DE69803729T2 - Mikroteilchen-vergrössertes Streulichtassay und Mikroteilchen-Reagenz dazu - Google Patents
Mikroteilchen-vergrössertes Streulichtassay und Mikroteilchen-Reagenz dazuInfo
- Publication number
- DE69803729T2 DE69803729T2 DE69803729T DE69803729T DE69803729T2 DE 69803729 T2 DE69803729 T2 DE 69803729T2 DE 69803729 T DE69803729 T DE 69803729T DE 69803729 T DE69803729 T DE 69803729T DE 69803729 T2 DE69803729 T2 DE 69803729T2
- Authority
- DE
- Germany
- Prior art keywords
- microparticle
- light scattering
- particles
- scattered light
- scattering properties
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54346—Nanoparticles
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Nanotechnology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97113873 | 1997-08-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69803729D1 DE69803729D1 (de) | 2002-03-21 |
DE69803729T2 true DE69803729T2 (de) | 2002-09-05 |
Family
ID=8227200
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69803729T Expired - Lifetime DE69803729T2 (de) | 1997-08-11 | 1998-08-04 | Mikroteilchen-vergrössertes Streulichtassay und Mikroteilchen-Reagenz dazu |
Country Status (6)
Country | Link |
---|---|
US (2) | US6248597B1 (de) |
JP (1) | JP3746902B2 (de) |
AT (1) | ATE213065T1 (de) |
CA (1) | CA2244326C (de) |
DE (1) | DE69803729T2 (de) |
ES (1) | ES2170984T3 (de) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3510882B2 (ja) * | 2000-06-20 | 2004-03-29 | 三菱レイヨン株式会社 | 生体関連物質マイクロアレイ及びその製造方法 |
US6764825B1 (en) * | 2000-10-13 | 2004-07-20 | Tang J. Wang | Methods and device for detecting prostate specific antigen (PSA) |
AU2002231008A1 (en) * | 2000-12-19 | 2002-07-01 | Instrumentation Laboratory Co. | Free analyte detection system |
US20040091940A1 (en) * | 2001-03-30 | 2004-05-13 | Tokio Sawai | Reagent and method for immunoanalysis of elastase 1 and method of detecting pancreatic disease |
JP4577747B2 (ja) * | 2001-06-05 | 2010-11-10 | 和光純薬工業株式会社 | 免疫学的測定法用凝集促進剤 |
US7790439B2 (en) * | 2001-08-09 | 2010-09-07 | Panasonic Corporation | Biosensor and measurement method |
US6551788B1 (en) * | 2001-11-28 | 2003-04-22 | Beckman Coulter, Inc. | Particle-based ligand assay with extended dynamic range |
CA2523626A1 (en) * | 2002-04-26 | 2003-11-06 | Board Of Regents, The University Of Texas System | Method and system for the detection of cardiac risk factors |
WO2004088317A1 (ja) * | 2003-03-31 | 2004-10-14 | Denka Seiken Co. Ltd. | リポプロテイン(a)の免疫比濁測定法およびその試薬 |
US20040197841A1 (en) * | 2003-04-02 | 2004-10-07 | Apffel James Alexander | Methods and reagents for multiplexed analyses |
DE602004003632T2 (de) * | 2003-07-09 | 2007-10-25 | Matsushita Electric Industrial Co., Ltd., Kadoma | Turbidimetrisches Immuntestverfahren und zugehörige Vorrichtung |
WO2005049653A1 (en) * | 2003-07-14 | 2005-06-02 | Genway Biotech, Inc. | Affinity separation composition and method |
EP1651950A4 (de) * | 2003-08-01 | 2012-01-18 | Ge Healthcare Bio Sciences Ab | Verfahren und vorrichtung zur quantifizierung oberflächenbindender optischer resonanzprofile |
JP4241301B2 (ja) * | 2003-09-30 | 2009-03-18 | 和光純薬工業株式会社 | 免疫学的測定用試薬 |
CA2549190A1 (en) | 2003-12-11 | 2005-06-30 | Board Of Regents, The University Of Texas System | Method and system for the analysis of saliva using a sensor array |
US8101431B2 (en) | 2004-02-27 | 2012-01-24 | Board Of Regents, The University Of Texas System | Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems |
US8105849B2 (en) | 2004-02-27 | 2012-01-31 | Board Of Regents, The University Of Texas System | Integration of fluids and reagents into self-contained cartridges containing sensor elements |
DE102004023402A1 (de) * | 2004-05-12 | 2005-12-08 | Roche Diagnostics Gmbh | Verfahren zur Erhöhung des dynamischen Messbereichs von auf spezifischen Bindereaktionen basierenden, insbesondere immunologischen Testelementen |
