DE69836736D1 - Vorrichtung zur automatischen elektrodenpositionierung - Google Patents

Vorrichtung zur automatischen elektrodenpositionierung

Info

Publication number
DE69836736D1
DE69836736D1 DE69836736T DE69836736T DE69836736D1 DE 69836736 D1 DE69836736 D1 DE 69836736D1 DE 69836736 T DE69836736 T DE 69836736T DE 69836736 T DE69836736 T DE 69836736T DE 69836736 D1 DE69836736 D1 DE 69836736D1
Authority
DE
Germany
Prior art keywords
automatic electrode
methods
electrode positioning
cell
automatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69836736T
Other languages
English (en)
Other versions
DE69836736T2 (de
Inventor
Soren-Peter Olesen
Palle Christophersen
Morten Bech
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sophion Bioscience AS
Original Assignee
Sophion Bioscience AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sophion Bioscience AS filed Critical Sophion Bioscience AS
Application granted granted Critical
Publication of DE69836736D1 publication Critical patent/DE69836736D1/de
Publication of DE69836736T2 publication Critical patent/DE69836736T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48728—Investigating individual cells, e.g. by patch clamp, voltage clamp
DE69836736T 1997-05-01 1998-04-29 Vorrichtung zur automatischen elektrodenpositionierung Expired - Lifetime DE69836736T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
DK49697 1997-05-01
DK49697 1997-05-01
DK90297 1997-08-01
DK90297 1997-08-01
DK115197 1997-10-08
DK115197 1997-10-08
PCT/DK1998/000167 WO1998050791A1 (en) 1997-05-01 1998-04-29 An automatic electrode positioning apparatus

Publications (2)

Publication Number Publication Date
DE69836736D1 true DE69836736D1 (de) 2007-02-08
DE69836736T2 DE69836736T2 (de) 2007-10-04

Family

ID=27220731

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69836736T Expired - Lifetime DE69836736T2 (de) 1997-05-01 1998-04-29 Vorrichtung zur automatischen elektrodenpositionierung

Country Status (11)

