DE69922312D1 - Keramikmaterial zur Osteoinduktion enthaltend Mikroporen an der Öberfläche von Makroporen - Google Patents
Keramikmaterial zur Osteoinduktion enthaltend Mikroporen an der Öberfläche von MakroporenInfo
- Publication number
- DE69922312D1 DE69922312D1 DE69922312T DE69922312T DE69922312D1 DE 69922312 D1 DE69922312 D1 DE 69922312D1 DE 69922312 T DE69922312 T DE 69922312T DE 69922312 T DE69922312 T DE 69922312T DE 69922312 D1 DE69922312 D1 DE 69922312D1
- Authority
- DE
- Germany
- Prior art keywords
- macropores
- ceramic material
- osteoinduction
- containing micropores
- micropores
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229910010293 ceramic material Inorganic materials 0.000 title abstract 2
- 230000004819 osteoinduction Effects 0.000 title 1
- 239000012620 biological material Substances 0.000 abstract 2
- 230000002138 osteoinductive effect Effects 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C11/00—Multi-cellular glass ; Porous or hollow glass or glass particles
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C14/00—Glass compositions containing a non-glass component, e.g. compositions containing fibres, filaments, whiskers, platelets, or the like, dispersed in a glass matrix
- C03C14/004—Glass compositions containing a non-glass component, e.g. compositions containing fibres, filaments, whiskers, platelets, or the like, dispersed in a glass matrix the non-glass component being in the form of particles or flakes
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C4/00—Compositions for glass with special properties
- C03C4/0007—Compositions for glass with special properties for biologically-compatible glass
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B38/00—Porous mortars, concrete, artificial stone or ceramic ware; Preparation thereof
- C04B38/0051—Porous mortars, concrete, artificial stone or ceramic ware; Preparation thereof characterised by the pore size, pore shape or kind of porosity
- C04B38/0064—Multimodal pore size distribution
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B2111/00—Mortars, concrete or artificial stone or mixtures to prepare them, characterised by specific function, property or use
- C04B2111/00474—Uses not provided for elsewhere in C04B2111/00
- C04B2111/00836—Uses not provided for elsewhere in C04B2111/00 for medical or dental applications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/924—Material characteristic
- Y10S623/926—Synthetic
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP98203084 | 1998-09-15 | ||
EP98203084 | 1998-09-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69922312D1 true DE69922312D1 (de) | 2005-01-05 |
DE69922312T2 DE69922312T2 (de) | 2005-12-22 |
Family
ID=8234114
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69922312T Expired - Lifetime DE69922312T2 (de) | 1998-09-15 | 1999-09-14 | Keramikmaterial zur Osteoinduktion enthaltend Mikroporen an der Öberfläche von Makroporen |
Country Status (9)
Country | Link |
---|---|
US (2) | US6511510B1 (de) |
EP (1) | EP0987032B1 (de) |
JP (1) | JP2000093504A (de) |
AT (1) | ATE283713T1 (de) |
AU (1) | AU766735B2 (de) |
CA (1) | CA2282075A1 (de) |
DE (1) | DE69922312T2 (de) |
DK (1) | DK0987032T3 (de) |
ES (1) | ES2248958T3 (de) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040081704A1 (en) * | 1998-02-13 | 2004-04-29 | Centerpulse Biologics Inc. | Implantable putty material |
DE19940717A1 (de) | 1999-08-26 | 2001-03-01 | Gerontocare Gmbh | Resorblerbares Knochenersatz- und Knochenaufbaumaterial |
JP4809963B2 (ja) * | 1999-11-11 | 2011-11-09 | オリンパス株式会社 | 骨補填材 |
