812087B1 (fr) 2000-07-21 2007-05-11 Inst Nat Sante Rech Med Procede de criblage de peptides utilisables en immunotherapie
WO2002066979A1 (fr) * 2001-02-22 2002-08-29 Takara Bio Inc. Procede de detection d'un antigene responsable de l'asthme
PL371675A1 (en) * 2002-06-11 2005-06-27 Merck Patent Gmbh Method for mapping and eliminating t-cell epitopes
GB0710529D0 (en) 2007-06-01 2007-07-11 Circassia Ltd Vaccine
US9340580B2 (en) * 2007-08-15 2016-05-17 Circassia Limited Peptide with multiple epitopes

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2633881B2 (ja) 1986-06-30 1997-07-23 マサチューセッツ インスティテュート オブ テクノロジー 免疫調節組成物及びそれらの使用
US5019384A (en) 1986-06-30 1991-05-28 Massachusetts Institute Of Technology Immunonodulating compositions and their use
US6180368B1 (en) 1988-03-23 2001-01-30 University Of Melbourne Ryegrass pollen allergen
WO1990011293A1 (en) 1989-03-17 1990-10-04 Immulogic Pharmaceutical Corporation Allergenic proteins from ragweed and uses therefor
US5328991A (en) 1989-11-03 1994-07-12 Immulogic Pharmaceutical Corp. Preparation of alkali-modified cat dander allergen (Fel d I) for immunotherapeutic purposes
US5547669A (en) 1989-11-03 1996-08-20 Immulogic Pharma Corp Recombinant peptides comprising T cell epitopes of the cat allergen, Fel d I
US6019972A (en) 1989-11-03 2000-02-01 Immulogic Pharmaceutical Corporation Peptides of human T cell reactive feline protein (TRFP)
CA2073045C (en) * 1989-11-03 2007-05-22 Malcolm L. Gefter A human t cell reactive feline protein (trfp) isolated from house dust and uses therefor
US5433948A (en) 1990-02-13 1995-07-18 Thomas; Wayne R. Cloning and sequencing of allergens of dermatophagoides (house dust mite)
WO1992004445A1 (en) 1990-09-11 1992-03-19 The Western Australian Research Institute For Child Health Ltd. Cloning and sequencing of allergens of dermatophagoides (house dust mite)
AU1272292A (en) 1990-10-30 1992-05-26 Immulogic Pharmaceutical Corporation Peptide binding assays with mhc antigens
WO1992011859A1 (en) 1991-01-08 1992-07-23 Immulogic Pharmaceutical Corporation Peptide-mediated hyposensitization of the human t cell response to dermatophagoides spp. (house dust mite)
EP0595855A1 (de) 1991-07-12 1994-05-11 Immulogic Pharmaceutical Corporation Allergenische proteine und peptide von japanischen zederpollen
WO1994001560A1 (en) 1991-07-12 1994-01-20 Immulogic Pharmaceutical Corporation Allergenic proteins and peptides from japanese cedar pollen
EP0610335B1 (de) * 1991-10-16 2008-01-02 Merck Patent GmbH Verfahren zum Entwurf von Rekombitopen Peptiden
WO1994024281A1 (en) 1993-04-14 1994-10-27 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from dermatophagoides (house dust mite)
HU220462B1 (hu) 1991-10-16 2002-02-28 Immulogic Pharmaceutical Corp. A Dermatophagoides nemzetség allergénjéből származó peptidek, ezeket tartalmazó gyógyszerkészítmények és eljárás házi poratka-érzékenység kimutatására
IL105153A (en) * 1992-03-25 1999-12-22 Immulogic Pharma Corp Therapeutic compositions comprising peptides derived from human t cell reactive feline protein
JPH07507924A (ja) 1992-04-09 1995-09-07 イミュロジック　ファーマスーティカル　コーポレイション アンブロシア・アルテミシフォリア由来の主要アレルゲンのｔ細胞エピトープ
WO1994003478A1 (en) 1992-07-31 1994-02-17 Immulogic Pharmaceutical Corporation Sensitive assay for antigens and antibodies and its use to identify rheumatoid arthritis antigen
CA2148713A1 (en) 1992-11-12 1994-05-26 Mei-Chang Kuo Allergenic proteins and peptides from japanese cedar pollen
ATE318902T1 (de) 1992-12-31 2006-03-15 Immulogic Pharma Corp Allergene proteine und peptide von hundhautanhangsgebilden und ihre verwendung
AU684501B2 (en) 1993-03-12 1997-12-18 Immulogic Pharmaceutical Corporation T cell epitopes of ryegrass pollen allergen
JPH09509135A (ja) * 1993-06-02 1997-09-16 ティーヴィダブリュー テレソン インスティテュート フォー チャイルド ヘルス リサーチ 免疫寛容の誘導における利用のためのクリプティックペプチド
WO1995001597A2 (en) 1993-07-01 1995-01-12 British Telecomm System for generating instructions for speech application
JPH09504167A (ja) 1993-08-13 1997-04-28 イミュロジック ファーマスーティカル コーポレイション ドクムギ花粉アレルゲンのｔ細胞エピトープ
CA2186873A1 (en) 1994-04-01 1995-10-12 Charles J. Hackett Haptenated peptides and uses thereof
KR100379161B1 (ko) 1994-04-14 2003-06-11 이뮤로직 파마시티컬 코포레이션 집먼지진드기에의한알레르기를치료하기위한의학적펩티드조성물
NZ273815A (en) 1994-09-02 1999-05-28 Immulogic Pharma Corp Peptide compositions for treating protein allergies or autoimmune diseases containing at least two isolated and purified peptides
HUT77047A (hu) 1994-10-25 1998-03-02 Immulogic Pharmaceutical Corporation Szklerózis multiplex kezelésére szolgáló készítmények és kezelések
WO1996013589A1 (en) 1994-10-27 1996-05-09 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from ambrosia artemisiifolia
WO1996020950A2 (en) 1995-01-06 1996-07-11 Immulogic Pharmaceutical Corporation Compositions and methods for treating rheumatoid arthritis
DE69738962D1 (de) 1996-03-10 2008-10-16 Meiji Dairies Corp Auf peptiden basierendes immunotherapeutisches mittel gegen allergien
US5804201A (en) 1996-03-11 1998-09-08 The Rockefeller University Immunomodulatory peptides of vespid antigen 5

Also Published As

Publication number Publication date
GB2352518A (en) 2001-01-31
GB2352518B (en) 2001-04-04
CA2247009C (en) 2009-08-04
AU730198C (en) 2002-03-14
CA2247009A1 (en) 1997-09-25
JP4340329B2 (ja) 2009-10-07
GB2326642B (en) 2001-02-07
EP1612555B1 (de) 2008-10-22
DK1612555T3 (da) 2009-02-09
GB2326642A (en) 1998-12-30
EP1612555A1 (de) 2006-01-04
EP0888541B1 (de) 2005-05-25
GB2349463B (en) 2001-01-10
JP2000508627A (ja) 2000-07-11
GB0020260D0 (en) 2000-10-04
WO1997035193A1 (en) 1997-09-25
AU730198B2 (en) 2001-03-01
ES2314515T3 (es) 2009-03-16
EP0888541A1 (de) 1999-01-07
DE69733343D1 (de) 2005-06-30
GB2349463A (en) 2000-11-01
ATE296444T1 (de) 2005-06-15
AU2036597A (en) 1997-10-10
GB0027373D0 (en) 2000-12-27
GB9817461D0 (en) 1998-10-07
US6737406B1 (en) 2004-05-18
ATE412175T1 (de) 2008-11-15

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