DE69839586D1 - Verwendung von ingenan derivaten zur herstellung eines medikaments zur krebsbekämpfung - Google Patents
Verwendung von ingenan derivaten zur herstellung eines medikaments zur krebsbekämpfungInfo
- Publication number
- DE69839586D1 DE69839586D1 DE69839586T DE69839586T DE69839586D1 DE 69839586 D1 DE69839586 D1 DE 69839586D1 DE 69839586 T DE69839586 T DE 69839586T DE 69839586 T DE69839586 T DE 69839586T DE 69839586 D1 DE69839586 D1 DE 69839586D1
- Authority
- DE
- Germany
- Prior art keywords
- compounds
- euphorbia
- jatrophanes
- plants
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPO8640A AUPO864097A0 (en) | 1997-08-19 | 1997-08-19 | Anti-cancer compounds |
PCT/AU1998/000656 WO1999008994A1 (en) | 1997-08-19 | 1998-08-19 | Anti-cancer compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69839586D1 true DE69839586D1 (de) | 2008-07-17 |
Family
ID=3802927
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69839586T Expired - Lifetime DE69839586D1 (de) | 1997-08-19 | 1998-08-19 | Verwendung von ingenan derivaten zur herstellung eines medikaments zur krebsbekämpfung |
Country Status (17)
Country | Link |
---|---|
US (4) | US6432452B1 (de) |
EP (1) | EP1015413B1 (de) |
JP (3) | JP2001515059A (de) |
CN (1) | CN1266421B (de) |
AT (1) | ATE397580T1 (de) |
AU (1) | AUPO864097A0 (de) |
BE (1) | BE2013C026I2 (de) |
BR (1) | BR9811327A (de) |
CA (1) | CA2301082C (de) |
CY (2) | CY1108303T1 (de) |
DE (1) | DE69839586D1 (de) |
DK (1) | DK1015413T3 (de) |
ES (1) | ES2308810T3 (de) |
HU (2) | HU228862B1 (de) |
LU (1) | LU92185I2 (de) |
PT (1) | PT1015413E (de) |
WO (1) | WO1999008994A1 (de) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPO864097A0 (en) * | 1997-08-19 | 1997-09-11 | Peplin Pty Ltd | Anti-cancer compounds |
US6822267B1 (en) * | 1997-08-20 | 2004-11-23 | Advantest Corporation | Signal transmission circuit, CMOS semiconductor device, and circuit board |
US7078434B1 (en) * | 1999-08-12 | 2006-07-18 | Societe De Conseils De Recherches Et D'applications Scientifiques Sas | Use of Ginkgo extract |
AUPQ801700A0 (en) | 2000-06-07 | 2000-06-29 | Peplin Research Pty Ltd | Enzyme and viral activation |
AU748542B2 (en) * | 2000-06-07 | 2002-06-06 | Leo Laboratories Limited | Therapeutic agents - III |
AUPQ923100A0 (en) | 2000-08-07 | 2000-08-31 | Peplin Research Pty Ltd | Treatment of prostate cancer |
US6923993B2 (en) * | 2001-12-12 | 2005-08-02 | Nicholas J. Donato | Process of isolating extract from the Euphorbia obesa plant and methods for using the same |
MY139563A (en) | 2002-09-04 | 2009-10-30 | Bristol Myers Squibb Co | Heterocyclic aromatic compounds useful as growth hormone secretagogues |
US7154002B1 (en) | 2002-10-08 | 2006-12-26 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
US7250514B1 (en) | 2002-10-21 | 2007-07-31 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
EP1608628A2 (de) | 2003-03-17 | 2005-12-28 | Takeda San Diego, Inc. | Inhibitoren der histondeacetylase |
JP4777251B2 (ja) | 2003-10-14 | 2011-09-21 | バクスター・インターナショナル・インコーポレイテッド | ビタミンkエポキシド還元酵素複合体サブユニット1vkorc1、クマリンおよびその誘導体の治療標的 |
US20050137234A1 (en) * | 2003-12-19 | 2005-06-23 | Syrrx, Inc. | Histone deacetylase inhibitors |
WO2005079471A2 (en) * | 2004-02-17 | 2005-09-01 | University Of South Florida | Cytotoxin compound and method of isolation |
