DE69834255D1 - Verfahren zur herstellung eines granulates, geeignet zur herstellung schnell-freisetzender, im mund löslicher tabletten - Google Patents
Verfahren zur herstellung eines granulates, geeignet zur herstellung schnell-freisetzender, im mund löslicher tablettenInfo
- Publication number
- DE69834255D1 DE69834255D1 DE69834255T DE69834255T DE69834255D1 DE 69834255 D1 DE69834255 D1 DE 69834255D1 DE 69834255 T DE69834255 T DE 69834255T DE 69834255 T DE69834255 T DE 69834255T DE 69834255 D1 DE69834255 D1 DE 69834255D1
- Authority
- DE
- Germany
- Prior art keywords
- granulate
- mouse
- releasing
- fast
- producing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH179797 | 1997-07-25 | ||
CH179797 | 1997-07-25 | ||
PCT/EP1998/004514 WO1999004758A1 (en) | 1997-07-25 | 1998-07-20 | A process for the preparation of a granulate suitable to the preparation of rapidly disintegrable mouth-soluble tablets |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69834255D1 true DE69834255D1 (de) | 2006-05-24 |
DE69834255T2 DE69834255T2 (de) | 2006-09-28 |
Family
ID=4218833
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69834255T Expired - Lifetime DE69834255T2 (de) | 1997-07-25 | 1998-07-20 | Verfahren zur herstellung eines granulates, geeignet zur herstellung schnell-freisetzender, im mund löslicher tabletten |
Country Status (10)
Country | Link |
---|---|
US (1) | US6149938A (de) |
EP (1) | EP1001748B1 (de) |
JP (1) | JP4947833B2 (de) |
AT (1) | ATE323467T1 (de) |
AU (1) | AU8977698A (de) |
DE (1) | DE69834255T2 (de) |
DK (1) | DK1001748T3 (de) |
ES (1) | ES2263216T3 (de) |
PT (1) | PT1001748E (de) |
WO (1) | WO1999004758A1 (de) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH11178895A (ja) * | 1997-12-22 | 1999-07-06 | Nippon Kayaku Co Ltd | 錠剤製造における打錠障害の防止方法及び錠剤の製造方法 |
US7815937B2 (en) * | 1998-10-27 | 2010-10-19 | Biovail Laboratories International Srl | Quick dissolve compositions and tablets based thereon |
AU1323400A (en) * | 1998-10-27 | 2000-05-15 | Fuisz Technologies Ltd. | Microparticles containing peg and/or peg glyceryl esters |
IN190018B (de) * | 1999-09-28 | 2003-05-31 | Panacea Biotec Ltd | |
US6733780B1 (en) | 1999-10-19 | 2004-05-11 | Genzyme Corporation | Direct compression polymer tablet core |
WO2001085134A1 (en) * | 2000-05-12 | 2001-11-15 | Emcure Pharmaceuticals Ltd | Pharmaceutical solid compositions and process for the production of mouth dissolving tablets |
US6358526B1 (en) * | 2000-08-16 | 2002-03-19 | Rexall Sundown | Method of making tablets and tablet compositions produced therefrom |
RU2273472C2 (ru) * | 2000-10-16 | 2006-04-10 | Дайити Фармасьютикал Ко., Лтд. | Лекарственный состав, быстро распадающийся в ротовой полости, и способ его изготовления |
JP4179784B2 (ja) | 2001-02-15 | 2008-11-12 | 田辺三菱製薬株式会社 | 口腔内速崩壊性錠 |
WO2002100381A1 (en) * | 2001-06-07 | 2002-12-19 | Tanabe Seiyaku Co., Ltd. | Functional grain-containing preparations quickly disintegrated in the oral cavity |
GB0114069D0 (en) * | 2001-06-08 | 2001-08-01 | Smithkline Beecham Plc | Composition |
DE60237826D1 (de) * | 2001-07-27 | 2010-11-11 | Astellas Pharma Inc | Zusammensetzung enthaltend feine Körner mit verzögerter Freisetzung für in der Mundhöhle schnell zerfallende Tabletten |
US8017657B1 (en) * | 2001-09-07 | 2011-09-13 | Advanced Medical Instruments | Composition for the treatment and prevention of endothelial dysfunction |
