DE69928111D1 - Vorrichtung und verfahren zur dreidimensionalen ionenspeicherung unter atmosphärendruck - Google Patents
Vorrichtung und verfahren zur dreidimensionalen ionenspeicherung unter atmosphärendruckInfo
- Publication number
- DE69928111D1 DE69928111D1 DE69928111T DE69928111T DE69928111D1 DE 69928111 D1 DE69928111 D1 DE 69928111D1 DE 69928111 T DE69928111 T DE 69928111T DE 69928111 T DE69928111 T DE 69928111T DE 69928111 D1 DE69928111 D1 DE 69928111D1
- Authority
- DE
- Germany
- Prior art keywords
- ions
- gas
- analyzer region
- atmospheric pressure
- dimensional space
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
- G01N27/622—Ion mobility spectrometry
- G01N27/624—Differential mobility spectrometry [DMS]; Field asymmetric-waveform ion mobility spectrometry [FAIMS]
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D59/00—Separation of different isotopes of the same chemical element
- B01D59/44—Separation by mass spectrography
- B01D59/46—Separation by mass spectrography using only electrostatic fields
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D59/00—Separation of different isotopes of the same chemical element
- B01D59/44—Separation by mass spectrography
- B01D59/48—Separation by mass spectrography using electrostatic and magnetic fields
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
- H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
- H01J49/044—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples with means for preventing droplets from entering the analyzer; Desolvation of droplets
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9548198P | 1998-08-05 | 1998-08-05 | |
US95481P | 1998-08-05 | ||
CA2260572 | 1999-01-29 | ||
CA002260572A CA2260572A1 (en) | 1998-08-05 | 1999-01-29 | Apparatus and method for atmospheric pressure 3-dimensional ion trapping |
US321820 | 1999-05-28 | ||
US09/321,820 US6504149B2 (en) | 1998-08-05 | 1999-05-28 | Apparatus and method for desolvating and focussing ions for introduction into a mass spectrometer |
PCT/CA1999/000718 WO2000008457A1 (en) | 1998-08-05 | 1999-08-05 | Apparatus and method for atmospheric pressure 3-dimensional ion trapping |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69928111D1 true DE69928111D1 (de) | 2005-12-08 |
DE69928111T2 DE69928111T2 (de) | 2006-07-27 |
Family
ID=42298131
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69928111T Expired - Lifetime DE69928111T2 (de) | 1998-08-05 | 1999-08-05 | Vorrichtung und verfahren zur dreidimensionalen ionenspeicherung unter atmosphärendruck |
DE69927983T Expired - Lifetime DE69927983T2 (de) | 1998-08-05 | 1999-08-05 | Verfahren zur trennung und anreicherung von isotopen in der gasphase |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69927983T Expired - Lifetime DE69927983T2 (de) | 1998-08-05 | 1999-08-05 | Verfahren zur trennung und anreicherung von isotopen in der gasphase |
Country Status (6)
Country | Link |
---|---|
EP (3) | EP1102985B8 (de) |
JP (2) | JP2002522873A (de) |
AT (2) | ATE308751T1 (de) |
AU (4) | AU5144399A (de) |
DE (2) | DE69928111T2 (de) |
WO (4) | WO2000008457A1 (de) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6498342B1 (en) * | 1997-06-02 | 2002-12-24 | Advanced Research & Technology Institute | Ion separation instrument |
WO2000063949A1 (en) * | 1999-04-16 | 2000-10-26 | Mds Inc. | Mass spectrometer, including coupling of an atmospheric pressure ion source to a low pressure mass analyzer |
US6806463B2 (en) | 1999-07-21 | 2004-10-19 | The Charles Stark Draper Laboratory, Inc. | Micromachined field asymmetric ion mobility filter and detection system |
US6690004B2 (en) | 1999-07-21 | 2004-02-10 | The Charles Stark Draper Laboratory, Inc. | Method and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry |
US6512224B1 (en) | 1999-07-21 | 2003-01-28 | The Charles Stark Draper Laboratory, Inc. | Longitudinal field driven field asymmetric ion mobility filter and detection system |
US7005632B2 (en) | 2002-04-12 | 2006-02-28 | Sionex Corporation | Method and apparatus for control of mobility-based ion species identification |
US6495823B1 (en) | 1999-07-21 | 2002-12-17 | The Charles Stark Draper Laboratory, Inc. | Micromachined field asymmetric ion mobility filter and detection system |
US7148477B2 (en) | 1999-07-21 | 2006-12-12 | Sionex Corporation | System for trajectory-based ion species identification |
US6815668B2 (en) | 1999-07-21 | 2004-11-09 | The Charles Stark Draper Laboratory, Inc. | Method and apparatus for chromatography-high field asymmetric waveform ion mobility spectrometry |
US7399958B2 (en) | 1999-07-21 | 2008-07-15 | Sionex Corporation | Method and apparatus for enhanced ion mobility based sample analysis using various analyzer configurations |
US6815669B1 (en) | 1999-07-21 | 2004-11-09 | The Charles Stark Draper Laboratory, Inc. | Longitudinal field driven ion mobility filter and detection system |
US7098449B1 (en) | 1999-07-21 | 2006-08-29 | The Charles Stark Draper Laboratory, Inc. | Spectrometer chip assembly |
US7129482B2 (en) | 1999-07-21 | 2006-10-31 | Sionex Corporation | Explosives detection using differential ion mobility spectrometry |
US7057168B2 (en) | 1999-07-21 | 2006-06-06 | Sionex Corporation | Systems for differential ion mobility analysis |
US7164122B2 (en) | 2000-02-29 | 2007-01-16 | Ionwerks, Inc. | Ion mobility spectrometer |
AU2001247243A1 (en) | 2000-02-29 | 2001-09-12 | Ionwerks, Inc. | Improved mobility spectrometer |
CA2401772C (en) * | 2000-03-14 | 2009-11-24 | National Research Council Of Canada | Tandem high field asymmetric waveform ion mobility spectrometry (faims)/ion mobility spectrometry |
AU2001239073B2 (en) * | 2000-03-14 | 2005-01-06 | National Research Council Canada | Faims apparatus and method with laser-based ionization source |
AU782410B2 (en) * | 2000-03-14 | 2005-07-28 | National Research Council Of Canada | Improved parallel plate geometry faims apparatus and method |
JP4578613B2 (ja) * | 2000-04-03 | 2010-11-10 | キヤノンアネルバ株式会社 | Qポール型質量分析計 |
US7375319B1 (en) | 2000-06-09 | 2008-05-20 | Willoughby Ross C | Laser desorption ion source |
WO2002083276A1 (en) * | 2001-04-17 | 2002-10-24 | The Charles Stark Draper Laboratory, Inc. | Methods and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry |
US6784424B1 (en) | 2001-05-26 | 2004-08-31 | Ross C Willoughby | Apparatus and method for focusing and selecting ions and charged particles at or near atmospheric pressure |
DE10125907A1 (de) * | 2001-05-28 | 2002-12-12 | Michael Karas | Separation von chiralen Substanzen in einem Ionenmobilitätsspektrometer durch Zuführung selektiv wechselwirkender Kollisionsgase |
CA2391060C (en) * | 2001-06-21 | 2011-08-09 | Micromass Limited | Mass spectrometer |
US7586088B2 (en) | 2001-06-21 | 2009-09-08 | Micromass Uk Limited | Mass spectrometer and method of mass spectrometry |
US7119328B2 (en) | 2001-06-30 | 2006-10-10 | Sionex Corporation | System for DMS peak resolution |
EP2386852B1 (de) | 2001-06-30 | 2019-08-28 | DH Technologies Development Pte. Ltd. | Identifizierung unbekannter Substanzen mithilfe eines "field asymmetric waveform"-Ionenmobilitätsspektrometers (FAIMS), das eine simultane Detektion von positiven und negativen Ionen ermöglicht |
US7274015B2 (en) | 2001-08-08 | 2007-09-25 | Sionex Corporation | Capacitive discharge plasma ion source |
US7091481B2 (en) | 2001-08-08 | 2006-08-15 | Sionex Corporation | Method and apparatus for plasma generation |
US6727496B2 (en) | 2001-08-14 | 2004-04-27 | Sionex Corporation | Pancake spectrometer |
WO2003067244A2 (en) | 2002-02-08 | 2003-08-14 | Ionalytics Corporation | Faims with non-destructive detection of selectively transmitted ions |
