EP0352907A3 - Low calorie fat substitute compositions resistant to laxative side effect - Google Patents

Low calorie fat substitute compositions resistant to laxative side effect Download PDF

Info

Publication number
EP0352907A3
EP0352907A3 EP19890306407 EP89306407A EP0352907A3 EP 0352907 A3 EP0352907 A3 EP 0352907A3 EP 19890306407 EP19890306407 EP 19890306407 EP 89306407 A EP89306407 A EP 89306407A EP 0352907 A3 EP0352907 A3 EP 0352907A3
Authority
EP
European Patent Office
Prior art keywords
low calorie
calorie fat
side effect
fat substitute
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP19890306407
Other languages
German (de)
French (fr)
Other versions
EP0352907A2 (en
EP0352907B1 (en
Inventor
Norman Bratton Howard
David Charles Kleinschmidt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Publication of EP0352907A2 publication Critical patent/EP0352907A2/en
Publication of EP0352907A3 publication Critical patent/EP0352907A3/en
Application granted granted Critical
Publication of EP0352907B1 publication Critical patent/EP0352907B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/346Finished or semi-finished products in the form of powders, paste or liquids
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00Other edible oils or fats, e.g. shortenings, cooking oils
    • A23D9/007Other edible oils or fats, e.g. shortenings, cooking oils characterised by ingredients other than fatty acid triglycerides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21Addition of substantially indigestible substances, e.g. dietary fibres
    • A23L33/25Synthetic polymers, e.g. vinylic or acrylic polymers
    • A23L33/26Polyol polyesters, e.g. sucrose polyesters; Synthetic sugar polymers, e.g. polydextrose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G2200/00COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents
    • A23G2200/06COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents containing beet sugar or cane sugar if specifically mentioned or containing other carbohydrates, e.g. starches, gums, alcohol sugar, polysaccharides, dextrin or containing high or low amount of carbohydrate
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G2200/00COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents
    • A23G2200/08COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents containing cocoa fat if specifically mentioned or containing products of cocoa fat or containing other fats, e.g. fatty acid, fatty alcohol, their esters, lecithin, paraffins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Child & Adolescent Psychology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Jellies, Jams, And Syrups (AREA)

Abstract

The present invention relates to low calorie fat substitute compositions that are useful as fat replacements in low calorie foods, and as pharmaceutical compositions. Sucrose fatty acid esters are preferred low calorie fat substitutes. The compositions are highly resistant to an undesirable laxative side effect. These benefits are achieved by formulating compositions comprising a liquid polyol fatty acid polyester, at least about 10% solid low calorie fat substitute by weight of the liquid polyester, and at least about 1% of a cohesive network of polysaccharide fibrils and microfibrils, for example microfibrillated cellulose, by weight of the liquid polyester.
EP89306407A 1988-06-27 1989-06-23 Low calorie fat substitute compositions resistant to laxative side effect Expired - Lifetime EP0352907B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21180288A 1988-06-27 1988-06-27
US211802 1988-06-27

Publications (3)

Publication Number Publication Date
EP0352907A2 EP0352907A2 (en) 1990-01-31
EP0352907A3 true EP0352907A3 (en) 1991-08-07
EP0352907B1 EP0352907B1 (en) 1994-04-20

Family

ID=22788421

Family Applications (1)

Application Number Title Priority Date Filing Date
EP89306407A Expired - Lifetime EP0352907B1 (en) 1988-06-27 1989-06-23 Low calorie fat substitute compositions resistant to laxative side effect

Country Status (12)

