DE69807746D1 - Mehrschichtige durchfluss-kontrollierende membranen zur verwendung in einer elektrotransportvorrichtung - Google Patents
Mehrschichtige durchfluss-kontrollierende membranen zur verwendung in einer elektrotransportvorrichtungInfo
- Publication number
- DE69807746D1 DE69807746D1 DE69807746T DE69807746T DE69807746D1 DE 69807746 D1 DE69807746 D1 DE 69807746D1 DE 69807746 T DE69807746 T DE 69807746T DE 69807746 T DE69807746 T DE 69807746T DE 69807746 D1 DE69807746 D1 DE 69807746D1
- Authority
- DE
- Germany
- Prior art keywords
- transport device
- membrane
- layer flow
- electric transport
- controlling membranes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000012528 membrane Substances 0.000 title abstract 7
- 239000003814 drug Substances 0.000 abstract 3
- 229940079593 drug Drugs 0.000 abstract 2
- 230000004907 flux Effects 0.000 abstract 2
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0444—Membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0448—Drug reservoir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0432—Anode and cathode
- A61N1/0436—Material of the electrode
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6804797P | 1997-12-18 | 1997-12-18 | |
PCT/US1998/026612 WO1999030774A1 (en) | 1997-12-18 | 1998-12-14 | Layered rate controlling membranes for use in an electrotransport device |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69807746D1 true DE69807746D1 (de) | 2002-10-10 |
DE69807746T2 DE69807746T2 (de) | 2003-01-02 |
Family
ID=22080088
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69807746T Expired - Lifetime DE69807746T2 (de) | 1997-12-18 | 1998-12-14 | Mehrschichtige durchfluss-kontrollierende membranen zur verwendung in einer elektrotransportvorrichtung |
Country Status (11)
Country | Link |
---|---|
US (1) | US6163720A (de) |
EP (1) | EP1039949B1 (de) |
JP (2) | JP4038019B2 (de) |
KR (1) | KR100584630B1 (de) |
CN (1) | CN1282262A (de) |
AT (1) | ATE223244T1 (de) |
AU (1) | AU1827599A (de) |
CA (1) | CA2315228C (de) |
DE (1) | DE69807746T2 (de) |
ES (1) | ES2181315T3 (de) |
WO (1) | WO1999030774A1 (de) |
Families Citing this family (35)
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US7070590B1 (en) | 1996-07-02 | 2006-07-04 | Massachusetts Institute Of Technology | Microchip drug delivery devices |
US6491666B1 (en) | 1999-11-17 | 2002-12-10 | Microchips, Inc. | Microfabricated devices for the delivery of molecules into a carrier fluid |
AU782639B2 (en) * | 1999-12-10 | 2005-08-18 | Massachusetts Institute Of Technology | Microchip devices for delivery of molecules and methods of fabrication thereof |
WO2001064344A2 (en) * | 2000-03-02 | 2001-09-07 | Microchips, Inc. | Microfabricated devices for the storage and selective exposure of chemicals and devices |
JP4657577B2 (ja) * | 2001-01-09 | 2011-03-23 | マイクロチップス・インコーポレーテッド | 眼への適用および他への適用のための可撓性マイクロチップデバイス |
DE10141650C1 (de) | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
AU2007203024B2 (en) * | 2001-12-19 | 2008-11-13 | Alza Corporation | Reservoir housing having a conductive region integrally formed therein |
ES2321173T3 (es) * | 2001-12-19 | 2009-06-03 | Alza Corporation | Carcasa de deposito que contiene una zona conductora formada de manera integrada en el interior. |
US20060116663A1 (en) * | 2002-05-01 | 2006-06-01 | Joshi Ashok V | Electro-osmotic fluid delivery device and method |