CN1578657A (zh) * | 2001-09-25 | 2005-02-09 | 兰贝克赛实验室有限公司 | 制备快速溶解剂型的方法 |
WO2003041698A1 (fr) * | 2001-11-13 | 2003-05-22 | Kyowa Hakko Kogyo Co., Ltd. | Comprimes contenant des acides amines se desintegrant rapidement dans la cavite buccale et procede de fabrication de ces comprimes |
US6753009B2 (en) * | 2002-03-13 | 2004-06-22 | Mcneil-Ppc, Inc. | Soft tablet containing high molecular weight polyethylene oxide |
EP1417958A1 (de) * | 2002-11-08 | 2004-05-12 | Pari GmbH | Feuchtgranulierungsverfahren |
US20040156894A1 (en) * | 2003-02-07 | 2004-08-12 | Grother Leon Paul | Use of edible acids in fast-dispersing pharmaceutical solid dosage forms |
EP1620075B1 (de) * | 2003-05-07 | 2020-06-24 | Samyang Biopharmaceuticals Corporation | Hochplastische granulate zur herstellung von schnell schmelzenden tabletten |
US7390503B1 (en) | 2003-08-22 | 2008-06-24 | Barr Laboratories, Inc. | Ondansetron orally disintegrating tablets |
US7282217B1 (en) * | 2003-08-29 | 2007-10-16 | Kv Pharmaceutical Company | Rapidly disintegrable tablets |
CA2540040C (en) * | 2003-10-07 | 2012-09-11 | Andrx Pharmaceuticals Llc | Rapidly disintegrating formulation |
EP1715853A4 (de) * | 2004-02-17 | 2012-07-18 | Transcept Pharmaceuticals Inc | Zusammensetzungen zur abgabe von hypnotika im bereich der mundschleimhäute und verwendungsverfahren davon |
RU2359670C2 (ru) * | 2004-03-25 | 2009-06-27 | Астеллас Фарма Инк. | Композиция солифенацина или его соли для использования в твердом препарате |
US8216610B2 (en) * | 2004-05-28 | 2012-07-10 | Imaginot Pty Ltd. | Oral paracetamol formulations |
US20060039973A1 (en) * | 2004-08-19 | 2006-02-23 | Mary Aldritt | Effervescent composition including water soluble dietary fiber |
AU2005291299A1 (en) * | 2004-10-05 | 2006-04-13 | Altana Pharma Ag | Oral pharmaceutical preparation for proton pump antagonists |
US7985418B2 (en) * | 2004-11-01 | 2011-07-26 | Genzyme Corporation | Aliphatic amine polymer salts for tableting |
CN101227892B (zh) | 2005-04-08 | 2013-06-05 | 舌交付有限公司 | 口腔给药系统 |
US20060275364A1 (en) * | 2005-05-26 | 2006-12-07 | Ahmed Salah U | Flexible Solid Dosage Forms and Methods of Making and Using the Same |
US20070020186A1 (en) * | 2005-07-22 | 2007-01-25 | Alpex Pharma S.A. | Solid dosage formulations of narcotic drugs having improved buccal adsorption |
BRPI0616078B8 (pt) | 2005-09-15 | 2021-05-25 | Genzyme Corp | pó de uma formulação farmacêutica de polímero de amina, uso de tal pó e formulação em sachê para polímeros de amina |
US7811604B1 (en) | 2005-11-14 | 2010-10-12 | Barr Laboratories, Inc. | Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same |
EP1954298A4 (de) | 2005-11-28 | 2012-10-31 | Imaginot Pty Ltd | Abgabesystem für eine orale therapeutische verbindung |
EP1965771A1 (de) * | 2005-12-21 | 2008-09-10 | ADD Advanced Drug Delivery Technologies, Ltd. | Pellets enthaltend einen kern mit einem wasserlöslichen träger |
EP1986591A1 (de) * | 2006-02-10 | 2008-11-05 | LG Household & Health Care Ltd. | In situ schmelzende und gellierende tablettenzusammensetzung für die mundpflege |
CA2617688C (en) * | 2007-02-22 | 2015-08-18 | Alpex Pharma S.A. | Solid dosage formulations containing weight-loss drugs |
BE1018279A3 (fr) * | 2008-09-09 | 2010-08-03 | Squarepoint Pointcarre Sprl | Composition de nimesulide orodispersible. |
