DE809911T1 - Verfahren und vorrichtung zur schnellen erfassung von fokussierten mikroskopbildern - Google Patents

Verfahren und vorrichtung zur schnellen erfassung von fokussierten mikroskopbildern

Info

Publication number
DE809911T1
DE809911T1 DE0809911T DE95930866T DE809911T1 DE 809911 T1 DE809911 T1 DE 809911T1 DE 0809911 T DE0809911 T DE 0809911T DE 95930866 T DE95930866 T DE 95930866T DE 809911 T1 DE809911 T1 DE 809911T1
Authority
DE
Germany
Prior art keywords
microscope images
fast detection
focused microscope
focused
fast
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE0809911T
Other languages
English (en)
Inventor
Jon Hayenga
Louis Piloco
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neopath Inc
Original Assignee
Neopath Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neopath Inc filed Critical Neopath Inc
Publication of DE809911T1 publication Critical patent/DE809911T1/de
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T1/00General purpose image data processing
    • G06T1/60Memory management
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/24Base structure
    • G02B21/26Stages; Adjusting means therefor
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/36Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365Control or image processing arrangements for digital or video microscopes
    • G02B21/367Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04NPICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N23/00Cameras or camera modules comprising electronic image sensors; Control thereof
    • H04N23/60Control of cameras or camera modules
    • H04N23/67Focus control based on electronic image sensor signals
    • H04N23/673Focus control based on electronic image sensor signals based on contrast or high frequency components of image signals, e.g. hill climbing method
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04NPICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N23/00Cameras or camera modules comprising electronic image sensors; Control thereof
    • H04N23/70Circuitry for compensating brightness variation in the scene
    • H04N23/74Circuitry for compensating brightness variation in the scene by influencing the scene brightness using illuminating means
DE0809911T 1994-09-07 1995-08-21 Verfahren und vorrichtung zur schnellen erfassung von fokussierten mikroskopbildern Pending DE809911T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/302,355 US5912699A (en) 1992-02-18 1994-09-07 Method and apparatus for rapid capture of focused microscopic images
PCT/US1995/010588 WO1996008106A1 (en) 1994-09-07 1995-08-21 Method and apparatus for rapid capture of focused microscopic images

Publications (1)

Publication Number Publication Date
DE809911T1 true DE809911T1 (de) 1998-11-19

Family

ID=23167407

Family Applications (1)

Application Number Title Priority Date Filing Date
DE0809911T Pending DE809911T1 (de) 1994-09-07 1995-08-21 Verfahren und vorrichtung zur schnellen erfassung von fokussierten mikroskopbildern

Country Status (8)

