DE69803729T2 - Mikroteilchen-vergrössertes Streulichtassay und Mikroteilchen-Reagenz dazu - Google Patents
Mikroteilchen-vergrössertes Streulichtassay und Mikroteilchen-Reagenz dazuInfo
- Publication number
- DE69803729T2 DE69803729T2 DE69803729T DE69803729T DE69803729T2 DE 69803729 T2 DE69803729 T2 DE 69803729T2 DE 69803729 T DE69803729 T DE 69803729T DE 69803729 T DE69803729 T DE 69803729T DE 69803729 T2 DE69803729 T2 DE 69803729T2
- Authority
- DE
- Germany
- Prior art keywords
- microparticle
- light scattering
- particles
- scattered light
- scattering properties
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54346—Nanoparticles
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97113873 | 1997-08-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69803729D1 DE69803729D1 (de) | 2002-03-21 |
DE69803729T2 true DE69803729T2 (de) | 2002-09-05 |
Family
ID=8227200
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69803729T Expired - Lifetime DE69803729T2 (de) | 1997-08-11 | 1998-08-04 | Mikroteilchen-vergrössertes Streulichtassay und Mikroteilchen-Reagenz dazu |
Country Status (6)
Country | Link |
---|---|
US (2) | US6248597B1 (de) |
JP (1) | JP3746902B2 (de) |
AT (1) | ATE213065T1 (de) |
CA (1) | CA2244326C (de) |
DE (1) | DE69803729T2 (de) |
ES (1) | ES2170984T3 (de) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7718438B2 (en) * | 2000-06-20 | 2010-05-18 | Mitsubishi Rayon Co., Ltd. | Method for producing a microarray |
US6764825B1 (en) * | 2000-10-13 | 2004-07-20 | Tang J. Wang | Methods and device for detecting prostate specific antigen (PSA) |
WO2002050543A2 (en) * | 2000-12-19 | 2002-06-27 | Instrumentation Laboratory Co. | Free analyte detection system |
JPWO2002079782A1 (ja) * | 2001-03-30 | 2004-07-22 | 株式会社三菱化学ヤトロン | エラスターゼ1の免疫分析用試薬及び免疫分析方法並びに膵疾患の検出方法 |
JP4577747B2 (ja) * | 2001-06-05 | 2010-11-10 | 和光純薬工業株式会社 | 免疫学的測定法用凝集促進剤 |
DE60218695T2 (de) * | 2001-08-09 | 2007-11-15 | Matsushita Electric Industrial Co., Ltd., Kadoma | Biosensoren und messverfahren |
US6551788B1 (en) * | 2001-11-28 | 2003-04-22 | Beckman Coulter, Inc. | Particle-based ligand assay with extended dynamic range |
AU2003228711C1 (en) * | 2002-04-26 | 2010-01-07 | Board Of Regents, The University Of Texas System | Method and system for the detection of cardiac risk factors |
US20060257926A1 (en) * | 2003-03-31 | 2006-11-16 | Tadashi Yamazaki | Immuno-nephelometry of lipoprotein (a) and reagent therefor |
US20040197841A1 (en) * | 2003-04-02 | 2004-10-07 | Apffel James Alexander | Methods and reagents for multiplexed analyses |
EP1496362B1 (de) * | 2003-07-09 | 2006-12-13 | Matsushita Electric Industrial Co., Ltd. | Turbidimetrisches Immuntestverfahren und zugehörige Vorrichtung |
WO2005049653A1 (en) * | 2003-07-14 | 2005-06-02 | Genway Biotech, Inc. | Affinity separation composition and method |
US7822568B2 (en) * | 2003-08-01 | 2010-10-26 | Ge Healthcare Bio-Sciences Ab | Method and apparatus for quantitating surface-binding optical resonance profiles |
JP4241301B2 (ja) * | 2003-09-30 | 2009-03-18 | 和光純薬工業株式会社 | 免疫学的測定用試薬 |
US7651868B2 (en) | 2003-12-11 | 2010-01-26 | The Board Of Regents Of The University Of Texas System | Method and system for the analysis of saliva using a sensor array |
US8105849B2 (en) | 2004-02-27 | 2012-01-31 | Board Of Regents, The University Of Texas System | Integration of fluids and reagents into self-contained cartridges containing sensor elements |
