DE69814041D1 - Verfahren und gerät zur mikrodissektion mittels laser-fixierung - Google Patents

Verfahren und gerät zur mikrodissektion mittels laser-fixierung

Info

Publication number
DE69814041D1
DE69814041D1 DE69814041T DE69814041T DE69814041D1 DE 69814041 D1 DE69814041 D1 DE 69814041D1 DE 69814041 T DE69814041 T DE 69814041T DE 69814041 T DE69814041 T DE 69814041T DE 69814041 D1 DE69814041 D1 DE 69814041D1
Authority
DE
Germany
Prior art keywords
laser
size
changing
transfer film
spot
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69814041T
Other languages
English (en)
Other versions
DE69814041T2 (de
Inventor
M Baer
A Enright
F Head
E Todd
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Molecular Devices LLC
Original Assignee
Arcturus Engineering Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arcturus Engineering Inc filed Critical Arcturus Engineering Inc
Application granted granted Critical
Publication of DE69814041D1 publication Critical patent/DE69814041D1/de
Publication of DE69814041T2 publication Critical patent/DE69814041T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/32Micromanipulators structurally combined with microscopes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2806Means for preparing replicas of specimens, e.g. for microscopal analysis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G01N2001/2833Collecting samples on a sticky, tacky, adhesive surface
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G01N2001/2833Collecting samples on a sticky, tacky, adhesive surface
    • G01N2001/284Collecting samples on a sticky, tacky, adhesive surface using local activation of adhesive, i.e. Laser Capture Microdissection
DE69814041T 1997-02-07 1998-02-05 Verfahren und gerät zur mikrodissektion mittels laser-fixierung Expired - Lifetime DE69814041T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US3786497P 1997-02-07 1997-02-07
US37864 1997-02-07
US6073197P 1997-10-01 1997-10-01
US60731 1997-10-01
US09/018,452 US6469779B2 (en) 1997-02-07 1998-02-04 Laser capture microdissection method and apparatus
US18452 1998-02-04
PCT/US1998/002388 WO1998035216A1 (en) 1997-02-07 1998-02-05 Laser capture microdissection method and apparatus

Publications (2)

Publication Number Publication Date
DE69814041D1 true DE69814041D1 (de) 2003-06-05
DE69814041T2 DE69814041T2 (de) 2004-01-22

Family

ID=27361026

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69814041T Expired - Lifetime DE69814041T2 (de) 1997-02-07 1998-02-05 Verfahren und gerät zur mikrodissektion mittels laser-fixierung
DE69837862T Expired - Lifetime DE69837862D1 (de) 1997-02-07 1998-02-05 Verfahren und Vorrichtung zur Laser-Anheftungs-Mikrodissektion

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69837862T Expired - Lifetime DE69837862D1 (de) 1997-02-07 1998-02-05 Verfahren und Vorrichtung zur Laser-Anheftungs-Mikrodissektion

Country Status (8)

Country Link
US (10) US6469779B2 (de)
EP (1) EP0958491B1 (de)
JP (1) JP3786711B2 (de)
AT (2) ATE239215T1 (de)
AU (1) AU6150398A (de)
CA (1) CA2279992C (de)
DE (2) DE69814041T2 (de)
WO (1) WO1998035216A1 (de)

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US6184973B1 (en) 2001-02-06
US20020001074A1 (en) 2002-01-03
US6469779B2 (en) 2002-10-22
US6639657B2 (en) 2003-10-28
ATE239215T1 (de) 2003-05-15
AU6150398A (en) 1998-08-26
US6215550B1 (en) 2001-04-10
EP0958491B1 (de) 2003-05-02
US20040027556A1 (en) 2004-02-12
DE69837862D1 (de) 2007-07-12
US20010001574A1 (en) 2001-05-24
US20040106206A1 (en) 2004-06-03
US7012676B2 (en) 2006-03-14
WO1998035216A1 (en) 1998-08-13
US20060176470A1 (en) 2006-08-10
DE69814041T2 (de) 2004-01-22
US20020154288A1 (en) 2002-10-24
JP3786711B2 (ja) 2006-06-14
CA2279992A1 (en) 1998-08-13
US6924889B2 (en) 2005-08-02
CA2279992C (en) 2009-10-06
US20030058430A1 (en) 2003-03-27
US6700653B2 (en) 2004-03-02
US6697149B2 (en) 2004-02-24
EP0958491A1 (de) 1999-11-24
US6512576B1 (en) 2003-01-28
ATE363651T1 (de) 2007-06-15

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