Country Link
US (1) US6470226B1 (de)
EP (1) EP0980523B1 (de)
JP (1) JP2002507278A (de)
AT (1) ATE349694T1 (de)
AU (1) AU729397B2 (de)
CA (1) CA2285279A1 (de)
DE (1) DE69836736T2 (de)
DK (1) DK0980523T3 (de)
IL (1) IL131823A0 (de)
NZ (1) NZ337814A (de)
WO (1) WO1998050791A1 (de)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59801410D1 (de) 1997-12-17 2001-10-11 Ecole Polytech Positionierung und elektrophysiologische charakterisierung einzelner zellen und rekonstituierter membransysteme auf mikrostrukturierten trägern
US20020144905A1 (en) 1997-12-17 2002-10-10 Christian Schmidt Sample positioning and analysis system
US7244349B2 (en) 1997-12-17 2007-07-17 Molecular Devices Corporation Multiaperture sample positioning and analysis system
GB9812783D0 (en) 1998-06-12 1998-08-12 Cenes Ltd High throuoghput screen
ATE513209T1 (de) 1998-12-05 2011-07-15 Xention Ltd Grenzflächen-patch-clamp-verfahren und -gerät
JP3582390B2 (ja) * 1999-01-13 2004-10-27 松下電器産業株式会社 微細物体の自動探索装置
EP1171791B1 (de) 1999-04-19 2005-11-02 Imperial College Innovations Limited Optische mikroskopie und deren verwendung bei der untersuchung von zellen
WO2001059447A1 (en) * 2000-02-11 2001-08-16 Yale University Planar patch clamp electrodes
GB0006748D0 (en) * 2000-03-21 2000-05-10 Cenes Ltd Improved interface patch clamping
US7011939B2 (en) * 2000-03-22 2006-03-14 Abbott Laboratories Apparatus and method for electrophysiological testing
US7067046B2 (en) 2000-08-04 2006-06-27 Essen Instruments, Inc. System for rapid chemical activation in high-throughput electrophysiological measurements
US7270730B2 (en) * 2000-08-04 2007-09-18 Essen Instruments, Inc. High-throughput electrophysiological measurement system
US6461860B2 (en) * 2001-01-25 2002-10-08 Axon Instruments, Inc. Alignment mechanism for two-electrode voltage-clamp perfusion chamber for electrophysiological testing of oocytes
FR2820756B1 (fr) * 2001-02-09 2004-01-23 Daniel Attias Incubateur et procede d'incubation menageant l'organisme mis a incuber
US6815197B2 (en) * 2001-02-16 2004-11-09 Multi Channel System Mcs Gmbh Apparatus for conducting electrophysiological measurements on cells
AU2002307218A1 (en) 2001-03-24 2002-10-08 Aviva Biosciences Corporation Biochips including ion transport detecting structures and methods of use
US20060029955A1 (en) 2001-03-24 2006-02-09 Antonio Guia High-density ion transport measurement biochip devices and methods
JP2005506056A (ja) 2001-06-06 2005-03-03 ニューロサーチ、アクティーゼルスカブ カチオン伝導ｇａｂａａレセプターおよびその使用
US20050153276A1 (en) * 2001-08-06 2005-07-14 Vanderbilt University System and methods for discriminating an agent
EP1434850A2 (de) * 2001-09-05 2004-07-07 Essen Instruments, Inc. Elektrophysiologisches messsystem mit hohem durchsatz
AU2002337745A1 (en) * 2001-09-28 2003-04-14 University Of North Carolina At Chapel Hill Methods and systems for three-dimensional motion control and tracking of a mechanically unattached magnetic probe
DE60217393T2 (de) * 2001-11-27 2007-10-18 Cellectricon Ab Verfahren zur kombinierten parallelen zuführung von agentien und elektroporation für zellstrukturen und verwendung davon
WO2003047738A2 (en) 2001-11-30 2003-06-12 Bristol-Myers Squibb Company Liquid interface configurations for automated patch clamp recording
AU2002352988A1 (en) 2001-11-30 2003-06-17 Bristol-Myers Squibb Company Pipette configurations and arrays thereof for measuring cellular electrical properties
EP2347824A3 (de) * 2002-02-12 2012-03-07 Cellectricon Ab Systeme und Verfahren zur schnellen Änderung der Lösungsumgebung um Sensoren
US7470518B2 (en) * 2002-02-12 2008-12-30 Cellectricon Ab Systems and method for rapidly changing the solution environment around sensors
US7136696B2 (en) 2002-04-05 2006-11-14 The Cleveland Clinic Foundation Neuron signal analysis system and method
EP1501924A4 (de) 2002-05-04 2006-05-24 Aviva Biosciences Corp Vorrichtung mit strukturen nachweisendem ionentransport und verwendungsverfahren