Country Link
US (1) US5912699A (de)
EP (1) EP0809911A4 (de)
JP (1) JPH10505721A (de)
AU (1) AU703583B2 (de)
CA (1) CA2199407C (de)
DE (1) DE809911T1 (de)
ES (1) ES2123471T1 (de)
WO (1) WO1996008106A1 (de)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1172717A (ja) * 1997-08-29 1999-03-16 Nikon Corp 顕微鏡デジタル写真撮影システム
US6753919B1 (en) * 1998-11-25 2004-06-22 Iridian Technologies, Inc. Fast focus assessment system and method for imaging
US7034883B1 (en) 1999-08-10 2006-04-25 Cellavision Ab Automatic focusing
US6137967A (en) 1999-09-13 2000-10-24 Oce Printing Systems Gmbh Document verification and tracking system for printed material
US6665060B1 (en) 1999-10-29 2003-12-16 Cytyc Corporation Cytological imaging system and method
US7738688B2 (en) 2000-05-03 2010-06-15 Aperio Technologies, Inc. System and method for viewing virtual slides
US7668362B2 (en) * 2000-05-03 2010-02-23 Aperio Technologies, Inc. System and method for assessing virtual slide image quality
US6711283B1 (en) 2000-05-03 2004-03-23 Aperio Technologies, Inc. Fully automatic rapid microscope slide scanner
US7518652B2 (en) * 2000-05-03 2009-04-14 Aperio Technologies, Inc. Method and apparatus for pre-focus in a linear array based slide scanner
US7155049B2 (en) * 2001-01-11 2006-12-26 Trestle Acquisition Corp. System for creating microscopic digital montage images
US6798571B2 (en) 2001-01-11 2004-09-28 Interscope Technologies, Inc. System for microscopic digital montage imaging using a pulse light illumination system
US6993169B2 (en) * 2001-01-11 2006-01-31 Trestle Corporation System and method for finding regions of interest for microscopic digital montage imaging
CA2436219C (en) * 2001-03-03 2012-05-15 Optimum Power Technology, L.P. Apparatus and method for adjusting filter frequency in relation to sampling frequency
DE10156275B4 (de) * 2001-11-16 2006-08-03 Leo Elektronenmikroskopie Gmbh Detektoranordnung und Detektionsverfahren
JP4021183B2 (ja) * 2001-11-29 2007-12-12 オリンパス株式会社 合焦状態信号出力装置
US7538815B1 (en) * 2002-01-23 2009-05-26 Marena Systems Corporation Autofocus system and method using focus measure gradient
US7257268B2 (en) 2003-02-28 2007-08-14 Aperio Technologies, Inc. Systems and methods for image pattern recognition
US7116440B2 (en) 2003-02-28 2006-10-03 Aperio Technologies, Inc. Image processing and analysis framework
JP2007516009A (ja) * 2003-10-03 2007-06-21 アカデミッシュ メディシュ セントラム 基質の反射の画像処理のためのシステム及び方法。
JP5134365B2 (ja) 2004-05-27 2013-01-30 アペリオ・テクノロジーズ・インコーポレイテッド 三次元仮想スライドを生成しかつ可視化するためのシステム及び方法
GB0414201D0 (en) * 2004-06-24 2004-07-28 Fujifilm Electronic Imaging Method and apparatus for forming a multiple focus stack image
DE102004042913A1 (de) * 2004-09-02 2006-03-30 Westfälische-Wilhelms Universität Münster Scanneranordnung und Verfahren zum optischen Abtasten eines Objektes
US9131861B2 (en) * 2004-11-30 2015-09-15 Academisch Medisch Centrum Pulsed lighting imaging systems and methods
WO2006081362A2 (en) 2005-01-27 2006-08-03 Aperio Technologies, Inc Systems and methods for viewing three dimensional virtual slides
GB0503032D0 (en) * 2005-02-14 2005-03-23 Fujifilm Electronic Imaging Blip focus
US7417213B2 (en) * 2005-06-22 2008-08-26 Tripath Imaging, Inc. Apparatus and method for rapid microscopic image focusing having a movable objective
US8164622B2 (en) * 2005-07-01 2012-04-24 Aperio Technologies, Inc. System and method for single optical axis multi-detector microscope slide scanner
EP2036003B1 (de) 2006-06-30 2017-05-03 Leica Biosystems Imaging, Inc. Verfahren zum speichern und abrufen von grossen bilder mittels dicom
US8010555B2 (en) * 2006-06-30 2011-08-30 Aperio Technologies, Inc. System and method for managing images over a network
JP4758331B2 (ja) * 2006-12-08 2011-08-24 オリンパス株式会社 顕微鏡用撮像装置および顕微鏡用撮像プログラム
JP5389016B2 (ja) 2007-05-04 2014-01-15 アペリオ・テクノロジーズ・インコーポレイテッド 病理学における品質保証のためのシステムおよび方法
US8878923B2 (en) * 2007-08-23 2014-11-04 General Electric Company System and method for enhanced predictive autofocusing
CN101939616B (zh) * 2008-01-09 2014-07-09 株式会社尼康 测量设备和测量方法
US7706632B2 (en) * 2008-01-17 2010-04-27 Ffei Limited Method and apparatus for forming a multiple focus stack image
US7645971B2 (en) * 2008-01-18 2010-01-12 Ffei Limited Image scanning apparatus and method
US8743195B2 (en) 2008-10-24 2014-06-03 Leica Biosystems Imaging, Inc. Whole slide fluorescence scanner
EP2405647B1 (de) * 2009-03-03 2019-06-12 Panasonic Corporation Bildgebungsgerät mit blitzeffektkorrektur
US20110090327A1 (en) * 2009-10-15 2011-04-21 General Electric Company System and method for imaging with enhanced depth of field
US8314837B2 (en) * 2009-10-15 2012-11-20 General Electric Company System and method for imaging with enhanced depth of field
US20110091125A1 (en) * 2009-10-15 2011-04-21 General Electric Company System and method for imaging with enhanced depth of field
AU2010308550B2 (en) 2009-10-19 2013-05-23 Ventana Medical Systems, Inc. Imaging system and techniques
WO2011072211A2 (en) 2009-12-11 2011-06-16 Aperio Technologies, Inc. Improved signal to noise ratio in digital pathology image analysis
DE102011075369B4 (de) 2011-05-05 2022-02-17 Carl Zeiss Microscopy Gmbh Verfahren und Vorrichtung zur Objektabbildung
GB2505691B (en) * 2012-09-07 2018-02-21 Ffei Ltd Method and apparatus for image scanning
GB201409203D0 (en) 2014-05-23 2014-07-09 Ffei Ltd Improvements in digitising slides
GB201409202D0 (en) 2014-05-23 2014-07-09 Ffei Ltd Improvements in imaging microscope samples
JP2017526507A (ja) 2014-08-31 2017-09-14 ベレシュトカ,ジョン 目を解析するためのシステム及び方法
CN104394323B (zh) * 2014-12-04 2018-07-24 厦门大学 一种放大显微图像的拍摄方法
FI20175410A (fi) * 2017-05-08 2018-11-09 Grundium Oy Laite ja menetelmä mikroskooppileikkeiden skannaamiseksi
US10409141B2 (en) * 2017-09-20 2019-09-10 Qualcomm Incorporated System and method for improved camera flash
CN108345101A (zh) * 2018-01-16 2018-07-31 迪瑞医疗科技股份有限公司 照明系统及其用于运动细胞拍摄照明的方法
EP3611912B1 (de) * 2018-08-15 2022-11-23 reflecta GmbH Diascanner