WO2005084712A2 (en) * | 2004-02-27 | 2005-09-15 | Antisense Pharma Gmbh | Use of an oligonucleotide or its active derivative for the preparation of a pharmaceutical composition for inhibiting the formation of metastases in cancer treatment |
DE102004044428A1 (de) * | 2004-09-14 | 2006-03-30 | Toximed Gmbh | Verfahren und pharmazeutischer Wirkstoff zur Bekämpfung von Plasmodien |
NZ554710A (en) * | 2004-12-13 | 2010-03-26 | Peplin Research Pty Ltd | Treatment of solid cancers with angeloyl substituted ingenanes |
AU2005316185B2 (en) * | 2004-12-13 | 2012-04-12 | Leo Laboratories Limited | Treatment of solid cancers |
EP1824831A2 (de) | 2004-12-16 | 2007-08-29 | Takeda San Diego, Inc. | Histondeacetylase-inhibitoren |
JP2008540574A (ja) | 2005-05-11 | 2008-11-20 | タケダ サン ディエゴ インコーポレイテッド | ヒストンデアセチラーゼ阻害剤 |
US20090035403A2 (en) * | 2005-06-16 | 2009-02-05 | Mmi Corporation | Novel anticancer agent, methods for obtaining the same and pharmaceutical compositions thereof |
US7655620B2 (en) * | 2005-07-07 | 2010-02-02 | Cancure Laboratories, Llc | Use of one or more metal carriers to selectively kill mammalian cells |
ZA200800901B (en) | 2005-07-14 | 2010-05-26 | Takeda San Diego Inc | Histone deacetylase inhibitors |
US9597311B2 (en) * | 2005-09-27 | 2017-03-21 | Robert Benson Aylor | Suppression and prevention of tumors |
CN101360506A (zh) * | 2005-11-25 | 2009-02-04 | 派普林研究股份有限公司 | 创伤愈合的方法 |
WO2007065925A2 (de) * | 2005-12-07 | 2007-06-14 | Toximed Gmbh | Zusammensetzung zur behandlung von melanomen und hautunreinheiten sowie kosmetisches hautpflegemittel |
GB0525680D0 (en) | 2005-12-16 | 2006-01-25 | Peplin Ltd | Therapeutic compositions |
WO2007084390A2 (en) * | 2006-01-13 | 2007-07-26 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
US20080069809A1 (en) * | 2006-04-20 | 2008-03-20 | Ogbourne Steven M | Compositions and methods for the diagnosis and treatment of cancer |
US20080207738A1 (en) * | 2007-02-28 | 2008-08-28 | Cancure Laboratories, Llc | Drug combinations to treat drug resistant tumors |
US10143638B2 (en) * | 2009-02-13 | 2018-12-04 | Leo Laboratories Limited | Method of treating skin with ingenol mebutate |
TWI389699B (zh) * | 2009-02-13 | 2013-03-21 | Univ Kaohsiung Medical | 用於誘導細胞凋亡之樟芝子實體乙醇萃取物及其製備方法 |
DK2558435T3 (en) | 2010-04-16 | 2017-08-14 | Leo Pharma As | ORTHOROMBIC CRYSTALLINIC INGENOLMBUTATE |
WO2011139172A1 (en) * | 2010-05-06 | 2011-11-10 | Goran Milosavljevic | Diterpene compounds with antineoplastic activities and pharmaceutical compositions comprising same |
JP6116481B2 (ja) * | 2010-10-25 | 2017-04-19 | ニーキ ファーマ インコーポレイテッド | 神経内分泌腫瘍を治療する方法 |
WO2012080466A2 (en) | 2010-12-17 | 2012-06-21 | Leo Pharma A/S | Ingenols for treating seborrheic keratosis |
WO2012083953A1 (en) | 2010-12-22 | 2012-06-28 | Leo Pharma A/S | Ingenol-3-acylates iii and ingenol-3-carbamates |
WO2012083954A1 (en) | 2010-12-22 | 2012-06-28 | Leo Pharma A/S | 3-acyl-ingenols ii |
WO2012085189A1 (en) | 2010-12-22 | 2012-06-28 | Leo Pharma A/S | Ingenol-3-acylates i |
US8858953B2 (en) | 2011-05-09 | 2014-10-14 | Yu-Hwa Peter Sheng | Herbal composition for treating cancer |
WO2012176015A1 (en) | 2011-06-24 | 2012-12-27 | Leo Pharma A/S | Methods for treating uv-damaged skin and scc tumors and for removing tattoos with topical ingenol mebutate |
