EP0561322A1 - Dropper bottle for two products to be mixed prior to use - Google Patents

Dropper bottle for two products to be mixed prior to use Download PDF

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Publication number
EP0561322A1
EP0561322A1 EP93104161A EP93104161A EP0561322A1 EP 0561322 A1 EP0561322 A1 EP 0561322A1 EP 93104161 A EP93104161 A EP 93104161A EP 93104161 A EP93104161 A EP 93104161A EP 0561322 A1 EP0561322 A1 EP 0561322A1
Authority
EP
European Patent Office
Prior art keywords
reservoir
cap
neck
ring
union
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP93104161A
Other languages
German (de)
French (fr)
Other versions
EP0561322B1 (en
Inventor
Evro Fabbri
Giovanni Ferrari
Antonio Fontana
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lameplast SRL
Original Assignee
Lameplast SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lameplast SRL filed Critical Lameplast SRL
Publication of EP0561322A1 publication Critical patent/EP0561322A1/en
Application granted granted Critical
Publication of EP0561322B1 publication Critical patent/EP0561322B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00Closures not otherwise provided for
    • B65D51/24Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes
    • B65D51/28Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials
    • B65D51/2807Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container
    • B65D51/2814Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container the additional article or materials being released by piercing, cutting or tearing an element enclosing it
    • B65D51/2842Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container the additional article or materials being released by piercing, cutting or tearing an element enclosing it said element being provided with a preformed weakened line
    • B65D51/285Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container the additional article or materials being released by piercing, cutting or tearing an element enclosing it said element being provided with a preformed weakened line ruptured by a sharp element, e.g. a cutter or a piercer

Definitions

  • the invention concerns a dropping bottle particularly for pharmaceutical products which, prior to use, are activated by being mixed together, namely, a deformable plastic container, generally containing a liquid substance, into which another, generally powdery, substance contained in a reservoir above is precipitated, following the partial thrust-shearing of the diaphragm forming the bottom of said reservoir by the lower cutting end of the dropper sliding inside the reservoir itself: the top end of said dropper being covered by a cap which also serves to apply down-thrust to the dropper; the liquid substance and the powdery one, or also two liquid substances, being of a medicinal or cosmetic nature.
  • the prior art comprises flexible bottles with a cylindrical reservoir open at the top, its lower extremity being anchored internally and externally to the neck of the bottle and its base consisting of a diaphragm shearing peripherally on thrust being applied to a rigid dropper having a chisel-shaped lower cutting-end and a top dispensing-end featuring a calibrated aperture and fitted with a cap that closes, protects and actuates and which forms a close, sliding fit on the outer cylindrical surface of said reservoir when actuated by pressure being applied to the top of said cap in order to shear said diaphragm and so cause the two substances to mix.