IL151315A (en) * 2002-08-18 2010-04-29 Maroon J Abu Nassar Fixture for electrode placement
JP4386835B2 (ja) * 2002-08-21 2009-12-16 セレクトリコン アーベー パッチクランプ記録において高抵抗固着を獲得して維持するシステム及び方法
WO2004036202A1 (en) 2002-10-16 2004-04-29 Cellectricon Ab Nanoelectrodes and nanotips for recording transmembrane currents in a plurality of cells
US7119645B2 (en) * 2003-02-25 2006-10-10 The University Of North Carolina Methods and systems for controlling motion of and tracking a mechanically unattached probe
US7015376B2 (en) * 2004-01-30 2006-03-21 Pioneer Hi-Bred International, Inc. Soybean variety 95M80
US20050256541A1 (en) * 2004-04-30 2005-11-17 Medtronic, Inc. Catheter with temporary stimulation electrode
US20050241940A1 (en) * 2004-05-03 2005-11-03 Wyeth Fast perfusion system and patch clamp technique utilizing an interface chamber system having high throughput and low volume requirements
US7465558B2 (en) * 2004-05-12 2008-12-16 Wyeth Perfusion system and apparatus for automated multi-channel patch-clamp recordings utilizing inside-out whole-cell configuration
WO2006020187A2 (en) * 2004-07-16 2006-02-23 The University Of North Carolina At Chapel Hill Methods, systems and computer program products for full spectrum projection
US8095210B2 (en) * 2007-01-19 2012-01-10 California Institute Of Technology Prosthetic devices and methods and systems related thereto
US8490469B2 (en) * 2007-02-22 2013-07-23 The University Of North Carolina Methods and systems for multiforce high throughput screening
DE102008010436A1 (de) * 2008-02-21 2009-09-03 Berthold Technologies Gmbh & Co. Kg Vorrichtung und Verfahren zur Messung von Lumineszenz und Fluoreszenz von transfizierten Zellen oder Organteilen
JP5877413B2 (ja) * 2008-11-12 2016-03-08 カー サイエンティフィック インストゥルメンツ リミテッド 生物組織サンプルからの電気的活性を試験するための装置
DE102008058065A1 (de) * 2008-11-18 2010-05-20 Diasys Diagnostic Systems Gmbh Automatisierte Analysevorrichtung mit einer automatischen Pipettiervorrichtung und mit einer Messvorrichtung zum Bestimmen der Position der Pipettiernadelspitze
JP5511949B2 (ja) 2009-06-25 2014-06-04 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 体液レオロジーを評価するための、作動され表面に付着したポストを使用するための方法及びシステム
BE1018834A3 (nl) * 2009-07-21 2011-09-06 Praet Peter Van Inspectie camera gemonteerd op een medische diagnose automaat.
EP2302375B1 (de) 2009-09-29 2012-09-12 Karlsruher Institut für Technologie Verfahren und Vorrichtung zum Erfassen der Stromspannungskurve einer Zelle
DK2710109T3 (en) * 2011-05-19 2018-01-22 Nmi Naturwissenschaftliches Und Medizinisches Institut An Der Univ Tuebingen Method and use of a device for automated positioning of a microsystem for manipulating a spherical micro object
CN102866247A (zh) * 2012-09-26 2013-01-09 东南大学 一种全自动膜片钳电生理纪录系统及记录方法
JP5778354B2 (ja) * 2012-10-25 2015-09-16 浜松ホトニクス株式会社 細胞観察装置、電気刺激装置、及び細胞観察方法
EP2913391B1 (de) * 2012-10-25 2020-07-01 Hamamatsu Photonics K.K. Zellbeobachtungsvorrichtung und zellbeobachtungsverfahren
WO2014085804A1 (en) 2012-11-30 2014-06-05 The University Of North Carolina At Chapel Hill Methods, systems, and computer readable media for determining physical properties of a specimen in a portable point of care diagnostic device
US10324080B2 (en) * 2015-11-17 2019-06-18 Purdue Research Foundation Systems and methods for automated image-guided patch-clamp electrophysiology in vitro
US20210063341A1 (en) * 2015-12-05 2021-03-04 Mohammad Abdolahad Electromechanical approach for cancer detection
DK179325B1 (en) 2016-03-17 2018-04-30 Itu Business Dev A/S A robot and a method of controlling a robot
US10702690B2 (en) 2017-02-03 2020-07-07 Infinitesimal Llc Electroporation system with micromanipulator and probe
EP4231011A1 (de) * 2022-02-16 2023-08-23 Luigs & Neumann Feinmechanik und Elektrotechnik GmbH Vorrichtungen und verfahren für patch-clamp-messtechnik