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3629499A (en) * 1969-07-02 1971-12-21 Philips Corp Pattern noise reduction system
CH518562A (de) * 1970-02-24 1972-01-31 Zeiss Carl Fa Verfahren und Vorrichtung zur automatischen Fokussierung von Mikroskopen
US3800078A (en) * 1972-12-18 1974-03-26 Ibm Digitally compensated scanning system
GB1460433A (en) * 1973-04-06 1977-01-06 Nutritional Research Unit Ltd Huntingdon instruments image analysis apparatus
US4045772A (en) * 1974-04-29 1977-08-30 Geometric Data Corporation Automatic focusing system
US4220850A (en) * 1978-09-29 1980-09-02 Abbott Laboratories Bimodal autofocusing apparatus
US4349254A (en) * 1979-02-13 1982-09-14 Asahi Kogaku Kogyo Kabushiki Kaisha Camera focus detecting device
US4352545A (en) * 1979-02-13 1982-10-05 Asahi Kogaku Kogyo Kabushiki Kaisha Camera focus detecting device
JPS55155308A (en) * 1979-05-23 1980-12-03 Canon Inc Focusing position detecting system
US4283766A (en) * 1979-09-24 1981-08-11 Walt Disney Productions Automatic camera control for creating special effects in motion picture photography
US4414469A (en) * 1980-11-18 1983-11-08 Nippon Kogaku K.K. Automatic focusing apparatus with detection only when the lens is stationary
US4500925A (en) * 1981-06-26 1985-02-19 Hitachi, Ltd. Auto-focusing system for video camera
JPS58153327A (ja) * 1982-03-08 1983-09-12 Toshiba Corp パタ−ン検査装置
US4626674A (en) * 1983-02-10 1986-12-02 Olympus Optical Company, Ltd. Focus detecting method and apparatus
US4544953A (en) * 1983-03-28 1985-10-01 Designs For Vision, Inc. Automatic facusing using slope and peak detection
EP0163394B1 (de) * 1984-04-16 1991-10-09 Image Recognition Systems, Ltd. Automatische Fokussiereinrichtung
US4700298A (en) * 1984-09-14 1987-10-13 Branko Palcic Dynamic microscope image processing scanner
JPH0610694B2 (ja) * 1985-04-12 1994-02-09 株式会社日立製作所 自動焦点合せ方法及び装置
US4673988A (en) * 1985-04-22 1987-06-16 E.I. Du Pont De Nemours And Company Electronic mosaic imaging process
WO1987004530A1 (fr) * 1986-01-20 1987-07-30 Georges Cornuejols Dispositif de traitement d'image pour le controle de la fonction de transfert d'un systeme optique
US4680635A (en) * 1986-04-01 1987-07-14 Intel Corporation Emission microscope
US5084772A (en) * 1986-10-31 1992-01-28 Fuji Photo Film Co., Ltd. Shading correcting method in image reading device
US4887125A (en) * 1987-03-05 1989-12-12 Fuji Photo Film Co., Ltd. Method of and device for detecting focusing condition of image incident upon image sensor
US4851914A (en) * 1987-08-05 1989-07-25 Marco Scientific High-speed full frame imaging CCD camera
US4789898A (en) * 1988-01-19 1988-12-06 Hughes Aircraft Company Demand auto focus driven by scene information only
JPH0834551B2 (ja) * 1988-07-19 1996-03-29 松下電器産業株式会社 自動焦点調整装置
US4948247A (en) * 1988-09-21 1990-08-14 Lapeyre James M High speed stroboscope system for visually observing dynamic properties by moving objects of various characteristics
EP0371422A3 (de) * 1988-11-29 1991-11-27 Konica Corporation Gerät zum Betrieb eines Festkörper-Bildabtasters
US4980778A (en) * 1989-05-11 1990-12-25 At&T Bell Laboratories Method for correcting nonuniformities in pixel output level for a line scanner
US5073857A (en) * 1989-06-01 1991-12-17 Accuron Corporation Method and apparatus for cell analysis
US5089713A (en) * 1989-10-10 1992-02-18 Unisys Corporation Document-imaging illumination arrangements with intensity with adjustment
US5149972A (en) * 1990-01-18 1992-09-22 University Of Massachusetts Medical Center Two excitation wavelength video imaging microscope
JP2841097B2 (ja) * 1990-03-28 1998-12-24 株式会社リコー ストロボ制御装置
US5159642A (en) * 1990-07-13 1992-10-27 Toa Medical Electronics Co., Ltd. Particle image analyzing apparatus
JPH05191715A (ja) * 1990-10-23 1993-07-30 Ricoh Co Ltd ストロボ制御方法
JPH0689687A (ja) * 1990-12-27 1994-03-29 Jeol Ltd 走査電子顕微鏡における自動焦点合わせ装置
US5504584A (en) * 1991-01-30 1996-04-02 Fuji Photo Film Co., Ltd. Video movie camera capable of still photography using a stroboscopic flash
US5204761A (en) * 1991-03-18 1993-04-20 Xerox Corporation Pixel by pixel offset and gain correction in analog data from scanning arrays
US5361140A (en) * 1992-02-18 1994-11-01 Neopath, Inc. Method and apparatus for dynamic correction of microscopic image signals
US5315700A (en) * 1992-02-18 1994-05-24 Neopath, Inc. Method and apparatus for rapidly processing data sequences
US5432552A (en) * 1992-11-04 1995-07-11 Sanyo Electric Co., Ltd. Automatic focusing apparatus including improved digital high-pass filter