  • the invention resolves said technical problem by adopting a bottle surmounted by a reservoir having a base in the form of a diaphragm shearing as a result of down-thrust applied to the cap enclosing the top of the dropper, said dropper having a chisel-shaped lower cutting end, the casing of said cap extending towards the neck of the bottle in at least one continuous or sectional warranty seal, delimited by shear lines, as required, said casing having, at its lower extremity, a lip protruding inwards and lodging in a corresponding groove cut into the reservoir or into an external downwards extension of the same: the whole of the casing and the warranty seal being substantially continuous at least as far as the step at the top of the union square to the neck of the bottle; the presence of said seal preventing both the activation of mixing, in the case of down-thrust being applied to the cap, and the removal of said cap, given the impossibility of the cap's sliding axially when the warranty seal has not been torn off.
  • the advantages of the invention are: the impossibility of perforating the diaphragm without removing the warranty seal; the impossibility of sliding the cap off without removing the warranty seal and hence the impossibility of gaining access to the substance contained in the reservoir without leaving evidence of tampering, namely, the absence of the warranty seal and the presence of any separable lower remains of it.
  • Figure 1 is the enlarged axial section of the top part of the bottle, fitted with a mixing device with tamper-proof seal, in the embodiment wherein the lower end of the cap comprises a warranty seal with below it a separable annular element and with a union to the neck integral with the reservoir: the whole as it appears before use;
  • Figure 2 is a section as in Figure 1, but in the mixing phase prior to use;
  • Figure 3 is a part-sectional view of the whole of the element that actuates, protects and offers warranty and also serves as a plug;
  • Figure 4 is the cross-section IV-IV of Figure 3;
  • Figure 5 is a partial section of the rigid body of the dropper for dispensing measured drops having a funnel at the top and a perforator at the bottom;
  • Figure 6 is a partial section of the reservoir containing the substance to be fed into the body of the bottle below and mounted on the neck of said bottle;
  • Figure 7 is a partial section of the body, incomplete
  • the figures show: the body of the bottle 1, having a neck 2, for example with a lower locating ring 3 acting as an assembly bearing; one or more annular projections or threads 4 connecting with a union 5 having a watertight inner lip 6 of the hollow cylindrical body 7 of the dispenser of the substance, be it liquid, powder or solid, to be mixed with the liquid in the bottle below; a diaphragm 8 with a predetermined peripheral shear-line, supporting the substance contained in the chamber 9 of the reservoir 7; a hollow, cylindrical intermediate body 10 of the dropper, a bottom end being chisel-shaped so as to shear the diaphragm 8; an upper funnel 12 of the body 10, acting as a dropper; a ring 13 forming the outside edge of the funnel 12 to arrest the downstroke of the dropper once shearing is complete; an upper outer ring 14 and a lower ring 15 respectively of the hollow cylindrical body 10 of the dropper forming a watertight seal; a multi-function hollow cylindrical element 16, in the form of a cap
  • the separable lower annular section below the warranty seal is anchored to the body 7 of the reservoir ( Figures 1, 9); in the embodiment of Figure 8, the separable annular section of the warranty seal is anchored to the neck of the bottle 1; in the embodiment of Figure 10, said separable annular section is anchored under the bottom lip of the union 5 of the body 7 of the reservoir to the neck 2; in the embodiment of Figure 11, with said lower annular section missing, the warranty seal 33 is anchored to the body 7 of the reservoir.

Abstract

A bottle (1) designed to contain two substances to be mixed immediately prior to use so as to obtain a medicine or cosmetic, the first contained in a reservoir (7) having a diaphragm bottom (8) that shears as a result of down-thrust applied to the top of a cap (16) consisting of a tear-off warranty seal (20) advantageously interposed, for tearing off, between the lower extremity of the cap itself and a lower annular element (26) anchored to the lower part of said reservoir; it being envisaged that the mixing of the two substances and the removal of the cap cannot take place without the warranty seal being torn off. For use in the fields of pharmaceuticals and cosmetics.

Description

  • The invention concerns a dropping bottle particularly for pharmaceutical products which, prior to use, are activated by being mixed together, namely, a deformable plastic container, generally containing a liquid substance, into which another, generally powdery, substance contained in a reservoir above is precipitated, following the partial thrust-shearing of the diaphragm forming the bottom of said reservoir by the lower cutting end of the dropper sliding inside the reservoir itself: the top end of said dropper being covered by a cap which also serves to apply down-thrust to the dropper; the liquid substance and the powdery one, or also two liquid substances, being of a medicinal or cosmetic nature.
  • The prior art comprises flexible bottles with a cylindrical reservoir open at the top, its lower extremity being anchored internally and externally to the neck of the bottle and its base consisting of a diaphragm shearing peripherally on thrust being applied to a rigid dropper having a chisel-shaped lower cutting-end and a top dispensing-end featuring a calibrated aperture and fitted with a cap that closes, protects and actuates and which forms a close, sliding fit on the outer cylindrical surface of said reservoir when actuated by pressure being applied to the top of said cap in order to shear said diaphragm and so cause the two substances to mix.
  • However, such a cap does not make apparent any modifications that may have been made to the substances contained in the reservoir, in that said reservoir is accessible from above, for example, with a syringe, merely by removing the cap which adheres to the outside of the reservoir itself by friction alone or is anchored in a slight undercut that can easily be overcome by a backwards pulling action exerted by the fingers. Said prior art is susceptible of considerable improvement with a view to eliminating this drawback.
  • From the foregoing emerges the need to resolve the technical problem of inventing a safety-bottle that does not allow the two substances to be mixed, following the shearing of the diaphragm by the dropper on pressure being applied to the cap, without prior elimination of a warranty element, removal of which will constitute evidence of tampering.
  • The invention resolves said technical problem by adopting a bottle surmounted by a reservoir having a base in the form of a diaphragm shearing as a result of down-thrust applied to the cap enclosing the top of the dropper, said dropper having a chisel-shaped lower cutting end, the casing of said cap extending towards the neck of the bottle in at least one continuous or sectional warranty seal, delimited by shear lines, as required, said casing having, at its lower extremity, a lip protruding inwards and lodging in a corresponding groove cut into the reservoir or into an external downwards extension of the same: the whole of the casing and the warranty seal being substantially continuous at least as far as the step at the top of the union square to the neck of the bottle; the presence of said seal preventing both the activation of mixing, in the case of down-thrust being applied to the cap, and the removal of said cap, given the impossibility of the cap's sliding axially when the warranty seal has not been torn off.
  • The advantages of the invention are: the impossibility of perforating the diaphragm without removing the warranty seal; the impossibility of sliding the cap off without removing the warranty seal and hence the impossibility of gaining access to the substance contained in the reservoir without leaving evidence of tampering, namely, the absence of the warranty seal and the presence of any separable lower remains of it.