US8101431B2 (en) | 2004-02-27 | 2012-01-24 | Board Of Regents, The University Of Texas System | Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems |
DE102004023402A1 (de) | 2004-05-12 | 2005-12-08 | Roche Diagnostics Gmbh | Verfahren zur Erhöhung des dynamischen Messbereichs von auf spezifischen Bindereaktionen basierenden, insbesondere immunologischen Testelementen |
JP4331073B2 (ja) * | 2004-08-31 | 2009-09-16 | デンカ生研株式会社 | 抗原の測定方法及びそのための試薬 |
US20060088886A1 (en) * | 2004-10-25 | 2006-04-27 | Anlong Ouyang | Topiramate analogs |
US7678551B2 (en) * | 2004-10-25 | 2010-03-16 | Seradyn, Inc. | Immunoassays for lamotrigine |
US7638291B2 (en) | 2004-10-25 | 2009-12-29 | Seradyn, Inc. | Immunoassays for topiramate |
US20060115865A1 (en) * | 2004-10-25 | 2006-06-01 | Anlong Ouyang | Lamotrigine analogs |
GB0426822D0 (en) * | 2004-12-07 | 2005-01-12 | Precisense As | Sensor for detection of glucose |
US20060246522A1 (en) * | 2005-04-28 | 2006-11-02 | Bhullar Balwant S | C-reactive protein immunoassay and method |
US8377398B2 (en) | 2005-05-31 | 2013-02-19 | The Board Of Regents Of The University Of Texas System | Methods and compositions related to determination and use of white blood cell counts |
CA2613078A1 (en) * | 2005-06-24 | 2007-01-04 | Board Of Regents, The University Of Texas System | Systems and methods including self-contained cartridges with detection systems and fluid delivery systems |
US20070048795A1 (en) * | 2005-08-26 | 2007-03-01 | Xiangming Fang | Immunoaffinity separation and analysis compositions and methods |
WO2007102054A2 (en) * | 2005-11-24 | 2007-09-13 | Gentian As | Turbidimetric immunoassay for assessing human cystatin c |
WO2008142057A1 (en) * | 2007-05-21 | 2008-11-27 | Gentian As | Turbidimetric immunoassay for assessing human cystatin c |
JP2009085703A (ja) * | 2007-09-28 | 2009-04-23 | Fujifilm Corp | 高感度免疫測定方法 |
JP5807300B2 (ja) * | 2008-11-18 | 2015-11-10 | 株式会社シノテスト | 試料中のc反応性蛋白質の測定方法及び測定試薬 |
US8802446B2 (en) | 2008-12-04 | 2014-08-12 | Sekisui Medical Co., Ltd. | Method for measuring cystatin C in human body fluid |
EP2241886A1 (de) | 2009-04-15 | 2010-10-20 | Beckman Coulter Biomedical Limited | Homogenes Agglutinationsimmunoassay-Verfahren und Kit für ein derartiges Verfahren |
US9995688B2 (en) * | 2009-09-21 | 2018-06-12 | Arizona Board Of Regents | Use of superhydrophobic surfaces for liquid agglutination assays |
EP2513650A4 (de) | 2009-12-17 | 2013-12-18 | Abay Sa | Neue tests zur detektion von analyten in proben und sowie dazugehörige kits und zusammensetzungen |
CN101833010B (zh) * | 2010-03-29 | 2013-02-13 | 上海太阳生物技术有限公司 | 纤维蛋白(原)降解产物(fdp)测定试剂盒(胶乳免疫比浊法) |
NZ604415A (en) | 2010-07-20 | 2014-10-31 | Cephalon Australia Pty Ltd | Anti-il-23 heterodimer specific antibodies |
US20140106354A1 (en) | 2011-04-18 | 2014-04-17 | Garvan Institute Of Medical Research | Method of Diagnosing Cancer |
JP6016789B2 (ja) * | 2011-05-23 | 2016-10-26 | 積水メディカル株式会社 | Pivka−ii測定試薬における非特異反応の抑制方法 |
JP5772425B2 (ja) | 2011-09-13 | 2015-09-02 | ソニー株式会社 | 微小粒子測定装置 |
EA035018B1 (ru) | 2011-09-30 | 2020-04-17 | Тева Фармасьютикал Австралия Пти Лтд. | АНТИТЕЛА К TL1a И ИХ ПРИМЕНЕНИЕ |
CA2804843C (en) | 2012-02-06 | 2021-02-02 | Ortho-Clinical Diagnostics, Inc. | Multiple time windows for extending the range of an assay |
CN102608325B (zh) * | 2012-02-24 | 2016-08-24 | 南京诺尔曼生物技术有限公司 | 心型脂肪酸结合蛋白(h-fabp)测定试剂盒(胶乳增强免疫比浊法) |