WO2002005862A1 (de) * | 2000-07-17 | 2002-01-24 | Dot Gmbh | Elektrochemisch abgeschiedene, bioaktive calciumphosphat-kompositschichten auf implantaten |
AU7571501A (en) * | 2000-08-04 | 2002-02-18 | Orthogem Ltd | Porous synthetic bone graft and method of manufacture thereof |
US20020114795A1 (en) * | 2000-12-22 | 2002-08-22 | Thorne Kevin J. | Composition and process for bone growth and repair |
US6949251B2 (en) * | 2001-03-02 | 2005-09-27 | Stryker Corporation | Porous β-tricalcium phosphate granules for regeneration of bone tissue |
JP5007476B2 (ja) * | 2001-03-23 | 2012-08-22 | オリンパス株式会社 | 人工骨材 |
WO2002083194A1 (en) * | 2001-04-12 | 2002-10-24 | Therics, Inc. | Method and apparatus for engineered regenerative biostructures |
US20050177238A1 (en) * | 2001-05-01 | 2005-08-11 | Khandkar Ashok C. | Radiolucent bone graft |
US7695521B2 (en) | 2001-05-01 | 2010-04-13 | Amedica Corporation | Hip prosthesis with monoblock ceramic acetabular cup |
US7776085B2 (en) * | 2001-05-01 | 2010-08-17 | Amedica Corporation | Knee prosthesis with ceramic tibial component |
AU2002324443A1 (en) * | 2001-06-14 | 2003-01-02 | Amedica Corporation | Metal-ceramic composite articulation |
TW200400062A (en) | 2002-04-03 | 2004-01-01 | Mathys Medizinaltechnik Ag | Kneadable, pliable bone replacement material |
WO2003092760A1 (de) | 2002-04-29 | 2003-11-13 | Biomet Deutschland Gmbh | Strukturierte komposite als matrix (scaffold) für das tissue engineering von knochen |
US7223414B1 (en) * | 2002-06-03 | 2007-05-29 | Ahmed El-Ghannam | Silica-calcium phosphate bioactive composite for improved synthetic graft resorbability and tissue regeneration |
DE10258773A1 (de) * | 2002-12-16 | 2004-07-08 | SDGI Holding, Inc., Wilmington | Knochenersatzmaterial |
WO2004058098A2 (en) * | 2002-12-17 | 2004-07-15 | Amedica Corporation | Total disc implant |
GB0311221D0 (en) * | 2003-05-15 | 2003-06-18 | Orthogem Ltd | Biomaterial |
DE10347232A1 (de) * | 2003-10-10 | 2005-05-12 | Bego Semados Gmbh & Co Kg | Anordnung zur Rückbildung eines parodontosebedingten Knochendefektes |
US20050085922A1 (en) * | 2003-10-17 | 2005-04-21 | Shappley Ben R. | Shaped filler for implantation into a bone void and methods of manufacture and use thereof |
JP4199653B2 (ja) * | 2003-12-09 | 2008-12-17 | 松崎 浩巳 | 骨補填材 |
US8128696B2 (en) * | 2005-05-11 | 2012-03-06 | Hermann Mayr | System and implant for ligament reconstruction or bone reconstruction |
CN103349793B (zh) | 2005-09-09 | 2016-02-10 | 阿格诺沃斯健康关爱公司 | 复合骨移植替代物水泥以及由其制得的制品 |
US8252058B2 (en) * | 2006-02-16 | 2012-08-28 | Amedica Corporation | Spinal implant with elliptical articulatory interface |
US20110020419A1 (en) * | 2006-02-17 | 2011-01-27 | Huipin Yuan | Osteoinductive calcium phosphates |
EP1829564A1 (de) * | 2006-02-17 | 2007-09-05 | Progentix B.V. i.o. | Osteoinduktives Kalziumphosphat |
US20070198093A1 (en) * | 2006-02-17 | 2007-08-23 | Amedica Corporation | Spinal implant with offset keels |
AU2007215625B2 (en) * | 2006-02-17 | 2012-06-28 | Progentix Orthobiology B.V. | Osteoinductive calcium phosphates |
KR100743182B1 (ko) * | 2006-09-11 | 2007-07-27 | 주식회사 메가젠 | 골 충진재 및 그 제조 방법 |
DE102006047248B4 (de) * | 2006-10-06 | 2012-05-31 | Celgen Ag | Dreidimensionale künstliche Kallusdistraktion |
US20080097618A1 (en) * | 2006-10-18 | 2008-04-24 | Kevin Charles Baker | Deposition of calcium-phosphate (CaP) and calcium-phosphate with bone morphogenic protein (CaP+BMP) coatings on metallic and polymeric surfaces |
US9439948B2 (en) * | 2006-10-30 | 2016-09-13 | The Regents Of The University Of Michigan | Degradable cage coated with mineral layers for spinal interbody fusion |
US7718616B2 (en) | 2006-12-21 | 2010-05-18 | Zimmer Orthobiologics, Inc. | Bone growth particles and osteoinductive composition thereof |