KR101374760B1 (ko) * | 2011-10-26 | 2014-03-17 | 한국생명공학연구원 | 포볼 타입의 디테르펜 화합물 및 이를 포함하는 바이러스 감염 질환의 치료 또는 예방용 약학적 조성물 |
ES2640612T3 (es) | 2012-06-26 | 2017-11-03 | Leo Laboratories Limited | 3-O-heteroaril-ingenol |
CN103655674A (zh) * | 2012-09-11 | 2014-03-26 | 清华大学深圳研究生院 | 乳浆大戟提取物及其制备方法和应用 |
KR101578404B1 (ko) | 2014-03-18 | 2015-12-18 | 원광대학교 산학협력단 | 대극속 식물 추출물 또는 분획물을 유효성분으로 포함하는 암 예방 또는 치료용 조성물 |
CN107210718A (zh) * | 2014-11-20 | 2017-09-26 | 迪芬尼香港有限公司 | 使用多速率fir和全通iir滤波器均衡扬声器系统的声学响应的方法和装置 |
CN106916580A (zh) * | 2015-10-01 | 2017-07-04 | 钱秀英 | 一种基于生物显色技术以服务于物联网的储物箱 |
CN105255477B (zh) * | 2015-10-01 | 2017-05-10 | 青岛大学附属医院 | 判断时间的生物显色剂 |
US9758786B2 (en) | 2016-02-09 | 2017-09-12 | Autotelic, Llc | Compositions and methods for treating pancreatic cancer |
US10722484B2 (en) | 2016-03-09 | 2020-07-28 | K-Gen, Inc. | Methods of cancer treatment |
MY197240A (en) | 2016-09-02 | 2023-06-07 | Thailand Center Of Excellence For Life Sciences | Method for preparing an extract of hevea latex and composition thereof |
CN110663685B (zh) * | 2019-10-23 | 2021-10-12 | 扬州大学 | 一种介孔二氧化硅负载ppte的纳米农药制剂 |
CN112441924A (zh) * | 2020-12-11 | 2021-03-05 | 浙江工业大学 | 巨大戟二萜化合物及其提取方法与应用 |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2902506A1 (de) * | 1979-01-23 | 1980-07-24 | Deutsches Krebsforsch | Verwendung von nicht oder nur gering irritierenden und/oder promovierenden diterpenalkoholen und von derivaten davon als antineoplastische mittel |
JPS5813571A (ja) * | 1981-07-14 | 1983-01-26 | Sagami Chem Res Center | ジヒドロフラン誘導体及びその製造方法 |
US4418064A (en) | 1982-09-29 | 1983-11-29 | The United States Of America As Represented By The Secretary Of Agriculture | Chemotherapeutically active maytansinoids: treflorine, trenudine, and N-methyltrenudone |
US4560774A (en) | 1982-11-17 | 1985-12-24 | Arizona State University | Macrocyclic lactones |
IL82811A0 (en) | 1986-06-11 | 1987-12-20 | Alder Res Center Corp | Anti-inflammatory compositions containing methanol derivatives and novel compounds contained therein |
US5886019A (en) | 1986-06-11 | 1999-03-23 | Procyon Pharmaceuticals, Inc. | Protein kinase C modulators. F. |
US5145842A (en) | 1986-06-11 | 1992-09-08 | Alder Research Center Limited Partnership | Protein kinase c. modulators. d. |
US5716968A (en) | 1986-06-11 | 1998-02-10 | Procyon Pharmaceuticals, Inc. | Protein kinase C modulators. H. |
US5750568A (en) | 1986-06-11 | 1998-05-12 | Procyon Pharmaceuticals, Inc. | Protein kinase C Modulators. L. |
US5891870A (en) | 1986-06-11 | 1999-04-06 | Procyon Pharmaceuticals, Inc. | Protein kinase C modulators Q |
US5891906A (en) | 1986-06-11 | 1999-04-06 | Procyon Pharmaceuticals, Inc. | Polyacetate-derived phorboids having anti-inflammatory and other uses |
US5643948A (en) | 1986-06-11 | 1997-07-01 | Procyon Pharmaceuticals, Inc. | Protein kinase C modulators. K. |
US5886017A (en) | 1986-06-11 | 1999-03-23 | Procyon Pharmaceuticals, Inc. | Protein kinase C modulators. E. |
DE3805965A1 (de) | 1988-02-25 | 1989-09-07 | Tamas Geb Szenasi Eszter | Verwendung der pflanze euphorbia hirta l. und ihrer extrakte sowie ihrer wirkstoffe |
DE4102054A1 (de) * | 1991-01-24 | 1992-07-30 | Geb Szenasi Tamas | Verwendung der pflanze euphorbia hirta l. und ihrer extrakte sowie ihrer wirkstoffe |
CN1047084C (zh) * | 1993-03-30 | 1999-12-08 | 刘振宪 | 人参口服液及其制造方法 |
