DE69908819D1 - Glycopeptid-derivate und pharmazeutische zusammensetzungen, die sie enthalten - Google Patents

Glycopeptid-derivate und pharmazeutische zusammensetzungen, die sie enthalten

Info

Publication number
DE69908819D1
DE69908819D1 DE69908819T DE69908819T DE69908819D1 DE 69908819 D1 DE69908819 D1 DE 69908819D1 DE 69908819 T DE69908819 T DE 69908819T DE 69908819 T DE69908819 T DE 69908819T DE 69908819 D1 DE69908819 D1 DE 69908819D1
Authority
DE
Germany
Prior art keywords
pharmaceutical compositions
derivatives
glycopeptide
glycopeptide derivatives
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69908819T
Other languages
English (en)
Other versions
DE69908819T2 (de
Inventor
Kevin Judice
Ross Fatheree
M Lam
Michael Leadbetter
Sheringham Linsell
Yongqi Mu
Gary Trapp
Guang Yang
Yan Zhu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Innoviva Inc
Original Assignee
Theravance Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theravance Inc filed Critical Theravance Inc
Application granted granted Critical
Publication of DE69908819D1 publication Critical patent/DE69908819D1/de
Publication of DE69908819T2 publication Critical patent/DE69908819T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE69908819T 1998-12-23 1999-12-22 Glycopeptid-derivate und pharmazeutische zusammensetzungen, die sie enthalten Expired - Lifetime DE69908819T2 (de)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US11372898P 1998-12-23 1998-12-23
US113728P 1998-12-23
US12931399P 1999-04-14 1999-04-14
US129313P 1999-04-14
US16402499P 1999-11-04 1999-11-04
US164024P 1999-11-04
US16997899P 1999-12-10 1999-12-10
US169978P 1999-12-10
PCT/US1999/030543 WO2000039156A1 (en) 1998-12-23 1999-12-22 Glycopeptide derivatives and pharmaceutical compositions containing the same

Publications (2)

Publication Number Publication Date
DE69908819D1 true DE69908819D1 (de) 2003-07-17
DE69908819T2 DE69908819T2 (de) 2004-05-06

Family

ID=27493926

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69908819T Expired - Lifetime DE69908819T2 (de) 1998-12-23 1999-12-22 Glycopeptid-derivate und pharmazeutische zusammensetzungen, die sie enthalten

Country Status (23)

Country Link
US (9) US6392012B1 (de)
EP (1) EP1140993B1 (de)
JP (1) JP4362017B2 (de)
KR (1) KR100665204B1 (de)
CN (1) CN1249081C (de)
AT (1) ATE242783T1 (de)
AU (1) AU768204B2 (de)
BR (1) BRPI9914221B8 (de)
CA (1) CA2336445C (de)
CZ (1) CZ301184B6 (de)
DE (1) DE69908819T2 (de)
DK (1) DK1140993T3 (de)
ES (1) ES2201825T3 (de)
HK (1) HK1040721B (de)
HU (1) HU230190B1 (de)
IL (2) IL140093A0 (de)
NO (1) NO326066B1 (de)
NZ (1) NZ508594A (de)
PL (1) PL198311B1 (de)
PT (1) PT1140993E (de)
SI (1) SI1140993T1 (de)
WO (1) WO2000039156A1 (de)
ZA (1) ZA200007222B (de)