EP2014256A1 (de) * | 2007-07-12 | 2009-01-14 | Straumann Holding AG | Verbundmaterial zur Knochenreparatur |
US20090149569A1 (en) * | 2007-07-19 | 2009-06-11 | Shastri V Prasad | Surface engineering of tissue graft materials for enhanced porosity and cell adhesion |
WO2009089340A1 (en) | 2008-01-09 | 2009-07-16 | Innovative Health Technologies, Llc | Implant pellets and methods for performing bone augmentation and preservation |
GB0801935D0 (en) | 2008-02-01 | 2008-03-12 | Apatech Ltd | Porous biomaterial |
JP5382739B2 (ja) * | 2008-03-15 | 2014-01-08 | セルゲン エージー | 膨張剤及びシースを備える人工的な仮骨延長デバイス |
GB0813659D0 (en) * | 2008-07-25 | 2008-09-03 | Smith & Nephew | Fracture putty |
ES2804778T3 (es) * | 2009-07-23 | 2021-02-09 | Nuvasive Netherlands B V | Materiales cerámicos osteoinductivos moldeables e inyectables |
US9399086B2 (en) * | 2009-07-24 | 2016-07-26 | Warsaw Orthopedic, Inc | Implantable medical devices |
US8481065B2 (en) * | 2009-12-18 | 2013-07-09 | Howmedica Osteonics Corp. | Post irradiation shelf-stable dual paste direct injectable bone cement precursor systems and methods of making same |
ES2911190T3 (es) | 2010-05-11 | 2022-05-18 | Howmedica Osteonics Corp | Compuestos organofosforados, de metales multivalentes y composiciones y métodos de red interpenetrantes adhesivos poliméricos |
US8895291B2 (en) | 2010-10-08 | 2014-11-25 | Terumo Bct, Inc. | Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions |
EP2637983B1 (de) | 2010-11-10 | 2018-12-26 | Stryker European Holdings I, LLC | Verfahren zur herstellung eines polymeren knochenschaums |
CN103313733A (zh) | 2010-11-15 | 2013-09-18 | 捷迈整形外科生物材料有限公司 | 骨空隙填充剂 |
US8765189B2 (en) | 2011-05-13 | 2014-07-01 | Howmedica Osteonic Corp. | Organophosphorous and multivalent metal compound compositions and methods |
WO2013120217A1 (en) | 2012-02-14 | 2013-08-22 | Straumann Holding Ag | Bone repair material |
WO2013120214A1 (en) | 2012-02-14 | 2013-08-22 | Straumann Holding Ag | Bone repair material |
US9272072B1 (en) | 2012-10-19 | 2016-03-01 | Nuvasive, Inc. | Osteoinductive bone graft substitute |
NL2011195C2 (en) | 2013-07-18 | 2015-01-21 | Xpand Biotechnology B V | Method for producing an osteoinductive calcium phosphate and products thus obtained. |
CN105992816B (zh) | 2013-11-16 | 2018-04-17 | 泰尔茂比司特公司 | 生物反应器中的细胞扩增 |
JP6783143B2 (ja) | 2014-03-25 | 2020-11-11 | テルモ ビーシーティー、インコーポレーテッド | 培地の受動的補充 |
WO2016049421A1 (en) | 2014-09-26 | 2016-03-31 | Terumo Bct, Inc. | Scheduled feed |
WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
US10537658B2 (en) | 2017-03-28 | 2020-01-21 | DePuy Synthes Products, Inc. | Orthopedic implant having a crystalline gallium-containing hydroxyapatite coating and methods for making the same |
US10537661B2 (en) | 2017-03-28 | 2020-01-21 | DePuy Synthes Products, Inc. | Orthopedic implant having a crystalline calcium phosphate coating and methods for making the same |
EP3656842A1 (de) | 2017-03-31 | 2020-05-27 | Terumo BCT, Inc. | Zellexpansion |
US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
WO2019135216A1 (en) | 2018-01-02 | 2019-07-11 | Cartiheal (2009) Ltd. | Implantation tool and protocol for optimized solid substrates promoting cell and tissue growth |
KR102570214B1 (ko) * | 2021-08-30 | 2023-08-25 | 주식회사 에이치앤바이오 | 휘트록카이트를 포함하는 골이식재 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
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US4010242A (en) * | 1972-04-07 | 1977-03-01 | E. I. Dupont De Nemours And Company | Uniform oxide microspheres and a process for their manufacture |
US4073999A (en) * | 1975-05-09 | 1978-02-14 | Minnesota Mining And Manufacturing Company | Porous ceramic or metallic coatings and articles |