  • Some embodiments of the invention are illustrated, by way of example, in the four tables of drawing attached, in which: Figure 1 is the enlarged axial section of the top part of the bottle, fitted with a mixing device with tamper-proof seal, in the embodiment wherein the lower end of the cap comprises a warranty seal with below it a separable annular element and with a union to the neck integral with the reservoir: the whole as it appears before use; Figure 2 is a section as in Figure 1, but in the mixing phase prior to use; Figure 3 is a part-sectional view of the whole of the element that actuates, protects and offers warranty and also serves as a plug; Figure 4 is the cross-section IV-IV of Figure 3; Figure 5 is a partial section of the rigid body of the dropper for dispensing measured drops having a funnel at the top and a perforator at the bottom; Figure 6 is a partial section of the reservoir containing the substance to be fed into the body of the bottle below and mounted on the neck of said bottle; Figure 7 is a partial section of the body, incomplete, of the bottle generally containing liquid; Figure 8 is a section as in Figure 1, but restricted to the upper middle part, in an embodiment of the bottle that has the lower annular section of the multi-function hollow cylindrical element integral with the union to the neck of the bottle; Figure 9 is an analogous section of another embodiment, in which said union is independent both of said hollow cylindrical element and of the body of the reservoir; Figure 10 is an analogous section of another embodiment, wherein the lower part of the cap has a warranty seal of which the lower separable ring extends and broadens into a sort of cap enclosing the union, integral with the reservoir, mounted on the neck; Figure 11 is an analogous section of another embodiment, simplified with respect to that of Figure 1, wherein the warranty seal is without a separable lower annular section.
  • It is to be noted that the embodiment of Figure 11 can be combined with that of Figure 9, wherein the neck union is independent of the reservoir.
  • The figures show: the body of the bottle 1, having a neck 2, for example with a lower locating ring 3 acting as an assembly bearing; one or more annular projections or threads 4 connecting with a union 5 having a watertight inner lip 6 of the hollow cylindrical body 7 of the dispenser of the substance, be it liquid, powder or solid, to be mixed with the liquid in the bottle below; a diaphragm 8 with a predetermined peripheral shear-line, supporting the substance contained in the chamber 9 of the reservoir 7; a hollow, cylindrical intermediate body 10 of the dropper, a bottom end being chisel-shaped so as to shear the diaphragm 8; an upper funnel 12 of the body 10, acting as a dropper; a ring 13 forming the outside edge of the funnel 12 to arrest the downstroke of the dropper once shearing is complete; an upper outer ring 14 and a lower ring 15 respectively of the hollow cylindrical body 10 of the dropper forming a watertight seal; a multi-function hollow cylindrical element 16, in the form of a cap, with a top end 17 incorporating a stopper 18 for the dropper funnel 12 and a watertight bushing 19; a warranty-seal 20 being an extension downwards of said cap 16 and separable from it by tearing along the circumferences 21, 22, designed to shear after removal of the tabs 23 straddling the vertical line between the edges of said seal; two sectorial annular portions 24 of the hollow cylindrical body 7 of the reservoir, acting as an air-vent where necessary, as in the case of freeze-drying; a lower outer ring 25 of the hollow cylindrical body 7 of the reservoir to anchor, on assembly, a separable lower annular section 26 of the cap 16 to the body 7 of said reservoir by means of a lower inner ring 27 of the lower annular section 2b destined, initially, to prevent the cap 16, or multi-function element 16, 20, 26, from sliding off, being anchored under said outer ring 25; an outer base-ring 28 of the element 26 to suspend it during advancement on assembly; a lower annular section 29 (Figure 8) of the multi-function hollow cylindrical element 16, integral with the union to the neck 2 of the bottle 1; a hollow cylindrical body 30 of the reservoir without the union 5; a flat lower ring 30a of the reservoir 30 lodging in a step in the rim of the neck 2; a sleeve coupling 31 (Figure 9) securing the hollow cylindrical body 7 of the reservoir to the neck 2 of the bottle 1 rendered independent of said body; a lower section 32 (Figure 10) of the hollow cylindrical element 16, below the warranty seal 20, in the shape of a separable ring extending downwards to form a cap; a lower inner ring 32a of the cap 32 anchored in undercut under the union 5 of the reservoir; a lower part 33 (Figure 11) of the hollow cylindrical device 16, acting as a warranty-seal and anchoring ring.
  • It is to be noted that, in two of the embodiments, the separable lower annular section below the warranty seal is anchored to the body 7 of the reservoir (Figures 1, 9); in the embodiment of Figure 8, the separable annular section of the warranty seal is anchored to the neck of the bottle 1; in the embodiment of Figure 10, said separable annular section is anchored under the bottom lip of the union 5 of the body 7 of the reservoir to the neck 2; in the embodiment of Figure 11, with said lower annular section missing, the warranty seal 33 is anchored to the body 7 of the reservoir.
  • In practice, the materials, dimensions, the shape of the bottle and the details of execution can differ from those indicated, while being technically equivalent, without thereby departing from the juridical domain of the present invention.