Country Link
US (1) US5006360B1 (en)
EP (1) EP0352907B1 (en)
JP (1) JP2804091B2 (en)
AU (1) AU626552B2 (en)
CA (1) CA1326162C (en)
DE (1) DE68914742T2 (en)
DK (1) DK319589A (en)
HK (1) HK117196A (en)
IE (1) IE62783B1 (en)
MY (1) MY106082A (en)
NZ (1) NZ229720A (en)
PH (1) PH26707A (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8829833D0 (en) * 1988-12-21 1989-02-15 Unilever Plc Low-calorie food products
EP0434164A3 (en) * 1989-12-21 1993-01-13 Unilever N.V. Frying-fat composition
ATE147587T1 (en) * 1990-07-20 1997-02-15 Unilever Nv EDIBLE COMPOSITION CONTAINING FAT
WO1992007475A1 (en) * 1990-10-31 1992-05-14 The Procter & Gamble Company Calcium fortified sauces
US5230913A (en) * 1991-03-01 1993-07-27 Nabisco, Inc. Fat mimetic having mineral core with fatty coating
US5366753A (en) * 1991-03-29 1994-11-22 Curtice-Burns, Inc. Fat substitute compositions having reduced laxative effects at low levels of inclusion
US5294451A (en) * 1991-03-29 1994-03-15 Curtice-Burns, Inc. Fat substitute compositions having reduced laxative effects
ES2146350T3 (en) 1991-06-25 2000-08-01 Danisco Finland Oy LOW CALORIE FAT SUBSTITUTE.
DE69212836T2 (en) * 1991-09-03 1997-02-20 Procter & Gamble USE OF HYDROPHOBIC SILICA TO LIMIT OR PREVENT PASSIVE OIL LOSS
JPH0568478A (en) * 1991-09-17 1993-03-23 Daicel Chem Ind Ltd Agent for improving water retention of fat and oil composition
US5492715A (en) * 1994-03-31 1996-02-20 Greenland; Frederick A. Dual function fruit concentrate sweetener and fat substitute and method of making
DE19628324A1 (en) * 1996-07-13 1998-01-15 Hocepro Gmbh I G Cellulose fibrils
JP2003512343A (en) 1999-10-15 2003-04-02 ダニスコ カルター アメリカ,インコーポレイテッド Method for direct esterification of sorbitol with fatty acids
US6361817B1 (en) 1999-12-17 2002-03-26 Bestfoods Low calorie nut butters
KR101040446B1 (en) * 2002-04-19 2011-06-09 맷슨 테크놀로지, 인크. System for depositing a film onto a substrate using a low vapor pressure gas precursor
ATE541562T1 (en) * 2002-06-17 2012-02-15 Taro Pharmaceuticals Usa Inc IBUPROFEN SUSPENSION
US20040097427A1 (en) * 2002-08-13 2004-05-20 The Iams Company Method for controlling hairballs
WO2005076829A2 (en) * 2004-02-05 2005-08-25 Taro Pharmaceuticals U.S.A., Inc. Stable loratadine spill resistant formulation
KR20090004838A (en) * 2005-08-01 2009-01-12 씨피 켈코 유에스, 인코포레이티드 Low-sediment acidic protein beverages
CA2839353C (en) * 2011-06-23 2016-01-26 The Procter & Gamble Company Sucrose polyesters

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4005195A (en) * 1976-02-12 1977-01-25 The Procter & Gamble Company Compositions for treating hypercholesterolemia
US4005196A (en) * 1976-02-12 1977-01-25 The Procter & Gamble Company Vitaminized compositions for treating hypercholesterolemia
US4341807A (en) * 1980-10-31 1982-07-27 International Telephone And Telegraph Corporation Food products containing microfibrillated cellulose
US4374702A (en) * 1979-12-26 1983-02-22 International Telephone And Telegraph Corporation Microfibrillated cellulose
US4774095A (en) * 1986-12-16 1988-09-27 The Procter & Gamble Company Filling-containing, dough-based products containing cellulosic fibrils and microfibrils
EP0290216A2 (en) * 1987-05-06 1988-11-09 The Procter & Gamble Company Polyol fatty acid polyesters for treating duodenal ulcers

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE207070C (en) *
US2831854A (en) * 1955-05-24 1958-04-22 Procter & Gamble Method for preparing fatty esters of non-reducing oligosaccharides in the presence of an amide
US2874175A (en) * 1955-10-04 1959-02-17 Reuben O Feuge Process for making fatty acid diglyceride, diesters of dibasic acids
US2962419A (en) * 1957-05-20 1960-11-29 Heyden Newport Chemical Corp Dietetic compositions
US3600186A (en) * 1968-04-23 1971-08-17 Procter & Gamble Low calorie fat-containing food compositions
US3579548A (en) * 1968-05-10 1971-05-18 Procter & Gamble Triglyceride esters of alpha-branched carboxylic acids
US3932532A (en) * 1973-06-01 1976-01-13 Ici United States Inc. Ethers of polyglycerol
US3954976A (en) * 1973-12-14 1976-05-04 The Procter & Gamble Company Pharmaceutical compositions for inhibiting absorption of cholesterol
US3963699A (en) * 1974-01-10 1976-06-15 The Procter & Gamble Company Synthesis of higher polyol fatty acid polyesters
IE44458B1 (en) * 1976-02-12 1981-12-02 Procter & Gamble Compositions for treating hypercholesterolemia
US4304768A (en) * 1980-03-31 1981-12-08 General Foods Corporation Low-calorie foods
US4378381A (en) * 1980-10-31 1983-03-29 International Telephone And Telegraph Corporation Suspensions containing microfibrillated cellulose
US4461782A (en) * 1982-02-16 1984-07-24 The Procter & Gamble Company Low calorie baked products
US4481076A (en) * 1983-03-28 1984-11-06 International Telephone And Telegraph Corporation Redispersible microfibrillated cellulose
US4508746A (en) * 1983-06-20 1985-04-02 Cpc International Inc. Low calorie edible oil substitutes
US4518772A (en) * 1983-06-23 1985-05-21 The Proctor & Gamble Company Synthesis of higher polyol fatty acid polyesters using high soap:polyol ratios
US4517360A (en) * 1983-06-23 1985-05-14 The Procter & Gamble Company Synthesis of higher polyol fatty acid polyesters using carbonate catalysts
US4582927A (en) * 1984-04-04 1986-04-15 Frito-Lay, Inc. Synthetic cooking oils containing dicarboxylic acid esters
JPS61113601A (en) * 1984-11-07 1986-05-31 Ajinomoto Co Inc Cellulosic macerated material and production thereof
US4582715A (en) * 1984-12-04 1986-04-15 The Procter & Gamble Company Acylated glycerides useful in low calorie fat-containing food compositions
CA1300425C (en) * 1985-06-10 1992-05-12 Cecil L. Frye Fat and oil replacements as human food ingredients
EP0236288B1 (en) * 1986-02-20 1993-12-15 The Procter & Gamble Company Low calorie fat materials that eliminate laxative side effect
DE3788661T2 (en) * 1986-02-20 1994-05-19 Procter & Gamble Low calorie fat products with improved taste.
US4861613A (en) * 1986-07-25 1989-08-29 Arco Chemical Technology, Inc. Non-digestible fat substitutes of low-caloric value
US4925692A (en) * 1988-11-07 1990-05-15 Dow Corning Corporation Food composition containing a siloxane polymer and a particulate silica

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4005195A (en) * 1976-02-12 1977-01-25 The Procter & Gamble Company Compositions for treating hypercholesterolemia
US4005196A (en) * 1976-02-12 1977-01-25 The Procter & Gamble Company Vitaminized compositions for treating hypercholesterolemia
US4374702A (en) * 1979-12-26 1983-02-22 International Telephone And Telegraph Corporation Microfibrillated cellulose
US4341807A (en) * 1980-10-31 1982-07-27 International Telephone And Telegraph Corporation Food products containing microfibrillated cellulose
US4774095A (en) * 1986-12-16 1988-09-27 The Procter & Gamble Company Filling-containing, dough-based products containing cellulosic fibrils and microfibrils
EP0290216A2 (en) * 1987-05-06 1988-11-09 The Procter & Gamble Company Polyol fatty acid polyesters for treating duodenal ulcers