US6593371B1 (en) | 1993-05-19 | 2003-07-15 | Jeff J. Staggs | Treatment for wart and related disorders |
CN1048164C (zh) * | 1993-08-24 | 2000-01-12 | 吴雪姣 | 复方菝葜口服液 |
JP2913451B2 (ja) | 1994-06-22 | 1999-06-28 | 株式会社イナックス | 防水パンの高さ調整構造 |
JPH08245505A (ja) * | 1994-09-09 | 1996-09-24 | Tosoh Corp | ジテルペン誘導体、その製造法及びそれを有効成分として含有する抗腫瘍剤 |
JPH08176002A (ja) * | 1994-12-27 | 1996-07-09 | Kao Corp | 細胞接着抑制剤 |
CN1070372C (zh) * | 1995-02-15 | 2001-09-05 | 赵国强 | 强力抗癌膏及其制造方法 |
WO1997015575A1 (en) | 1995-10-27 | 1997-05-01 | Procyon Pharmaceuticals, Inc. | Protein kinase c modulators. y. |
CN1058620C (zh) | 1995-11-12 | 2000-11-22 | 卢颖 | 一种治疗癌症的外用中成药及配备生产工艺 |
JPH08268961A (ja) * | 1996-02-28 | 1996-10-15 | Procyon Pharmaceut Inc | 抗炎症組成物 |
US5932613A (en) * | 1996-07-03 | 1999-08-03 | Millennium Pharmaceuticals, Inc. | Anticancer agents |
AUPO864097A0 (en) | 1997-08-19 | 1997-09-11 | Peplin Pty Ltd | Anti-cancer compounds |
JP2001139468A (ja) | 1999-11-11 | 2001-05-22 | Lead Chemical Co Ltd | 抗ウイルス作用を有するホルボール誘導体 |
US6444555B2 (en) * | 1999-12-07 | 2002-09-03 | Advanced Micro Devices, Inc. | Method for establishing ultra-thin gate insulator using anneal in ammonia |
AUPQ801700A0 (en) | 2000-06-07 | 2000-06-29 | Peplin Research Pty Ltd | Enzyme and viral activation |
AUPQ923100A0 (en) | 2000-08-07 | 2000-08-31 | Peplin Research Pty Ltd | Treatment of prostate cancer |
US20030185168A1 (en) * | 2002-03-28 | 2003-10-02 | Yu-Wei Tung | Topology of frequency converting blocks of wireless lan access point |
-
1997
- 1997-08-19 AU AUPO8640A patent/AUPO864097A0/en not_active Abandoned
-
1998
- 1998-08-19 BR BR9811327-5A patent/BR9811327A/pt not_active Application Discontinuation
- 1998-08-19 WO PCT/AU1998/000656 patent/WO1999008994A1/en active IP Right Grant
- 1998-08-19 DE DE69839586T patent/DE69839586D1/de not_active Expired - Lifetime
- 1998-08-19 PT PT98938534T patent/PT1015413E/pt unknown
- 1998-08-19 CN CN98807751.5A patent/CN1266421B/zh not_active Expired - Lifetime
- 1998-08-19 HU HU0004262A patent/HU228862B1/hu active Protection Beyond IP Right Term
- 1998-08-19 EP EP98938534A patent/EP1015413B1/de not_active Expired - Lifetime
- 1998-08-19 JP JP2000509681A patent/JP2001515059A/ja not_active Withdrawn
- 1998-08-19 DK DK98938534T patent/DK1015413T3/da active
- 1998-08-19 AT AT98938534T patent/ATE397580T1/de active
- 1998-08-19 US US09/486,199 patent/US6432452B1/en not_active Expired - Lifetime
- 1998-08-19 ES ES98938534T patent/ES2308810T3/es not_active Expired - Lifetime
- 1998-08-19 CA CA002301082A patent/CA2301082C/en not_active Expired - Lifetime
-
2001
- 2001-06-21 US US09/888,178 patent/US6787161B2/en not_active Expired - Lifetime
- 2001-06-21 US US09/888,997 patent/US6844013B2/en not_active Expired - Lifetime
-
2004
- 2004-07-22 US US10/896,811 patent/US7410656B2/en not_active Expired - Lifetime
-
2008
- 2008-08-29 CY CY20081100929T patent/CY1108303T1/el unknown
-
2011
- 2011-11-14 JP JP2011249091A patent/JP2012031212A/ja active Pending
-
2013
- 2013-04-23 BE BE2013C026C patent/BE2013C026I2/fr unknown
- 2013-04-23 LU LU92185C patent/LU92185I2/xx unknown
- 2013-05-13 CY CY2013020C patent/CY2013020I2/el unknown
- 2013-10-30 HU HUS1300063 patent/HUS1300063I1/hu unknown
-
2014
- 2014-10-09 JP JP2014207764A patent/JP2015007130A/ja active Pending
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