Claims (6)

  1. A dropping bottle particularly for pharmaceutical products to be activated by mixing prior to use, comprising a deformable bottle body (1) having a neck (2) onto which is mounted a union (5) with a reservoir (7), containing the substance to be mixed supported on a diaphragm (8) which can be partly thrust-sheared by means of a rigid dropper (10) having a chisel-shaped bottom end (11), the top end of said dropper marrying with a cap (16) which seals, protects and actuates, characterized in that, the internal surface of said cap sliding vertically on the outer surface of said reservoir, at least an annular element is interposed between the bottom end of said cap and the rim of the neck (2) to form a tear-off warranty seal detaching from said cap along a circumference (21), designed to shear as required: said annular element being anchored at the bottom, so preventing any push-pull axial movement of said cap.
  2. A dropping bottle, as claimed in Claim 1, characterized in that said warranty seal consists of a tear-off ring (20) delimited top and bottom by two circumferences (21, 22) designed to shear as required the lower circumference (22) separating said warranty seal from a lower ring (26), having an internal ring (27) lodging securely under a lower ring (25) forming a rib on the outer surface of the reservoir (7) in turn anchorored to the neck (2) of the bottle (1).
  3. A dropping bottle, as claimed in Claim 2, characterized in that, the cap (16) having a lower tear-off warranty seal (20) surmounting a separable annular element anchored to the reservoir (7), said reservoir has a lower ring (30a) for insertion into the rim of the neck (2); it being envisaged that said annular element (29), being separable from the warranty seal (20) above it, is integral with the union (30b) below it anchored to the neck itself: the latter having a plane surface with a step to keep said lower ring inserted in said rim.
  4. A dropping bottle, as claimed in Claim 3, characterized in that, the cap (16) having a lower tear-off warranty seal (20) surmounting a separable annular element (26), anchored at the base to the reservoir (7), said reservoir is kept in firm contact with the neck (2) by compression of the lower ring (30a) in the relative inner groove of said neck by means of the flat square-cut upper lip of the union (31) rendered independent of said reservoir and anchored to the outside of said neck.
  5. A dropping bottle, as claimed in claim 2, characterized in that, the cap (16) having a tear-off warranty seal (20) surmounting a separable lower ring, said ring is integral with the union (32) below it encasing the union (5) of the reservoir (7): it being envisaged that the lower inner lip (32a) of the union (5) of said separable ring be anchored in undercut under said union of the reservoir.
  6. A dropping bottle, as claimed in claim 1, characterized in that, the bottom end of the cap (16) having a separable rim (33) with a lower inner annular projection (27) lodging under the lower outer annular projection (25) of the reservoir (7), said ring constitutes a warranty seal.
EP93104161A 1992-03-19 1993-03-15 Dropper bottle for two products to be mixed prior to use Expired - Lifetime EP0561322B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMO920035 1992-03-19
ITMO920035A IT1259924B (en) 1992-03-19 1992-03-19 DROPPER BOTTLE PARTICULARLY FOR PHARMACEUTICAL PRODUCTS ACTIVATED FOR MIXING USE

Publications (2)

Publication Number Publication Date
EP0561322A1 true EP0561322A1 (en) 1993-09-22
EP0561322B1 EP0561322B1 (en) 1996-10-23

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Family Applications (1)

Application Number Title Priority Date Filing Date
EP93104161A Expired - Lifetime EP0561322B1 (en) 1992-03-19 1993-03-15 Dropper bottle for two products to be mixed prior to use

Country Status (4)

Country Link
EP (1) EP0561322B1 (en)
DE (1) DE69305553T2 (en)
ES (1) ES2096788T3 (en)
IT (1) IT1259924B (en)

Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0577200A1 (en) * 1992-07-02 1994-01-05 Laboratorios Cusi, S.A. Pharmaceutical product container for two separate substances, having a device for mixing and dosed dispensation
ES2064277A1 (en) * 1993-03-30 1995-01-16 Cusi Lab Pharmaceutical-product container with two separated substances and device for mixing and metered dispensing
EP0778221A1 (en) * 1995-12-04 1997-06-11 Laboratorios Cusi, S.A. Pharmaceutical container with two seperate substances, with a mixing device, dosed application and assembly process thereof
EP0921079A1 (en) * 1997-12-02 1999-06-09 Plastikwerk Expan GesmbH Two compartment container
WO1999039987A1 (en) 1998-02-09 1999-08-12 Tengiz Kekelidze Stopper
WO2001005675A1 (en) 1999-07-19 2001-01-25 Societe Des Produits Nestle S.A. An assembly for two products to be mixed just prior to use
EP1087894A1 (en) * 1998-03-20 2001-04-04 Seaquist Closures Foreign, Inc Dispensing structure with frangible membrane for separating two products
GB2365405A (en) * 2000-08-01 2002-02-20 Lily Hsu A container and closure assembly with multiple storage compartments
AT410085B (en) * 1997-12-02 2003-01-27 Feichtinger Ernst Expan Container for separated fluids
WO2004031048A1 (en) * 2002-10-04 2004-04-15 Sheldon Denholm Tree Liquid dispensing device
WO2005044430A3 (en) * 2003-11-10 2005-08-04 Jeong-Min Lee Method and structure for mixing different materials in the pouch container
WO2005087606A1 (en) * 2004-03-09 2005-09-22 Wendon Limited Volumetric dispenser
EP1687217A1 (en) * 2003-11-05 2006-08-09 Jeong-Min Lee Method and structure for mixing different materials
US7114403B2 (en) 2003-05-30 2006-10-03 Oakville Hong Kong Co., Ltd Fluid collection and application device and methods of use of same
US7210575B2 (en) 2002-09-26 2007-05-01 Boehringer Ingelheim International Gmbh Two-component packaging unit
US7544324B2 (en) 2003-11-14 2009-06-09 Oakville Hong Kong Company Limited Rapid sample analysis storage devices and methods of use
DE102008000802A1 (en) 2008-03-20 2009-10-08 Faurecia Innenraum Systeme Gmbh Fully automatic storage compartment
WO2010019096A1 (en) * 2008-08-11 2010-02-18 Astrazeneca Ab A pre-filled container insert for mixing two or more ingredients for use in a pharmaceutical container system
WO2011060456A1 (en) * 2009-11-10 2011-05-19 Ewan Dirk Kromhout An accessory for a container
US8071394B2 (en) 2006-07-26 2011-12-06 Alere Switzerland Gmbh Test device for detecting an analyte in a liquid sample
ITMO20100326A1 (en) * 2010-11-12 2012-05-13 Punto Pack S R L CAPSULE PERFECTED FOR SUBSTANCES TO BE MIXED AT THE TIME OF USE.
US8871155B2 (en) 2005-11-30 2014-10-28 Alere Switzerland Gmbh Devices for detecting analytes in fluid sample
ITUB20159655A1 (en) * 2015-12-23 2017-06-23 Bormioli Rocco Spa Safety capsule of a container.
IT201600080494A1 (en) * 2016-08-01 2018-02-01 Lameplast Spa PACKAGING FOR PRODUCTS WITH ESTEMPORANEA PREPARATION, PARTICULARLY MEDICINAL, PHARMACEUTICAL, COSMETIC OR SIMILAR

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US10640275B2 (en) 2017-06-12 2020-05-05 Bio-Techne Corportion Dual chamber storage device

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US3802604A (en) * 1972-02-28 1974-04-09 Oreal Device for storing two products separately and dispensing them simultaneously
EP0093090A2 (en) * 1982-04-23 1983-11-02 CAPSULIT S.r.l. A closure for bottles and the like of the type including a breakable bottom reservoir to break during use
EP0217425A1 (en) * 1985-08-02 1987-04-08 ZAMBON S.p.A. Cap, reservoir and dropper assembly for bottles
EP0344849A2 (en) * 1988-06-01 1989-12-06 Dam Technological Research Ltd. Container cap for powders

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US3802604A (en) * 1972-02-28 1974-04-09 Oreal Device for storing two products separately and dispensing them simultaneously
EP0093090A2 (en) * 1982-04-23 1983-11-02 CAPSULIT S.r.l. A closure for bottles and the like of the type including a breakable bottom reservoir to break during use
EP0217425A1 (en) * 1985-08-02 1987-04-08 ZAMBON S.p.A. Cap, reservoir and dropper assembly for bottles
EP0344849A2 (en) * 1988-06-01 1989-12-06 Dam Technological Research Ltd. Container cap for powders

Cited By (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0577200A1 (en) * 1992-07-02 1994-01-05 Laboratorios Cusi, S.A. Pharmaceutical product container for two separate substances, having a device for mixing and dosed dispensation
US5474209A (en) * 1992-07-02 1995-12-12 Laboratorios Cusi, S.A. Pharmaceutical product container with two separate substances and a mixing device and dosed dispensation
ES2064277A1 (en) * 1993-03-30 1995-01-16 Cusi Lab Pharmaceutical-product container with two separated substances and device for mixing and metered dispensing
CN1127332C (en) * 1995-12-04 2003-11-12 库西实验室有限公司 Pharmaceutical container with two separate substances, with mixing device, dosed application and assembly process thereof
JPH09154918A (en) * 1995-12-04 1997-06-17 Lab Cusi Sa Pharmaceutical container which contains two kinds of substances being separated, and its building up
ES2128220A1 (en) * 1995-12-04 1999-05-01 Cusi Lab Pharmaceutical container with two seperate substances, with a mixing device, dosed application and assembly process thereof
AU711119B2 (en) * 1995-12-04 1999-10-07 Laboratorios Cusi, S.A. Pharmaceutical container for two separate substances, incorporating a mixing device for dosed application, and an assembly process thereof
EP0778221A1 (en) * 1995-12-04 1997-06-11 Laboratorios Cusi, S.A. Pharmaceutical container with two seperate substances, with a mixing device, dosed application and assembly process thereof
EP0921079A1 (en) * 1997-12-02 1999-06-09 Plastikwerk Expan GesmbH Two compartment container
US6073803A (en) * 1997-12-02 2000-06-13 Plastikwerk Expan Gmbh Container
AT410085B (en) * 1997-12-02 2003-01-27 Feichtinger Ernst Expan Container for separated fluids
WO1999039987A1 (en) 1998-02-09 1999-08-12 Tengiz Kekelidze Stopper
EP1087894A1 (en) * 1998-03-20 2001-04-04 Seaquist Closures Foreign, Inc Dispensing structure with frangible membrane for separating two products
EP1087894A4 (en) * 1998-03-20 2004-12-01 Seaquist Closures Dispensing structure with frangible membrane for separating two products
EP1072530A1 (en) 1999-07-19 2001-01-31 Société des Produits Nestlé S.A. An assembly for two products to be mixed just prior to use
WO2001005675A1 (en) 1999-07-19 2001-01-25 Societe Des Produits Nestle S.A. An assembly for two products to be mixed just prior to use
GB2365405A (en) * 2000-08-01 2002-02-20 Lily Hsu A container and closure assembly with multiple storage compartments
GB2365405B (en) * 2000-08-01 2004-03-10 Lily Hsu Container with separate storage spaces
US7210575B2 (en) 2002-09-26 2007-05-01 Boehringer Ingelheim International Gmbh Two-component packaging unit
WO2004031048A1 (en) * 2002-10-04 2004-04-15 Sheldon Denholm Tree Liquid dispensing device
US7114403B2 (en) 2003-05-30 2006-10-03 Oakville Hong Kong Co., Ltd Fluid collection and application device and methods of use of same
EP1687217A4 (en) * 2003-11-05 2006-11-02 Jeong-Min Lee Method and structure for mixing different materials
EP1687217A1 (en) * 2003-11-05 2006-08-09 Jeong-Min Lee Method and structure for mixing different materials
WO2005044430A3 (en) * 2003-11-10 2005-08-04 Jeong-Min Lee Method and structure for mixing different materials in the pouch container
US7617929B2 (en) 2003-11-10 2009-11-17 Lee Jeong-Min Method and structure for mixing different materials in a pouch container
US7837939B2 (en) 2003-11-14 2010-11-23 Alere Switzerland Gmbh Rapid sample collection and analysis device and methods of use
US7544324B2 (en) 2003-11-14 2009-06-09 Oakville Hong Kong Company Limited Rapid sample analysis storage devices and methods of use
WO2005087606A1 (en) * 2004-03-09 2005-09-22 Wendon Limited Volumetric dispenser
US7490719B2 (en) 2004-03-09 2009-02-17 Wendon Limited Volumetric dispenser
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Also Published As

Publication number Publication date
DE69305553D1 (en) 1996-11-28
EP0561322B1 (en) 1996-10-23
IT1259924B (en) 1996-03-28
ITMO920035A1 (en) 1993-09-19
ITMO920035A0 (en) 1992-03-19
DE69305553T2 (en) 1997-05-28
ES2096788T3 (en) 1997-03-16

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