JP4331073B2 (ja) * | 2004-08-31 | 2009-09-16 | デンカ生研株式会社 | 抗原の測定方法及びそのための試薬 |
US20060115865A1 (en) * | 2004-10-25 | 2006-06-01 | Anlong Ouyang | Lamotrigine analogs |
US7678551B2 (en) * | 2004-10-25 | 2010-03-16 | Seradyn, Inc. | Immunoassays for lamotrigine |
US7638291B2 (en) | 2004-10-25 | 2009-12-29 | Seradyn, Inc. | Immunoassays for topiramate |
US20060088886A1 (en) * | 2004-10-25 | 2006-04-27 | Anlong Ouyang | Topiramate analogs |
GB0426822D0 (en) * | 2004-12-07 | 2005-01-12 | Precisense As | Sensor for detection of glucose |
US20060246522A1 (en) * | 2005-04-28 | 2006-11-02 | Bhullar Balwant S | C-reactive protein immunoassay and method |
US8377398B2 (en) | 2005-05-31 | 2013-02-19 | The Board Of Regents Of The University Of Texas System | Methods and compositions related to determination and use of white blood cell counts |
EP2508867A1 (de) * | 2005-06-24 | 2012-10-10 | Board Of Regents, The University Of Texas System | Systeme und Verfahren einschliesslich in sich geschlossener Kassetten mit Nachweissystemen und Flüssigkeitszufuhrsystemen |
WO2007024825A2 (en) * | 2005-08-26 | 2007-03-01 | Genway Biotech, Inc. | Immunoaffinity separation and analysis compositions and methods |
PL1952154T3 (pl) * | 2005-11-24 | 2010-10-29 | Gentian As | Turbidymetryczny test immunologiczny do oznaczania stężenia ludzkiej Cystatyny C |
US8158443B2 (en) * | 2007-05-21 | 2012-04-17 | Gentian As | Turbidimetric immunoassay for assessing human Cystatin C |
JP2009085703A (ja) * | 2007-09-28 | 2009-04-23 | Fujifilm Corp | 高感度免疫測定方法 |
WO2010058860A1 (ja) * | 2008-11-18 | 2010-05-27 | 株式会社シノテスト | 試料中のc反応性蛋白質の測定方法及び測定試薬 |
CA2745610C (en) * | 2008-12-04 | 2017-10-31 | Sekisui Medical Co., Ltd. | Method for measuring cystatin c in human body fluid |
EP2241886A1 (de) | 2009-04-15 | 2010-10-20 | Beckman Coulter Biomedical Limited | Homogenes Agglutinationsimmunoassay-Verfahren und Kit für ein derartiges Verfahren |
US9995688B2 (en) * | 2009-09-21 | 2018-06-12 | Arizona Board Of Regents | Use of superhydrophobic surfaces for liquid agglutination assays |
EP2513650A4 (de) | 2009-12-17 | 2013-12-18 | Abay Sa | Neue tests zur detektion von analyten in proben und sowie dazugehörige kits und zusammensetzungen |
CN101833010B (zh) * | 2010-03-29 | 2013-02-13 | 上海太阳生物技术有限公司 | 纤维蛋白(原)降解产物(fdp)测定试剂盒(胶乳免疫比浊法) |
JP5972871B2 (ja) | 2010-07-20 | 2016-08-17 | テバ・ファーマシューティカルズ・オーストラリア・ピーティワイ・リミテッド | 抗il−23ヘテロ二量体特異的抗体 |
US20140106354A1 (en) | 2011-04-18 | 2014-04-17 | Garvan Institute Of Medical Research | Method of Diagnosing Cancer |
CN103597351A (zh) * | 2011-05-23 | 2014-02-19 | 积水医疗株式会社 | 抑制pivka-ii测定试剂中非特异性反应的方法 |
JP5772425B2 (ja) | 2011-09-13 | 2015-09-02 | ソニー株式会社 | 微小粒子測定装置 |
CA2850549C (en) | 2011-09-30 | 2023-03-14 | Teva Pharmaceuticals Australia Pty Ltd. | Antibodies against tl1a and uses thereof |
CA2804843C (en) | 2012-02-06 | 2021-02-02 | Ortho-Clinical Diagnostics, Inc. | Multiple time windows for extending the range of an assay |
CN102608325B (zh) * | 2012-02-24 | 2016-08-24 | 南京诺尔曼生物技术有限公司 | 心型脂肪酸结合蛋白(h-fabp)测定试剂盒(胶乳增强免疫比浊法) |
EP2945942B1 (de) | 2013-01-18 | 2018-05-09 | ARK Diagnostics, Inc. | Voriconazol-immunoassays |
CA2899960C (en) | 2013-02-01 | 2022-05-03 | Transbio Ltd | Anti-cd83 antibodies and use thereof |
US9340618B2 (en) | 2013-02-07 | 2016-05-17 | Csl Limited | IL-11R binding proteins |
US9920136B2 (en) | 2013-02-13 | 2018-03-20 | Ark Diagnostics, Inc. | Posaconazole immunoassays |
FR3003353B1 (fr) * | 2013-03-14 | 2015-03-06 | Horiba Abx Sas | Nouvelle methode de dosage en flux d'un objet d'interet |
JPWO2014192963A1 (ja) | 2013-05-31 | 2017-02-23 | 積水メディカル株式会社 | 免疫凝集測定法 |
EP2811300A1 (de) * | 2013-06-07 | 2014-12-10 | Roche Diagniostics GmbH | Kalibrierung für Mehrkomponenten-Assays |