IL56141A (en) * | 1977-12-23 | 1981-10-30 | Sterling Drug Inc | Whitlockite ceramic and its manufacture |
DE3410650A1 (de) * | 1984-03-23 | 1985-10-03 | Kernforschungsanlage Jülich GmbH, 5170 Jülich | Mit mikroorganismen bewachsene poroese anorganische traeger, verfahren zur immobilisierung von mikroorganismen und dafuer geeignete traegerkoerper |
US4629464A (en) * | 1984-09-25 | 1986-12-16 | Tdk Corporation | Porous hydroxyapatite material for artificial bone substitute |
FR2577111B1 (fr) * | 1985-02-08 | 1987-05-22 | Christian Bailly | Machine pour le traitement des poireaux |
JPS63125259A (ja) * | 1986-11-14 | 1988-05-28 | 旭光学工業株式会社 | リン酸カルシウム系多孔質骨補填材 |
AU613387B2 (en) * | 1987-08-13 | 1991-08-01 | Carl-Zeiss-Stiftung Trading As Schott Glaswerke | An inorganic carrier element comprising an amine-containing surface layer for the immobilization of microorganisms or cells, a process for the preparation thereof |
JP2572606B2 (ja) * | 1987-09-14 | 1997-01-16 | 旭光学工業株式会社 | 表面多孔質なリン酸カルシウム系セラミックスの製造法 |
DE58906046D1 (de) * | 1989-07-22 | 1993-12-02 | Osborn Johannes Friedrich Prof | Osteotropes Implantatmaterial. |
US5266248A (en) * | 1990-05-10 | 1993-11-30 | Torao Ohtsuka | Method of producing hydroxylapatite base porous beads filler for an organism |
US5355898A (en) * | 1992-06-02 | 1994-10-18 | South African Medical Research Council | Method for inducing extraskeletal bone growth in primates and for screening implants therefor |
US5916553A (en) * | 1992-09-17 | 1999-06-29 | Schmidt; Karlheinz | Complex for inducing bone growth in the mastoid cavity |
FR2697243A1 (fr) * | 1992-10-26 | 1994-04-29 | Commissariat Energie Atomique | Procédé de préparation de pièces microporeuses en phosphate de calcium comprenant de l'hydroxylapatite, à microporosité contrôlée, et pièces obtenues par ce procédé. |
US5322821A (en) * | 1993-08-23 | 1994-06-21 | W. R. Grace & Co.-Conn. | Porous ceramic beads |
US5531794A (en) * | 1993-09-13 | 1996-07-02 | Asahi Kogaku Kogyo Kabushiki Kaisha | Ceramic device providing an environment for the promotion and formation of new bone |
JP3362267B2 (ja) * | 1993-12-29 | 2003-01-07 | 日本特殊陶業株式会社 | 生体インプラント材料及びその製造方法 |
US5626861A (en) * | 1994-04-01 | 1997-05-06 | Massachusetts Institute Of Technology | Polymeric-hydroxyapatite bone composite |
US6149688A (en) * | 1995-06-07 | 2000-11-21 | Surgical Dynamics, Inc. | Artificial bone graft implant |
-
1999
- 1999-09-09 AU AU47463/99A patent/AU766735B2/en not_active Ceased
- 1999-09-10 CA CA002282075A patent/CA2282075A1/en not_active Abandoned
- 1999-09-14 AT AT99202992T patent/ATE283713T1/de not_active IP Right Cessation
- 1999-09-14 DE DE69922312T patent/DE69922312T2/de not_active Expired - Lifetime
- 1999-09-14 EP EP99202992A patent/EP0987032B1/de not_active Expired - Lifetime
- 1999-09-14 JP JP11261019A patent/JP2000093504A/ja active Pending
- 1999-09-14 DK DK99202992T patent/DK0987032T3/da active
- 1999-09-14 ES ES99202992T patent/ES2248958T3/es not_active Expired - Lifetime
- 1999-09-15 US US09/396,072 patent/US6511510B1/en not_active Expired - Lifetime
-
2001
- 2001-11-15 US US09/999,029 patent/US20020035402A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU766735B2 (en) | 2003-10-23 |
EP0987032B1 (de) | 2004-12-01 |
US20020035402A1 (en) | 2002-03-21 |
US6511510B1 (en) | 2003-01-28 |
ATE283713T1 (de) | 2004-12-15 |
DE69922312T2 (de) | 2005-12-22 |
DK0987032T3 (da) | 2005-03-21 |
CA2282075A1 (en) | 2000-03-15 |
ES2248958T3 (es) | 2006-03-16 |
JP2000093504A (ja) | 2000-04-04 |
EP0987032A1 (de) | 2000-03-22 |
AU4746399A (en) | 2000-03-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |