DE69915858D1 - Mikrosphären aus polyvinylalkohol sowie verfahren zu deren herstellung - Google Patents
Mikrosphären aus polyvinylalkohol sowie verfahren zu deren herstellungInfo
- Publication number
- DE69915858D1 DE69915858D1 DE69915858T DE69915858T DE69915858D1 DE 69915858 D1 DE69915858 D1 DE 69915858D1 DE 69915858 T DE69915858 T DE 69915858T DE 69915858 T DE69915858 T DE 69915858T DE 69915858 D1 DE69915858 D1 DE 69915858D1
- Authority
- DE
- Germany
- Prior art keywords
- microspheres
- present
- relates
- production
- polyvinylalcohol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6927—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9813019A FR2784580B1 (fr) | 1998-10-16 | 1998-10-16 | Microspheres de polyvinyl-alcool et procedes de fabrication de celles-ci |
| FR9813019 | 1998-10-16 | ||
| PCT/EP1999/007846 WO2000023054A1 (en) | 1998-10-16 | 1999-10-15 | Polyvinyl alcohol microspheres, and methods for making and therapeutic uses of the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69915858D1 true DE69915858D1 (de) | 2004-04-29 |
| DE69915858T2 DE69915858T2 (de) | 2005-03-03 |
Family
ID=33462605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69915858T Expired - Lifetime DE69915858T2 (de) | 1998-10-16 | 1999-10-15 | Mikrosphären aus polyvinylalkohol sowie verfahren zu deren herstellung |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US6680046B1 (de) |
| EP (1) | EP1128816B1 (de) |
| JP (1) | JP4467799B2 (de) |
| AT (1) | ATE262319T1 (de) |
| AU (1) | AU1039600A (de) |
| CA (1) | CA2345205A1 (de) |
| DE (1) | DE69915858T2 (de) |
| ES (1) | ES2219072T3 (de) |
| FR (1) | FR2784580B1 (de) |
| WO (1) | WO2000023054A1 (de) |
Families Citing this family (124)
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| DE60139112D1 (de) * | 2000-03-06 | 2009-08-13 | Boston Scient Ltd | Unter ultralschall sichtbare embolisierende substanzen |
| US6652883B2 (en) | 2000-03-13 | 2003-11-25 | Biocure, Inc. | Tissue bulking and coating compositions |
| JP4871476B2 (ja) * | 2000-03-13 | 2012-02-08 | バイオコンパティブルズ ユーケー リミテッド | 塞栓組成物 |
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| EP1274472A2 (de) | 2000-03-20 | 2003-01-15 | Biosphere Medical, Inc. | Injizierbare und schwellfähige mikrokügelchen zur gewebeverstärkung |
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| US20030212022A1 (en) * | 2001-03-23 | 2003-11-13 | Jean-Marie Vogel | Compositions and methods for gene therapy |
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| US7053134B2 (en) * | 2002-04-04 | 2006-05-30 | Scimed Life Systems, Inc. | Forming a chemically cross-linked particle of a desired shape and diameter |
| WO2003105917A2 (en) * | 2002-06-12 | 2003-12-24 | Scimed Life Systems, Inc. | Bulking agents |
| US20080226723A1 (en) * | 2002-07-05 | 2008-09-18 | Celonova Biosciences, Inc. | Loadable Polymeric Particles for Therapeutic Use in Erectile Dysfunction and Methods of Preparing and Using the Same |
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| EP1578455A4 (de) * | 2002-11-04 | 2008-12-31 | Biosphere Medical Inc | Radioisotop-assoziierte polymerehydrogel-mikrokügelchen und verfahren zu ihrer herstellung und verwendung |
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-
1998
- 1998-10-16 FR FR9813019A patent/FR2784580B1/fr not_active Expired - Fee Related
-
1999
- 1999-10-15 AU AU10396/00A patent/AU1039600A/en not_active Abandoned
- 1999-10-15 ES ES99953858T patent/ES2219072T3/es not_active Expired - Lifetime
- 1999-10-15 AT AT99953858T patent/ATE262319T1/de not_active IP Right Cessation
- 1999-10-15 EP EP99953858A patent/EP1128816B1/de not_active Revoked
- 1999-10-15 DE DE69915858T patent/DE69915858T2/de not_active Expired - Lifetime
- 1999-10-15 JP JP2000576829A patent/JP4467799B2/ja not_active Expired - Lifetime
- 1999-10-15 CA CA002345205A patent/CA2345205A1/en not_active Abandoned
- 1999-10-15 US US09/419,114 patent/US6680046B1/en not_active Expired - Lifetime
- 1999-10-15 WO PCT/EP1999/007846 patent/WO2000023054A1/en active IP Right Grant
-
2003
- 2003-10-27 US US10/692,785 patent/US7591993B2/en not_active Expired - Fee Related
-
2009
- 2009-01-05 US US12/348,867 patent/US7670592B2/en not_active Expired - Fee Related
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2010
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Also Published As
| Publication number | Publication date |
|---|---|
| CA2345205A1 (en) | 2000-04-27 |
| US6680046B1 (en) | 2004-01-20 |
| FR2784580A1 (fr) | 2000-04-21 |
| FR2784580B1 (fr) | 2004-06-25 |
| EP1128816B1 (de) | 2004-03-24 |
| US20040091425A1 (en) | 2004-05-13 |
| ATE262319T1 (de) | 2004-04-15 |
| AU1039600A (en) | 2000-05-08 |
| JP4467799B2 (ja) | 2010-05-26 |
| EP1128816A1 (de) | 2001-09-05 |
| US8673266B2 (en) | 2014-03-18 |
| US20100119572A1 (en) | 2010-05-13 |
| WO2000023054A1 (en) | 2000-04-27 |
| US7670592B2 (en) | 2010-03-02 |
| DE69915858T2 (de) | 2005-03-03 |
| US20090117196A1 (en) | 2009-05-07 |
| ES2219072T3 (es) | 2004-11-16 |
| JP2002527206A (ja) | 2002-08-27 |
| US7591993B2 (en) | 2009-09-22 |
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