CA2750216A1 (en) * | 2008-12-15 | 2010-07-08 | Fleming And Company, Pharmaceuticals | Rapidly dissolving vitamin formulation and methods of using the same |
ES2422281T3 (es) | 2009-04-09 | 2013-09-10 | E Pharma Trento Spa | Granulado para la formulación de comprimidos bucodispersables |
DK201100161U3 (da) * | 2010-11-04 | 2012-02-24 | Norgine Bv | Formuleringer med polyethylenglycol og mannitol |
EP2537518A1 (de) * | 2011-06-24 | 2012-12-26 | Elanco Animal Health Ireland Limited | Schnell zerfallendene Azaperon-Granulatformulierungen |
KR20160108828A (ko) | 2013-11-11 | 2016-09-20 | 임팩스 라보라토리즈, 인코포레이티드 | 신속하게 붕괴되는 제형 및 사용 방법 |
US9456981B2 (en) | 2014-02-13 | 2016-10-04 | Cadila Healthcare Limited | Stable orally disintegrating tablets of hyoscyamine |
CN107249567B (zh) | 2014-11-21 | 2021-08-03 | 拜尔哈文制药股份有限公司 | 利鲁唑的舌下给药 |
US9925138B2 (en) | 2015-01-20 | 2018-03-27 | Handa Pharmaceuticals, Llc | Stable solid fingolimod dosage forms |
EP3458053B1 (de) | 2016-05-20 | 2021-12-08 | Biohaven Pharmaceutical Holding Company Ltd. | Verwendung von riluzol, riluzolprodrugs oder riluzolanaloga mit immuntherapien zur behandlung von krebs |
KR20240031326A (ko) | 2016-12-31 | 2024-03-07 | 바이오엑셀 테라퓨틱스 인코포레이티드 | 불안의 치료를 위한 설하 덱스메데토미딘의 용도 |
US20210023061A1 (en) | 2017-11-12 | 2021-01-28 | Biohaven Pharmaceutical Holding Company Ltd. | Use of riluzole prodrugs to treat ataxias |
CA3103431A1 (en) | 2018-06-27 | 2020-01-02 | Bioxcel Therapeutics, Inc. | Film formulations containing dexmedetomidine and methods of producing them |
CA3145388A1 (en) | 2019-07-19 | 2021-01-28 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
JP6813922B1 (ja) * | 2019-12-10 | 2021-01-13 | ノーベルファーマ株式会社 | メラトニン含有顆粒剤 |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5675436A (en) * | 1979-11-22 | 1981-06-22 | Eisai Co Ltd | Solid pharmaceutical containing cobamamide or mecobalamin |
FR2561916B1 (fr) * | 1984-03-30 | 1987-12-11 | Lafon Labor | Forme galenique pour administration orale et son procede de preparation par lyophilisation d'une emission huile dans eau |
US4496684A (en) * | 1984-06-01 | 1985-01-29 | Olin Corporation | Uretdione group-containing polyurethane oligomers and aqueous dispersions thereof |
CA1265785A (en) * | 1984-06-04 | 1990-02-13 | Kumi Yoshida | Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them |
US4642903A (en) * | 1985-03-26 | 1987-02-17 | R. P. Scherer Corporation | Freeze-dried foam dosage form |
US4855326A (en) * | 1987-04-20 | 1989-08-08 | Fuisz Pharmaceutical Ltd. | Rapidly dissoluble medicinal dosage unit and method of manufacture |
US4851226A (en) * | 1987-11-16 | 1989-07-25 | Mcneil Consumer Products Company | Chewable medicament tablet containing means for taste masking |
US5211957A (en) * | 1988-03-25 | 1993-05-18 | Ciba-Geigy Corporation | Solid rapidly disintegrating dosage form |
US5112616A (en) * | 1988-11-30 | 1992-05-12 | Schering Corporation | Fast dissolving buccal tablet |
US5424074A (en) * | 1989-06-20 | 1995-06-13 | Otsuka Pharmaceutical Co., Ltd. | Pharmaceutical composition for potassium supplementation |
US5178878A (en) * | 1989-10-02 | 1993-01-12 | Cima Labs, Inc. | Effervescent dosage form with microparticles |
ES2097155T3 (es) * | 1989-10-02 | 1997-04-01 | Cima Labs Inc | Forma de dosificacion efervescente y metodo de administracion. |
US5188825A (en) * | 1989-12-28 | 1993-02-23 | Iles Martin C | Freeze-dried dosage forms and methods for preparing the same |
