DE69813898D1 - Substituierte porphyrinen - Google Patents

Substituierte porphyrinen

Info

Publication number
DE69813898D1
DE69813898D1 DE69813898T DE69813898T DE69813898D1 DE 69813898 D1 DE69813898 D1 DE 69813898D1 DE 69813898 T DE69813898 T DE 69813898T DE 69813898 T DE69813898 T DE 69813898T DE 69813898 D1 DE69813898 D1 DE 69813898D1
Authority
DE
Germany
Prior art keywords
porphyrines
substituted
oxidants
relates
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69813898T
Other languages
English (en)
Other versions
DE69813898T2 (de
Inventor
Irwin Fridovich
Ines Batinic-Haberle
James D Crapo
Brain J Day
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Jewish Health
Duke University
Original Assignee
University of Durham
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Durham, Duke University filed Critical University of Durham
Publication of DE69813898D1 publication Critical patent/DE69813898D1/de
Application granted granted Critical
Publication of DE69813898T2 publication Critical patent/DE69813898T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
DE69813898T 1997-11-03 1998-11-03 Substituierte porphyrinen Expired - Lifetime DE69813898T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6411697P 1997-11-03 1997-11-03
US64116P 1997-11-03
PCT/US1998/023287 WO1999023097A1 (en) 1997-11-03 1998-11-03 Substituted porphyrins

Publications (2)

Publication Number Publication Date
DE69813898D1 true DE69813898D1 (de) 2003-05-28
DE69813898T2 DE69813898T2 (de) 2004-03-11

Family

ID=22053669

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69813898T Expired - Lifetime DE69813898T2 (de) 1997-11-03 1998-11-03 Substituierte porphyrinen

Country Status (10)

Country Link
US (4) US6916799B2 (de)
EP (1) EP1045851B1 (de)
JP (2) JP2001521939A (de)
AT (1) ATE238307T1 (de)
AU (1) AU737650B2 (de)
CA (1) CA2309154C (de)
DE (1) DE69813898T2 (de)
ES (1) ES2198767T3 (de)
IL (1) IL135949A0 (de)
WO (1) WO1999023097A1 (de)

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US8987245B2 (en) 2008-04-02 2015-03-24 Jonathan R. Brestoff Parker Composition and method for affecting obesity and related conditions
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US10064871B2 (en) 2014-01-22 2018-09-04 Biomimetix Jv, Llc Methods of treating skin disorders
CN113402560A (zh) 2015-08-11 2021-09-17 加莱拉实验室有限责任公司 具有口服生物利用率的五氮杂大环状环络合物
IL295620B2 (en) 2017-04-13 2024-01-01 Galera Labs Llc Cancer immunotherapy combined with a macrocyclic ring pentase complex
WO2018237249A1 (en) * 2017-06-22 2018-12-27 Biomimetix Jv, Llc METHODS, COMPOSITIONS AND KITS FOR TREATING AND PREVENTING INFLAMMATORY SKIN DISEASES
US11918549B2 (en) 2017-08-25 2024-03-05 AZ Solutions LLC System and method for wound treatment and irrigation
CA3076008A1 (en) 2017-09-29 2019-04-04 Duke University Fluoro substituted porphyrin compounds, pharmaceutical compositions comprising the same, and methods of preparing and using the same
CN111100133B (zh) * 2019-12-30 2020-12-01 云南大学 一种金属卟啉化合物及其制法和应用
CA3218113A1 (en) * 2021-05-04 2022-11-10 Derek Hill Treatment of lung and airway diseases and disorders

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Also Published As

Publication number Publication date
CA2309154C (en) 2010-02-16
US20020042407A1 (en) 2002-04-11
US20070179124A1 (en) 2007-08-02
US6916799B2 (en) 2005-07-12
US20060074062A1 (en) 2006-04-06
ES2198767T3 (es) 2004-02-01
DE69813898T2 (de) 2004-03-11
JP5312404B2 (ja) 2013-10-09
EP1045851A1 (de) 2000-10-25
CA2309154A1 (en) 1999-05-14
AU1297999A (en) 1999-05-24
AU737650B2 (en) 2001-08-23
JP2010229145A (ja) 2010-10-14
US20080113956A1 (en) 2008-05-15
ATE238307T1 (de) 2003-05-15
EP1045851B1 (de) 2003-04-23
JP2001521939A (ja) 2001-11-13
IL135949A0 (en) 2001-05-20
EP1045851A4 (de) 2001-05-09
WO1999023097A1 (en) 1999-05-14

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