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3718066A1 (de) * 1987-05-29 1988-12-08 Zeiss Carl Fa Verfahren zur mikroinjektion in zellen bzw. zum absaugen aus einzelnen zellen oder ganzer zellen aus zellkulturen
US5108926A (en) * 1987-09-08 1992-04-28 Board Of Regents, The University Of Texas System Apparatus for the precise positioning of cells
US4932044A (en) * 1988-11-04 1990-06-05 Yale University Tissue analyzer
US5991028A (en) * 1991-02-22 1999-11-23 Applied Spectral Imaging Ltd. Spectral bio-imaging methods for cell classification
CA2084099C (en) * 1991-12-06 1996-06-18 James V. Bacus Method and apparatus for automated cell analysis
US5484731A (en) * 1993-05-26 1996-01-16 Becton, Dickinson And Company Multiwell in-vitro fertilization plate
WO1996013721A1 (en) * 1994-10-28 1996-05-09 Neurosearch A/S Patch clamp apparatus and technique having high throughput and low fluid volume requirements
AU1059997A (en) * 1995-11-08 1997-05-29 Trustees Of Boston University Cellular physiology workstations for automated data acquisition and perfusion control

Also Published As

Publication number Publication date
DE69836736T2 (de) 2007-10-04
CA2285279A1 (en) 1998-11-12
AU7205498A (en) 1998-11-27
JP2002507278A (ja) 2002-03-05
AU729397B2 (en) 2001-02-01
EP0980523B1 (de) 2006-12-27
IL131823A0 (en) 2001-03-19
DK0980523T3 (da) 2007-04-30
EP0980523A1 (de) 2000-02-23
NZ337814A (en) 2001-04-27
ATE349694T1 (de) 2007-01-15
WO1998050791A1 (en) 1998-11-12
US6470226B1 (en) 2002-10-22

Similar Documents

Publication Publication Date Title
DE69836736D1 (de) Vorrichtung zur automatischen elektrodenpositionierung
ATE338951T1 (de) Vorrichtung zur automatischen durchführung von laboratoriumprüfungen
DE3788026D1 (de) Verfahren und Vorrichtung zur Kultivierung von Zellen.
DE3689856T2 (de) Analyseverfahren und vorrichtung für biologische specimen.
DE69602419T2 (de) Vorrichtung zur gewinnung von sauerstoff
DE59702254D1 (de) Vorrichtung zur durchführung von untersuchungen an zellproben und dergleichen
DE59611033D1 (de) Vorrichtung zur Prüfung von ferromagnetischen Materialien
DE69636183D1 (de) Vorrichtung zur Prüfung von Halbleitersubstraten
DE69316419D1 (de) Vorrichtung zur feinelektrochemischen Bearbeitung
DE69818650D1 (de) Gerät und methoden zum einfnag und zur analyse von partikel-einheiten
DE69719882T2 (de) Abtrennungsverfahren für Platten und Vorrichtung zur Durchführung dieses Verfahrens
DE69839689D1 (de) Probenpositionierungsverfahren und Vorrichtung zur dessen Durchführung
DE69725636D1 (de) Gerät zur harmonischen Wellenformanalyse in einem elektrischen System
DE69735547D1 (de) Verfahren zur induzierung von immunsupprimierten zellen und vorrichtung zu deren kultivierung
DE69106099D1 (de) Verfahren und Vorrichtung zur Lieferung von einem Gas an einen sehr empfindlichen Analysator.
DE50213056D1 (de) Sensoranordnung, vorrichtung und verfahren zur ampologischen wirkort- und/oder wirkstofftestung
DE69629739D1 (de) Vorrichtung zur Inspektion von O-Ringen
DE69628898D1 (de) Vorrichtung zur ausseraxialen Prüfung von anisotropen Materialien
DE69837575D1 (de) Vorrichtung und Verfahren zur Inkubation von Teststreifen
DE68922562T2 (de) Verfahren und Vorrichtung zur Aufbereitung von Proben für die Ionenanalyse.
DE59408020D1 (de) Vorrichtung zur Prüfung von Modulen
DE68912661D1 (de) Verfahren und Vorrichtung für Zellkultur.
DE69602725D1 (de) Gestell zum tragen von einem elektischen apparat und verbindungsstück
DE58909849D1 (de) Verfahren und Vorrichtung zur Quecksilberanalyse
DE59705884D1 (de) Vorrichtung zur Durchführung von elektrochemischen und/oder optischen Messvorgängen in Flüssigkeiten

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: STROHSCHAENK UND KOLLEGEN, 85521 OTTOBRUNN