Also Published As

Publication number Publication date
EP0352907A2 (en) 1990-01-31
DK319589D0 (en) 1989-06-27
US5006360A (en) 1991-04-09
AU3707289A (en) 1990-01-04
IE892070L (en) 1989-12-27
DK319589A (en) 1989-12-28
NZ229720A (en) 1992-01-29
EP0352907B1 (en) 1994-04-20
MY106082A (en) 1995-03-31
PH26707A (en) 1992-09-15
HK117196A (en) 1996-07-12
CA1326162C (en) 1994-01-18
JP2804091B2 (en) 1998-09-24
DE68914742T2 (en) 1994-09-29
US5006360B1 (en) 1992-04-28
IE62783B1 (en) 1995-02-22
JPH02109956A (en) 1990-04-23
AU626552B2 (en) 1992-08-06
DE68914742D1 (en) 1994-05-26

Similar Documents

Publication Publication Date Title
EP0352907A3 (en) Low calorie fat substitute compositions resistant to laxative side effect
AU672733B2 (en) Whipping cream compositions
EP0375238A3 (en) Shelf stable, highly aerated reduced calorie food products
CA2096044A1 (en) Reduced calorie cocoa butter substitutes
GB8716111D0 (en) Edible plastic dispersion
CA2076647A1 (en) Branched fructo-oligosaccharides, a method for obtaining them and uses of products containing them
AU648754B2 (en) Proanthocyanidol-based composition and its pharmacological application
ES2131123T3 (en) STARCH ESTER BLENDS WITH LINEAR POLYESTERS.
EP0571219A3 (en) Esterified propoxylated glycerin fat substitute compositions resistant to gastrointestinal side effects
ES2035764A1 (en) Low calorie meat products and a process for preparing same.
IE790595L (en) Edible coating oil
CA2309031A1 (en) Surface-modified cellulose as low calorie flour replacements
CA2031879A1 (en) Compositions useful as high temperature media
WO1991015957A3 (en) A dough or batter composition, a process for making a fat-reduced bakery product, and a fat-reduced bakery product
AU6307896A (en) Meltprocessible starch composition, a process for the preparation thereof and the use of the composition
EP0382578A3 (en) Substitution of degraded cellulose derivatives for high calorie ingredients in foods
EP0325463A3 (en) Low calorie fat mimetics
AU7263791A (en) Lipid-free polysaccharide compound, preparation process, compositions containing it
CA2241048A1 (en) Fatty acid esterified propoxylated glycerin as frying oil compositions
EP1033079A3 (en) Freezable low-calorie spoonable dressings and method for their production
EP0377237A3 (en) Low-calorie confectionery products
CA2240403A1 (en) Reduced calorie cheese products
EP0383380A3 (en) Edible fat-containing products
AU653357B2 (en) Composition consisting of broken edible seed kernels or broken edible beans and one or more edible fats
CA2037788A1 (en) Quality-improving agents for fish meat surimi

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE CH DE ES FR GB GR IT LI LU NL SE

PUAL Search report despatched

Free format text: ORIGINAL CODE: 0009013

AK Designated contracting states

Kind code of ref document: A3

Designated state(s): AT BE CH DE ES FR GB GR IT LI LU NL SE

17P Request for examination filed

Effective date: 19920107

17Q First examination report despatched

Effective date: 19921005

RBV Designated contracting states (corrected)

Designated state(s): BE CH DE FR GB LI NL

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): BE CH DE FR GB LI NL

REF Corresponds to:

Ref document number: 68914742

Country of ref document: DE

Date of ref document: 19940526

ET Fr: translation filed
PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed
PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: NL

Payment date: 19990322

Year of fee payment: 11

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: BE

Payment date: 19990715

Year of fee payment: 11

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: CH

Payment date: 19990726

Year of fee payment: 11

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20000630

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20000630

Ref country code: BE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20000630

BERE Be: lapsed

Owner name: THE PROCTER & GAMBLE CY

Effective date: 20000630

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20010101

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

NLV4 Nl: lapsed or anulled due to non-payment of the annual fee

Effective date: 20010101

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20010531

Year of fee payment: 13

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 20010627

Year of fee payment: 13

REG Reference to a national code

Ref country code: GB

Ref legal event code: IF02

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20020501

Year of fee payment: 14

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20030101

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: FR

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20030228

REG Reference to a national code

Ref country code: FR

Ref legal event code: ST

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20030623

GBPC Gb: european patent ceased through non-payment of renewal fee

Effective date: 20030623