EP2945942B1 (de) | 2013-01-18 | 2018-05-09 | ARK Diagnostics, Inc. | Voriconazol-immunoassays |
CA2899960C (en) | 2013-02-01 | 2022-05-03 | Transbio Ltd | Anti-cd83 antibodies and use thereof |
EP4219552A3 (de) | 2013-02-07 | 2023-09-13 | CSL Ltd. | Il-11r-bindende proteine und verwendungen davon |
WO2014126861A1 (en) | 2013-02-13 | 2014-08-21 | Ark Diagnostics, Inc. | Posaconazole immunoassays |
FR3003353B1 (fr) * | 2013-03-14 | 2015-03-06 | Horiba Abx Sas | Nouvelle methode de dosage en flux d'un objet d'interet |
US20160195522A1 (en) | 2013-05-31 | 2016-07-07 | Sekisui Medical Co., Ltd. | Method of agglutination immunoassay |
EP2811300A1 (de) * | 2013-06-07 | 2014-12-10 | Roche Diagniostics GmbH | Kalibrierung für Mehrkomponenten-Assays |
AU2015318823A1 (en) | 2014-09-15 | 2016-03-24 | Garvan Institute Of Medical Research | Methods for diagnosis, prognosis and monitoring of breast cancer and reagents therefor |
NZ731491A (en) | 2014-10-23 | 2021-12-24 | Kira Biotech Pty Ltd | Cd83 binding proteins and uses thereof |
WO2016140799A1 (en) | 2015-03-03 | 2016-09-09 | Ark Diagnostics, Inc. | Pregabalin immunoassays |
CN107771220B (zh) | 2015-05-05 | 2022-07-05 | 迈索布拉斯特国际有限公司 | 效能分析 |
CA3062112A1 (en) | 2017-05-04 | 2018-11-08 | Mesoblast International Sarl | Mesenchymal lineage precursor or stem cells with enhanced immunosuppression |
CN109633167A (zh) * | 2018-12-20 | 2019-04-16 | 北京贝尔生物工程股份有限公司 | 一种高灵敏度、宽检测范围的人血清淀粉样蛋白a测定试剂盒 |
US20220143097A1 (en) | 2019-01-02 | 2022-05-12 | Mesoblast International Sárl | Method for treating lower back pain |
US11578140B2 (en) | 2019-03-26 | 2023-02-14 | Microgenics Corporation | Immunoassay for mitragynine |
US10745492B1 (en) | 2019-04-03 | 2020-08-18 | Ark Diagnostics, Inc. | Antibodies to symmetrically dimethylated arginine analytes and use thereof |
CN113125699B (zh) * | 2019-12-31 | 2024-03-26 | 科美博阳诊断技术(上海)有限公司 | 一种β-hCG均相化学发光检测试剂盒及其应用 |
CN115516312A (zh) | 2020-03-30 | 2022-12-23 | 电化株式会社 | 通过胶乳凝集法测定目标物质的方法及其试剂 |
JP2023537102A (ja) | 2020-08-10 | 2023-08-30 | メゾブラスト・インターナショナル・エスアーエールエル | 間葉系前駆体又は幹細胞及びそれらの使用を含む組成物 |
WO2024009226A1 (en) | 2022-07-05 | 2024-01-11 | Mesoblast International Sarl | Cryopreserved intermediate and potency assay for same |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4210723A (en) | 1976-07-23 | 1980-07-01 | The Dow Chemical Company | Method of coupling a protein to an epoxylated latex |
US4401765A (en) * | 1981-09-01 | 1983-08-30 | E. I. Du Pont De Nemours And Company | Covalently bonded high refractive index particle reagents and their use in light scattering immunoassays |
EP0101228B1 (de) * | 1982-08-06 | 1986-10-08 | International Institute Of Cellular And Molecular Pathology (Icp) | Bestimmung von Antigenen durch Teilchenagglutination |
US4595661A (en) | 1983-11-18 | 1986-06-17 | Beckman Instruments, Inc. | Immunoassays and kits for use therein which include low affinity antibodies for reducing the hook effect |
US4590169A (en) | 1983-11-18 | 1986-05-20 | Beckman Instruments, Inc. | Direct particle agglutination immunoassays avoiding false negatives at high antigen concentrations |
NO164622C (no) | 1988-05-11 | 1990-10-24 | Tore Lindmo | Binaer immunometrisk partikkelbasert metode for maaling av spesifikke serum-antigener ved hjelp av vaeskestroemsmikrofotometri og et ferdigpreparert maaloppsett derav. |
US5200315A (en) * | 1990-07-25 | 1993-04-06 | Eastman Kodak Company | Particulate biologically active reagent containing polyoxyalkylene side chains, analytical element and methods for use of the reagent |
-
1998
- 1998-07-29 CA CA002244326A patent/CA2244326C/en not_active Expired - Lifetime
- 1998-08-04 AT AT98114621T patent/ATE213065T1/de not_active IP Right Cessation
- 1998-08-04 ES ES98114621T patent/ES2170984T3/es not_active Expired - Lifetime
- 1998-08-04 DE DE69803729T patent/DE69803729T2/de not_active Expired - Lifetime
- 1998-08-05 US US09/129,744 patent/US6248597B1/en not_active Expired - Lifetime
- 1998-08-10 JP JP22599198A patent/JP3746902B2/ja not_active Expired - Lifetime
-
2001
- 2001-04-06 US US09/827,846 patent/US6828158B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US6828158B2 (en) | 2004-12-07 |
JP3746902B2 (ja) | 2006-02-22 |
US6248597B1 (en) | 2001-06-19 |
JPH11108929A (ja) | 1999-04-23 |
DE69803729D1 (de) | 2002-03-21 |
ATE213065T1 (de) | 2002-02-15 |
CA2244326A1 (en) | 1999-02-11 |
ES2170984T3 (es) | 2002-08-16 |
CA2244326C (en) | 2006-03-28 |
US20010026945A1 (en) | 2001-10-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69803729T2 (de) | Mikroteilchen-vergrössertes Streulichtassay und Mikroteilchen-Reagenz dazu | |
EP0898169A3 (de) | Mikroteilchen-vergrössertes Streulichtassay und Mikroteilchen-Reagenz dazu | |
AU2002232518A1 (en) | Improved assay and reagents or immunological determination of analyte concentration | |
WO2005065387A3 (en) | Waveguide comprising scattered light detectable particles | |
AU5665696A (en) | Novel methods for the assay of troponin i and t and complexe s of troponin i and t and selection of antibodies for use in immunoassays | |
EP2186910A3 (de) | Verfahren und Zusammensetzungen für verbesserte Lumineszenztests unter Verwendung von Mikropartikeln | |
HK1052217A1 (zh) | 用於被分析物濃度測定試驗的方法及裝置 | |
CA2215042A1 (en) | Assay reagents and devices | |
DE60013320D1 (de) | Analytassay-vorrichtung mit vorabsorbieren-zone | |
WO2002029410A3 (en) | Cells having a spectral signature, and methods of preparation and use thereof | |
WO2002042427A3 (en) | Mass tags for quantitative analysis | |
ATE201771T1 (de) | Spezifische bindungstests und reagenzien dafür | |
BRPI0114343B8 (pt) | método para detecção de imunoglobulina ige e para diagnóstico in vitro de alergias, bem como chip de microarranjo e kit que o compreende | |
HK1008244A1 (en) | Use of synthetic particles as reagents in agglutination reactions | |
AU3059499A (en) | Solid-phase method for antigen and antibody determinations in bloodgroup serology, and test kit | |
AU5141301A (en) | Multi-analyte diagnostic test for thyroid disorders | |
EP1038939A4 (de) | Chemilumineszierende realenzien und verfahren zur chemilumineszenzanalyse | |
MXPA05009835A (es) | Reduccion de efecto de gancho en dispositivos de ensayo. | |
DE69526875T2 (de) | Suppressor von nichtspezifischen Reaktionen in Immuno-Assays | |
SE8307004D0 (sv) | Substrat for fluoroimmunoanalys av biologiska vetskor | |
ATE182407T1 (de) | Bestimmung von denaturierten lipoproteinen | |
AU2002245206A1 (en) | Dendritic chemiluminescent substrates | |
ATE170927T1 (de) | Ionenfang-analysenverfahren, die einen an carboxymethylamylose konjugierten bindungspartner verwenden | |
SE9500184D0 (sv) | Analysmetod som utnyttjar biospecifika affinitetsreaktioner och märkt reaktant samt reagens att användas i föredragen utförandeform | |
EP1304571A4 (de) | Immunoassay unter verwendung von unlöslichen trägerpartikeln und reagenz hierfür |