JP3125221B2 (ja) * | 1990-09-01 | 2001-01-15 | 大正製薬株式会社 | ソファルコン含有固形製剤 |
WO1993003409A1 (en) * | 1991-08-09 | 1993-02-18 | Capricornia Contact Lens Pty. Ltd. | Toric lens with axis mislocation latitude |
US5223624A (en) * | 1991-08-22 | 1993-06-29 | Baebler Fridolin | Modified gamma-quinacridone pigment |
EP0553777B1 (de) * | 1992-01-29 | 2002-04-24 | Takeda Chemical Industries, Ltd. | Schnellösliche Tablette und ihre Herstellung |
US5343672A (en) * | 1992-12-01 | 1994-09-06 | Scherer Ltd R P | Method for manufacturing freeze dried dosages in a multilaminate blister pack |
IT1264696B1 (it) * | 1993-07-09 | 1996-10-04 | Applied Pharma Res | Forme farmaceutiche destinate alla somministrazione orale in grado di rilasciare sostanze attive a velocita' controllata e differenziata |
ATE208615T1 (de) * | 1993-07-09 | 2001-11-15 | Scherer Corp R P | Verfahren zur herstellung von gefriergetrockneten arzneistoffdosierungsformen |
CA2164344C (en) * | 1993-08-30 | 2004-06-29 | Stanley Lech | Tablet coating based on a melt-spun mixture of a saccharide and a polymer |
US5457895A (en) * | 1993-10-01 | 1995-10-17 | R. P. Scherer Corporation | Method of identifying freeze-dried dosage forms |
CA2181990C (en) * | 1994-01-27 | 2000-09-26 | Loyd V. Allen, Jr. | Rapidly dissolving oral dosage form |
JP3045930B2 (ja) * | 1994-06-16 | 2000-05-29 | 共成製薬株式会社 | 消化管用薬剤 |
DE19509805A1 (de) * | 1995-03-21 | 1996-09-26 | Basf Ag | Transparente, schnell freisetzende Zubereitungen von nichtsteroidalen Analgetica |
US5607697A (en) * | 1995-06-07 | 1997-03-04 | Cima Labs, Incorporated | Taste masking microparticles for oral dosage forms |
JPH0948726A (ja) * | 1995-08-07 | 1997-02-18 | Tanabe Seiyaku Co Ltd | 口腔内速崩壊性製剤およびその製法 |
JPH09194381A (ja) * | 1996-01-17 | 1997-07-29 | Kowa Co | カルシウム塩含有チュアブル錠 |
EP0839526A3 (de) * | 1996-10-31 | 1999-01-07 | Takeda Chemical Industries, Ltd. | Festes pharmazeutisches Präparat mit schneller Auflösungs- oder Disintegrationeigenschaften |
US5792958A (en) * | 1997-01-21 | 1998-08-11 | Honeywell Inc. | Pressure sensor with a compressible insert to prevent damage from freezing |
-
1998
- 1998-07-20 EP EP98941376A patent/EP1001748B1/de not_active Expired - Lifetime
- 1998-07-20 DE DE69834255T patent/DE69834255T2/de not_active Expired - Lifetime
- 1998-07-20 JP JP2000503819A patent/JP4947833B2/ja not_active Expired - Fee Related
- 1998-07-20 PT PT98941376T patent/PT1001748E/pt unknown
- 1998-07-20 AT AT98941376T patent/ATE323467T1/de active
- 1998-07-20 AU AU89776/98A patent/AU8977698A/en not_active Abandoned
- 1998-07-20 DK DK98941376T patent/DK1001748T3/da active
- 1998-07-20 WO PCT/EP1998/004514 patent/WO1999004758A1/en active IP Right Grant
- 1998-07-20 ES ES98941376T patent/ES2263216T3/es not_active Expired - Lifetime
- 1998-07-23 US US09/122,037 patent/US6149938A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE69834255T2 (de) | 2006-09-28 |
US6149938A (en) | 2000-11-21 |
JP4947833B2 (ja) | 2012-06-06 |
AU8977698A (en) | 1999-02-16 |
JP2001510785A (ja) | 2001-08-07 |
EP1001748B1 (de) | 2006-04-19 |
WO1999004758A1 (en) | 1999-02-04 |
ATE323467T1 (de) | 2006-05-15 |
ES2263216T3 (es) | 2006-12-01 |
PT1001748E (pt) | 2006-08-31 |
DK1001748T3 (da) | 2006-08-21 |
EP1001748A1 (de) | 2000-05-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |