EP0277995A4 - Biomaterial implant with a net positively charged surface. - Google Patents

Biomaterial implant with a net positively charged surface.

Info

Publication number
EP0277995A4
EP0277995A4 EP19870905705 EP87905705A EP0277995A4 EP 0277995 A4 EP0277995 A4 EP 0277995A4 EP 19870905705 EP19870905705 EP 19870905705 EP 87905705 A EP87905705 A EP 87905705A EP 0277995 A4 EP0277995 A4 EP 0277995A4
Authority
EP
European Patent Office
Prior art keywords
positively charged
charged surface
net positively
biomaterial implant
biomaterial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19870905705
Other languages
German (de)
French (fr)
Other versions
EP0277995A1 (en
Inventor
Gershon Golomb
Robert J Levy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Childrens Medical Center Corp
Original Assignee
Childrens Medical Center Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Childrens Medical Center Corp filed Critical Childrens Medical Center Corp
Publication of EP0277995A1 publication Critical patent/EP0277995A1/en
Publication of EP0277995A4 publication Critical patent/EP0277995A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3695—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the function or physical properties of the final product, where no specific conditions are defined to achieve this
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/02—Treatment of implants to prevent calcification or mineralisation in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
EP19870905705 1986-08-20 1987-08-20 Biomaterial implant with a net positively charged surface. Withdrawn EP0277995A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89836186A 1986-08-20 1986-08-20
US898361 1986-08-20

Publications (2)

Publication Number Publication Date
EP0277995A1 EP0277995A1 (en) 1988-08-17
EP0277995A4 true EP0277995A4 (en) 1989-11-07

Family

ID=25409340

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19870905705 Withdrawn EP0277995A4 (en) 1986-08-20 1987-08-20 Biomaterial implant with a net positively charged surface.

Country Status (4)

Country Link
EP (1) EP0277995A4 (en)
JP (1) JPH01500730A (en)
IL (1) IL83592A0 (en)
WO (1) WO1988001155A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0364517B1 (en) * 1988-02-03 1994-04-06 Biomedical Design, Inc. Prevention of prosthesis calcification
US5480963A (en) * 1994-07-22 1996-01-02 United States Surgical Corporation Absorbable copolymers derived from tricarboxylic acids and surgical articles made therefrom
US6193749B1 (en) 1996-02-05 2001-02-27 St. Jude Medical, Inc. Calcification-resistant biomaterials
WO1997027886A1 (en) * 1996-02-05 1997-08-07 St. Jude Medical, Inc. Calcification-resistant biomaterials
US6302909B1 (en) 1996-07-31 2001-10-16 St. Jude Medical, Inc. Calcification-resistant biomaterials
US6254635B1 (en) 1998-02-02 2001-07-03 St. Jude Medical, Inc. Calcification-resistant medical articles
US6391538B1 (en) 2000-02-09 2002-05-21 The Children's Hospital Of Philadelphia Stabilization of implantable bioprosthetic tissue
US7167746B2 (en) 2004-07-12 2007-01-23 Ats Medical, Inc. Anti-coagulation and demineralization system for conductive medical devices
US9844667B2 (en) 2006-04-12 2017-12-19 Medtronic Ats Medical Inc. System for conditioning surfaces in vivo
WO2008121814A1 (en) 2007-03-28 2008-10-09 Ats Medical, Inc. Method for inhibiting platelet interaction with biomaterial surfaces
US8653632B2 (en) 2007-03-28 2014-02-18 Medtronic Ats Medical Inc. System and method for conditioning implantable medical devices
CN111569152A (en) * 2020-05-28 2020-08-25 四川大学 Biological valve with anticoagulation and calcification resistance and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0065827A1 (en) * 1981-04-30 1982-12-01 McNeilab, Inc. Calcification resistant tissue for implantation
EP0103947A2 (en) * 1982-08-25 1984-03-28 McNeilab, Inc. Method for inhibiting mineralization of natural tissue during implantation
EP0174737A2 (en) * 1984-08-14 1986-03-19 Mayo Foundation Treatment of collagenous tissue

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4378224A (en) * 1980-09-19 1983-03-29 Nimni Marcel E Coating for bioprosthetic device and method of making same
US4521564A (en) * 1984-02-10 1985-06-04 Warner-Lambert Company Covalent bonded antithrombogenic polyurethane material

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0065827A1 (en) * 1981-04-30 1982-12-01 McNeilab, Inc. Calcification resistant tissue for implantation
EP0103947A2 (en) * 1982-08-25 1984-03-28 McNeilab, Inc. Method for inhibiting mineralization of natural tissue during implantation
EP0174737A2 (en) * 1984-08-14 1986-03-19 Mayo Foundation Treatment of collagenous tissue

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO8801155A1 *

Also Published As

Publication number Publication date
WO1988001155A1 (en) 1988-02-25
JPH01500730A (en) 1989-03-16
EP0277995A1 (en) 1988-08-17
IL83592A0 (en) 1988-01-31

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

17P Request for examination filed

Effective date: 19880825

RHK1 Main classification (correction)

Ipc: A61L 27/00

A4 Supplementary search report drawn up and despatched

Effective date: 19891107

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN

18W Application withdrawn

Withdrawal date: 19910222

R18W Application withdrawn (corrected)

Effective date: 19910222