EP3194624B1 (de) | 2014-09-15 | 2022-02-16 | Garvan Institute of Medical Research | Verfahren zur diagnose, prognose und überwachung von brustkrebs und reagenzien dafür |
US10870704B2 (en) | 2014-10-23 | 2020-12-22 | Kira Biotech Pty Limited | CD83 binding proteins and uses thereof |
EP3761036A1 (de) | 2015-03-03 | 2021-01-06 | ARK Diagnostics, Inc. | Pregabalinimmunoassays |
ES2911266T3 (es) | 2015-05-05 | 2022-05-18 | Mesoblast Int Sarl | Ensayo de potencia |
CA3062112A1 (en) | 2017-05-04 | 2018-11-08 | Mesoblast International Sarl | Mesenchymal lineage precursor or stem cells with enhanced immunosuppression |
CN109633167A (zh) * | 2018-12-20 | 2019-04-16 | 北京贝尔生物工程股份有限公司 | 一种高灵敏度、宽检测范围的人血清淀粉样蛋白a测定试剂盒 |
WO2020141473A1 (en) | 2019-01-02 | 2020-07-09 | Mesoblast International Sárl | Method for treating lower back pain |
US11578140B2 (en) | 2019-03-26 | 2023-02-14 | Microgenics Corporation | Immunoassay for mitragynine |
US10745492B1 (en) | 2019-04-03 | 2020-08-18 | Ark Diagnostics, Inc. | Antibodies to symmetrically dimethylated arginine analytes and use thereof |
CN113125699B (zh) * | 2019-12-31 | 2024-03-26 | 科美博阳诊断技术(上海)有限公司 | 一种β-hCG均相化学发光检测试剂盒及其应用 |
CN115516312A (zh) | 2020-03-30 | 2022-12-23 | 电化株式会社 | 通过胶乳凝集法测定目标物质的方法及其试剂 |
US20230398154A1 (en) | 2020-08-10 | 2023-12-14 | Mesoblast International Sárl | A composition comprising mesenchymal precursor or stem cells and their use |
WO2024009226A1 (en) | 2022-07-05 | 2024-01-11 | Mesoblast International Sarl | Cryopreserved intermediate and potency assay for same |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4210723A (en) | 1976-07-23 | 1980-07-01 | The Dow Chemical Company | Method of coupling a protein to an epoxylated latex |
US4401765A (en) * | 1981-09-01 | 1983-08-30 | E. I. Du Pont De Nemours And Company | Covalently bonded high refractive index particle reagents and their use in light scattering immunoassays |
DE3366740D1 (en) * | 1982-08-06 | 1986-11-13 | Int Inst Cellular Molecul Path | Particle agglutination assay of antigens |
US4590169A (en) | 1983-11-18 | 1986-05-20 | Beckman Instruments, Inc. | Direct particle agglutination immunoassays avoiding false negatives at high antigen concentrations |
US4595661A (en) | 1983-11-18 | 1986-06-17 | Beckman Instruments, Inc. | Immunoassays and kits for use therein which include low affinity antibodies for reducing the hook effect |
NO164622C (no) | 1988-05-11 | 1990-10-24 | Tore Lindmo | Binaer immunometrisk partikkelbasert metode for maaling av spesifikke serum-antigener ved hjelp av vaeskestroemsmikrofotometri og et ferdigpreparert maaloppsett derav. |
US5200315A (en) * | 1990-07-25 | 1993-04-06 | Eastman Kodak Company | Particulate biologically active reagent containing polyoxyalkylene side chains, analytical element and methods for use of the reagent |
-
1998
- 1998-07-29 CA CA002244326A patent/CA2244326C/en not_active Expired - Lifetime
- 1998-08-04 AT AT98114621T patent/ATE213065T1/de not_active IP Right Cessation
- 1998-08-04 DE DE69803729T patent/DE69803729T2/de not_active Expired - Lifetime
- 1998-08-04 ES ES98114621T patent/ES2170984T3/es not_active Expired - Lifetime
- 1998-08-05 US US09/129,744 patent/US6248597B1/en not_active Expired - Lifetime
- 1998-08-10 JP JP22599198A patent/JP3746902B2/ja not_active Expired - Lifetime
-
2001
- 2001-04-06 US US09/827,846 patent/US6828158B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2244326C (en) | 2006-03-28 |
ES2170984T3 (es) | 2002-08-16 |
US6248597B1 (en) | 2001-06-19 |
ATE213065T1 (de) | 2002-02-15 |
JPH11108929A (ja) | 1999-04-23 |
CA2244326A1 (en) | 1999-02-11 |
US6828158B2 (en) | 2004-12-07 |
DE69803729D1 (de) | 2002-03-21 |
JP3746902B2 (ja) | 2006-02-22 |
US20010026945A1 (en) | 2001-10-04 |
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