US7458965B2 (en) * | 2002-05-01 | 2008-12-02 | Microlin, Llc | Fluid delivery device having an electrochemical pump with an ion-exchange membrane and associated method |
US7896867B2 (en) * | 2002-05-01 | 2011-03-01 | Microlin, Llc | Fluid delivery device having an electrochemical pump with an ion-exchange membrane and associated method |
US7470267B2 (en) * | 2002-05-01 | 2008-12-30 | Microlin, Llc | Fluid delivery device having an electrochemical pump with an anionic exchange membrane and associated method |
US7591801B2 (en) | 2004-02-26 | 2009-09-22 | Dexcom, Inc. | Integrated delivery device for continuous glucose sensor |
US8808228B2 (en) | 2004-02-26 | 2014-08-19 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor |
US7413846B2 (en) * | 2004-11-15 | 2008-08-19 | Microchips, Inc. | Fabrication methods and structures for micro-reservoir devices |
WO2006072834A2 (en) * | 2004-11-29 | 2006-07-13 | Power Paper Ltd. | Stable electrode and uses thereof |
JP4728631B2 (ja) * | 2004-11-30 | 2011-07-20 | Tti・エルビュー株式会社 | イオントフォレーシス装置 |
WO2006081279A2 (en) | 2005-01-25 | 2006-08-03 | Microchips, Inc. | Control of drug release by transient modification of local microenvironments |
US20070027426A1 (en) * | 2005-06-24 | 2007-02-01 | Transcutaneous Technologies Inc. | Iontophoresis device to deliver active agents to biological interfaces |
US8348930B2 (en) * | 2005-07-01 | 2013-01-08 | Microlin, Llc | Fluid delivery device with a diffusion membrane and electrochemical pump |
US20070021735A1 (en) * | 2005-07-15 | 2007-01-25 | Sai Bhavaraju | Dual membrane electro-osmotic fluid delivery device |
US8386030B2 (en) | 2005-08-08 | 2013-02-26 | Tti Ellebeau, Inc. | Iontophoresis device |
JPWO2007026671A1 (ja) * | 2005-08-29 | 2009-03-05 | Tti・エルビュー株式会社 | センサからの情報により投与すべき薬剤の選定を行うイオントフォレーシス装置 |
JP4804904B2 (ja) * | 2005-12-09 | 2011-11-02 | Tti・エルビュー株式会社 | イオントフォレーシス装置包装品 |
US20080004671A1 (en) * | 2006-06-28 | 2008-01-03 | Alza Corporation | Vagus nerve stimulation via orally delivered apparatus |
US20080009782A1 (en) * | 2006-06-28 | 2008-01-10 | Alza Corporation | Methods and Devices for Transdermal Electrotransport Delivery of Lofentanil and Carfentanil |
JP5383497B2 (ja) * | 2006-12-01 | 2014-01-08 | Tti・エルビュー株式会社 | 装置、例として経皮送達装置に給電し且つ/又は当該装置を制御するシステム及び装置 |
US8197844B2 (en) | 2007-06-08 | 2012-06-12 | Activatek, Inc. | Active electrode for transdermal medicament administration |
WO2008154312A1 (en) | 2007-06-08 | 2008-12-18 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor |
US9452258B2 (en) | 2007-10-09 | 2016-09-27 | Dexcom, Inc. | Integrated insulin delivery system with continuous glucose sensor |
US8862223B2 (en) | 2008-01-18 | 2014-10-14 | Activatek, Inc. | Active transdermal medicament patch and circuit board for same |
KR101286272B1 (ko) * | 2011-07-20 | 2013-07-15 | (재)예수병원유지재단 | 피복재 및 전기자극기가 구비된 의료기기 |
CA2910596C (en) | 2013-07-19 | 2021-07-20 | Dexcom, Inc. | Time averaged basal rate optimizer |
US20190120785A1 (en) | 2017-10-24 | 2019-04-25 | Dexcom, Inc. | Pre-connected analyte sensors |
US11331022B2 (en) | 2017-10-24 | 2022-05-17 | Dexcom, Inc. | Pre-connected analyte sensors |
Family Cites Families (41)
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US3797494A (en) * | 1969-04-01 | 1974-03-19 | Alza Corp | Bandage for the administration of drug by controlled metering through microporous materials |
US4156066A (en) * | 1977-06-23 | 1979-05-22 | Tyndale Plains - Hunter Ltd. | Polyurethane polymers characterized by lactone groups and hydroxyl groups in the polymer backbone |
SU648232A1 (ru) * | 1977-11-21 | 1979-02-25 | Свердловский Научно-Исследовательский Институт Курортологии И Физиотерапии | Электрод дл электрофореза |
US4250878A (en) * | 1978-11-22 | 1981-02-17 | Motion Control, Inc. | Non-invasive chemical species delivery apparatus and method |
CA1153427A (en) * | 1978-12-11 | 1983-09-06 | Patrick T. Cahalan | Tape electrode |
US4416274A (en) * | 1981-02-23 | 1983-11-22 | Motion Control, Inc. | Ion mobility limiting iontophoretic bioelectrode |
JPS5810066A (ja) * | 1981-07-10 | 1983-01-20 | 株式会社アドバンス | イオントフオレ−ゼ用プラスタ−構造体 |
US4419092A (en) * | 1981-11-06 | 1983-12-06 | Motion Control, Inc. | Iontophoretic electrode structure |
US4526176A (en) * | 1981-12-22 | 1985-07-02 | Frantz Medical Development Ltd. | Long-life biomedical application device, particularly electrode, and method of transferring electrical current |
US4639244A (en) * | 1983-05-03 | 1987-01-27 | Nabil I. Rizk | Implantable electrophoretic pump for ionic drugs and associated methods |
US4557723A (en) * | 1983-08-18 | 1985-12-10 | Drug Delivery Systems Inc. | Applicator for the non-invasive transcutaneous delivery of medicament |
US4883457A (en) * | 1983-08-18 | 1989-11-28 | Drug Delivery Systems Inc. | Disposable and/or replenishable transdermal drug applicators and methods of manufacturing same |
US4919648A (en) * | 1983-08-18 | 1990-04-24 | Drug Delivery Systems Inc. | High tack drug patch |
US4640689A (en) * | 1983-08-18 | 1987-02-03 | Drug Delivery Systems Inc. | Transdermal drug applicator and electrodes therefor |
US4537680A (en) * | 1984-06-04 | 1985-08-27 | The Board Of Trustees Of The Leland Stanford Junior University | Integral fluid filter and capillary |
GB8422876D0 (en) * | 1984-09-11 | 1984-10-17 | Secr Defence | Silicon implant devices |
US4702732A (en) * | 1984-12-24 | 1987-10-27 | Trustees Of Boston University | Electrodes, electrode assemblies, methods, and systems for tissue stimulation and transdermal delivery of pharmacologically active ligands |
GB8509978D0 (en) * | 1985-04-18 | 1985-05-30 | Juhasz L | Wound dressings |
US4886514A (en) * | 1985-05-02 | 1989-12-12 | Ivac Corporation | Electrochemically driven drug dispenser |
US4904475A (en) * | 1985-05-03 | 1990-02-27 | Alza Corporation | Transdermal delivery of drugs from an aqueous reservoir |
US4710191A (en) * | 1985-12-16 | 1987-12-01 | Jonergin, Inc. | Therapeutic device for the administration of medicaments |
US4722726A (en) * | 1986-02-12 | 1988-02-02 | Key Pharmaceuticals, Inc. | Method and apparatus for iontophoretic drug delivery |
US4786277A (en) * | 1986-11-21 | 1988-11-22 | Trustees Of Boston University | Electrodes, electrode assemblies, methods, and systems for tissue stimulation |
EP0273167A1 (de) * | 1986-11-26 | 1988-07-06 | Siemens Aktiengesellschaft | Leitfähige Zwischenlage für Elektroden |
US4731049A (en) * | 1987-01-30 | 1988-03-15 | Ionics, Incorporated | Cell for electrically controlled transdermal drug delivery |
US4878892A (en) * | 1987-02-10 | 1989-11-07 | Drug Delivery Systems Inc. | Electrolytic transdermal delivery of polypeptides |