US7034286B2 (en) | 2002-02-08 | 2006-04-25 | Ionalytics Corporation | FAIMS apparatus having plural ion inlets and method therefore |
US7122794B1 (en) | 2002-02-21 | 2006-10-17 | Sionex Corporation | Systems and methods for ion mobility control |
US6624410B1 (en) * | 2002-02-25 | 2003-09-23 | Monitor Instruments Company, Llc | Cycloidal mass spectrometer |
US6906319B2 (en) | 2002-05-17 | 2005-06-14 | Micromass Uk Limited | Mass spectrometer |
US7095019B1 (en) | 2003-05-30 | 2006-08-22 | Chem-Space Associates, Inc. | Remote reagent chemical ionization source |
US6831273B2 (en) * | 2002-07-31 | 2004-12-14 | General Electric Company | Ion mobility spectrometers with improved resolution |
CA2484125C (en) | 2002-09-03 | 2012-04-10 | Micromass Uk Limited | Mass spectrometer |
AU2003298597A1 (en) | 2002-10-12 | 2004-05-25 | Sionex Corporation | NOx MONITOR USING DIFFERENTIAL MOBILITY SPECTROMETRY |
CA2521099A1 (en) * | 2003-04-09 | 2004-10-28 | Brigham Young University | Cross-flow ion mobility analyzer |
EP1651949A4 (de) * | 2003-06-20 | 2010-01-20 | Univ Brigham Young | Einzelvorrichtung zur ionenmobilitäts- und ionenfallen-massenspektrometrie |
EP1668298A4 (de) | 2003-09-17 | 2010-04-14 | Sionex Corp | Festkörperströmungsgenerator und verwandte systeme, anwendungen und verfahren |
WO2005052546A2 (en) | 2003-11-25 | 2005-06-09 | Sionex Corporation | Mobility bases apparatus and methods using dispersion characteristics to improve analysis of a sample |
CA2550088A1 (en) | 2003-12-18 | 2005-07-07 | Sionex Corporation | Methods and apparatus for enhanced ion based sample detection using selective pre-separation and amplification |
CA2554997A1 (en) | 2004-02-02 | 2005-08-18 | Sionex Corporation | Compact sample analysis systems and related methods using combined chromatography and mobility spectrometry techniques |
EP1756561A1 (de) | 2004-04-28 | 2007-02-28 | Sionex Corporation | System und verfahren zur ionenspeziesanalyse mit verbesserter zustandskontrolle und dateninterpretation unter verwendung differentieller mobilitätsspektrometer |
GB0424426D0 (en) | 2004-11-04 | 2004-12-08 | Micromass Ltd | Mass spectrometer |
WO2006060807A1 (en) | 2004-12-03 | 2006-06-08 | Sionex Corporation | Method and apparatus for enhanced ion based sample filtering and detection |
WO2006119167A1 (en) | 2005-04-29 | 2006-11-09 | Sionex Corporation | Compact gas chromatography and ion mobility based sample analysis systems, methods, and devices |
US7351960B2 (en) | 2005-05-16 | 2008-04-01 | Thermo Finnigan Llc | Enhanced ion desolvation for an ion mobility spectrometry device |
US20110036973A1 (en) * | 2005-09-19 | 2011-02-17 | Owlstone Ltd | Ion pump |
GB0522933D0 (en) * | 2005-11-10 | 2005-12-21 | Micromass Ltd | Mass spectrometer |
JP2007220488A (ja) * | 2006-02-16 | 2007-08-30 | Tokyo Gas Co Ltd | プラズマ放電装置および排気ガス処理装置 |
US7339166B2 (en) | 2006-02-24 | 2008-03-04 | Battelle Memorial Institute | Interface and process for enhanced transmission of non-circular ion beams between stages at unequal pressure |
US8563322B2 (en) | 2006-04-20 | 2013-10-22 | Axel Mie | Method for separation of molecules |
CA2685169C (en) | 2007-02-01 | 2016-12-13 | Sionex Corporation | Differential mobility spectrometer pre-filter assembly for a mass spectrometer |
JP4905270B2 (ja) * | 2007-06-29 | 2012-03-28 | 株式会社日立製作所 | イオントラップ、質量分析計、イオンモビリティ分析計 |
US8173959B1 (en) | 2007-07-21 | 2012-05-08 | Implant Sciences Corporation | Real-time trace detection by high field and low field ion mobility and mass spectrometry |
JP5323384B2 (ja) * | 2008-04-14 | 2013-10-23 | 株式会社日立製作所 | 質量分析計および質量分析方法 |
WO2009143616A1 (en) * | 2008-05-30 | 2009-12-03 | Mds Analytical Technologies, A Business Unit Of Mds Inc., Doing Business Through Its Sciex Division | Method and system for providing a modifier to a curtain gas for a differential mobility spectrometer |
CA2720244C (en) * | 2008-05-30 | 2018-02-27 | Dh Technologies Development Pte. Ltd. | Method and system for vacuum driven differential mobility spectrometer/mass spectrometer interface with adjustable resolution and selectivity |
US8237118B2 (en) | 2008-08-21 | 2012-08-07 | University Of Florida Research Foundation, Inc. | Partial ovoidal FAIMS electrode |
US9330896B2 (en) | 2012-09-25 | 2016-05-03 | Yoshinori Sano | Mass analysis device and mass separation device |
GB2549248B (en) | 2016-01-12 | 2020-07-22 | Thermo Fisher Scient Bremen Gmbh | IRMS sample introduction system and method |
JP6330154B2 (ja) * | 2016-05-24 | 2018-05-30 | パナソニックIpマネジメント株式会社 | 電界非対称性イオン移動度分光計、およびそれを用いた混合物分離方法 |
CN108899264B (zh) * | 2018-06-07 | 2020-01-31 | 中国科学院合肥物质科学研究院 | 一种高灵敏高场不对称波形离子迁移谱检测装置 |
GB201810273D0 (en) | 2018-06-22 | 2018-08-08 | Thermo Fisher Scient Bremen Gmbh | Structural analysis of ionised molecules |
US11092569B1 (en) | 2020-07-05 | 2021-08-17 | Cannabix Technologies Inc. | Apparatus and methods for detection of molecules |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5521380A (en) * | 1992-05-29 | 1996-05-28 | Wells; Gregory J. | Frequency modulated selected ion species isolation in a quadrupole ion trap |
US5420424A (en) * | 1994-04-29 | 1995-05-30 | Mine Safety Appliances Company | Ion mobility spectrometer |
US5729014A (en) * | 1996-07-11 | 1998-03-17 | Varian Associates, Inc. | Method for injection of externally produced ions into a quadrupole ion trap |
JP3386048B2 (ja) * | 2000-12-14 | 2003-03-10 | 株式会社島津製作所 | イオントラップ型質量分析装置 |
-
1999
- 1999-08-05 WO PCT/CA1999/000718 patent/WO2000008457A1/en active IP Right Grant
- 1999-08-05 EP EP99936210A patent/EP1102985B8/de not_active Expired - Lifetime
- 1999-08-05 AU AU51443/99A patent/AU5144399A/en not_active Abandoned
- 1999-08-05 DE DE69928111T patent/DE69928111T2/de not_active Expired - Lifetime
- 1999-08-05 JP JP2000564041A patent/JP2002522873A/ja active Pending
- 1999-08-05 AU AU51441/99A patent/AU5144199A/en not_active Abandoned
- 1999-08-05 WO PCT/CA1999/000715 patent/WO2000008455A1/en active Application Filing
- 1999-08-05 AT AT99936212T patent/ATE308751T1/de not_active IP Right Cessation
- 1999-08-05 EP EP99936208A patent/EP1102984A1/de not_active Ceased
- 1999-08-05 EP EP99936212A patent/EP1102986B8/de not_active Expired - Lifetime
- 1999-08-05 WO PCT/CA1999/000716 patent/WO2000008456A1/en active IP Right Grant
- 1999-08-05 AU AU51440/99A patent/AU5144099A/en not_active Abandoned
- 1999-08-05 WO PCT/CA1999/000714 patent/WO2000008454A1/en not_active Application Discontinuation
- 1999-08-05 AU AU51439/99A patent/AU5143999A/en not_active Abandoned
- 1999-08-05 DE DE69927983T patent/DE69927983T2/de not_active Expired - Lifetime
- 1999-08-05 AT AT99936210T patent/ATE308043T1/de not_active IP Right Cessation
-
2009
- 2009-12-21 JP JP2009289543A patent/JP4990348B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE308751T1 (de) | 2005-11-15 |
JP4990348B2 (ja) | 2012-08-01 |
EP1102986A1 (de) | 2001-05-30 |
DE69927983T2 (de) | 2006-08-24 |
AU5144199A (en) | 2000-02-28 |
EP1102985B8 (de) | 2006-04-26 |
EP1102984A1 (de) | 2001-05-30 |
JP2010108941A (ja) | 2010-05-13 |
WO2000008456A1 (en) | 2000-02-17 |
AU5143999A (en) | 2000-02-28 |
JP2002522873A (ja) | 2002-07-23 |
AU5144399A (en) | 2000-02-28 |
AU5144099A (en) | 2000-02-28 |
EP1102985A1 (de) | 2001-05-30 |
EP1102986B1 (de) | 2005-11-02 |
WO2000008454A1 (en) | 2000-02-17 |
WO2000008457A1 (en) | 2000-02-17 |
WO2000008455A1 (en) | 2000-02-17 |
DE69928111T2 (de) | 2006-07-27 |
ATE308043T1 (de) | 2005-11-15 |
EP1102985B1 (de) | 2005-10-26 |
DE69927983D1 (de) | 2005-12-01 |
EP1102986B8 (de) | 2006-01-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: NATIONAL RESEARCH COUNCIL CANADA, OTTAWA, ONTARIO, |
|
8364 | No opposition during term of opposition |