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CA2370782A1 (en) * 1999-04-02 2000-10-12 The Trustees Of Princeton University Desleucyl glycopeptide antibiotics and methods of making same
AU2001238020A1 (en) * 2000-02-04 2001-08-14 Advanced Medicine, Inc. Glycopeptide derivatives having antibiotic activity
SI1278549T1 (sl) * 2000-05-02 2009-04-30 Theravance Inc Sestavek, ki vsebuje ciklodekstrin in glikopeptidni antibiotik
WO2001083520A2 (en) * 2000-05-02 2001-11-08 Theravance,Inc Polyacid glycopeptide derivatives
JP4713810B2 (ja) 2000-05-02 2011-06-29 セラヴァンス， インコーポレーテッド グリコペプチドに対する還元的アルキル化プロセス
UA75083C2 (uk) 2000-06-22 2006-03-15 Тераванс, Інк. Похідні глікопептидфосфонатів
AU2001259816A1 (en) * 2000-06-22 2002-01-02 Advanced Medecine, Inc. Polyhydroxy glycopeptide derivatives
US6872804B2 (en) 2000-06-22 2005-03-29 Theravance, Inc. Glycopeptide disulfide and thioester derivatives
ES2302733T3 (es) * 2000-06-22 2008-08-01 Theravance, Inc. Derivados carboxi-sacaridos de glucopeptido.
US6905669B2 (en) * 2001-04-24 2005-06-14 Supergen, Inc. Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase
TWI275594B (en) * 2001-08-24 2007-03-11 Theravance Inc Process for preparing vancomycin phosphonate derivatives
TWI312785B (en) * 2001-08-24 2009-08-01 Theravance Inc Process for preparing vancomycin derivatives
ATE322975T1 (de) 2001-09-19 2006-04-15 Procter & Gamble Farbbedruckte mehrschichtstruktur, ein damit hergestellter absorbierender artikel und verfahren zu deren herstellung
TWI335332B (en) 2001-10-12 2011-01-01 Theravance Inc Cross-linked vancomycin-cephalosporin antibiotics
US20040033986A1 (en) 2002-05-17 2004-02-19 Protopopova Marina Nikolaevna Anti tubercular drug: compositions and methods
CN101404986B (zh) 2002-05-17 2011-09-28 赛奎拉公司 用于诊断和治疗感染性疾病的组合物和制药方法
US6878686B2 (en) 2002-05-24 2005-04-12 Theravance, Inc. Cross-linked glycopeptide-cephalosporin antibiotics
US6951963B2 (en) 2002-06-17 2005-10-04 Theravance, Inc. Process for preparing N-protected β-amino aldehyde compounds
AU2003248896B2 (en) * 2002-07-09 2010-04-22 Fasgen, Llc Methods of treating microbial infections in humans and animals
US20060074014A1 (en) * 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
WO2004046196A2 (en) * 2002-11-18 2004-06-03 Vicuron Pharmaceuticals Inc. Compositions and methods for treating bacterial infections with protein-dalbavancin complexes
JP2007500222A (ja) * 2003-05-23 2007-01-11 セラヴァンス インコーポレーテッド 架橋グリコペプチド−セファロスポリン抗生物質
DE602004012269T2 (de) * 2003-07-11 2009-04-30 Theravance, Inc., South San Francisco Quervernetzte glycopeptid-cephalosporin-antibiotika
DE102004055582A1 (de) 2004-11-18 2006-05-24 Bayer Cropscience Ag N-Heterocyclyl-phthalsäurediamide
EP1818340A4 (de) 2004-11-29 2009-02-25 Univ Nagoya Nat Univ Corp Antibiotische monomere glykopeptidderivate
US8304597B2 (en) 2004-12-15 2012-11-06 The Procter And Gamble Company Method of using an absorbent article having a functional enhancement indicator
US20070185015A1 (en) * 2005-02-28 2007-08-09 Chiron Corporation and North China Pharmaceutical Corporation Semi-synthetic desmethyl-vancomycin-based glycopeptides with antibiotic activity
US7368422B2 (en) * 2005-02-28 2008-05-06 Novartis Vaccines And Diagnostics Inc. Semi-synthetic rearranged vancomycin/desmethyl-vancomycin-based glycopeptides with antibiotic activity
US7632918B2 (en) * 2005-02-28 2009-12-15 Novartis Vaccines And Diagnostics, Inc. Semi-synthetic glycopeptides with antibiotic activity
WO2007035938A2 (en) 2005-09-22 2007-03-29 Medivas, Llc BIS-(α-AMINO)-DIOL-DIESTER-CONTAINING POLY(ESTER AMIDE) AND POLY(ESTER URETHANE) COMPOSITIONS AND METHODS OF USE
WO2007038246A2 (en) 2005-09-22 2007-04-05 Medivas, Llc Solid polymer delivery compositions and methods for use thereof
WO2007084507A2 (en) * 2006-01-13 2007-07-26 The Scripps Research Institute [ψ[CH2NH]PG4] GLYCOPEPTIDE ANTIBIOTIC ANALOGS
TW200808818A (en) * 2006-05-26 2008-02-16 Shionogi & Co Glycopeptide antibiotic derivatives
US8481696B2 (en) 2007-12-26 2013-07-09 Shionogi & Co., Ltd. Glycosylated glycopeptide antibiotic derivatives
AU2008343502A1 (en) * 2007-12-26 2009-07-09 Biomarin Pharmaceutical Inc. Novel semi-synthetic glycopeptides as antibacterial agents
WO2009123713A1 (en) 2008-04-01 2009-10-08 Cornell University Organo-soluble chitosan salts and chitosan-derived biomaterials prepared thereof
GB2465863A (en) * 2008-12-05 2010-06-09 Lead Therapeutics Inc Semi-synthetic heptapeptidic glycopeptides for the treatment of bacterial infections
CN101928330B (zh) * 2009-06-26 2013-10-16 上海来益生物药物研究开发中心有限责任公司 一种新的化合物及其应用
EP2688580A4 (de) * 2011-03-24 2015-03-25 Seachaid Pharmaceuticals Inc Vancomycinderivate
CA2925005A1 (en) * 2013-09-23 2015-03-26 Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) Vancomycin-sugar conjugates and uses thereof
EP3240574A1 (de) * 2014-12-25 2017-11-08 Jawaharlal Nehru Centre For Advanced Scientific Research Glykopeptide und verwendungen davon
CN109072271A (zh) * 2016-01-15 2018-12-21 汉堡大学 用于制备鼠李糖基化类黄酮的方法
JP2019511561A (ja) * 2016-01-28 2019-04-25 アカテコール・インコーポレイテッドＡＣａｔｅｃｈｏｌ， Ｉｎｃ． 光開裂性プライマー組成物および使用方法
CN107325159A (zh) * 2016-04-29 2017-11-07 中国科学院上海药物研究所 一类万古霉素衍生物、其制备方法、药物组合物和用途
JP7210476B2 (ja) 2017-05-22 2023-01-23 インスメッド インコーポレイテッド リポ‐グリコペプチド可切断性誘導体及びその使用
CN107987131B (zh) * 2017-11-16 2021-03-09 上海来益生物药物研究开发中心有限责任公司 一组具有抗耐药性细菌活性的化合物、其制备方法和应用
CN108409837B (zh) 2018-03-06 2021-09-24 上海来益生物药物研究开发中心有限责任公司 一组具有抗耐药性细菌活性的糖肽类化合物、其制备方法和应用
NL2023883B1 (en) * 2019-09-24 2021-04-26 Univ Leiden Antibiotic compounds
CN111620931B (zh) * 2020-06-12 2021-12-17 苏州博源医疗科技有限公司 万古霉素衍生物及其制备方法和应用
CN114213284B (zh) * 2022-01-04 2023-08-01 丽珠集团福州福兴医药有限公司 (9h-芴-9-基)-癸基(2-氧代乙基)氨基甲酸甲酯及其合成方法