Also Published As

Publication number Publication date
AU703583B2 (en) 1999-03-25
WO1996008106A1 (en) 1996-03-14
JPH10505721A (ja) 1998-06-02
EP0809911A1 (de) 1997-12-03
AU3409095A (en) 1996-03-27
ES2123471T1 (es) 1999-01-16
CA2199407C (en) 2002-01-01
EP0809911A4 (de) 1999-10-06
US5912699A (en) 1999-06-15
CA2199407A1 (en) 1996-03-14

Similar Documents

Publication Publication Date Title
DE809911T1 (de) Verfahren und vorrichtung zur schnellen erfassung von fokussierten mikroskopbildern
DE69427860D1 (de) Verfahren und vorrichtung zur projektion von bildern
DE69622518T2 (de) Verfahren und Vorrichtung zur Nachbearbeitung von Bildern
DE69214229T2 (de) Verfahren und Vorrichtung zur Kontrastverbesserung von Bildern
DE69601552T2 (de) Verfahren und vorrichtung zur bildverbesserung
DE69430015T2 (de) Verfahren und vorrichtung zur aufnahme von tonerbildern und flüssiger toner dafür
DE69417704T2 (de) Verfahren und Vorrichtung zur Sichtprüfung von Kontaktlinsen
DE69535692D1 (de) Verfahren und Vorrichtung zur automatisierten Prüfung von Photomasken
DE69724037D1 (de) Verfahren und Vorrichtung zur Erkennung des Inselbetriebs eines Wechselrichters
DE69836540D1 (de) Verfahren und vorrichtung zur ausführung von bildverbesserungen
DE69727993D1 (de) Vorrichtung und Verfahren zur Detektion von Halbbildsynchronsignalen bei HDTV
DE69739006D1 (de) Vorrichtung und verfahren zur aufnahme von standbildern und animationen
DE69637786D1 (de) Verfahren und Vorrichtung zur Anzeige von Halbtonbildern
DE69611977D1 (de) Verfahren und Vorrichtung zur Vermeidung von Fehlerstrom
DE59805342D1 (de) Verfahren und vorrichtung zur bearbeitung von bildobjekten
DE69414913D1 (de) Verfahren und Vorrichtung zur Gewinnung von Bildern der Hornhaut
DE69323863D1 (de) Verfahren und Vorrichtung zur Adressübersetzung
DE69517625T2 (de) Vorrichtung und Verfahren zur Detektion von Bewegungsvektoren
DE69434014D1 (de) Vorrichtung und verfahren zur bilderzeugung
DE69615733T2 (de) Verfahren und Vorrichtung zur Verarbeitung von Bildern
DE69842015D1 (de) Verfahren und Vorrichtung zur Verarbeitung von Videosignalen
DE69614958T2 (de) Gerät und Verfahren zur Detektion von Fingerabdruckmerkmalen
DE59108877D1 (de) Verfahren und Vorrichtung zur Ermittlung von Rasterprozentwerten
DE69514704D1 (de) Verfahren und Vorrichtung zur Detektion von Zwischenzeilen-Abtastung
DE69709558T2 (de) Vorrichtung und Verfahren zur Verbesserung von Teilchenoberflächen