US5080646A (en) * | 1988-10-03 | 1992-01-14 | Alza Corporation | Membrane for electrotransport transdermal drug delivery |
US4935345A (en) * | 1987-04-07 | 1990-06-19 | Arizona Board Of Regents | Implantable microelectronic biochemical sensor incorporating thin film thermopile |
US4931046A (en) * | 1987-05-15 | 1990-06-05 | Newman Martin H | Iontophoresis drug delivery system |
US4942883A (en) * | 1987-09-29 | 1990-07-24 | Newman Martin H | Drug delivery device |
US4959208A (en) * | 1987-10-19 | 1990-09-25 | Ppg Industries, Inc. | Active agent delivery device |
JP2594812B2 (ja) * | 1988-04-15 | 1997-03-26 | 日東電工株式会社 | 導電性部材と多孔質部材との導電性接着物の製造方法 |
US4927408A (en) * | 1988-10-03 | 1990-05-22 | Alza Corporation | Electrotransport transdermal system |
US5169382A (en) * | 1988-10-03 | 1992-12-08 | Alza Corporation | Membrane for electrotransport transdermal drug delivery |
DK0521988T3 (da) * | 1990-03-30 | 1996-04-29 | Alza Corp | Anordning til iontoforetisk lægemiddeltilførsel |
US5443727A (en) * | 1990-10-30 | 1995-08-22 | Minnesota Mining And Manufacturing Company | Articles having a polymeric shell and method for preparing same |
US5900250A (en) * | 1992-05-13 | 1999-05-04 | Alza Corporation | Monoglyceride/lactate ester permeation enhancer for oxybutnin |
US5681568A (en) * | 1994-08-19 | 1997-10-28 | Cambridge Neuroscience, Inc. | Device for delivery of substances and methods of use thereof |
US5894021A (en) * | 1994-09-30 | 1999-04-13 | Kabushiki Kaisya Advance | Iontophoretic transdermal drug-delivery interface and skin treatment agent and treatment method using the same |
ATE248004T1 (de) * | 1995-06-14 | 2003-09-15 | Hisamitsu Pharmaceutical Co | Schnittstelle für iontophorese |
WO1997012644A1 (en) * | 1995-09-29 | 1997-04-10 | Becton Dickinson And Company | Improved iontophoretic reservoir apparatus |
-
1998
- 1998-12-03 US US09/204,820 patent/US6163720A/en not_active Expired - Lifetime
- 1998-12-14 AU AU18275/99A patent/AU1827599A/en not_active Abandoned
- 1998-12-14 ES ES98963197T patent/ES2181315T3/es not_active Expired - Lifetime
- 1998-12-14 JP JP2000538749A patent/JP4038019B2/ja not_active Expired - Fee Related
- 1998-12-14 AT AT98963197T patent/ATE223244T1/de not_active IP Right Cessation
- 1998-12-14 EP EP98963197A patent/EP1039949B1/de not_active Expired - Lifetime
- 1998-12-14 CA CA002315228A patent/CA2315228C/en not_active Expired - Fee Related
- 1998-12-14 CN CN98812304A patent/CN1282262A/zh active Pending
- 1998-12-14 DE DE69807746T patent/DE69807746T2/de not_active Expired - Lifetime
- 1998-12-14 KR KR1020007006591A patent/KR100584630B1/ko not_active IP Right Cessation
- 1998-12-14 WO PCT/US1998/026612 patent/WO1999030774A1/en active IP Right Grant
-
2007
- 2007-06-19 JP JP2007161218A patent/JP4139844B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO1999030774A1 (en) | 1999-06-24 |
CA2315228C (en) | 2007-09-18 |
KR100584630B1 (ko) | 2006-05-30 |
US6163720A (en) | 2000-12-19 |
EP1039949B1 (de) | 2002-09-04 |
AU1827599A (en) | 1999-07-05 |
CN1282262A (zh) | 2001-01-31 |
JP2002508229A (ja) | 2002-03-19 |
JP4038019B2 (ja) | 2008-01-23 |
EP1039949A1 (de) | 2000-10-04 |
JP2007283118A (ja) | 2007-11-01 |
DE69807746T2 (de) | 2003-01-02 |
ES2181315T3 (es) | 2003-02-16 |
ATE223244T1 (de) | 2002-09-15 |
KR20010024727A (ko) | 2001-03-26 |
JP4139844B2 (ja) | 2008-08-27 |
CA2315228A1 (en) | 1999-06-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |