DE69740040D1 - Flüssigfeste systeme und verfahren zu deren herstellung - Google Patents

Flüssigfeste systeme und verfahren zu deren herstellung

Info

Publication number
DE69740040D1
DE69740040D1 DE69740040T DE69740040T DE69740040D1 DE 69740040 D1 DE69740040 D1 DE 69740040D1 DE 69740040 T DE69740040 T DE 69740040T DE 69740040 T DE69740040 T DE 69740040T DE 69740040 D1 DE69740040 D1 DE 69740040D1
Authority
DE
Germany
Prior art keywords
coating materials
liquid
carrier
compressible
flowing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69740040T
Other languages
English (en)
Inventor
Spiridon Spireas
Sanford M Bolton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BOLTON, SANFORD M., TUCSON, ARIZ., US
SPIREAS, SPIRIDON, NEW HOPE, PA., US
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24641555&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69740040(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE69740040D1 publication Critical patent/DE69740040D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
DE69740040T 1996-06-10 1997-06-09 Flüssigfeste systeme und verfahren zu deren herstellung Expired - Lifetime DE69740040D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/658,514 US5800834A (en) 1996-06-10 1996-06-10 Liquisolid systems and methods of preparing same
PCT/US1997/010093 WO1997047290A1 (en) 1996-06-10 1997-06-09 Liquisolid systems and methods of preparing same

Publications (1)

Publication Number Publication Date
DE69740040D1 true DE69740040D1 (de) 2010-12-16

Family

ID=24641555

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69740040T Expired - Lifetime DE69740040D1 (de) 1996-06-10 1997-06-09 Flüssigfeste systeme und verfahren zu deren herstellung

Country Status (13)

Country Link
US (2) US5800834A (de)
EP (1) EP0946154B1 (de)
JP (1) JP2000512295A (de)
CN (1) CN1224379C (de)
AT (1) ATE486584T1 (de)
BR (1) BR9709778A (de)
CA (1) CA2257890C (de)
DE (1) DE69740040D1 (de)
ES (1) ES2355871T3 (de)
HK (1) HK1022844A1 (de)
IL (1) IL127295A (de)
RU (1) RU2209623C2 (de)
WO (1) WO1997047290A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2159419C (en) * 1994-10-17 2006-07-04 Pieter De Haan Solid pharmaceutical composition comprising an excipient capable of binding water
EP1104290B1 (de) 1998-08-13 2010-03-31 Cima Labs Inc. Microemulsionen als feste dosisformen zur oralen verabreichung
CA2355860C (en) * 1998-12-23 2010-03-30 Alza Corporation Dosage forms comprising porous particles
US6342249B1 (en) 1998-12-23 2002-01-29 Alza Corporation Controlled release liquid active agent formulation dosage forms
US6635281B2 (en) 1998-12-23 2003-10-21 Alza Corporation Gastric retaining oral liquid dosage form
US6793934B1 (en) 1999-12-08 2004-09-21 Shire Laboratories, Inc. Solid oral dosage form
US7029700B2 (en) * 2000-01-14 2006-04-18 Brown University Research Foundation Micronized freeze-dried particles
US7833549B2 (en) * 2000-01-19 2010-11-16 Mannkind Corporation Dry powder formulations of antihistamine for nasal administration
US6399101B1 (en) 2000-03-30 2002-06-04 Mova Pharmaceutical Corp. Stable thyroid hormone preparations and method of making same
US7056951B2 (en) 2000-09-26 2006-06-06 Mutual Pharmaceutical Co., Inc. Stable solid dosage forms of amino acids and processes for producing same
US6855333B1 (en) 2000-10-03 2005-02-15 Mutual Pharmaceutical Co., Inc. Stabilization of solid thyroid drug formulations
US6979462B1 (en) 2000-10-03 2005-12-27 Mutual Pharmaceutical Co., Inc. Stabilization of solid drug formulations
US6692771B2 (en) 2001-02-23 2004-02-17 Cima Labs Inc. Emulsions as solid dosage forms for oral administration
AU2001241730B2 (en) * 2001-02-23 2007-03-15 Cima Labs Inc. Emulsions as solid dosage forms for oral administration
ITMI20012366A1 (it) * 2001-11-09 2003-05-09 Farmatron Ltd Sistemi terapeutici stabilizzati a rilascio immediato e/o modificato per la somministrazione orale di principi attivi e/o eccipienti e/o ali
US20030099699A1 (en) * 2001-11-13 2003-05-29 Hanshew Dwight D. Storage stable thyroxine active drug formulations and methods for their production
US6645526B2 (en) * 2001-11-13 2003-11-11 Mylan Pharmaceuticals, Inc. Storage stable thyroxine active drug formulations and methods for their production
MXPA05008918A (es) * 2003-02-24 2006-02-17 Pharmaceutical Productions Inc Sistema de administracion transmucosal de farmacos.
US20050181059A1 (en) * 2003-09-30 2005-08-18 Spherics, Inc. Nanoparticulate therapeutic biologically active agents
EP2110124B1 (de) * 2004-03-08 2013-07-17 Spiridon Spireas Bioverfügbare feste Verabreichungsformen von Metaxalon
MY142989A (en) 2004-03-10 2011-02-14 Bayer Schering Pharma Ag Stabilised supersaturated solids of lipophilic drugs
EP1791520A2 (de) * 2004-08-19 2007-06-06 Alza Corporation Darreichungsformen für nanopartikelwirkstoffformulierungen mit kontrollierter freisetzung und verfahren
FR2894822B1 (fr) * 2005-12-20 2011-11-18 Pf Medicament Composition pharmaceutique contenant des acides gras omega-3
US7569612B1 (en) 2006-08-21 2009-08-04 Mutual Pharmaceutical Company, Inc. Methods of use of fenofibric acid
WO2012027222A1 (en) 2010-08-24 2012-03-01 Rutgers, The State University Of New Jersey Formulation and manufacture of pharmaceuticals by impregnation onto porous carriers
CN102949363A (zh) * 2012-11-28 2013-03-06 山东省中医药研究院 熊果酸液固压缩片
CN105102117A (zh) 2013-02-01 2015-11-25 格雷斯公司 作为用于液体技术的载体的多孔硅胶
GB201812022D0 (en) * 2018-07-24 2018-09-05 Univ Of Sussex Pharmaceutical methods and compositions
US10744137B1 (en) * 2020-01-06 2020-08-18 King Abdulaziz University Liquisolid tablet containing combined dose of tadalafil and dapoxetine
CN111067875B (zh) * 2020-01-16 2021-11-30 兰州大学 一种阿苯达唑液固压缩片及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1368112A (en) * 1971-09-08 1974-09-25 Geistlich Soehne Ag Chemical compositions for the treatment of hyperlipemia
DE2400819C2 (de) * 1974-01-09 1982-04-22 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung fester Zubereitungen von schwerlöslichen Arzneimittelwirkstoffen in feinster Verteilung

Also Published As

Publication number Publication date
BR9709778A (pt) 2000-01-11
CA2257890A1 (en) 1997-12-18
EP0946154A1 (de) 1999-10-06
ATE486584T1 (de) 2010-11-15
CN1224379C (zh) 2005-10-26
ES2355871T3 (es) 2011-03-31
US5968550A (en) 1999-10-19
WO1997047290A1 (en) 1997-12-18
CA2257890C (en) 2003-10-28
CN1221337A (zh) 1999-06-30
AU3387097A (en) 1998-01-07
HK1022844A1 (en) 2000-08-25
AU709566B2 (en) 1999-09-02
JP2000512295A (ja) 2000-09-19
IL127295A (en) 2002-05-23
US5800834A (en) 1998-09-01
RU2209623C2 (ru) 2003-08-10
EP0946154A4 (de) 2007-02-07
EP0946154B1 (de) 2010-11-03
IL127295A0 (en) 1999-09-22

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: BOLTON, SANFORD M., TUCSON, ARIZ., US

Owner name: SPIREAS, SPIRIDON, NEW HOPE, PA., US

8381 Inventor (new situation)

Inventor name: SPIREAS, SPIRIDON, NEW HOPE, PA., US

Inventor name: BOLTON, SANFORD M., TUCSON, AZ 85750, US