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Also Published As

Publication number Publication date
SI1140993T1 (en) 2003-12-31
EP1140993B1 (de) 2003-06-11
US8030445B2 (en) 2011-10-04
US20060241024A1 (en) 2006-10-26
NO20006323D0 (no) 2000-12-12
US20050239690A1 (en) 2005-10-27
ATE242783T1 (de) 2003-06-15
US7723470B2 (en) 2010-05-25
HU230190B1 (hu) 2015-09-28
US20030060598A1 (en) 2003-03-27
KR20010085857A (ko) 2001-09-07
DE69908819T2 (de) 2004-05-06
HK1040721A1 (en) 2002-06-21
US6455669B1 (en) 2002-09-24
CA2336445C (en) 2011-07-19
NZ508594A (en) 2003-05-30
CA2336445A1 (en) 2000-07-06
ES2201825T3 (es) 2004-03-16
EP1140993A1 (de) 2001-10-10
CZ200122A3 (en) 2001-06-13
US20080103292A1 (en) 2008-05-01
NO20006323L (no) 2001-02-12
CN1315961A (zh) 2001-10-03
AU3127300A (en) 2000-07-31
HUP0400887A2 (hu) 2004-08-30
JP2002533472A (ja) 2002-10-08
BR9914221B1 (pt) 2013-12-31
NO326066B1 (no) 2008-09-08
CZ301184B6 (cs) 2009-12-02
US20090215982A1 (en) 2009-08-27
BRPI9914221B8 (pt) 2021-05-25
ZA200007222B (en) 2002-03-06
AU768204B2 (en) 2003-12-04
US7351791B2 (en) 2008-04-01
DK1140993T3 (da) 2003-10-06
CN1249081C (zh) 2006-04-05
US7101964B2 (en) 2006-09-05
PL198311B1 (pl) 2008-06-30
US20040204346A1 (en) 2004-10-14
HUP0400887A3 (en) 2012-09-28
JP4362017B2 (ja) 2009-11-11
IL140093A0 (en) 2002-02-10
BR9914221A (pt) 2001-06-26
HK1040721B (zh) 2003-10-17
PT1140993E (pt) 2003-10-31
WO2000039156A1 (en) 2000-07-06
KR100665204B1 (ko) 2007-01-04
US6962970B2 (en) 2005-11-08
US6949681B2 (en) 2005-09-27
IL140093A (en) 2006-06-11
US6392012B1 (en) 2002-05-21
US6444786B1 (en) 2002-09-03
PL348451A1 (en) 2002-05-20

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